Deoh002292.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila eohydei
Gene Symbol
hang
Assembly
GCA_035045825.1
Location
JAWNOT010000036.1:872713-887452[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 18 0.37 25 5.6 1.0 3 23 510 531 509 531 0.93
2 18 1.1 73 4.1 3.2 3 22 638 657 636 657 0.89
3 18 0.0008 0.054 14.0 3.3 1 22 749 770 749 772 0.90
4 18 0.65 44 4.8 0.1 2 21 784 803 783 804 0.93
5 18 0.00092 0.063 13.8 0.2 2 23 931 953 930 953 0.95
6 18 0.0027 0.18 12.3 0.1 1 23 961 984 961 984 0.96
7 18 0.0002 0.014 15.8 0.2 2 23 1070 1091 1069 1091 0.97
8 18 0.00038 0.026 15.0 2.9 2 23 1188 1210 1187 1210 0.97
9 18 0.03 2 9.0 0.2 2 23 1219 1241 1218 1241 0.95
10 18 0.0016 0.11 13.0 0.1 1 23 1254 1277 1254 1277 0.97
11 18 0.00017 0.011 16.1 1.1 1 23 1318 1340 1318 1340 0.99
12 18 0.0026 0.18 12.4 0.9 1 23 1348 1371 1348 1371 0.96
13 18 0.09 6.2 7.5 0.4 2 19 1379 1396 1379 1397 0.94
14 18 3.5e-05 0.0024 18.2 0.4 3 23 1500 1520 1499 1520 0.98
15 18 0.0014 0.095 13.2 0.1 1 23 1555 1577 1555 1577 0.97
16 18 0.00079 0.054 14.0 0.6 2 23 1665 1687 1664 1687 0.93
17 18 0.0085 0.58 10.7 0.3 3 23 1743 1763 1743 1763 0.98
18 18 5e-05 0.0034 17.7 2.3 1 23 2244 2266 2244 2266 0.99

Sequence Information

Coding Sequence
ATGTGCGACGCTGTCGCAACTACTACAACGACGACATCAATCCCAGCAGCAGGATCAGGATCAGGAGGTGCTGCTGGCGATACCACATTGACAGCAATGGAGGAGCGTACGCGACAAAGTTGCTGTCGCCTGTGCATTGCGCCCGCCAGCGAATGCATTTCGATCATTAACAGTTATGCGGCCGATAAGGAACCGCTGGCCACTAAAATACACAACTGCGTAAATATCAAGatcaCGCCATTGGATCGTCTATCGCTGCATATTTGCCATGCCTGCATCAGCTATTTGAACTCTTGGCAGAGCTTTAAGAATCGCTGCCTTAGCTCACAGTCCAAGCAACGCCAATGGCTGGACAGCGATAAAAGCAAGCAGCAGACGCTTTTGGGATATTTGGATTTGAACAAAACAGAGAATGGCAGCTCCCTTGAACAGCACCAGCACGAATCGAATACTGACTCAGCAGCGATTGCAGCTGAAAAGGCGTCCGCCAACATTTTGGATGGCATACCTTCGTTGAAGAAACGCAAATCGTTAACAGTTTATGTGAGTCCcaagcaacagctacaacagcaacaacaacaacagcaacagcagcaacaacagcaacagcagcaagtgcaGCATGCAGCAAGAGCATCGAGCGCGGCGGCGGAATCACAGCAAACGCTGCAGACCCTTTTATTGCAGGTGCcctcaacagcagcattgGCAACGATGtcaacacagcagcagcaacagcaacagcgcaaatatcaacagcaacagcagcaacgtgTCAAGCAACATTACCACCAGCACCATcaacaaagccaacaacaacagcatcagcatcagcgcTTGAGTCGAATTCGTCAGCCAAGACGTCAGCAACAAGCGACAATGTCTGGTCAACGAATGGTAAAATTTAAGCCGAAATTGTATTTGCCATTGGATATATCGGTGCCACCGCTGCCACCGCTGTTGCCGACGCCTTCACAGCAGTCCGacactgttgctgctggtgctaaGTTGgcgccgttgcctttgccgttgccgctaCCACTTGATTTTAGCCAGAGTCAGTGTCAGCATCCGAATCCGAATGCGAGTCAGAGTCAGCAGAAACATGGCAGcgtgttgccgttgccattgccgccgTCGACGCCGTTGTTGCCGCCACTGCCAGCTGCAACAATGACCAGCAACGCCGCTGCCTCTAGCTCGGCCTCTGTCTCAGCTACAGCCgtagccgcagccgcagtcacGACTCCTCTGCTCATGCCGCCGCTGCCCGTCGTACCGATCAAGGATGAGCCCATTGATGATATGGACGATGACTTCCAAATGAAGTGTATAGATGAGTCCGATGATATGATGGATCCAACAATGTTCCTAGAGCGCTCCGAGCATGAGGGCGATGTTCCACTAATGACCTCCGACTATGATTACACGGCGCAACACGGCGTGACGGCGGTTGCGGCGGCGGCATCGCTGCCCGCAAGCGCGGTTGCAAACGTGGCCGCCGCTGGCGACTCAAAGGTGGCCAGCTGTCGGGCCTGCAGCTTGCAGTTCTCGACGCGCGCGAATGCCCGACGCCACGAACGCAATCTGCATCCGAATCTGTTTCAATTGTCGACAGATTCACCAAATAATACGCCCATCACAAAACCAACGCCGGCTTTAGCCGCCGCTCTGGAAATTCAACGTGccgcagcggcggcagcagccaccGCGGAAGCAACCAAAGCCGCCGCCGGTGGCAACATATCAGCGCAAAAGTATCGCCAGGTGGTAATGAATACGTTCATCAAATGCGAAAATGGCGGCTTCGACTACGACAATCCGGAACAGTATCAGCAGCTGCTCACACGCGACAAGGTGGAGTTCATACAAGAGAACAATGAGTTTCTGGAGCAATACCAGACGATGACGTGTCGCTGCTGCAATAAGTACTTCAACACCTACAAGAACTTTATGGCGCATGTGCGCAAAAAGTATCCGCTGCTGCCGCGCAATCTGTGCTTCAACTGCCTGAAGATGAACGACTCGAAAGCGCTGTTCATATCGCATCTGAAGAAGCGCAACTGCATCAATTTGTATCGCGTTCTCAACGCTTTGCGCTCGAAGCAGCCAAACTTTTCGCATGCCAGCGCATCTGGAGCGGTTGTCTCCGCCGATTTGAGCATTGGCCAGGCAGCGGCACACGAAACATCAACGGAGCGGCCCGAGAAGCTGCGTGCCAAGGAGCTGTTGGTTAACAAACTGTATGAGTGCAAGCTGTGCCCGAAGGGTTTTCGCACCAAGCACGAGTTCCGCACGCACGTGTACGACAAGCATGCGGATGTGCAGCGCAAGGATAACAATTCGATACAGTGCAGCTTCTGTGAACTGGACTTTGCCGATCCCGTCGATCGTCGTCGCCACTACAACAATATGGACTGCATTGTGCGGTTGCGCTGCATGACCTGCGATGCCAAGCTGGAGACGCATCAGCGCTTTCTCGATCACGTCTACCAGGATCACTTGGGCGGTGTGAGCAGCGATAATGCATCTACAGCTAACAGCGGCATGGATCATTCGCCCGGTAAACGCAGCCTGCTGGGCGCCTTGGGGATTGGTGTGAGCCAGTCATCGAATGATGAGTCACGTAGCAGCAttcataacaataacaatgcagTGGAATCGGCCTTCACCTCAACACCGAAACCAGCTGGAACAGCGGGCggcgcagctgcaacagcgaTCAGTGGTGGCTCCACGTCGGGCAGCCGCGATGCACCCAAATCGCAGTATTTCTCCCGCATGCCACAGGTGTGCCCCATTTGTGGCCAACAgtacaacaactacaacaacgtGCTGCGTCACATGGAGTCGAAGCATCCCAACAAACTGCCCGAGACATACAAGTGCGTGCGCTGCGGCCTGGGCTATCCGCGAATCTCCTATCTGCGCGAGCACATGATCAATGTGCACGGCGTGGACAAGAATCGACATTCGGGCGGCTTTGAATACATTGTGAATGCCGATGCAGTTAAATTGGCGGATGGCAGCACGCCGAACGTCTATACCGGGCGATATGATTATGTGATGAAGGATCTGATGTCAATAACAAATGGTGGGACACTcgatgatgaggaggaggagagCGGAAGCGTTGCCAAAAAGATGCGACtcgacgacagcagcaacaatagcagcatCAACATGAACATTGCCAATCAGCAGAAGGAGTGTCTCATCTGCAATGCGGTGTTTAGCAACAACATTGGCTTGTCGAATCATATGCGCTCGCATTATACAGCCTCGACGGCGACCAATGCAGCGCTGGCGGCTGCCAATCGCATGACACCCAAATCTTTGACAATTACTGCAGCTCCGTCACTGGACACGACtgcggcgtcgtcgtcgtccagcatggcagcagcaaatgcggcgccggcggcagcagcagcagcaactacaacaacagtcGTCACAGCCGGTGGCAGCTTGCCACCAGCGATGGTGCATCAGACGCCACAGGAACAGGCCGTGTTCCGGCGCAGCTTGGATCAGGCAGCCGATCGCCGCTTTCGACGCATGCGCTGTCGCATCTGCCAGCGCAGATTCAGTTCGAAGAAATCATATCGCTATCATATGCTCACCGACCATCAGGTGCAGAACGTGCAGTTCATCAAGTGCAAGCTGTGCAATGCCGAGTTTGCCTATGAGAAGGGCCTCAAGGTGCATCTGTTCAAGGTGCACGGACGTGCCATCAAGGACGAGATGATTATCAAGCAGTTCGAGTGCGATATCTGTTCGATTGTGTACAGCTCCGAGCTGGAGCTGCAACAGCACAAGCGCAGCGTTCACAAATCCCAAATGGGCGCCAACGATGCGTCCAAATCATCAACCAAATCATCTACCGCTACCTCAGCTGCTGACCTGGTCGACGCATCGGGCACGGCTGTGGCCGTTATGCCACTCTACTGGTACCAGTGCAAGTACTGCCCATCCAACTTCAATACCAACAAGAAACTGGCCATACACATCAATTCGCACGACGAGTTCGATTCGAACGATTATTCGTGCAAGGATTGCGGCAATGTCTACAGCGGACGCAAGAGCCTCTGGgTGCATCGGTATAAGAAGCATCCGCAGGTACCAGATCCGGCTGAGTGCACGCTGTGCCGCAAGATGTTCTTTGATCGCCAGATGCTGGAGAATCATACGCCCACCTGCAATCGGAAGCCCATCACTGCCACCGGCGCCCATCAGCAggatcagcagcaacagcaccagcagcagcaacaacaccagcagcaacagctgcaaatgcaacaacatcGCGCCATATTCAAGCATAAAACGGGCGATGAtgacgaggaggaggaggacgatcagcttttgctgctggACGATGGTGTCGTTGGCAGCGATAGCAACGGCGGCAATGTGATCCATGCGACggccacaagcagcagcaatccaAATACGATAAATGCGAGCACATTGAAGATACGCATACCGGAGGTGGCGTGCACCATTTGTGGTGCTCGATTCACTGACCAGGAGATGTTCACCAAGCACATACAGAAGCACGAACAGGATCTGTATGTGGACAATCCATTGGCGGCCATGTTCGACGATGGCCCAGCCGATGCTGGCCAATTTCAGGTGGAGCGGCAGAACGAGAATGGGGAATATGCGTGCGATTTGTGCACCAAGACGTTCCCCCAGGTGATTGCGCTCAAGGTGCATCGCAAGTGGCATTTCAGAGGTGATAGCAAGCAGaatccCATCATCGACGGCGAAGCGACAACgctgaacaacagcagcagcaacaacaacaacaacaacaattcgctGAGCTCCTCATTGATGCTGCGCGAGCTACATGCAGTGGGTCTGATGcccaaccagcagcagcaccagaaacaactgcaacagcagcaacaacagcagcagcaacaacagcaacggaaCAACACATCGAGCAGCTCGAGCAAGTCGATGAAGCGAAAACGTGAACTTAAATGCGAATACTGCGCCTCCACATtcattagcaacaacaacctgcGACGCCACATGTACGAGCTGCACAAGCACGAGGTCAGCAATCTGCCAGAGCCGCCAGTTATAGAAGTGGATGAGCCGCTAACGTGTCGTCGTTGCGGCGATATACGCTTCGATACCAAAGAGCTGTGGATCGAGCATAAGCTGGCGGACGCCAAAGTGGTTCGTCCGTTCTGTCCATTCCAATGGGGCTGTGATCTGTGCGGCGAGTACTTGTCGCGCAAAGAGAAGCTCATCAATCACATTAACAATCATCTCAAAGAGGATGTGATAGTGCCCGTGGCAACATTGGCGGCTGCCACCAAGGCGGCGCCACCAGTTTCCGTGCTGCCCAACAAgaatgcaacagcaaaaacggCAGctggaacagcaacaacagcagcaggaacagcaacagcaacgggaGTTGGGTCAAAGGGCATAATTAGAGCGGCGGCACCAGCTGGAAAAGTTAATAAGAGTAAACAACTGGAGGAGCTGACAATGAAGGTGGCtacaaaacagcagcagcagcaacagcaacagcagcagcagcagtcggcaAATGATGATAATGCTGAGCAAGATGATGAGGCGGACGATAGTGATatggatgatgatgatagcGATAGTGGCGATGGGGATAGCACGagtgctgatgatgatgatgaggacgacgacgatgatgacgatgaggGCGAAGTTGACGACGaagacgatgatgatgatgatgaagatgtgGATGGAGCTGTTGTcgaacaacaattgctgcaacaaaaacaacaacagcagcagcaacaacaacaacaacaacaaagccagCCCctcaatagcaacaacagcaatcacaGCAATAGCGTAGTTGCaaacgatgatgacgatgacctCATTGAGGAAGTCATCGAGGAAGATGGCATTGTCGAGGAGTTagacgacgatgatgacgacgatgaggatgaCGACGGGGACGACGATGGTCATACGACCGATGAGCATCAACAGCTGACAGCCAATGCAAAGCAGCAGACGAGACGCCTCAACTTTGACTACTCGCGCTCAGACAGCGCCAAGCTGAACGGCAATGGGAAAGCgacgccgcagcagcagcagcagcagcagcagctgacaaaGTCAAAGGGACAGCCGGCGGCGGTGCTGGTCATGCATAGTtccgaggaggaggaggatgaggatggtgttggtgttggtcatgtcgatgatgatgatgaggatgaggaggGCGTGGGTGAAGCGATGAACATTGATGATATTATTGAAGAAGATGATGGGGAGGATGATGACGATGTGGTTGGTGTCGGTGGCGGTGTTGttgaggatgatgatgatgatgacgatgatgatgttgaGGAAGATTTGGATGaggatgacgacgatgatgatgatgacgacgacgatgatgacgacgacgacgacgatgatggcGTCAAtattggcaacaacaatcgtCGTCGCGGCGGTGCTGTGATGGTCAGCGGCATCAGCATTGGCGACGGTGAGGCTGATGATggtgttgctgatgctgatggcGATGGTGATGGTGATGGTGATGCTGATGGTGATGTGGATGCTGATGCTACATCATCATCTGAGAGcgagtcaacaacaacaacatcgcaTTCAATTGGTGAGCGGCGTAAAAAATCAGTAGTTAAATCAGCGGCACATGGCGCTGCCGCTGATCAGTCTAATTCCACCTATACGTGTGATCTATGTCAACTTTGTTTCGATTCTCAGGAGCAACTGCAGTCACATATTAAAAGCCATTTTCTGAATGGGCCGTCGGCgggtggcagcagcggcagcagcgccagcaacagcggcaattGCAGAAGAATCGGTGTcagcgctggcagcagcagcggcggcaggacccacaacaataataagaatagtaataataataacaataataataataataataacaataataataacaataacagcaaaagcaaaaccaaaaagtcCGGCTTGGATGCAACGAAAGGTgacaatgctgctgctgctgcaacaacagcagcaacgacaacaacaacagcagcagcaacaacaacaacaacagcaacgacaacagcaacagttgccgctgaagcagctgcagcaacagcagctgcagacgcAGCCAGCAGCTTGAACTGA
Protein Sequence
MCDAVATTTTTTSIPAAGSGSGGAAGDTTLTAMEERTRQSCCRLCIAPASECISIINSYAADKEPLATKIHNCVNIKITPLDRLSLHICHACISYLNSWQSFKNRCLSSQSKQRQWLDSDKSKQQTLLGYLDLNKTENGSSLEQHQHESNTDSAAIAAEKASANILDGIPSLKKRKSLTVYVSPKQQLQQQQQQQQQQQQQQQQQVQHAARASSAAAESQQTLQTLLLQVPSTAALATMSTQQQQQQQRKYQQQQQQRVKQHYHQHHQQSQQQQHQHQRLSRIRQPRRQQQATMSGQRMVKFKPKLYLPLDISVPPLPPLLPTPSQQSDTVAAGAKLAPLPLPLPLPLDFSQSQCQHPNPNASQSQQKHGSVLPLPLPPSTPLLPPLPAATMTSNAAASSSASVSATAVAAAAVTTPLLMPPLPVVPIKDEPIDDMDDDFQMKCIDESDDMMDPTMFLERSEHEGDVPLMTSDYDYTAQHGVTAVAAAASLPASAVANVAAAGDSKVASCRACSLQFSTRANARRHERNLHPNLFQLSTDSPNNTPITKPTPALAAALEIQRAAAAAAATAEATKAAAGGNISAQKYRQVVMNTFIKCENGGFDYDNPEQYQQLLTRDKVEFIQENNEFLEQYQTMTCRCCNKYFNTYKNFMAHVRKKYPLLPRNLCFNCLKMNDSKALFISHLKKRNCINLYRVLNALRSKQPNFSHASASGAVVSADLSIGQAAAHETSTERPEKLRAKELLVNKLYECKLCPKGFRTKHEFRTHVYDKHADVQRKDNNSIQCSFCELDFADPVDRRRHYNNMDCIVRLRCMTCDAKLETHQRFLDHVYQDHLGGVSSDNASTANSGMDHSPGKRSLLGALGIGVSQSSNDESRSSIHNNNNAVESAFTSTPKPAGTAGGAAATAISGGSTSGSRDAPKSQYFSRMPQVCPICGQQYNNYNNVLRHMESKHPNKLPETYKCVRCGLGYPRISYLREHMINVHGVDKNRHSGGFEYIVNADAVKLADGSTPNVYTGRYDYVMKDLMSITNGGTLDDEEEESGSVAKKMRLDDSSNNSSINMNIANQQKECLICNAVFSNNIGLSNHMRSHYTASTATNAALAAANRMTPKSLTITAAPSLDTTAASSSSSMAAANAAPAAAAAATTTTVVTAGGSLPPAMVHQTPQEQAVFRRSLDQAADRRFRRMRCRICQRRFSSKKSYRYHMLTDHQVQNVQFIKCKLCNAEFAYEKGLKVHLFKVHGRAIKDEMIIKQFECDICSIVYSSELELQQHKRSVHKSQMGANDASKSSTKSSTATSAADLVDASGTAVAVMPLYWYQCKYCPSNFNTNKKLAIHINSHDEFDSNDYSCKDCGNVYSGRKSLWVHRYKKHPQVPDPAECTLCRKMFFDRQMLENHTPTCNRKPITATGAHQQDQQQQHQQQQQHQQQQLQMQQHRAIFKHKTGDDDEEEEDDQLLLLDDGVVGSDSNGGNVIHATATSSSNPNTINASTLKIRIPEVACTICGARFTDQEMFTKHIQKHEQDLYVDNPLAAMFDDGPADAGQFQVERQNENGEYACDLCTKTFPQVIALKVHRKWHFRGDSKQNPIIDGEATTLNNSSSNNNNNNNSLSSSLMLRELHAVGLMPNQQQHQKQLQQQQQQQQQQQQRNNTSSSSSKSMKRKRELKCEYCASTFISNNNLRRHMYELHKHEVSNLPEPPVIEVDEPLTCRRCGDIRFDTKELWIEHKLADAKVVRPFCPFQWGCDLCGEYLSRKEKLINHINNHLKEDVIVPVATLAAATKAAPPVSVLPNKNATAKTAAGTATTAAGTATATGVGSKGIIRAAAPAGKVNKSKQLEELTMKVATKQQQQQQQQQQQQSANDDNAEQDDEADDSDMDDDDSDSGDGDSTSADDDDEDDDDDDDEGEVDDEDDDDDDEDVDGAVVEQQLLQQKQQQQQQQQQQQQSQPLNSNNSNHSNSVVANDDDDDLIEEVIEEDGIVEELDDDDDDDEDDDGDDDGHTTDEHQQLTANAKQQTRRLNFDYSRSDSAKLNGNGKATPQQQQQQQQLTKSKGQPAAVLVMHSSEEEEDEDGVGVGHVDDDDEDEEGVGEAMNIDDIIEEDDGEDDDDVVGVGGGVVEDDDDDDDDDVEEDLDEDDDDDDDDDDDDDDDDDDDGVNIGNNNRRRGGAVMVSGISIGDGEADDGVADADGDGDGDGDADGDVDADATSSSESESTTTTSHSIGERRKKSVVKSAAHGAAADQSNSTYTCDLCQLCFDSQEQLQSHIKSHFLNGPSAGGSSGSSASNSGNCRRIGVSAGSSSGGRTHNNNKNSNNNNNNNNNNNNNNNNNSKSKTKKSGLDATKGDNAAAAATTAATTTTTAAATTTTTATTTATVAAEAAAATAAADAASSLN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00476771;
90% Identity
-
80% Identity
-