Basic Information

Insect: Drosophila ercepeae
Gene Symbol: pita
Assembly: GCA_018150545.1
Location: JAECWL010000161.1:5599248-5601226[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 0.00059 0.041 14.1 0.1 1 23 232 254 232 254 0.96

2 10 3.4e-06 0.00024 21.2 1.4 1 23 260 282 260 282 0.97

3 10 1.6e-06 0.00011 22.2 3.0 1 23 288 310 288 310 0.99

4 10 0.0007 0.049 13.9 0.3 1 23 316 338 316 338 0.97

5 10 3.2e-05 0.0022 18.1 0.1 1 23 344 366 344 366 0.94

6 10 9.9e-05 0.0069 16.6 1.4 1 23 372 394 372 394 0.94

7 10 0.00045 0.032 14.5 5.0 1 23 400 422 400 422 0.99

8 10 3.9 2.7e+02 2.1 1.5 1 23 431 453 431 453 0.92

9 10 0.59 41 4.7 0.0 2 23 459 480 458 480 0.95

10 10 0.2 14 6.2 0.4 1 23 486 509 486 509 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	0.00059	0.041	14.1	0.1	1	23	232	254	232	254	0.96
2	10	3.4e-06	0.00024	21.2	1.4	1	23	260	282	260	282	0.97
3	10	1.6e-06	0.00011	22.2	3.0	1	23	288	310	288	310	0.99
4	10	0.0007	0.049	13.9	0.3	1	23	316	338	316	338	0.97
5	10	3.2e-05	0.0022	18.1	0.1	1	23	344	366	344	366	0.94
6	10	9.9e-05	0.0069	16.6	1.4	1	23	372	394	372	394	0.94
7	10	0.00045	0.032	14.5	5.0	1	23	400	422	400	422	0.99
8	10	3.9	2.7e+02	2.1	1.5	1	23	431	453	431	453	0.92
9	10	0.59	41	4.7	0.0	2	23	459	480	458	480	0.95
10	10	0.2	14	6.2	0.4	1	23	486	509	486	509	0.91

Sequence Information

Coding Sequence: ATGCCTGGATACATCTGCCTGGACTGCCGGCTCCTGTTCGAGCACTGCTACCGTTTCAAGCAAATGTGCAAGAGGGCGGACACTTTGCTTCGCCAGTTTCCCTTGACCGGAACTTGGCCCGCGCCCCTTGAGAAACCGCGAGCTCCAATGGTTTCCGGGCAAGCTGTGGCCATAACGATCAATAAGAAAGACCCGCCAGTGTCTATTTCCCCTGAATTGAAACCGAAAATATTACTCAATACCATGGCCAAGGCAAACAACAAGGTGGTCATCGAAAATGTCGAGATTTTGGAGACGAATTTGCTGAACAAAAATCTACCTTCCAAGGCGGTCATAAACACTACGATTCGTTCGCAGCCCTATCAGTTAAAGGTAGATAATAACCAGGAGCTGTCCATGGATGATGTGCAAAATATGCTGGAGGATATGGCCAATGAACTAGATGAGATACCTTCGCCGCAGAAAGAGGTTTTCCCACAACAATCGCCCAACAAGCCCAAGGTTTTGAATAAATCTTCGATCAGGATACTCAATAAGGGACCCGCGGCTCCCCTCGAACCTCGCATAGCGACACCGCAAATAAAGCGGGACGAGAGCGGAAATGTGGCTATTGTCACGGAGATCCTGGACCCCAATACTCTGGTGGTTCAAGAGGATCTGGTTAAAAATGCAGAGCAAGTTCCAACCAATGTCTTTCCTTGCCCGGACTGTGAACGATCCTTTCCACTGCAGCAGTTGCTCGACATTCATCGGTTGAACCACACACGAAAGCGAAGCTTCCAGTGTCCCGACTGTGACAAGAGCTTCTTTTCAAAGTACGATATGGCCAAGCACACCTTTATCCACACAGGCGAACGGCCCTTCAAATGCAGTGTTTGTGAGAAGGGTTTCACCCGAAAGGCATTGCTCCACCGGCACGAGCGCACTCACACGGACATTCCCAAGTTTATCTGCGTGTACTGCGAACGTCCATTTATTTCGCGCCAGGAGATGGAGAAGCACGCTCAACGACATACCAAAAAACGGCCCTTCCCTTGCGGTGTCTGCGGCAAGTCATTTGCTTTCAAACAGGGTCTGGAGCGTCATGAGGTAATCCACCAATCGAACCTTCCCTTCCCTTGCCAGCACTGCCCGAGATCCTTCCCTACGGCTTGTAAACTGGCACGTCATTTGGTGGCTCACGCCGGCAAGAGGGTCTATCCCTGCAAATATTGCCCCAAGTCGTATTTGTTGTCTCACCATCTGTCCCGGCACTTGCGAACTCACAAGCAGGCCACCGACGATTCCTCATTCACGTGCAGTGAGTGTAGGGACACGCATACTAGCTACGACAGTTTGATTGAGCACTCTCAGATCCATGCATCTATGTCGCTTAAGTGCACACTCTGTCGCGAGGAGATCGGGGACGCCGATGGCGTTGAAACCCATATGCAGCTGCACAGGGAAAGCGAGAGATTTGCATGCGAGTTCTGCGACCACATCTTCCTGAGCCAGGCACAGGCGCAGAAGCACATTGAGGACGACCATGTGGTGGAAATGGTTCCTTACAACAATGAAGATGAGGGTGAAGGCGACAACGAAGGTGAAGGCGAAGGCGAAGTCGATAGCGAGAGCGATGCCGAAAAGGATTTGAAGGAGGAGCCAACGGAAGACCCTAAAGAAATTGAAATAAAGGAAGAATTTTTGGAGGAATTCTTGGACGATAAAGACGATTCAGATTCTTCGTTTAGCCCGACTCCCATGAAACGTCGTAAAACTAGTCCAGCTAAAGGAAAATCAGTTGAAGCTCCGAAAGGAGAGAAGCGGCAGACTCGCAGTCAGGACCGTGGCAAGGTAAACAAGGTTGCTCCAAAGAAAGATGTCGCGGTTGCAGCCAAGCAGGGCCGTTTGTTGGGGAAACAGGGAAAGTGGCATAAGATTTAA
Protein Sequence: MPGYICLDCRLLFEHCYRFKQMCKRADTLLRQFPLTGTWPAPLEKPRAPMVSGQAVAITINKKDPPVSISPELKPKILLNTMAKANNKVVIENVEILETNLLNKNLPSKAVINTTIRSQPYQLKVDNNQELSMDDVQNMLEDMANELDEIPSPQKEVFPQQSPNKPKVLNKSSIRILNKGPAAPLEPRIATPQIKRDESGNVAIVTEILDPNTLVVQEDLVKNAEQVPTNVFPCPDCERSFPLQQLLDIHRLNHTRKRSFQCPDCDKSFFSKYDMAKHTFIHTGERPFKCSVCEKGFTRKALLHRHERTHTDIPKFICVYCERPFISRQEMEKHAQRHTKKRPFPCGVCGKSFAFKQGLERHEVIHQSNLPFPCQHCPRSFPTACKLARHLVAHAGKRVYPCKYCPKSYLLSHHLSRHLRTHKQATDDSSFTCSECRDTHTSYDSLIEHSQIHASMSLKCTLCREEIGDADGVETHMQLHRESERFACEFCDHIFLSQAQAQKHIEDDHVVEMVPYNNEDEGEGDNEGEGEGEVDSESDAEKDLKEEPTEDPKEIEIKEEFLEEFLDDKDDSDSSFSPTPMKRRKTSPAKGKSVEAPKGEKRQTRSQDRGKVNKVAPKKDVAVAAKQGRLLGKQGKWHKI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00477528;
90% Identity: iTF_00546142; iTF_00615082;
80% Identity: -