Deng000160.1
Basic Information
- Insect
- Drosophila engyochracea
- Gene Symbol
- -
- Assembly
- GCA_035042385.1
- Location
- JAWNLK010000014.1:773591-774550[-]
Transcription Factor Domain
- TF Family
- zf-LITAF-like
- Domain
- zf-LITAF-like domain
- PFAM
- PF10601
- TF Group
- Zinc-Coordinating Group
- Description
- Members of this family display a conserved zinc ribbon structure [3] with the motif C-XX-C- separated from the more C-terminal HX-C(P)X-C-X4-G-R motif by a variable region of usually 25-30 (hydrophobic) residues. Although it belongs to one of the zinc finger's fold groups (zinc ribbon), this particular domain was first identified in LPS-induced tumour necrosis alpha factor (LITAF) which is produced in mammalian cells after being challenged with lipopolysaccharide (LPS)[2]. The hydrophobic region probably inserts into the membrane rather than traversing it. Such an insertion brings together the N- and C-terminal C-XX-C motifs to form a compact Zn2+-binding structure [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 1 7.3e-08 7.1e-05 22.8 5.6 2 69 26 84 25 85 0.79
Sequence Information
- Coding Sequence
- ATGACCAACGTGGAGCCGCAAGTGATTTCCATTAGCATATCTAGCAGCAAGCCCAAAGTGGGCTACCTGAAAACTGAGTCCACCAGGGTCAATTGTCCCGCCTGCGAGCACTTCGAGATGAGTATTGTGGAACACGAGGTGGTCACTTCTCTGCAGTGGCTGCTGAGTTTAACCAAGCTATTCAAGAAGTGGTCTGGACGTGTGGATATCAATCATTATTGCGCTCACTGCGGCTGCTATATTGGACGCTATGTGCCCATTGGATGCTACGAGCGCTGTATATCAAACTCGGCACGAAAACAGGCAGTCGTGGATGACATGCGGCTAAAGACGAAACCAAAGGATTGCGCTGTGCGTGCACAAAAGTCGAGGGAAAACATACTGGCCAAACGGGCCGAGAAGCGTGCCCAGAAGCAGACACAAATTCAAACACATACGCAATGa
- Protein Sequence
- MTNVEPQVISISISSSKPKVGYLKTESTRVNCPACEHFEMSIVEHEVVTSLQWLLSLTKLFKKWSGRVDINHYCAHCGCYIGRYVPIGCYERCISNSARKQAVVDDMRLKTKPKDCAVRAQKSRENILAKRAEKRAQKQTQIQTHTQ
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00499266;
- 90% Identity
- iTF_00513858; iTF_00497825; iTF_00553442; iTF_00570786; iTF_00482662; iTF_00576742; iTF_00577447; iTF_00557577; iTF_00517387; iTF_00620267; iTF_00498545; iTF_00610321; iTF_00599261; iTF_00565056; iTF_00514570; iTF_00616587;
- 80% Identity
- -