Basic Information

Insect: Drosophila ercepeae
Gene Symbol: -
Assembly: GCA_018150545.1
Location: JAECWL010000192.1:8992346-8996578[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 2.1e-05 0.0014 18.7 0.5 1 23 161 184 161 184 0.96

2 14 0.0028 0.19 12.0 2.8 2 23 233 255 229 255 0.88

3 14 0.0031 0.22 11.9 0.6 1 23 354 377 354 377 0.93

4 14 0.29 20 5.7 5.3 3 23 427 448 425 449 0.95

5 14 0.00029 0.02 15.1 1.1 1 23 510 533 510 533 0.92

6 14 7.2 5e+02 1.3 0.0 2 14 552 564 551 576 0.83

7 14 0.0052 0.36 11.2 0.9 3 23 585 606 584 606 0.92

8 14 0.0009 0.063 13.6 0.8 1 23 699 722 699 722 0.97

9 14 0.0013 0.088 13.1 0.2 1 23 753 776 753 776 0.92

10 14 0.002 0.14 12.5 1.5 2 23 826 848 825 848 0.95

11 14 0.02 1.4 9.4 2.1 1 23 940 963 940 963 0.91

12 14 0.011 0.75 10.2 1.0 1 21 1015 1035 1015 1036 0.95

13 14 3.8 2.7e+02 2.2 0.1 2 23 1073 1097 1072 1097 0.74

14 14 0.59 41 4.7 3.0 1 23 1115 1139 1115 1139 0.87

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	2.1e-05	0.0014	18.7	0.5	1	23	161	184	161	184	0.96
2	14	0.0028	0.19	12.0	2.8	2	23	233	255	229	255	0.88
3	14	0.0031	0.22	11.9	0.6	1	23	354	377	354	377	0.93
4	14	0.29	20	5.7	5.3	3	23	427	448	425	449	0.95
5	14	0.00029	0.02	15.1	1.1	1	23	510	533	510	533	0.92
6	14	7.2	5e+02	1.3	0.0	2	14	552	564	551	576	0.83
7	14	0.0052	0.36	11.2	0.9	3	23	585	606	584	606	0.92
8	14	0.0009	0.063	13.6	0.8	1	23	699	722	699	722	0.97
9	14	0.0013	0.088	13.1	0.2	1	23	753	776	753	776	0.92
10	14	0.002	0.14	12.5	1.5	2	23	826	848	825	848	0.95
11	14	0.02	1.4	9.4	2.1	1	23	940	963	940	963	0.91
12	14	0.011	0.75	10.2	1.0	1	21	1015	1035	1015	1036	0.95
13	14	3.8	2.7e+02	2.2	0.1	2	23	1073	1097	1072	1097	0.74
14	14	0.59	41	4.7	3.0	1	23	1115	1139	1115	1139	0.87

Sequence Information

Coding Sequence: ATGGAAGGAATGGATCTCTGGACGTCGATGTTCTCTTCGGATTTCGATGAGGGGGAAGGCGAGGCGGAGGCAGATGTTTGCCTGGATGGAGAGGTTGGGGAGGATGGCGATGGACAGTACGGCAATGGAAATGGAAATTCGGATATTTTGGATGCAGACATGGGCGATGACGATGTCCTGGATGGTGAGGAGGAGGACGACGATGACGATGGCGAGGGGGAAAATAGGGGGAAACGCTCCGGTCCCGATCCCGACGATGATGCCATCTTTGACTTTGAACTGGAGCCCATGACGAGCCTGTCGGAGCAGCCGGAGCAATCGTCGTCTTCGGAAGGGGCAGGGCCCACAACGCGCAGGCAGTCCCTACCCTCGTCCCAGGGCGGCAACCCACATCCCGGCTCTTCCCAGCGGCCAACTACCTCGCAGATCAATGCCACGGACGAGAACGGAGTTCCCATCAACTACGAGCTGGGCGTTGTCTATATTTGTCCCGCCTGCGGTGCCGAGTTCCGGCAGCAAGATCACTGGAAACGCCACATGAACCAAATGCACAAATACAACACCCTGCGAGGCCTCAACTTCCTCCCTGTGGACAAGTTGTACCATCGCTGTCAGGAGTGCCACAAGCGGATTGCCATGCACAGCCGAGAGAATCTCCTCAAGCACAAGTTCACCCACTTGCCGTACAGGTGCACCAAGTGTTATATTTGTAAAAGGGAATACAAATACAGGCAAGATCTTATGGTGCACTTGAGACTAGTGCACTGCGAAGAGGTCGTGGCCATGATGCGGGGAGGCTACAATGCGGCGGGTCGCAAAACGAGAGTTCGAGAGTCACGCACGGAGCAAATGCAGAGGGAAGGCGACTTCCCCGACGACGGAGATCGCATCGAGGTACGCAACGAGCTGCTGGAGCCGGATGCGGATGAGACAAATGTAATGGAGCATTCAGCGCACTCGATAGTCGCAGAAGAAGCACATCCTGTTGTCAAGAAAAAGCATTCTGAGGGCGAAAACGATGACGTTTTGGCATCGGAGCTGTGCGAGGACTACATACATTTTATGTGCCCCGATTGCGGCACCGAATGCGACACTCTGAGGCAGTGGCGCCAGCACATCGAGTTTGTTCACGACTATGTCAGCCGGCGAGGACTCAACTTCCGCAGCAGTGACATGCAGATGCAGTGTCTCGAGTGTAAGAAGATTGTAACCCCAAACACCATAAAAACGTTGCGAGCCCACAAGTTTAGTCATTTATCGAATCCGGAATGGATGCACTGCAAGCTCTGCTACAAGGGCTTCTCCGACCACGTCAAGGTGGTAAAACATCTGATGAAGGAGCACCACCTGGACACCCTAATGCCAGAGCGTACGGAGAACAGTCCGGCAGAAGACGATTTCGATGATGGTGGAAGTAAAGAGGAAGGTACCGGGGATGCCCTGGACGACGAGTCTCCCTATTTTGCGGATGCACCGAGGCGTGGGGGTCGCATCAGCAGTGACGATATTTTCGAGCCCTTTATAGACTATCTCTGCCCGCAGTGCGGCAAGGAGTTCCGCGAAAAGAAGCACTGGCGCACCCATGTGGTCATGATGCACGGCATGAATGATCTGTCAAAGCTGAACTTCAATGTGATAGACGAAAGGAAGCTAAAGTGCCTCGAATGCGACAAAATCATCACGAATGCCTATGGCATCCAGAATGCGCAGCAGCACAGGATCACCCATCTGCCATTCAAGGCCTATGCCAGGTGCATAAAGTGCCAGAAGTCGTACACGGATAGGAAGGGTCTGGTCAAGCATCTGGCCACCTACCATCGCATAAATGATCTGCCACGACGATCGGGGGGAGAATCTGGCGCAGTGAGGGAACCCGTTCCGAAACAACCTCGAAAGCAGATTGTCACTGTAGCTAATGAGACTTATGAGATAATCTACCTGGACGACATTGAGCCGGCCGTTGAAGAGGACAACGACTTTGGGGAGCAGATGCAGGGGGAAGAAGAGGATTACCTCCCGGCAACGATTGCACCTCCCTCGCCACCCATGCAGCCGCCTTCGTCGGGGCACGTCGCACAAAAGGACACACATCGCTACAAATGCGTTCACTGCGGCGATGTCTTCACCAGCCAGGTGGCCGTTAAGCAGCACATCAAAGAGAAGCACTATAAGATTCGAAAGAGATTGCGCAGCCACCAGCACACTCCAACCTCGGAGAGCTTTGCCCCCTTGCCCACGGTAGAGCAGAACTACATCTTCCTGTGTCCCTCCTGCGGCATGGAGTATAAAACGCAGTTTGAGTGGCGGCGCCACATCAACGACGTCCACAATTTCGACAAGCGGCAGTATCTGAACATGCGGCAGCTGGACAAGTACCGCTATCAGTGCACCCAGTGCAAGGACATTGTGAGCAACTCGAAGCTCAAGGGCCTGCAGGACCATCACTTCCGTCACTTGCCATACCGATTGTACTTGAAGTGCCTGATCTGCGGCACCTGCTACAATCACAAGCCGAATATTGCCGCCCATTTGAGGGCTCGTCACAACATCTTTGAGAGAGGGGCTCCTGTGATGATAACCAAACCGAGCAAGCAAATGAGCCAACGTTATCGGGAGGATAACAAGGAGAAGACCCGACTTCCGTCTCCAATTCCTCTGCCTGAATCTCCACCCAGCTGCTCGTCCTCCACTTCTGGGGCTGCTCTCAGTCGCACCCTGAAGCCTCAGCCAGGAGCGTTGCCCGTTCGACCCGCCGGCTTGAACACCCTCGAGGATAGCATCTCCTATCACAATGCCGTGGATTTGGACTTCATTACCTATTTCTGCCCAAAGTGCAACCAGAACTTTGACTCGCACGCTTTTTGGCGGAAGCACATTGTGGAAAAGCACAACTTTAACAGTCGCGAGGGACTGAACTTCCGGCAGCTGGATAATCATCACTACCTTTGCCTGGAGTGCTACAAACGGGTGACAGTAACCCACACGAAGGGCGCCATCGGGCAGCTGCAGTCGCACAAGTTCCGCCACCTGCCGCATCGCTCCTTCAAGTGCTTGACCTGCGGCGGAGAGTTTGTGCGCAAACAAATGTTCTTCAAACATCTCAATCGGGACACCAATCGCTGCGACAATCATCCGCAGCGGGAAGTGGATGACGAGGAGCAAGAACCAGATCAAGAACCCGAAGCAAAGGTGCCAATACGCTACATGTATCAGCTGTCGTGTCCGCAGTGCGGCGATGGTTTCACCACGGTGAAGAGAGGTGGCTGGAAGGAGCACATTAATGTTTACCACAGTCTTGCCAAGCTGGATTTGCTGCACATGACCAAGATTGACGTGGATCTCTACCGCTGCAATGATTGCAACAAAGACATTCGGACCACTCGTCTGCAAGAGCTGCAGCATCACCGATTCCAGCACCTGCCCCATCCTGCCTATGTGCGCTGCAGGTTGTGCGATGACAATGAGGAATCAGGAGGCTGCCGGCTGCACAGTTTGCAACAACTGAAACAGCATATCCTGGATAGGCATCAAGGAGCAAAAGAAAAGGATGCCCTGCTCGCCAAGATCCGCGACCATATGCGCAAGGATGAGCAGGAGGATGTAGTGCCAACTGGAGATGATGATTCAGGTCCATATATGCCATTGCCCCCGCACTTGTTGGATGACGGAGACGATATGGACTTCGAGGACCAATATCTGCTGGGATAG
Protein Sequence: MEGMDLWTSMFSSDFDEGEGEAEADVCLDGEVGEDGDGQYGNGNGNSDILDADMGDDDVLDGEEEDDDDDGEGENRGKRSGPDPDDDAIFDFELEPMTSLSEQPEQSSSSEGAGPTTRRQSLPSSQGGNPHPGSSQRPTTSQINATDENGVPINYELGVVYICPACGAEFRQQDHWKRHMNQMHKYNTLRGLNFLPVDKLYHRCQECHKRIAMHSRENLLKHKFTHLPYRCTKCYICKREYKYRQDLMVHLRLVHCEEVVAMMRGGYNAAGRKTRVRESRTEQMQREGDFPDDGDRIEVRNELLEPDADETNVMEHSAHSIVAEEAHPVVKKKHSEGENDDVLASELCEDYIHFMCPDCGTECDTLRQWRQHIEFVHDYVSRRGLNFRSSDMQMQCLECKKIVTPNTIKTLRAHKFSHLSNPEWMHCKLCYKGFSDHVKVVKHLMKEHHLDTLMPERTENSPAEDDFDDGGSKEEGTGDALDDESPYFADAPRRGGRISSDDIFEPFIDYLCPQCGKEFREKKHWRTHVVMMHGMNDLSKLNFNVIDERKLKCLECDKIITNAYGIQNAQQHRITHLPFKAYARCIKCQKSYTDRKGLVKHLATYHRINDLPRRSGGESGAVREPVPKQPRKQIVTVANETYEIIYLDDIEPAVEEDNDFGEQMQGEEEDYLPATIAPPSPPMQPPSSGHVAQKDTHRYKCVHCGDVFTSQVAVKQHIKEKHYKIRKRLRSHQHTPTSESFAPLPTVEQNYIFLCPSCGMEYKTQFEWRRHINDVHNFDKRQYLNMRQLDKYRYQCTQCKDIVSNSKLKGLQDHHFRHLPYRLYLKCLICGTCYNHKPNIAAHLRARHNIFERGAPVMITKPSKQMSQRYREDNKEKTRLPSPIPLPESPPSCSSSTSGAALSRTLKPQPGALPVRPAGLNTLEDSISYHNAVDLDFITYFCPKCNQNFDSHAFWRKHIVEKHNFNSREGLNFRQLDNHHYLCLECYKRVTVTHTKGAIGQLQSHKFRHLPHRSFKCLTCGGEFVRKQMFFKHLNRDTNRCDNHPQREVDDEEQEPDQEPEAKVPIRYMYQLSCPQCGDGFTTVKRGGWKEHINVYHSLAKLDLLHMTKIDVDLYRCNDCNKDIRTTRLQELQHHRFQHLPHPAYVRCRLCDDNEESGGCRLHSLQQLKQHILDRHQGAKEKDALLAKIRDHMRKDEQEDVVPTGDDDSGPYMPLPPHLLDDGDDMDFEDQYLLG

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00615746;
90% Identity: iTF_00546249; iTF_00615174;
80% Identity: -