Basic Information

Insect: Drosophila erecta
Gene Symbol: -
Assembly: GCA_000005135.1
Location: CH954181.1:14204582-14208471[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 0.00017 0.012 16.1 1.2 1 23 165 188 165 188 0.96

2 14 0.0017 0.12 12.9 3.1 2 23 237 259 233 259 0.90

3 14 0.0074 0.52 10.9 0.8 1 23 352 375 352 375 0.93

4 14 0.16 11 6.7 3.0 2 23 424 446 423 447 0.93

5 14 0.00068 0.048 14.2 0.4 1 23 516 539 516 539 0.92

6 14 2 1.4e+02 3.3 0.1 2 14 558 570 557 582 0.85

7 14 0.0013 0.094 13.2 5.6 2 23 590 611 590 612 0.95

8 14 0.0052 0.36 11.4 0.1 1 20 697 716 697 718 0.95

9 14 0.0017 0.12 12.9 0.3 1 23 750 773 750 773 0.93

10 14 0.0024 0.17 12.5 1.5 2 23 823 845 822 845 0.95

11 14 0.019 1.3 9.7 1.8 1 23 946 969 946 969 0.91

12 14 0.029 2.1 9.0 1.2 1 21 1021 1041 1021 1042 0.95

13 14 8.9 6.3e+02 1.2 2.1 2 23 1073 1096 1072 1097 0.72

14 14 3.4 2.4e+02 2.5 0.1 1 13 1115 1127 1115 1131 0.81

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	0.00017	0.012	16.1	1.2	1	23	165	188	165	188	0.96
2	14	0.0017	0.12	12.9	3.1	2	23	237	259	233	259	0.90
3	14	0.0074	0.52	10.9	0.8	1	23	352	375	352	375	0.93
4	14	0.16	11	6.7	3.0	2	23	424	446	423	447	0.93
5	14	0.00068	0.048	14.2	0.4	1	23	516	539	516	539	0.92
6	14	2	1.4e+02	3.3	0.1	2	14	558	570	557	582	0.85
7	14	0.0013	0.094	13.2	5.6	2	23	590	611	590	612	0.95
8	14	0.0052	0.36	11.4	0.1	1	20	697	716	697	718	0.95
9	14	0.0017	0.12	12.9	0.3	1	23	750	773	750	773	0.93
10	14	0.0024	0.17	12.5	1.5	2	23	823	845	822	845	0.95
11	14	0.019	1.3	9.7	1.8	1	23	946	969	946	969	0.91
12	14	0.029	2.1	9.0	1.2	1	21	1021	1041	1021	1042	0.95
13	14	8.9	6.3e+02	1.2	2.1	2	23	1073	1096	1072	1097	0.72
14	14	3.4	2.4e+02	2.5	0.1	1	13	1115	1127	1115	1131	0.81

Sequence Information

Coding Sequence: ATGGAGGGCATGGATCTGTGGACGTCGATGTTTTCCGCCGACTTCGAGGAGGGTGAGCCGGAGAGCGTGGTGACGGAACTGGAGGACAGCGAGCAGTACGGGAATGGCAATGACGACTTCCTAGGCGATACGGAGATCCTAGATTCAGGCGATGCCATCGATGACCTGCTAGATGGCGAGGATGATGAGAGAGAAGAAGAGAATGACTACGAAAAGAACTCCAAGGGGCCAGAGCAACCCGACCCCGACGACGATGCGCTCTTTGATTTTAATATGGAACCCATTGTAGATATAGCGGAGCCACAGAATCCCTCGTTGGCTCCTGCAGGTCCCATGGGCCACCAAGTGCGTGCCACAATGCAGCGACAATCCTTCCCCGGAACTTTGGGTCGACCCAGAGTGGGTCCCGGAATGTCTGTACGACCCACCACCTCGCAGATCAATGCAACGGACGAGAACGGAGTGCCAATTAATTACGAGTTGGGCGTAGTCTACATATGCCCCGCCTGCGGAGGAGAGTTCCGGCAACAGGACCACTGGAAGCGGCACATGAACCACATCCACAAGTACAACACCCTGCGTGGCTTGAACTTTACGCCGCTGGACAAGCTCTATCAGCGTTGCAGGGAGTGCAACAAACGGATTGCCATGCACAGCCGCGAGAATCTGCTTAAGCATAAGTTTACGCACCTGCCCTTCAGGTGCACCAAGTGCTACATCTGCAAGCGGGAGTACAAATACAGGCAAGATCTAATGGTTCATCTCCGCATGGTCCATTGCGATGAAGTGGTGGCCATGATGCGTGAGGGTTACAATGCGGCGGGACGAAAGACACGGGTTCGAGAATCCCGCACCGAGCAGCTGCTGCGGGACAAGAGCTTCCGAGAGAATGATGACCTTGGCGAGGATTCTGATCGCATAGAGGTGCGGAATGAGCTGCTGGAACCGGATGTCGATGAGTCTGGCACCCAGGAGCAGTCCTTGTCGGAAGAGGTTTCCAAGAAAAAGGCTGGCAGCCGAGGAGCAGCCGAACTGTGCGAGGATTACATACACTACATGTGTCCCGACTGCGGGACAGAGTGCGAGACCCACGCCCAATGGAGCCAGCACATCGAGTTTGTCCACGACTACGTCAGCCGGAGAGGACTTAATTTCCGCAGCGTGGACATGCAGATGCAGTGCCTCGAGTGCAAAAAGATTGTGACTCCCAATACCATTAAAACACTCCGAGCCCACAAATTCAGCCATTTGTCGCAGCCTGAGTGGCTGCGCTGTAAACTCTGCTACAAGGGTTACACGGATCATCAGGAAATAATCAGAcatctgctgcagcagcatcataTGGATACGCTTATGTCGGAGGAcgccgaggaggaggatggtGAAGCCCCATTGGTCATAGTGGCGGACGATGAATGCGTCGAGGATAATGGAAACGGCGAGGGAAATGGTGCACCCTTGGACGAGGATTCGCCCTACTTTGAGGACGCACCTAGGCGCGGCGGTCGCATCAGCAGCGACGACATATTCGAGCCTCACATCGACTACCTCTGTCCGCAGTGCGGCAAAGAATTCATCGAGAAGAAGCACTGGCGTACCCACGTGGTCATGGCTCATAGCATGAACGATCTGAGCAAGCTAAATTTTGAAATGATAAACGAACGGCAACTTAAATGCACTGAGTGCGATAAGATCATAACCAATGCGTATGGAATCCAGAATGCCCAGCAACACAGGATCACGCATCTTCCATTCAAGGCCTACGCCAGGTGCCGCAAGTGCCACAAGTCCTACACGGACCGGAAGGGTCTCGTAAAGCATCTGGCTACCCATCATCGCGTTGGTTGGCCACGAAAGCATTCGGGAGGATGCCCAGCTCCAATTCTTACACCCTCCAAGCAGCCACGCAAACAGATAGTAACGGTGGCCAATGAAACATACGAGATAATCTATCTGGACGACGTTGACCAAGGTGGAATGGAGGAGGATAACGACTTTGGCGAACAGATGCAGGCGGAAGAGGATGAATACCCAATTGCGCCgcctccaccaccgccacaGCCAACATCTCAAGGAAATCACCATCGCTACAAGTGCGTCCATTGTGGCACACTCTTCGCCACCCAGGCGGCTGTCCGTGTTCATATTAGCGAAAAACGTTGCAGGAAGACAGTGGTCAGAAGGCGTCGACAACCAATAATGAACTCTGCAGATCCATCCGTTCCCACAGTAGAACAAAATTACATCTTCTTGTGCCCATCCTGCGGATTTGAGTACAAGACTCAGTTCGAGTGGCGCCGTCACATCAATGAGGTGCACAATTTTGACAAGCGCCAATATCTAAACATGCGGCAGTTGGATAAGTATCGCTACCAATGCACCCAGTGCAAGGACATTGTATGCAATTCGAAGCTAAAGGGCTTGCAGGACCATCACTTCCGCCACCTGCCCTATAGACTGTACCTCAAGTGCCTGATCTGCGGCACTTGCTACAATCATAAGCCGAATATAGCGGCACATTTAAGAGCCCGTCACAGCATTTATGATAAAGAGACACCGGCGATGATCACAAAACCTAAACAAGTGCTCGGCCGTCATAAGGATAATAGTAGGAAGAACCCCAAACTGACctctcctcctccagctccagcccCGGCAGTGGCACCGGCACCAGCACCGCCCTCACCACCTGCATGTTCCTCCtctgctgcttcctctgcGAGTAGTCGTTCCCTTAAACCGCAGCCCGGTGGTTTGCCAGCCCGACCCGCTGGTCTCAACACGCTGGAGGACAGCATCTCGTACCACAATGCCGTGGACCTGGACTTCATCACGTACTTTTGCCCCAAGTGCAATCAGAACTTTGACTCTCATGCATTCTGGCGCAAACATATCGTGGAGCAACACAACTTTAACAGCCGTGAGGGCCTGAACTTTCGGCAGATCGACAACCATCACTACCTGTGCCTCGAGTGCTACAAACGGGTTACCGTAACGCACACCAAGGGTGCCATCGGGCAGCTTCAGTCGCACAAGTTCCGCCACCTGCCCCACAGATCCTTCAAGTGTTTGACTTGCGACGGTGAGTTTGTGCGCAAGCAAATGTTCTTCAAGCACCTGAACCGAGACACTAACCGGTGTGACAATCGTCCGCACCGGGATTTCGATGACGATGAGCCCGACCAAGACACGTTATTGAGCAGCATCTACCACCTATCGTGTCCGCAATGTGGTGACAACTTCAAAACTCACAATAAAAAGGAGTGGCGCGAGCACATCAACGACCACCATGGCTTGACCAAGCTGGAGCTTCTGCACATGAGCAAAGTGGGTGAGGACGTCTACCGCTGCCAGGACTGTAATGAGGAGCTGGAAACGAATCGACAGTGGGTGCTACAGTTCCATCGATTCCAGCACTTGCCACACGCGGCCTACATCCGTTGTAAACTGTGCAAGCAGAGCAGTGAAGACGGTGCTGCCGCGGCGGGTGAGTTGCACAGCCTCCGTGAGCTGCAACAGCACATTCGTAAGCACCATCCGGGTATGGGGGATGCCGAGATGATATCGCTCATCGAGCAGATAATCcaggaggagaaggagcaggaggagagCACGGAGCAAACTAATGACGGTGAAAATCATACTGGTCAGGATTCAGGACCGTATATGCCATTGCCGCCACATCTATTGGACGATGATGGCGACGTGGAATTTGAAGATCAGTATCTGCTCGGCTAG
Protein Sequence: MEGMDLWTSMFSADFEEGEPESVVTELEDSEQYGNGNDDFLGDTEILDSGDAIDDLLDGEDDEREEENDYEKNSKGPEQPDPDDDALFDFNMEPIVDIAEPQNPSLAPAGPMGHQVRATMQRQSFPGTLGRPRVGPGMSVRPTTSQINATDENGVPINYELGVVYICPACGGEFRQQDHWKRHMNHIHKYNTLRGLNFTPLDKLYQRCRECNKRIAMHSRENLLKHKFTHLPFRCTKCYICKREYKYRQDLMVHLRMVHCDEVVAMMREGYNAAGRKTRVRESRTEQLLRDKSFRENDDLGEDSDRIEVRNELLEPDVDESGTQEQSLSEEVSKKKAGSRGAAELCEDYIHYMCPDCGTECETHAQWSQHIEFVHDYVSRRGLNFRSVDMQMQCLECKKIVTPNTIKTLRAHKFSHLSQPEWLRCKLCYKGYTDHQEIIRHLLQQHHMDTLMSEDAEEEDGEAPLVIVADDECVEDNGNGEGNGAPLDEDSPYFEDAPRRGGRISSDDIFEPHIDYLCPQCGKEFIEKKHWRTHVVMAHSMNDLSKLNFEMINERQLKCTECDKIITNAYGIQNAQQHRITHLPFKAYARCRKCHKSYTDRKGLVKHLATHHRVGWPRKHSGGCPAPILTPSKQPRKQIVTVANETYEIIYLDDVDQGGMEEDNDFGEQMQAEEDEYPIAPPPPPPQPTSQGNHHRYKCVHCGTLFATQAAVRVHISEKRCRKTVVRRRRQPIMNSADPSVPTVEQNYIFLCPSCGFEYKTQFEWRRHINEVHNFDKRQYLNMRQLDKYRYQCTQCKDIVCNSKLKGLQDHHFRHLPYRLYLKCLICGTCYNHKPNIAAHLRARHSIYDKETPAMITKPKQVLGRHKDNSRKNPKLTSPPPAPAPAVAPAPAPPSPPACSSSAASSASSRSLKPQPGGLPARPAGLNTLEDSISYHNAVDLDFITYFCPKCNQNFDSHAFWRKHIVEQHNFNSREGLNFRQIDNHHYLCLECYKRVTVTHTKGAIGQLQSHKFRHLPHRSFKCLTCDGEFVRKQMFFKHLNRDTNRCDNRPHRDFDDDEPDQDTLLSSIYHLSCPQCGDNFKTHNKKEWREHINDHHGLTKLELLHMSKVGEDVYRCQDCNEELETNRQWVLQFHRFQHLPHAAYIRCKLCKQSSEDGAAAAGELHSLRELQQHIRKHHPGMGDAEMISLIEQIIQEEKEQEESTEQTNDGENHTGQDSGPYMPLPPHLLDDDGDVEFEDQYLLG*

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00592022;
90% Identity: iTF_00596968;
80% Identity: -