Deng012842.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila engyochracea
Gene Symbol
RREB1
Assembly
GCA_035042385.1
Location
JAWNLK010000167.1:5538749-5545683[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 13 0.036 2.3 8.7 0.8 1 21 265 285 265 287 0.93
2 13 0.00034 0.021 15.1 0.2 1 23 297 319 297 319 0.98
3 13 0.00025 0.016 15.5 7.2 1 23 325 347 325 347 0.98
4 13 0.07 4.4 7.8 1.8 2 20 574 592 574 594 0.93
5 13 0.016 1 9.9 0.2 1 23 742 764 742 764 0.97
6 13 1.2e-05 0.00079 19.6 0.7 1 23 774 796 774 796 0.99
7 13 0.00084 0.053 13.9 2.0 1 23 802 825 802 825 0.97
8 13 0.003 0.19 12.1 2.0 1 23 1102 1125 1102 1125 0.95
9 13 8.7e-05 0.0055 17.0 0.3 2 23 1520 1541 1519 1541 0.97
10 13 0.15 9.3 6.8 6.3 1 23 1547 1570 1547 1570 0.97
11 13 9.5 6e+02 1.1 3.4 1 23 1688 1711 1688 1711 0.78
12 13 0.0085 0.54 10.7 0.5 3 23 1774 1794 1772 1794 0.96
13 13 0.0014 0.086 13.2 4.8 1 23 1800 1822 1800 1822 0.99

Sequence Information

Coding Sequence
ATGCTcgccacacagcagcagcagcaacagcagcaacaacaacaacagcaacaagcaactgcagcatcagcagcaacacatgAGGATGCTCGGGATTTGGAGTTAATGGAGACGCGACAACGTCGCGATTCGAGCACCTCAGAATCCTCGCTGGAGCATTTGGACTTGGGTCGCACGCCCAAaaagttgagcagcagcagcggcgcacCGCAGCCGACGTCGACGCCGCACGACACAGCAGTGACAGCGACGTCGCGCAAGCGCAAACTGCGAcagcaacaccaccagcagcagcaacagttgccactcTCCGatgaggagcaacagcagcaacagcaacagcagcagcagctgttggaCTCATCAGCGCAGCGACCGCGTCACAAGCAGCGACGCGGCggcgttgctgccgctgccagcgCCAGCATCGTTGTCGACTACAGCGCCAGCGGCGACGCCAGTTCGCTGCGCAAAAAGTTTCGACTGAAtcgcagcagcgccagcagcaatgCCGCCAACGGTGATTTATCCGAATCGGGCTTCGTTGATGGCAGCGCCCTCAGTGGCTATCTgcttggcagcaacaacaacaacaacaacaacaataataataacaacaacaacaacaacaatatcagtaatagtagcagtagcagcgcaGTCGctcagtcagcagcagcagcagcgtcggcAGCGCAGCATGCGCCAAGCGTTAGCAGCTCGGGTGGCTCCTCGCCACAGGGCCTCTCGAGCGCCGAGTCGGGCATCGGTGCCGGTGATGAGCACATGAAATATCTGTGCCCCATTTGCGAGGTCGTCTCGGCCACGCCCCACGAATTCACCAATCACATTCGCTGCCACAACTACGCCAACGGCGACACCGAGAACTTCACCTGCCGCATCTGCTCCAAGGTGCTGTCGTCGGCATCCTCGCTGGACCGGCATGTCCTGGTGCACACTGGAGAGCGTCCGTTCAACTGTCGCTATTGCCACTTGAACTTCACAACCAATGGGAACATGCACCGACACATGCGCACCCACAAGCAACATCAggcgtcgcagcagcagcagcaacagcagcagcagcactcgcaacagcagcagtccacacaacagcagcaacaggcacagtcgcagcaacaacagcagcagcgacgccagcaaCATGCAggtggagctggagcagctggtTCGGTATCGGGATCAGCACAGTTGTTGACGACGCGAGCGGAGAGCTATGAGAGTGATGCCAGCTGCTCGACGGATGTGTCCAGTGAGCTGAAcagtcacagcagcaacagcaatcagtccaaccacaacaacaataacaacaacaacaatagccacaaaacgaacaacaacaacaacaatgaggaTGAGCTCGAGCTGGACGATGAGCAGCTAGTTCTGAGCAGCAAACAGCGACGCCACAAGGCAGccctaaacaacaacaatataattaGGGATGAGGAGCACGATAATCGGCCGGATGATGATTCAGATGTGGACAGCGCTGATAGCGTTGCCCAGGTGATAACAAGCACACCGGATGTGGCCACGCTGCTCGCCTCGGGCGGCACCTCGCCCACCCACTCGCATTCGGAATCGCATTcaccgccgctgctgctgcagagcTGCCCGGCCTGCAATTCGGGTGAATTTGAATCTGTGCCAGCGTTGTGCGCCCATCTGGATGCCGAGCATGCTGACATACCGGCCAAGTGTCGCGAGTGTGATGTGATCTTTGCCACACATCGGCAGCTGCAGGCGCACAGCTGTCGAGGACTGCCGCCGCTGCTTGGTGTGAGCTCATCGCCACTGCACAAGCAGGAGGAGAGCGAACTGGaggagcagcaccagcagcagcagcagcacgaggAGGACcacgaacagcagcagcacaagcaagaggaacaggagcaggctGAACAGCGCGAATGCGAAGATTTCTTCCAGCAGCTGTATCTGAAGAATAAATCGTCAGCAACGCTGCTTCCCTCACCGATCAAACATGAGCCGGCGGATCAGCGACAGGATCTGGCCGATATTCAAAGCATACTCAACATGACCAATTCCAGCTGCACCTCGAGTTTCCTGCGCAATTTCGAGCAATCGGTGAACACGCCCTGCTCCAGCCAATATAGCGTCGATGGCCGCGATGGCGAGGAGGAGGCTCAGGATGCCTTCACCAATGAATTCCGCCGCATGAAACTGCGCGGTGAGTTCCCCTGCAAGCTGTGCACCGCCGTCTTTCCCAATCTGCGGGCACTAAAGGGCCACAATCGCTACCATCTGTCGGAGGTGGGCGCCGCCGGTCCATTCCGTTGCAACATGTGTCCCTATGCCGTCTGCGACAAGGCGGCGCTCGTGCGGCACATGCGCACCCACAACGGTGATCGGCCCTACGAGTGCGCCGTCTGCAATTATGCGTTCACCACCAAGGCGAACTGTGAGCGGCATTTGCGCAATCGACATGGCAAGACCAGTCGCGAGGATGTGAAACGTGCGATTGTCTATCATCCGGCCGAGGATGCCAGCTGCGAGGAGAACAAATCGCGGACCGAGGCCGATATCCTGACGGAGTTGAGCGGCTATCGTTGTGCAACACCCACGGAGCACAGCTCATCGGCTAGCTCCTCGTCACAGCTGAAGCACATGTTGCTGGCGGAGCCGACGCCGGCCGTAAAGgtagctgcaacaacagctgcagcagcagcagcagcagcagcaacaacaacaacatcgctGCCACAACAACCGCTCAAGATACAGGTGAAGAGCTTGGATCAGCTGGTGGATAAGCCACTGCCGGCACTCGATCTCAGCATGGATGCGCTCGACCTGAGCAAGAAGCCCGCCCAGCTGCTGGCCGAGCAACGGGAGCAAAGGGAGCAGCTCGAAAGACAcgaattgctgctgcagcagcagcaacagcaccagcaacaacaacagcagcagcagcaacaacaattgtttggGGCTGGCGATGCAGCTGCTCAGTATATGCAACAGCTGTTGCGCAGCTTCATGCTTCAGCAATCACCCAGTTTTCCTTTCTTTAGTTTTATggcgccaccgccaccaacaacggcagcggcagcagcagcagcagcaacagctgcagacaagtcaatgacaacaaatccaacagcagcagcagccggcgcaacagcagcaacaattgctgcaatGCCACTGTCGCTGCCAGTGCCACTGGCCGCTGGTGGTCCCGTCAAGATGGTCATCAAGAATGGCGTCCTGATGcccaagcagaagcagcgccGCTATCGCACCGAGCGCCCCTTTGCCTGCGAGCATTGCTCGGCCCGCTTCACCCTGCGCTCCAACATGGAGCGGCAcgtgaagcagcagcatccacacTTCTATGCGCAGCGCCAGCGACACCGCAGCGGTCATCATGTGATGCGTGAACGGGCTGCATCATCGAGTGCTGCCCAAGCGGCAGCCGCTGctcaggcagcagcagccgccgccgccgcagcaatGAGTAAtctcagccagcagcaacagttgcagcagcagcagcaacagttgcagcattcgcattcacatcaCGTCCATGCGCCAATCTCGGAGCAGgtgaaatatgcaattttggCGCAGCAATTGAAGGCGCGCAAGGATACCGATTTGTTGCAACAGGCACTGGCACATGGCTCCAGCAGTGTTGTCGCCAATCCGCTGTTGCATTttagctacaacaacaacaacggcaacggcaacagcatcagcagcagcaagcagcagcaacaacagttgtgCAACAACACTGGCAACTCTTTGGTGCTGGACGACGATGAGCCGCCTAAGCTGATCATTGACGAGGATGACGAGGATGTGGATGGCgaggacgatgaggatgaggaggaggagcaggaatTTGATGTTGATGAGGAGGATCAGGAGGACGAGGAGATGGATTTGGACGatgagcatcagcagcagccacacgaggacgatgacgatgatgatattgatgatgatgatgcagcagcagcagcagcagcagctactgcAGCAGAGGCGtcgcagcaacaattgcagccaaCCAAGGACAAGCTGCAATCCAAGCCAATTGAGGCGGCCAAAAAGGTAGCGGAAACCATATTGGAGCAGGCAATCAAAGAGCGCGAGGAGAAAGCCGCCGAGAAGCAGCCGCATCCTCAATCGGAGTCCATCGGCGGCAATAAGCCGGCGACGCCAACCACAATGAAAACGATGATTGCACAAGCTGAATCGGTAGCCAAGTCCTTGAAGGAGGTGGCCAGTTCACCGTTCAAGGATGAATCTCAGGATCTGGTGCCGGTCGCCAAACTGGTGGACAATGCGACCAGCAATCAGGTGTCGTTCAACAGCTATTTCCGTCCCAGCGACGTCGCCAATCACATGGAGCAGAGCGACGAGGAGGGTCTCGTTGCTAGCGGCAGCGCCAGCGAGAGCAACAATTCCGGCACCGAGGAtgtgaccagcagcagcagcagctgcggcaatGACACCAAAAAGAAATCCGCCTACAGCCTGGCACCGAACCGTGTCAGCTGCCCGTATTGCCAGCGCATGTTCCCCTGGAGCAGCTCGCTGCGTCGCCACATCCTGACGCACACCGGCCAGAAGCCGTTCAAGTGCTCCCACTGCCCGCTGCTGTTCACCACGAAGAGCAACTGCGATCGCCATCTGTTGCGCAAGCATGGCAACGTTGAGTCCGCCATGTCCGTCTATGTGCCCACCGAGGATGTCAGCGAACCGATACCCGTGCCCAAGTCCGTCGAGGAGATTGAGCTCGAGGAGCAGCGACGTCGCCAGGCGGCCGAAGCCGAACAGGCCGAGCGTGAGCAGCGCGAGCGCCAAAAGGAGCGCGAACGTGAACTGGAAttggaacgggaacgggaacgggaacacCAACAGTTGATACAACAGTTGCGCCAACAAAtggccgctgctgcagcggctgctgtcGCTGTGGCCGCCGTTGCTGCACCAGCGCATCCACCACCGCCAGACCAATCGCCACCAGGCCTGGAGGCGAGCAGTGATCTCCCCTACAAATGCCATCTGTGCGAGTTCTCATTCGGCGAGCGGCTGCAGTGTCTCGAGCACATCAAGCAGCTGCACGCACACGAGTTCGccctgctgctggccaagggAGCCATCGAAACGGATGCCCAGctgcagcaccaacagcagcagcagcagcaacagttgccagcgACTGGTGGCGCTCCGCATTCGGATgatgaggctgctgctgtcggcaCCAGATCGGGCAAATATCCCGACTATAGCAATCGTAAAGTGATTTGCGCATTTTGCGTGCGTCGCTTCTGGTCAACGGAGGATCTGCGGCGCCACATGCGCACCCATTCCGGTGAGCGGCCGTTCCAGTGCGAGATCTGCTTGAGGAAGTTCACATTGAAGCACAGCATGCTGCGACACATGAAGAAGCACAGTGGACGCAGTCACAATGGTGGCGAGCTCGATCATCAATCCGATTGCTCCGAAGATGAGCAACTGTTGTCCTGCTCCCCACCCTCAACGCCAACGCCcactaacaacaataacaacaacacttgccagaacaacaacaacaataacaacaacaatagcaatagcaagcAGGTGCTGCGCGAGCTGCTGGGCAAGGCGAACGAGTGGCGAGTGAGTCGCCTGGGTGAGCACAAGGAGAATATTGccgaggcaacaacaacaccctcagcagcaacagcagcagcggcagcaacagctgcagccgcagcagcagcagcagcagccgctgtgGCCAGTGGCGATCTAATTGGTAATCTGTTGGGGATCAGTGATCAGGGCATACTAAACAAGCTGCTCTCCTCACCAGACGAAGCTGCCAAGCTGCTAGGCGTGGAGAAGTAA
Protein Sequence
MLATQQQQQQQQQQQQQQATAASAATHEDARDLELMETRQRRDSSTSESSLEHLDLGRTPKKLSSSSGAPQPTSTPHDTAVTATSRKRKLRQQHHQQQQQLPLSDEEQQQQQQQQQQLLDSSAQRPRHKQRRGGVAAAASASIVVDYSASGDASSLRKKFRLNRSSASSNAANGDLSESGFVDGSALSGYLLGSNNNNNNNNNNNNNNNNNISNSSSSSAVAQSAAAAASAAQHAPSVSSSGGSSPQGLSSAESGIGAGDEHMKYLCPICEVVSATPHEFTNHIRCHNYANGDTENFTCRICSKVLSSASSLDRHVLVHTGERPFNCRYCHLNFTTNGNMHRHMRTHKQHQASQQQQQQQQQHSQQQQSTQQQQQAQSQQQQQQRRQQHAGGAGAAGSVSGSAQLLTTRAESYESDASCSTDVSSELNSHSSNSNQSNHNNNNNNNNSHKTNNNNNNEDELELDDEQLVLSSKQRRHKAALNNNNIIRDEEHDNRPDDDSDVDSADSVAQVITSTPDVATLLASGGTSPTHSHSESHSPPLLLQSCPACNSGEFESVPALCAHLDAEHADIPAKCRECDVIFATHRQLQAHSCRGLPPLLGVSSSPLHKQEESELEEQHQQQQQHEEDHEQQQHKQEEQEQAEQRECEDFFQQLYLKNKSSATLLPSPIKHEPADQRQDLADIQSILNMTNSSCTSSFLRNFEQSVNTPCSSQYSVDGRDGEEEAQDAFTNEFRRMKLRGEFPCKLCTAVFPNLRALKGHNRYHLSEVGAAGPFRCNMCPYAVCDKAALVRHMRTHNGDRPYECAVCNYAFTTKANCERHLRNRHGKTSREDVKRAIVYHPAEDASCEENKSRTEADILTELSGYRCATPTEHSSSASSSSQLKHMLLAEPTPAVKVAATTAAAAAAAAATTTTSLPQQPLKIQVKSLDQLVDKPLPALDLSMDALDLSKKPAQLLAEQREQREQLERHELLLQQQQQHQQQQQQQQQQQLFGAGDAAAQYMQQLLRSFMLQQSPSFPFFSFMAPPPPTTAAAAAAAATAADKSMTTNPTAAAAGATAATIAAMPLSLPVPLAAGGPVKMVIKNGVLMPKQKQRRYRTERPFACEHCSARFTLRSNMERHVKQQHPHFYAQRQRHRSGHHVMRERAASSSAAQAAAAAQAAAAAAAAAMSNLSQQQQLQQQQQQLQHSHSHHVHAPISEQVKYAILAQQLKARKDTDLLQQALAHGSSSVVANPLLHFSYNNNNGNGNSISSSKQQQQQLCNNTGNSLVLDDDEPPKLIIDEDDEDVDGEDDEDEEEEQEFDVDEEDQEDEEMDLDDEHQQQPHEDDDDDDIDDDDAAAAAAAATAAEASQQQLQPTKDKLQSKPIEAAKKVAETILEQAIKEREEKAAEKQPHPQSESIGGNKPATPTTMKTMIAQAESVAKSLKEVASSPFKDESQDLVPVAKLVDNATSNQVSFNSYFRPSDVANHMEQSDEEGLVASGSASESNNSGTEDVTSSSSSCGNDTKKKSAYSLAPNRVSCPYCQRMFPWSSSLRRHILTHTGQKPFKCSHCPLLFTTKSNCDRHLLRKHGNVESAMSVYVPTEDVSEPIPVPKSVEEIELEEQRRRQAAEAEQAEREQRERQKERERELELEREREREHQQLIQQLRQQMAAAAAAAVAVAAVAAPAHPPPPDQSPPGLEASSDLPYKCHLCEFSFGERLQCLEHIKQLHAHEFALLLAKGAIETDAQLQHQQQQQQQQLPATGGAPHSDDEAAAVGTRSGKYPDYSNRKVICAFCVRRFWSTEDLRRHMRTHSGERPFQCEICLRKFTLKHSMLRHMKKHSGRSHNGGELDHQSDCSEDEQLLSCSPPSTPTPTNNNNNNTCQNNNNNNNNNSNSKQVLRELLGKANEWRVSRLGEHKENIAEATTTPSAATAAAAATAAAAAAAAAAAVASGDLIGNLLGISDQGILNKLLSSPDEAAKLLGVEK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00535518;
90% Identity
iTF_00525357;
80% Identity
-