Basic Information

Insect: Drosophila engyochracea
Gene Symbol: -
Assembly: GCA_035042385.1
Location: JAWNLK010000100.1:1963714-1967346[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.14 8.6 6.9 0.0 1 13 344 356 344 364 0.81

2 8 8.5e-05 0.0054 17.0 2.1 1 23 709 732 709 732 0.96

3 8 0.00086 0.054 13.9 3.4 1 23 761 783 761 783 0.97

4 8 0.00011 0.0068 16.7 6.5 1 23 789 811 789 811 0.97

5 8 3.8e-05 0.0024 18.1 0.9 1 23 817 839 817 839 0.98

6 8 0.00061 0.038 14.3 1.4 1 23 845 867 845 867 0.98

7 8 0.011 0.71 10.3 0.0 2 23 874 895 873 895 0.96

8 8 0.017 1.1 9.8 0.1 3 21 903 921 901 922 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.14	8.6	6.9	0.0	1	13	344	356	344	364	0.81
2	8	8.5e-05	0.0054	17.0	2.1	1	23	709	732	709	732	0.96
3	8	0.00086	0.054	13.9	3.4	1	23	761	783	761	783	0.97
4	8	0.00011	0.0068	16.7	6.5	1	23	789	811	789	811	0.97
5	8	3.8e-05	0.0024	18.1	0.9	1	23	817	839	817	839	0.98
6	8	0.00061	0.038	14.3	1.4	1	23	845	867	845	867	0.98
7	8	0.011	0.71	10.3	0.0	2	23	874	895	873	895	0.96
8	8	0.017	1.1	9.8	0.1	3	21	903	921	901	922	0.91

Sequence Information

Coding Sequence: ATGACGCCAGCAGCTGTTGAGGATGGGCGTGAAAAATGCGGCAGCGTCTACACTTGGAACTGTGCTGGCGAACTCTATGGCATCGAGTGTGAGCTGTGCGAGGAGCGACCCCTTTGTGCACTCGATGAGTTTGCCGAGCATATGGAGCTGTGGCACTCCGACTGGCAACAGGCACCGGAGGATGAGCTCATGCAGGAGGTCCTCGCCGAACAGTCCAGCAGCAACTGCGAGGTCAATGAACTCAAACAGCAGCTGGTTCAAGAGCTCAACTCGCTCGATAAACagacacagcagcaaccacagctgATGGACACATATCAACTGAACGATCAAGTTCAGTTCAATGCGGATagtGGCCTGCCCAGTGTGGAATCGGCAGCGAAGTTGACGACGGAGCATGTGCAGCAGCTGATTGAGCTGTATCGATCGCATCCGCGTCTGTGGGATCAATCGCATCTAGAGTTTCGGGACGTGGAGCAGTGTCGCCACTCGTGGCGCCAGATAACGGATGCGTGGAGTGCCCACTGTGGACGTGGTTTCAGTGTGACCGATGTGCGCATCCGGATCTCAACGCTGTGCCAGCGATTCCTCAAGCAGCGTGAACGCATCGATGCCGAGGGTGATCTCGATGAGGGCGCCAAATTCGTCCATTACGATCAGTTGCGCTTCCTCTGTGAGCAGCAGGCGCTGCTGAAGCGCCAGGAGCACTTTGCCCGCGAGAATCGCAAACTGCTCGAGATCTACGAGCATTATCCAATACTCTGGCACAATGCCCACAAGAGATTGCGCTGTGCCGCAACGGTGAAGAGGCGCCAGGAGGCACATCGTGGCCTCCAGCTGGCGTTACGTATGTGCGGCATCAATCTGTCCGGCTTGGCGATGCAGCGGCGACTCCAGTCGCTGAGGAAACGCTATCGACTGGAGAAGATACGCTATCTGCACAGTGTCGTCGAGGGCAAACAATCGGAATTTGTGTCCATCTTTGAGCATTATGCCGAAATGGAGTTTCTGCACAAGCACATCGATCCCTATGTCTGTGCTGGTTGCGGCAAGATCTTTGAGAATCTGATCGGTCATCAGGCGCATGTGCAGGATAGCTGCGAGGAGCAATCACTTGCTGCCGCCGACTGCAAACAGTTGACCGAATCGGAGGCGACGCTGGGCGAGCTTATGGTGCAGCTCGAGCAGCACGaattacagcagcagcagcagcaacagcaacaccagcagcagtctGCCGGAGAAAAACCCGAGCAGCTGCAGGTAGTGGAGCGAgtggaacagcagcaggagcagctggtggcagcagcaactacaactgaGCTAGCCACACCACTGCTACATAGTCTAGCAGAACAGGAGGATGCGCAGCAGGCGGAGATTGAGCAATATCCTGACAAGGAAGATCCGCACGGCAAAGAGTCCTTCTCCGAGGATAGCCTGTCGACGGGCGGACAGCTACGGATGCGCCTCAGCCTGGAGCTGACCAATAAACTGATTGAGCTATATCAATCGCATCCAAATCTCTGGGATCCCAATCATCTGGACTATCATGCGAGGAAACAGCGACGCCAGGCCTGGCACAACATTGCCGCCCAGCTGAACACATTCGCCGGCTGTCCGGATCGCTTTAGCTGGCAGATGTTGCATCGCAAGCTCACCGATTATGTCAAGTACTATCGACGCGAACGCCAACGAGAGGAACTGGCGGTTGGAGGTGGTGGCGAGGGCACACGTTGGGGCTTCTACGAGGCGTTCAGCTTTATGGACGATGTGGTGCCCATAAATCGTGTGCTGCAGAAATCGTTGCAGCAGCGCGACAGCAATCTGAAGATTATCCAGGTGTATCAGAGCTACGAGCAGCTGTGGTGCACCACACATCCGGATTATACAAAACGTAAGCAGCGCTTGCGTCACCTGGAATCGCTGTGCACCCGCCTGCAGGAGGAGTGCAATCTGCAGATAACCGTTGAGCGTTTGAAGAGTCGTCTGATCGAGTTTCGCTGCCAGTATCGTCAGTGCAAGGAGGCACGCCAGGCGGCGCTGCAGCGCAACAATACCAACTGGCAGCCGACCTATGAGTATTATGCGGCGTTGCAGTTTCTCGAACTGCACGTGTCGCCATTCAACTGCGAACGGTGCACGGCGAGCTTTAAGCGCCGCAGCGATTATCTGCGGCATCAACGCAACGTTCACTTGAACCAGCAGCTGAATGAGATGCAGCCGTTGCAGCGACGCCGTCGCATGCGGCGTGGCACGAATGCGACAAATCCGCTCGAGCACATCTGTCACATTTGCGCAATGAAATTCTCGTTGCGCACCAGCCTCCAGGCGCATCTCCGTCGCCATTTGGGTCAGCGGACACACTGTTGCACCGACTGCCCCAAGAAGTTCTTCAATTCGACATCGTTGCGGGTGCATCAGCGAAGCCATACCAAAGAGCTGCCGTATGTGTGCGAGCATTGTGCCAGGGGCTTTGTCAACGCCAGCAAACTGAATCAGCATGTTAAGCGGCATACGGAGAAACGGGATTATCCGTGCACGCGCTGCGACAAGGCGTTCTACACGGCCCACGAGCGAGATCGCCACTTGCGCGCCCACCTCAACATTAGAGACAAGGTGTGTCCGTATTGCAGTCGGGCCTTTGTCGTTGGCAGCGCCTATTATGCCCATCTTAATTTGCATCGGGGCGAGAAGCGTTATGGTTGTGCTGCATGTGGCAAGCGATTCGCTCAATATGCGGGTCTCTATAAGCATCGCAAGCGCTGCACAATCGCCCAGCTGCAGGAGAAGTGa
Protein Sequence: MTPAAVEDGREKCGSVYTWNCAGELYGIECELCEERPLCALDEFAEHMELWHSDWQQAPEDELMQEVLAEQSSSNCEVNELKQQLVQELNSLDKQTQQQPQLMDTYQLNDQVQFNADSGLPSVESAAKLTTEHVQQLIELYRSHPRLWDQSHLEFRDVEQCRHSWRQITDAWSAHCGRGFSVTDVRIRISTLCQRFLKQRERIDAEGDLDEGAKFVHYDQLRFLCEQQALLKRQEHFARENRKLLEIYEHYPILWHNAHKRLRCAATVKRRQEAHRGLQLALRMCGINLSGLAMQRRLQSLRKRYRLEKIRYLHSVVEGKQSEFVSIFEHYAEMEFLHKHIDPYVCAGCGKIFENLIGHQAHVQDSCEEQSLAAADCKQLTESEATLGELMVQLEQHELQQQQQQQQHQQQSAGEKPEQLQVVERVEQQQEQLVAAATTTELATPLLHSLAEQEDAQQAEIEQYPDKEDPHGKESFSEDSLSTGGQLRMRLSLELTNKLIELYQSHPNLWDPNHLDYHARKQRRQAWHNIAAQLNTFAGCPDRFSWQMLHRKLTDYVKYYRRERQREELAVGGGGEGTRWGFYEAFSFMDDVVPINRVLQKSLQQRDSNLKIIQVYQSYEQLWCTTHPDYTKRKQRLRHLESLCTRLQEECNLQITVERLKSRLIEFRCQYRQCKEARQAALQRNNTNWQPTYEYYAALQFLELHVSPFNCERCTASFKRRSDYLRHQRNVHLNQQLNEMQPLQRRRRMRRGTNATNPLEHICHICAMKFSLRTSLQAHLRRHLGQRTHCCTDCPKKFFNSTSLRVHQRSHTKELPYVCEHCARGFVNASKLNQHVKRHTEKRDYPCTRCDKAFYTAHERDRHLRAHLNIRDKVCPYCSRAFVVGSAYYAHLNLHRGEKRYGCAACGKRFAQYAGLYKHRKRCTIAQLQEK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01322149;
90% Identity: iTF_00499824;
80% Identity: -