Basic Information

Insect: Drosophila erecta
Gene Symbol: zfh1_2
Assembly: GCA_000005135.1
Location: CH954181.1:9929637-9933772[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 9.5e-05 0.0066 16.9 1.3 1 23 140 162 140 162 0.97

2 15 0.00085 0.059 13.9 1.2 3 23 170 190 168 190 0.94

3 15 0.0009 0.063 13.8 0.3 1 23 340 362 340 362 0.98

4 15 0.00064 0.045 14.3 0.8 1 23 368 390 368 390 0.98

5 15 1.2e-05 0.00082 19.7 2.0 1 23 421 443 421 443 0.97

6 15 0.0029 0.21 12.2 0.7 1 23 473 495 473 495 0.93

7 15 0.011 0.77 10.4 1.3 1 23 501 524 501 524 0.97

8 15 0.027 1.9 9.2 0.4 3 19 533 549 532 550 0.95

9 15 0.00016 0.011 16.2 5.6 1 23 559 581 559 581 0.97

10 15 0.047 3.3 8.4 0.4 2 23 587 608 586 608 0.96

11 15 9.3e-06 0.00065 20.0 1.0 1 23 617 639 617 639 0.98

12 15 0.0011 0.074 13.6 0.1 3 23 647 667 645 667 0.97

13 15 5.7e-05 0.004 17.6 0.5 1 23 673 695 673 696 0.95

14 15 2 1.4e+02 3.2 0.5 1 23 706 728 706 728 0.95

15 15 0.0056 0.39 11.3 0.2 1 23 1258 1280 1258 1280 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	9.5e-05	0.0066	16.9	1.3	1	23	140	162	140	162	0.97
2	15	0.00085	0.059	13.9	1.2	3	23	170	190	168	190	0.94
3	15	0.0009	0.063	13.8	0.3	1	23	340	362	340	362	0.98
4	15	0.00064	0.045	14.3	0.8	1	23	368	390	368	390	0.98
5	15	1.2e-05	0.00082	19.7	2.0	1	23	421	443	421	443	0.97
6	15	0.0029	0.21	12.2	0.7	1	23	473	495	473	495	0.93
7	15	0.011	0.77	10.4	1.3	1	23	501	524	501	524	0.97
8	15	0.027	1.9	9.2	0.4	3	19	533	549	532	550	0.95
9	15	0.00016	0.011	16.2	5.6	1	23	559	581	559	581	0.97
10	15	0.047	3.3	8.4	0.4	2	23	587	608	586	608	0.96
11	15	9.3e-06	0.00065	20.0	1.0	1	23	617	639	617	639	0.98
12	15	0.0011	0.074	13.6	0.1	3	23	647	667	645	667	0.97
13	15	5.7e-05	0.004	17.6	0.5	1	23	673	695	673	696	0.95
14	15	2	1.4e+02	3.2	0.5	1	23	706	728	706	728	0.95
15	15	0.0056	0.39	11.3	0.2	1	23	1258	1280	1258	1280	0.97

Sequence Information

Coding Sequence: ATGAACAACCAGCGATATGGCGGCATCCAGTGGATACAGCACCACGTCTCCGCGGGCGACTCCTCCGAGGTGGACATCCTGGAATCGGATGGCGGAGCAGGGGCCTCGGGCGAGGATCTGGACCATATGGCAGCCGAGAATCTTATATTCATGGCCCGCGATGGTCAGCTGAGTGAGATAATGGCGGCCAACGAGGCGGGCAGAACGGTTCTGGTCACCGCCGACGGCACCACCGTTGCCTATGCGGAATCCTTCGACGATGACGCCCAGGTGGTCACCGAGGAGGTAATCACAGACGACTGGGTGCAGCACCAAGGCGCCGAACGTGTGGAGATCGCTGCCGAGCAGATAGCTGGGATAAGTAGCTCACAGGAGCTGTTGGACATGGAGCAGGATGAGTACACTGCGCTAAGGCCCTATCCTTGCGACTTTTGCAGCCGGCGCTTTCGCAAGAAGGTCACCTTAAATACCCATATGTTGGCCCACCAAAATGATCGACCGCATCTCTGCAAGCTGTGTGGCGCGCGATTCTCACGACGAGCTGAGCTTATCAGCCACTTCAAGGCACACGCAGAGGCCCAGGATGCGGCCGATGCCGaggcagcagccgccgcaaCCGATTCATCTTCTGCCATTAAGTTCGAGCATCAGACGCAGCGACAAATGGACGATCACTACTACGAGCAGGATTGGCCACTTTtccaacagcaacaggagcaggaacagGCGCAACAGGAAATCCATCAACAGCATCAGATTGTGGAGGAGGGCGAGGTACAACTGGTGGCCAGTTACCCAGCCACGGTGGATCCACCAGCAGCTCCGTCACGAGGCAGAATAAGTCGCTTGAAGCCCAAGGAAGAGAGCAGCCAGTTCATTGAGATTTCCAAGTCAGCGGGTGATTCGAGGTCATACATGGAGCCTGAGCCGGCTCAGCCTGTGGTTACCACGTCGCAGCCTATTGCCATCGACCCGCCTCCTCAACCAAACTTTCCGGTGCTGGACGACAGCAAACCCTTTGTGTGCCAGCAATGCGGATTGGCCTTTGCGCGGGAAAAGGCGTTCGTTTCACACACCAAGAATCACCGCGTGGACTCGCTTTTCGAATGCAACCAGTGTCAGGAGATGTTCTGGGACAATAACAGCTTGCAGGAGCACCAGAAGACTCATCAGTTCGAGGAGAGCAACTCGGAGTACGATCCTGCCTCGGCAGAGGATAGCGGCAGCGAATCGGAGCCCGACGAGCAGTTGTATGGCGAATTTTATTGCAACGAATGCGGGATCTCCTTTCATCGCCAGGACCTACTTCGACGTCATGCCAAACTGCACTATAAGCCAACGGAGCAGGCGGCTGGTGGAAGCAATTCCGATGTCACTGCTGGCGGGGATGAGGAGCATGCCAAAGATTCTACTGGACACTGTTGCAACACTTGCGGAAAGTCCTTTCCTAGCGCTTTGGAGATGCTCGCCCATGCAGAAATCCATGCTAGGTTCCCGCCTTTCAAGTGCGTCCTATGCGGAATTAGCTTTTACGAGGAGCAAGCGATTAAGCGCCACCTGCACACCCGCCATCCCAGTGAACTGAAGGCCAATTCATGCGTCCTGTGCGGCAAAGAGTGCCGCGATCGCAAGGCTCTGATAAAGCACGCCTGGGACCATTCGCGCGAGAAGTGCCATTCGTGCTCCAAGTGCGGCAAGAACTTCCACAACAAGGCGCGTCTAAAGCGGCACATGGCTTCGCATCGCGACAAGTCGGTAGTATGCGAGGTGTGCCAGGAGGAATTCCCCGACGGACGAACGCTCTCCAACCACCGACACTCGCACAGCACTACCTCGCCTGGCAAACTGTTCCCGTGCCACGAATGCGGCAAGACGTTTGGTTCGCGCAGCTCCCAGCAGATCCACGTACGGATCCACACTGGCGAGCGGCCATATGGCTGCCGCTACTGCTGGAAGGCTTTCGCGGATGGTGGTACACTGCGGAAGCACGAGAGGATCCACACCGGAGAAAAGCCCTATGCCTGCTCTGTCTGCCCACGCGCCTTTAACCAACGGGTAGTGCTGCGGGAACACATTCGCTCTCATCATTCTGGGCTGGATGTAACGCGGAACACCTACCACTGCACAGTCTGTTCCGAAGACCTGTTGACTTCCAATGACCTCATCCAGCACCTGATCCAACATAGCGACTCAAACACAGCTAAGCAGCGACAGCCTGTTACGGGACCGCGCAAGTACAAGCGTCGTCGTAAGCTACAGCCGCACGAGATAGCTCACATGCGGGCGGAGAACAGGGATGCCAACGGTGAAGAGGAAGAGGCCGTAGGAGAAGGCGATGCAGAGGAGTATGCCAGTGACATCGATCTTTGCGACTTTGATGTCGAGAACGTGGACGACATCTTTGACATGGCAGAATCTCCTAAGAAGGAAAAGCGGAAGAGGGGCTCGGCAGCCACAAAAGCTGATCCAAAACCCGTGAACAATGGGAAAGCGGTGAAACCTCCTCAGGAAAGGGGCAATGCTAAGCCAAGATATGACTCCACCAGCAGTCAGCAATCGGATCGCATTTGGGAGGAAAAGTTCCTTCACGACAGTCAAGTGGCTCTCTTTCAGATCGATTCGCTGGTAGTGGTAAATGACACTCATCTGCAGCCCGCTAGCTCTGCTGTGTCTTCGAACATACCCAATACAAGAGGCGGATCGAAGCAGCAGGGAAAAGTGCAGGCGAAGTCTGTAGAAGGAGCCGGAAATTTCAATAGCTCAGCTACCACATCTGTCTCTTCAGTCTCCGCCACCACCTCCACATCCAGCAGTCGGAGCCGGAGGAGGGCGGCAACCACTAAGACAGCCAGCAAAGCACCTCCTGCCAGTAATTCGCGACCCCGAATGATTCACACAGAGAAAGCCAAGGTGTCAAGAGGAGCTGGCGGAGACTCCTCTAGCAGTTCGGCAAAGAAAACGCGCTCCAAGACCTATATTAGTCGCACGGAGTCGAATAATCTAAGCCTCGACAAAACCCGCAGCAGTGCCTCAAACATGGTGGATGACTATGAAATCATTTCCCCAGCTACCCATCCGCCAAATCAGATCAGCTCCAGTCCGTTACACATcaaacaggagcaggagcaacaacagcgTGTCCAACTTATGTACGATGATAATTTACTGATAGATGCTGCTATGCTCAGGGAGAAGACCTATGAGAAGTTTAACCCGAGCATTGTTAATGATCTGGAGGAGATACTGCGCTCTCCGCTGAAGCACGAGAGAAATTCTCGTCTTCGCTTTACCAGCGAGTCCTCCACCACGCCACAATATCTGCCCGAAGAAGAGCAAAACCTCATTAAAATTGAGCCAACTTCTCCGGATCTGCGGGAAATGTTGGAGAGCCAGCAAAGAGTCACAGCCCATAGCACCAGCACTCCTTCGTCCTCTTCATCTGCTAGAACTTCCAGACATCTGCGTCAAATCACTGCCAATGGTGCACGGGCAGGGAGCAAGAGATCTCCAGGTGGCGTAGCCAGCAAATCGTCGGCAAACTCGGGAGTGGTGgccaaaaaagcaaacactGCCACCAAAGTGAGCAGCAGCTCATCCTCGTACCTCTCTTACGGGGTGGATTCCTACAATGTAAACGTACCTGCCAGTGCCAACAACGCCGATGTGGGCGGCGGATTCTTTTCCATCTCGGAGGTTGTTTCTGCAGCCGACGCCGCGGATGCGGCTGCTAAAGCGGCGGCAGCTGGTAAATCGGAGCGGAAAACCCGCAGCTTCGAGTGCGAAATGTGCTCGGCCATCTTTTATGATCGTGCCCAACTGCTGGAACATGTGCACATTCACATTTAA
Protein Sequence: MNNQRYGGIQWIQHHVSAGDSSEVDILESDGGAGASGEDLDHMAAENLIFMARDGQLSEIMAANEAGRTVLVTADGTTVAYAESFDDDAQVVTEEVITDDWVQHQGAERVEIAAEQIAGISSSQELLDMEQDEYTALRPYPCDFCSRRFRKKVTLNTHMLAHQNDRPHLCKLCGARFSRRAELISHFKAHAEAQDAADAEAAAAATDSSSAIKFEHQTQRQMDDHYYEQDWPLFQQQQEQEQAQQEIHQQHQIVEEGEVQLVASYPATVDPPAAPSRGRISRLKPKEESSQFIEISKSAGDSRSYMEPEPAQPVVTTSQPIAIDPPPQPNFPVLDDSKPFVCQQCGLAFAREKAFVSHTKNHRVDSLFECNQCQEMFWDNNSLQEHQKTHQFEESNSEYDPASAEDSGSESEPDEQLYGEFYCNECGISFHRQDLLRRHAKLHYKPTEQAAGGSNSDVTAGGDEEHAKDSTGHCCNTCGKSFPSALEMLAHAEIHARFPPFKCVLCGISFYEEQAIKRHLHTRHPSELKANSCVLCGKECRDRKALIKHAWDHSREKCHSCSKCGKNFHNKARLKRHMASHRDKSVVCEVCQEEFPDGRTLSNHRHSHSTTSPGKLFPCHECGKTFGSRSSQQIHVRIHTGERPYGCRYCWKAFADGGTLRKHERIHTGEKPYACSVCPRAFNQRVVLREHIRSHHSGLDVTRNTYHCTVCSEDLLTSNDLIQHLIQHSDSNTAKQRQPVTGPRKYKRRRKLQPHEIAHMRAENRDANGEEEEAVGEGDAEEYASDIDLCDFDVENVDDIFDMAESPKKEKRKRGSAATKADPKPVNNGKAVKPPQERGNAKPRYDSTSSQQSDRIWEEKFLHDSQVALFQIDSLVVVNDTHLQPASSAVSSNIPNTRGGSKQQGKVQAKSVEGAGNFNSSATTSVSSVSATTSTSSSRSRRRAATTKTASKAPPASNSRPRMIHTEKAKVSRGAGGDSSSSSAKKTRSKTYISRTESNNLSLDKTRSSASNMVDDYEIISPATHPPNQISSSPLHIKQEQEQQQRVQLMYDDNLLIDAAMLREKTYEKFNPSIVNDLEEILRSPLKHERNSRLRFTSESSTTPQYLPEEEQNLIKIEPTSPDLREMLESQQRVTAHSTSTPSSSSSARTSRHLRQITANGARAGSKRSPGGVASKSSANSGVVAKKANTATKVSSSSSSYLSYGVDSYNVNVPASANNADVGGGFFSISEVVSAADAADAAAKAAAAGKSERKTRSFECEMCSAIFYDRAQLLEHVHIHI*

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00605719;
90% Identity: iTF_00592529;
80% Identity: -