Basic Information

Insect: Drosophila engyochracea
Gene Symbol: ush
Assembly: GCA_035042385.1
Location: JAWNLK010000105.1:10358336-10363736[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.051 3.2 8.3 0.0 1 20 217 236 217 238 0.89

2 9 0.0003 0.019 15.3 0.8 1 23 292 314 292 314 0.98

3 9 0.053 3.3 8.2 1.0 2 21 364 383 364 384 0.92

4 9 0.036 2.3 8.7 3.0 2 21 772 791 771 792 0.93

5 9 0.0095 0.6 10.6 0.0 3 21 842 860 840 861 0.91

6 9 0.02 1.2 9.6 0.0 2 23 931 952 930 952 0.98

7 9 0.004 0.25 11.7 1.3 1 23 958 980 958 980 0.99

8 9 0.0013 0.081 13.3 1.8 1 23 1047 1070 1047 1070 0.96

9 9 0.32 20 5.8 0.7 2 20 1180 1198 1179 1200 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.051	3.2	8.3	0.0	1	20	217	236	217	238	0.89
2	9	0.0003	0.019	15.3	0.8	1	23	292	314	292	314	0.98
3	9	0.053	3.3	8.2	1.0	2	21	364	383	364	384	0.92
4	9	0.036	2.3	8.7	3.0	2	21	772	791	771	792	0.93
5	9	0.0095	0.6	10.6	0.0	3	21	842	860	840	861	0.91
6	9	0.02	1.2	9.6	0.0	2	23	931	952	930	952	0.98
7	9	0.004	0.25	11.7	1.3	1	23	958	980	958	980	0.99
8	9	0.0013	0.081	13.3	1.8	1	23	1047	1070	1047	1070	0.96
9	9	0.32	20	5.8	0.7	2	20	1180	1198	1179	1200	0.91

Sequence Information

Coding Sequence: ATGGGGGAGAAGTGGGCGCGGTCAACGCGCATTGGCGGCCCGCACGAGAAGCAGacgaagcagaagaagcagaaactCGTGGAGCTTATCGGCGCCTTCATATCTATCGCAGCCATGTTCTATTCCAAAGAATTGGCCGCACACGAGCTGAGCGaggagaagcaacagcaacaccagcagcaccaacaacaacaacagcaacagctcgaGGATCAGGCCGAAGACGAGCAGTTAGAGCAACAGTCGAACAACTCCTCCTTGCAACCCGTCGAGACTGACATGGAACAGGAACTGGAGGAGGCGCAAGCGGCAGCCCAGGATTCCAGCGACCAGAAGTTGGCGGACAACCCGACCACGACAACGCCGCCGCGCAGCCCAACGCCTGGAGAACTGGTGCCAAAGCTGGAGAGAGCTGATACGCCCCCCTCAGTTCCAGTCACGCCCAGTCCACCACCGCGTACGCCCACACCACCGCCAATTGTACTGCCCAAGCTGCGACTCAATGCGTTGCTTGCCTCAGATCCGGCATTGAAGCCCGATGCCAAGGAGCTCAATTTGCACGAGTCACGACTGCTGGGTCCACCGCCCAAGCCGGAGCAGCAGCCAACTCTGCAGCCGGATGTGGAGCCCCTGTTGAAACCGGCGCGATTTATGTGCCTGCCGTGCAGCATCGCTTTCAGTTCACCATCAACGCTGGAGGCGCATCAGGCCTACTACTGCTCCCATCGCAACAAGGATGCTGAGGAGGAGACAAACGCTGCCGGTGATAAGGTGACATCCAACAGTGGTGGCACCTCCAATGCCAACAGCAGCTCCAGCGGTTCAACTGCCGGCTCCGAGCCACCCAACAAGGTGTCCCGCATTGGCAAACAATATGCGTGCACCCAGTGCTCCTACAGTGCCGACAAGAAGGTCTCCCTCAATCGACATATGCGCATGCATCAAACATCCCCAGCGGCACCCAGCCTAAACAGCCTCTCCAGCTTGACAGCAAAtggtgttgttgccgctgctgctgccgccgctgcggcggctgctgctgctgctggtgcgcAGCTCGACGAGAGCTCTAGTCAACAAATCGATCGCTACTGCAGCGACTGTGATATCCGCTTCAACAACATCAAGACCTACCGCGCCCACAAGCAGCACTACTGCAGCTCCCGTCGCAGCGACGGACATCTGACGCCCAAGCCGGAGGCGGGTGGCATCACTGGTACTgtagttggagttggagttggtggagctggtgctggaggtggtgctggtggaggtggagctgcatcagttgctgctgttgctgccggcaAGCATAGTCCACAGACGCGCAACAAGACGCCAACGCCAGCaatggttgctgctgccgccgccgctgctgcggctgctgctgcctcgcTGCAGGTGGCACCACCGCAACCCTTCCTGGCGCTGCCCACCAATCCGATTATCATAGTGCCCTGCTCGCTAATACGTGCTGCCAGCTTGATACCGGGACCACTCACCACTTCTACGTCGGGCATTGTGAATCCGGAGTCCACATGTTTCACGCTCGACAATGGCGCTCTGAAGCCTTTAGCCACGGCTCTAAACATAAATACGCTAGGAGGCAGTGCCACGCCTACGCCTACGCCTATGCCCAGCAGCAATCAGATACCGATGCCCGCTTTAGAGCCAGATCGTCCAACTCCTGTGAGCATTTCGAGCAACCTGGAAACGGAACCCAAGAAAAGTCCAGCAGAACCCAAGCGCAAGGAAACAAGCGGCATACGTGAGACGACGCCACTGGATTTATCGCTAAGACGCTCGCCAATCGCAGCGCTGTTGCAGCGCCAGCGTCTCGCGCGCTCTGCCGCTGCATTGCTCGACGCCGAGGATGCTGCAGGCAAGGATGCTCACTTGGAGAGCATCAGTGGCGGCAGCGTTACACCCGAGCAAATTGTTTGCGCTCCCTCGCTGCCCAGCAGCCCCTCGATGAGTCCCTCACCCAAGCGACGTGCTTTAAGTCCACGCAGCTCTGGAGCTGGCAGCGCTTCATCGATGTCACCGCCAGCCCATCATATGCTGGATAATTTGCCGCCATTGCGCTCCATGCTGCCTTCCGATTTTAATCTTTCCGAATCGCTGCTGGCAAAAACGAATCCAGAGTTGGCCCTCAAACTggctgcggcagcagcggctgctgtaGCTGGAAGTGGCTCGGCGGAGCTGGCCAAACTAGGATTTCCAGGAGCTGGTACAGCACCCAGCAGTAGTGCTGCTGCACCATCCTCTGCACAGAATGCACCGCAGATCTATGTGAAGCAGGGCGTCTCCAAGTGCAAGGACTGCAACATTGTGTTCTGCAAATATGAGAATTACTTGGCGCACAAGCAACATTATTGCTCGGCACGCAACCAGGAGACGGGTCTGGATGGAGATGCCTCCAAAAGCGCTGTAACGCCTCCCAGTGGACTATCATCAGTTGGCGGTAATGCTGGCGCCTCCTCTGCAGAAACCACTCCCGTTGCCTATCAGCAACTAATATGCGCCGCCTGCGGCATTAAATACACCTCGCTGGACAATTTGCGTGCGCATCAGAATTACTACTGTCTGAAAGGaggcgctgcagcagctgccacaccaGCTGaggcagcaccagcaccacaacTGCCACTCGCCCATCCCAAGGAGAAGTGCCCGAAATGCAAGACTCATCATGAGCACGGACAGAATTGTCCACCACCCCCACCACCATCAACTCCACAACTGCCTGCTCCCTGCTCCACCTCTGCCACGTCGAATAGTGTCAATAAATGTCCCGTTTGTGGCGTAATTAGTCCCACTGCTGCTCTCGCCCGCAAGCACATGGAGATGCATGGAACGGTAAAGGCTTTTCGCTGCTCCATTTGCCAGTATAAAGGGAACACTCTCCGCGGGATGCGCACCCACATTCGCACCCATTTCGATAAGAAGACCAGCGATGTGAACGAGGAGCACTACATGACATGCATCTTTGAGGAGGATGCTGCAGCggtggcagctgcagttgctgctccaACTCAATCCTTGAATCTAGATCTGCCcgctgtggcagcagcggcggcggcagcagcagcagcagcagctcaagaGCAACTGGAACAGCACCCGGCACAGCTCTTCAATTGCGATCATTGCAATTATGCCTCATCCTACAAGGGCAATGTGCTGCGTCACATGAAATTACTGCATCCACATGTGGCCATTAGTTCGCCCTCAATTTCACCCGAGTCGCGCGAACATGAAGCCAATCCACACGCCCTACCCGAAGTAGCGCTAGTTAATGGGGAACGGGAGGCAGCAGCTGTGCCCAGCTTCCACATTAAAACGGAGGCATTGGAGGCACCGGTGGCCACATTGAGTCTGGTGCATGAGAACAACAATTCACCTATTGGCACGCCACTTACCCACATTAAAGCGGAGCCCATGGAACTTGGAGTAGATGTATCAGTACCATCGCTACCCCCACCGATGGCCAATTCCCCGCTTGGGCCGAGCGCAGCGGAGGCATTGAAAAAATACTGCTCCACCTGCGACATATCCTTCAACTATGTGAAAACATTTCTGGCGCACAAGCAATTCTACTGCAAGAGCAAACCGCATCGACCCGAGGCAAATGATAGCCCCAGTCCCACGGTGGGTGGTGGCGTCTCAATGCCGCTGCAGTCGCCCAgcgagctgctgttgctccagAAGAACAAGGAGAATCTGCAGGAGGCGGCCATTTGA
Protein Sequence: MGEKWARSTRIGGPHEKQTKQKKQKLVELIGAFISIAAMFYSKELAAHELSEEKQQQHQQHQQQQQQQLEDQAEDEQLEQQSNNSSLQPVETDMEQELEEAQAAAQDSSDQKLADNPTTTTPPRSPTPGELVPKLERADTPPSVPVTPSPPPRTPTPPPIVLPKLRLNALLASDPALKPDAKELNLHESRLLGPPPKPEQQPTLQPDVEPLLKPARFMCLPCSIAFSSPSTLEAHQAYYCSHRNKDAEEETNAAGDKVTSNSGGTSNANSSSSGSTAGSEPPNKVSRIGKQYACTQCSYSADKKVSLNRHMRMHQTSPAAPSLNSLSSLTANGVVAAAAAAAAAAAAAAGAQLDESSSQQIDRYCSDCDIRFNNIKTYRAHKQHYCSSRRSDGHLTPKPEAGGITGTVVGVGVGGAGAGGGAGGGGAASVAAVAAGKHSPQTRNKTPTPAMVAAAAAAAAAAAASLQVAPPQPFLALPTNPIIIVPCSLIRAASLIPGPLTTSTSGIVNPESTCFTLDNGALKPLATALNINTLGGSATPTPTPMPSSNQIPMPALEPDRPTPVSISSNLETEPKKSPAEPKRKETSGIRETTPLDLSLRRSPIAALLQRQRLARSAAALLDAEDAAGKDAHLESISGGSVTPEQIVCAPSLPSSPSMSPSPKRRALSPRSSGAGSASSMSPPAHHMLDNLPPLRSMLPSDFNLSESLLAKTNPELALKLAAAAAAAVAGSGSAELAKLGFPGAGTAPSSSAAAPSSAQNAPQIYVKQGVSKCKDCNIVFCKYENYLAHKQHYCSARNQETGLDGDASKSAVTPPSGLSSVGGNAGASSAETTPVAYQQLICAACGIKYTSLDNLRAHQNYYCLKGGAAAAATPAEAAPAPQLPLAHPKEKCPKCKTHHEHGQNCPPPPPPSTPQLPAPCSTSATSNSVNKCPVCGVISPTAALARKHMEMHGTVKAFRCSICQYKGNTLRGMRTHIRTHFDKKTSDVNEEHYMTCIFEEDAAAVAAAVAAPTQSLNLDLPAVAAAAAAAAAAAAQEQLEQHPAQLFNCDHCNYASSYKGNVLRHMKLLHPHVAISSPSISPESREHEANPHALPEVALVNGEREAAAVPSFHIKTEALEAPVATLSLVHENNNSPIGTPLTHIKAEPMELGVDVSVPSLPPPMANSPLGPSAAEALKKYCSTCDISFNYVKTFLAHKQFYCKSKPHRPEANDSPSPTVGGGVSMPLQSPSELLLLQKNKENLQEAAI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00538480;
90% Identity: iTF_00570666;
80% Identity: -