Basic Information

Insect: Drosophila engyochracea
Gene Symbol: Znf574
Assembly: GCA_035042385.1
Location: JAWNLK010000107.1:4861855-4864125[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 2.7 1.7e+02 2.8 2.6 2 23 332 354 331 354 0.94

2 10 0.059 3.7 8.1 0.1 6 23 364 381 364 381 0.98

3 10 4.9e-05 0.0031 17.8 4.4 1 23 387 409 387 409 0.98

4 10 0.00038 0.024 15.0 1.0 1 23 415 438 415 438 0.93

5 10 0.00024 0.015 15.6 2.8 1 23 446 469 446 469 0.97

6 10 0.16 10 6.7 0.4 3 23 477 498 475 498 0.92

7 10 0.5 31 5.2 0.2 2 23 510 532 509 532 0.93

8 10 0.0028 0.18 12.2 4.1 1 23 539 562 539 562 0.93

9 10 3.5e-06 0.00022 21.4 3.7 1 23 568 590 568 590 0.98

10 10 0.04 2.6 8.6 3.3 1 23 596 619 596 619 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	2.7	1.7e+02	2.8	2.6	2	23	332	354	331	354	0.94
2	10	0.059	3.7	8.1	0.1	6	23	364	381	364	381	0.98
3	10	4.9e-05	0.0031	17.8	4.4	1	23	387	409	387	409	0.98
4	10	0.00038	0.024	15.0	1.0	1	23	415	438	415	438	0.93
5	10	0.00024	0.015	15.6	2.8	1	23	446	469	446	469	0.97
6	10	0.16	10	6.7	0.4	3	23	477	498	475	498	0.92
7	10	0.5	31	5.2	0.2	2	23	510	532	509	532	0.93
8	10	0.0028	0.18	12.2	4.1	1	23	539	562	539	562	0.93
9	10	3.5e-06	0.00022	21.4	3.7	1	23	568	590	568	590	0.98
10	10	0.04	2.6	8.6	3.3	1	23	596	619	596	619	0.97

Sequence Information

Coding Sequence: ATGGATGTACCAGTGCCTGAGGCATGCGTGCTGTGCCTGGAGGAGAATGCCCTCACCCTGAACGGCTATTTGGACATCTACTCGACGGAGGGCGCACAACTGAATGTGGTGCAGATAATCAACAAGCATTTTCCCATGCAGCTGGATGCAAGCAGGGGAGGTGCACGAAAGATATGTTCACACTGCTGGGGCACTGTGTCCGCATTCAATGCGCTGCACGAATTTGTCAGCGCCGCACAGAGTTCGCTGCAGGACGCGAAGGTGCTGCCCATGGAGGATGATCCCTTGACGCAGGGCAACTTCAGCGAGGCACCCAAACAGAATCAGGAGCAAGTCGAACAGAACGGTCGCAATTTCTTCTATCCCGAGGTTAAGATTGAGGAGCATGAGCTGGAACAGCTGCCAAAAATAGAGGTGCTCGAAAGCACGACAAGACCGCAAACGGCGGAGGTTGATGCATCTCCGGTGAGACGATTGCGCAAGCGCGTCAAGGCCGAAGCTGAAGCACCAACTGTGGAGGCGTGTGAAGATAGCAATCAGGATTCAACCATACCCACTGAGGCGCCGAAAAAGCGTCGCGGGCGACCGCGTAAAATAGACTTAATCCTCAAGGACTCGCCAAATGTCACGCAAGCTGAACCAACTGTTGACTTAGATGCAGATTTAAAAGCAGAACCACTTGCCGATCTTAGCGATGATGATCAGGATCAGGATTTCTCCAGCCAACTCGATGATGGTGTTGCGCGCAGCGAGGATAGCAGCGATGAGGAGAGTTCAGAGAGCGATGACGATTCCGATTTTACGGCGGACAAGCCCAGCGAAAGCGATTTCGCTGTCATACCGAAGCGGACGACAGTGCGGCCCAAGAAATACAAGAAGCGTACGAAGCCGGCGGAGCCGAAAGTCCGCAAATCTCGcgagcagcaggaacagcgcAAGAAGCAACAAGAGGAATTCGATGGCATCATTGCCAAGTTCTTTAACGATGTGTTGCCGTGCTCCATTTGCAATCTGTTGGTCCATAATTTTACGGAAATGCAACGACATCATCGTCTCACACATCAGGTAGATCCGGGCTATGTGATTTGCTGCGGCCGGAAGTTCACGCAGCGCAAGGTGCTTGCCGAGCACGTGCTGGTGCACTGGAATCCGGATCACTTCAAGTGCAGAACCTGCGAGAAATCATTCCAAAACTCACGACATCTGGAGTCGCATCAGCAGATACACATGGCCAAGCTCTCCTTCCAATGCGAAATATGCTCAAAGGTCTTCACCAGCAAAACGGCCATCGAGTACCATAAGCTGAACAAACATGTGCCCAAATCCGAATTCAAATTCACGTGCACAGAGTGCAATAAAAAATTCCTGACCGAACGCAAGCTGAAGAATCACATGAACTCCATGCACGATCCAGAACGGATAATCATATGCGACAAGTGCGGCAAACAGATGCGCAccaaaatcattttgaaaaagCATCAGGAGCTCATGCATTCGGACACGCCGCGACCGGAGCCAGAGTTGAAGCAGTGCCAGATCTGTGGTGCCTGGCTGAAAGGCATGACCGGTCTGAAGCAGCACATGAAGAGCATTCACGTGGAAAGCGCCGGCGAGCATCGTTGTCATGTGTGCAGCAAGGTTTCACCGAATGCCCGCGCTCTGCGTCGCCATATTTATCACAATCACGAATGCGAGCGCAAGTTCAAGTGTACCATGTGCCATAAGGCATTTAAGCGACCCCAAGAACTAAAGGAGCACACATCCACGCACACCGGCGAGGTTCTATATACGTGTCCAAACTGTCCGATGACGTTCTTCTGCAGCGCCAACATGTATAAGCATCGGCAGCGTTTGCATCGGGCACAGTACGAGGCGGACAAGAATCAGCCAAAGCCACCCAATATTCTGCAGCAGGCAGTGGGTGCCACAGCCGCCATGAAGATGCAACGCATTCAGCACACGACTGTGGCCAGCATAGAATCGGACTTGAAGCATTTTTAG
Protein Sequence: MDVPVPEACVLCLEENALTLNGYLDIYSTEGAQLNVVQIINKHFPMQLDASRGGARKICSHCWGTVSAFNALHEFVSAAQSSLQDAKVLPMEDDPLTQGNFSEAPKQNQEQVEQNGRNFFYPEVKIEEHELEQLPKIEVLESTTRPQTAEVDASPVRRLRKRVKAEAEAPTVEACEDSNQDSTIPTEAPKKRRGRPRKIDLILKDSPNVTQAEPTVDLDADLKAEPLADLSDDDQDQDFSSQLDDGVARSEDSSDEESSESDDDSDFTADKPSESDFAVIPKRTTVRPKKYKKRTKPAEPKVRKSREQQEQRKKQQEEFDGIIAKFFNDVLPCSICNLLVHNFTEMQRHHRLTHQVDPGYVICCGRKFTQRKVLAEHVLVHWNPDHFKCRTCEKSFQNSRHLESHQQIHMAKLSFQCEICSKVFTSKTAIEYHKLNKHVPKSEFKFTCTECNKKFLTERKLKNHMNSMHDPERIIICDKCGKQMRTKIILKKHQELMHSDTPRPEPELKQCQICGAWLKGMTGLKQHMKSIHVESAGEHRCHVCSKVSPNARALRRHIYHNHECERKFKCTMCHKAFKRPQELKEHTSTHTGEVLYTCPNCPMTFFCSANMYKHRQRLHRAQYEADKNQPKPPNILQQAVGATAAMKMQRIQHTTVASIESDLKHF

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00560591;
90% Identity: iTF_00560591;
80% Identity: -