Basic Information

Insect: Drosophila erecta
Gene Symbol: -
Assembly: GCA_000005135.1
Location: CH954180.1:4757511-4759582[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 0.16 11 6.7 0.1 2 23 275 297 275 297 0.90

2 10 6e-05 0.0042 17.5 0.3 6 23 306 323 306 323 0.99

3 10 1.4e-05 0.00098 19.5 0.3 1 23 329 352 329 352 0.98

4 10 0.00033 0.023 15.1 0.4 1 23 364 386 364 386 0.97

5 10 0.015 1 10.0 5.5 1 23 393 416 393 416 0.97

6 10 1.2e-05 0.00087 19.7 1.8 1 23 422 444 422 444 0.96

7 10 0.088 6.1 7.5 0.4 2 23 453 474 452 474 0.96

8 10 0.00099 0.069 13.7 3.0 2 23 480 502 479 502 0.95

9 10 6e-06 0.00042 20.6 0.9 2 23 509 530 508 530 0.96

10 10 0.00019 0.013 15.9 4.4 1 23 536 559 536 559 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	0.16	11	6.7	0.1	2	23	275	297	275	297	0.90
2	10	6e-05	0.0042	17.5	0.3	6	23	306	323	306	323	0.99
3	10	1.4e-05	0.00098	19.5	0.3	1	23	329	352	329	352	0.98
4	10	0.00033	0.023	15.1	0.4	1	23	364	386	364	386	0.97
5	10	0.015	1	10.0	5.5	1	23	393	416	393	416	0.97
6	10	1.2e-05	0.00087	19.7	1.8	1	23	422	444	422	444	0.96
7	10	0.088	6.1	7.5	0.4	2	23	453	474	452	474	0.96
8	10	0.00099	0.069	13.7	3.0	2	23	480	502	479	502	0.95
9	10	6e-06	0.00042	20.6	0.9	2	23	509	530	508	530	0.96
10	10	0.00019	0.013	15.9	4.4	1	23	536	559	536	559	0.96

Sequence Information

Coding Sequence: ATGATTTGTCGCCTTTGCCTGCGATGTCTCAGTCCAGGAAGCGCAGTCTTTCTCTTTGAGACGGACGATACGCTGGCCGAGACGCGCCTGGTCAAGATGATTGCGAAGTTTCTGCAACTGGAGATCCTGCCCGACGACGGCATCTCGACCAGCGTCTGTACCGAGTGTTGCGAACATCTTGAGGACTTTAATGGCTTCTGGCAGCTGGTGGAGCAGAAACAGTGCTCACTCAAGAAGGAGTTTCTCACCGTGGACGTCGACTGTGCGGCCATGAAATGGACGGGCGGTGTCGACGTGGACGTTAACATCGACGAACTGCCGCTGGCGGCTGGCGACATGGACGAGAAACCGTTGGACCTGCACAACCTTAGCCTGCTGGGCAGCGTGCTGGACGTGAATGTGGACAGTGTGGATGTCAGGGAACCTATCAAGGAGCAGCTGCCTTGTGAgaccgaggaggaggacgagagGCCCTGCCTGCAGGCCAGTGATAGCGAACCGGAGGTGCCCGATGGGCACTCGGAATCAGAAGACTCTTCAGATGATGAACCTCTGGTCCGACTGCGAACGAAAATGAAGCCCAAGCGCAAGACCACAGGACGTTCCTCCAAGAATTCGGGTCCAATTTCGCTGCAGCAGGAGCTTGCCGATCTGTTCGACGATGGTGGCAAGCGGCGCCGTAAGAAGGCACCTGACCAGCGAGCAACCAGCGAGGTGCAGGAGACCGAGCTACAGGCCGTTCTCGAGCGCAAGCCCAAGGGCTGCTCCCGCGCTCAGCTGGCAAAGAGCTACGAGGAGGCAATTGCCAGCTACATGAGCGCCAGCTGCGACCTGTGTGACTTTAGTGCTCCCTACCTATCCGAACTGAAGACCCACTTCCTGGAGGTGCACCAGCGCGAGTACTACATCAAGTGCTGTGGCAAAATCTTCACTCGCGCTTCCAAGCTGATGGACCACATCCGCAAACATATCAACCCCAAGCTATTTACCTGCACCATTTGCCAGAAGTCGCTCAACTCGCAGGACTACCTGGCCACTCATATCGAGACGGTGCACAACAAGGTTGCCCAGATCGGCAAGGTGCTCAAGTTTCCGTGCCCCAAGTGCGAACGGACCTTCAGTAGCGAGCGCCGTATGGCCAATCACTTGGCCAAGCATGACACCGACCAACTGGAACACACCTGCGAGATTTGTTGCAAAAGCTTTGCCAACGTGCACCGCCTGCGAAGGCACATCCAATCCATCCACGAAGACCTGCATCGTCACGTTTGCGACATCTGCGGCAAGAAATTCAAGTTCAAGCCCTCCTTCGAGCGCCATTTGCTGGAACACCAGGGCGTGGTGGCCCCGGCAGTGGAATGCCCCGTCTGCGGAGTGTGGCTGAAGAACGAGCACAGCTTGCGCCTGCACCGCTTTACGCACGACAGCACGGACACCGTGTGCCCGCACTGTAGCAAGACCTGCACCTCGCGCACAGCGCTCCGCGGTCATGTGAAGTATGCCCACAAGCTGACCACCAATCTGCAGTGCACGTTCTGCGAGAAAACCTTCAAGCAGCAACGCAACCTGGACGAGCACATGGCCATCCATGCGGGCCTGCAGCTGTACAACTGCCCGCATTGCCCCAAGGAGTGCCGCTCCCGCTCCAACATGTATGTCCACATCAAGCAGCGGCACGCGGAAGAGTGGCTGCGCGCCAAAATGGCACGCTCGCACAATCCGCAGTTCAAGCCGGCCGACGTTTAA
Protein Sequence: MICRLCLRCLSPGSAVFLFETDDTLAETRLVKMIAKFLQLEILPDDGISTSVCTECCEHLEDFNGFWQLVEQKQCSLKKEFLTVDVDCAAMKWTGGVDVDVNIDELPLAAGDMDEKPLDLHNLSLLGSVLDVNVDSVDVREPIKEQLPCETEEEDERPCLQASDSEPEVPDGHSESEDSSDDEPLVRLRTKMKPKRKTTGRSSKNSGPISLQQELADLFDDGGKRRRKKAPDQRATSEVQETELQAVLERKPKGCSRAQLAKSYEEAIASYMSASCDLCDFSAPYLSELKTHFLEVHQREYYIKCCGKIFTRASKLMDHIRKHINPKLFTCTICQKSLNSQDYLATHIETVHNKVAQIGKVLKFPCPKCERTFSSERRMANHLAKHDTDQLEHTCEICCKSFANVHRLRRHIQSIHEDLHRHVCDICGKKFKFKPSFERHLLEHQGVVAPAVECPVCGVWLKNEHSLRLHRFTHDSTDTVCPHCSKTCTSRTALRGHVKYAHKLTTNLQCTFCEKTFKQQRNLDEHMAIHAGLQLYNCPHCPKECRSRSNMYVHIKQRHAEEWLRAKMARSHNPQFKPADV*

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00492388;
90% Identity: iTF_00505566;
80% Identity: -