Basic Information

Insect: Drosophila engyochracea
Gene Symbol: hang
Assembly: GCA_035042385.1
Location: JAWNLK010000167.1:11082343-11098882[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 18 0.37 23 5.6 1.0 3 23 508 529 507 529 0.93

2 18 0.46 29 5.3 3.2 3 22 636 655 634 655 0.89

3 18 0.00079 0.05 14.0 3.3 1 22 764 785 764 787 0.90

4 18 0.091 5.7 7.5 0.1 2 21 799 818 798 819 0.93

5 18 0.00091 0.058 13.8 0.2 2 23 961 983 960 983 0.95

6 18 0.0026 0.17 12.3 0.1 1 23 991 1014 991 1014 0.96

7 18 0.0002 0.013 15.8 0.2 2 23 1102 1123 1101 1123 0.97

8 18 0.00038 0.024 15.0 2.9 2 23 1223 1245 1222 1245 0.97

9 18 0.03 1.9 9.0 0.2 2 23 1254 1276 1253 1276 0.95

10 18 0.0018 0.11 12.9 0.3 1 23 1289 1312 1289 1312 0.97

11 18 0.00016 0.01 16.1 1.1 1 23 1370 1392 1370 1392 0.99

12 18 0.0026 0.16 12.4 0.9 1 23 1400 1423 1400 1423 0.96

13 18 0.089 5.6 7.5 0.4 2 19 1431 1448 1431 1449 0.94

14 18 0.002 0.13 12.7 0.3 3 23 1559 1579 1558 1579 0.98

15 18 0.0014 0.087 13.2 0.1 1 23 1614 1636 1614 1636 0.97

16 18 0.00078 0.049 14.0 0.6 2 23 1728 1750 1727 1750 0.93

17 18 0.0084 0.53 10.7 0.3 3 23 1806 1826 1806 1826 0.98

18 18 0.0051 0.32 11.4 1.8 1 23 2285 2307 2285 2307 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	18	0.37	23	5.6	1.0	3	23	508	529	507	529	0.93
2	18	0.46	29	5.3	3.2	3	22	636	655	634	655	0.89
3	18	0.00079	0.05	14.0	3.3	1	22	764	785	764	787	0.90
4	18	0.091	5.7	7.5	0.1	2	21	799	818	798	819	0.93
5	18	0.00091	0.058	13.8	0.2	2	23	961	983	960	983	0.95
6	18	0.0026	0.17	12.3	0.1	1	23	991	1014	991	1014	0.96
7	18	0.0002	0.013	15.8	0.2	2	23	1102	1123	1101	1123	0.97
8	18	0.00038	0.024	15.0	2.9	2	23	1223	1245	1222	1245	0.97
9	18	0.03	1.9	9.0	0.2	2	23	1254	1276	1253	1276	0.95
10	18	0.0018	0.11	12.9	0.3	1	23	1289	1312	1289	1312	0.97
11	18	0.00016	0.01	16.1	1.1	1	23	1370	1392	1370	1392	0.99
12	18	0.0026	0.16	12.4	0.9	1	23	1400	1423	1400	1423	0.96
13	18	0.089	5.6	7.5	0.4	2	19	1431	1448	1431	1449	0.94
14	18	0.002	0.13	12.7	0.3	3	23	1559	1579	1558	1579	0.98
15	18	0.0014	0.087	13.2	0.1	1	23	1614	1636	1614	1636	0.97
16	18	0.00078	0.049	14.0	0.6	2	23	1728	1750	1727	1750	0.93
17	18	0.0084	0.53	10.7	0.3	3	23	1806	1826	1806	1826	0.98
18	18	0.0051	0.32	11.4	1.8	1	23	2285	2307	2285	2307	0.99

Sequence Information

Coding Sequence: ATGTGCGAcgctgccacaacaacaacaacaacagcagcaacaacaactgcagcagcagtagcacaAGGAACAGGAGTTGCTGGCGATACAGCGATGGAAGAACAAAATCAACGAGAGCGACAAAGCTGCTGTCGTCTGTGCCTTGCGCCCGCCAGCGAATGCATTTCGATCATTAACAGTTATGCGGCCGATAAGGAGCCGCTAGCCACTAAAATACACAACTGCGTAAATATCAAGATCACATCGGTGGATCGTCTGTCGTTGCATATTTGCCATGCCTGCATCAGTTATTTGAACTCATGGCAGAGCTTCAAGAATCGCTGCCTCAGCTCACAGTCGAAGCAGCGCCATTGGCTGGAGACGGACAAAACCAAGCAGCAGACGCTACTCGGATACTTGGATTTGAACAGGGCCGAGAATGGCAGCACCATtgaccaacagcaacaacagcagcagcaacaacagcagcacgaTTTAAAAATGGATTCAGCGACGTCTGCAGCTGAAAAGGCGTCCGCAGCCAACATTTTGGATGGCATACCTCAGCTGAAGAAACGCAAATCGTTAACAGTCTATGTGAGTCCGAGTcccaagcaacagcagcaagcacagcaacaacagtcgcagcaacaTTCTCAGCAACAGCATGCAACAGGGGCAAGATCAACAACGAAAACATCAGCTGCgtcggcggcggtggcagaGTCGCAACAAACATTGCAAACCCTTTTATTGCAGGTGcccacatcagcagcagcagcagcagcgacattGGCAACGTCgtcaacacagcaacagcaacagcagcgcaagtatcaacagcagctgcagcagcaacgtggcaagcagcagcaacatcagtatcatcaacagcagcagcggcagagtCGCGTTCGCCAACCgcgacgacagcaacaagcgGCAACGAGCAAATTCAGGAGCAAGTTGTATGTGCCACTGGATATATCGGTGCCAGCGCTGCCAACGCTgttgccgccaccgccgccagctgttgctgatgcagcgtcgttgccattgccgctgtcgctgccacTTGATTTCAGCCAGAATCCGAATCCAAATCCCAATCCAAATCAAAATCTAAATCAGAGATATACAAGTTGCGTTTTAGTGCCGCAGCCGCAGGCGCCGCCGATGCCGCTGCCCCCGCCAGTTGCAATAATGAGCAGCAACGAGGCTGCCATTGGtggtgcaactgcaactgcaaccgcaGTCACGACTCCATTGCTCATGCCGCCGCTGCCTGCCATGCCCATCAAGGATGAGCCCCAGGACGATACGGATGATGACTTTCAAATGAAGTGCATAGACGAATCCGATGATATGATGGATCCCACAATGTTCCTAGAGCGCTCCGAGCACGAAGGCGATGTGCCACTAAATACCTCCGACTATGATTATACGGCTCAGCATGGCGTGACCGCTGTTGTGGCGGCTGCATCGCTGCCGGCCAGCGCCGTTGCGAATGTGGCCGCCGCTGGCGACTCGAAGGTGGCCAGCTGCCGGGCGTGCAGTCTGCAGTTCTCGACGCGGGCGAATGCCCGTCGCCACGAGCGCAATCTGCATCCGAATCTGTTTCAATTGTCGACAGACTCACCAAATAATACGCCAATCACCAAACCAACACCGGCCCTCGCCGCCGCCTTGGAAATACAGCgtgcagcggcggcggcagcggcaaccgCTGAGGCAACGCGTGCCGCTGCCGGTGGCAATATATCGGCGCAAAAGTATCGACAGGTGGTGATGAACACGTTCAGCAAATGCGAAAACGGTGGCTTCGACTACGACAATCCCGAACAGTATCAGCAGCTGTTGTCGCACGACAAGATCGACTTCATACAGGATAACACCGAGTTTCTCGAACAGTACCAGACGATGACGTGTCGCTGTTGCAACAAGTACTTCAGCACGTATAAGAACTTTATGGCGCACGTGCGCAAAAAGTATCCGTTGCTGCCGCGCAACCTGTGCTTCAACTGCCTCAAGATGAACGACTCGAAGGCGCTGTTCATATCGCACCTGAAAAAGCGCAACTGCATCAATTTGTATCGTGTGCTCAACTCACTGCGCACCAAACAGCCAAACTTTGTctatgccaatgccaatgccaatgccccATCCACTTCCACTGCAGCCGCAACGACTGCTgtacaccagcagcaacagttggtgACAGCAAacgaaacagcagcaacaacaacaccaacaacatcaacggATCGTCCGGAGAAGTTGCGTGCCAAGGAGCTGCTGGTTAACAAGCTGTACGAGTGCAAGCTGTGCCCAAAGGGTTTTCGCACAAAGCACGAATTCCGCACCCATGTCTACGACAAGCATGCAGATGTTCAGCGCAAGGATAACAATTCGATACAGTGCAGCTTCTGTGGCCTGGACTTTGCCGATCCCGTTGATCGTCGAAGACACTACAATAATATGGATTGCATTGTCCGGCTGCGCTGCATGACTTGCGATGCGAAACTGGAGACGCATCAGCGTTTCCTCGACCATGTCTATCAGGATCATTTGGGTGGAGTGAGCAGTGATAATGCATCGTCCACGGCGACGACCAGCGGCTTGGATCATTCGTCCGGCAAGCGCAGTTTGCTGGGCGCCCTTGGCATCGGCATTGTCAGTCAATCATCCAATGATGAGtcgcgcagcagcaacagcaacaaccacaacaataacaataataacaacagtaacaacaacaacaacaataatacacCTTTAACTTCGACACCTAAACTACCAATCGtcacaggagcagcaacagctggtggaggaggaggagcagcagcaaccagtgGCAGTCGAGATGCACCCAAATCACAGTATTTCTCACGAATGCCACAGGTCTGTCCGATCTGTGGCCAGCAgtacaacaactataacaatgTGTTGCGTCACATGGAATCGAAGCATCCCAACAAATTGCCGGAGACATATAAGTGTGTCCGCTGCGGATTGGGCTATCCGCGGATCTCCTATCTGCGGGAGCACATGATCAATGTGCATGGCGTTGACAAGAATCGGCATTCGGGCGGCTTTGAATATATTGTGAATGCCGATGCGGTTAAATTGGCGGATGGCAGCACGCCCAATGTCTATACAGGACGATATGATTATGTGATGAAGGATCTGATGTCAATAACAAATGGTGGGACACTCgatgatgatgacgatgaagGCGGCAACATTTCCAAAAAGATGAGACTCGAtgatagcagcaacaacagcagcagcatcaacatgAGCAGCATTGCCAACCAGCAGAAGGAGTGCCTCATCTGCAATGCGGTGTTTAGCAACAATATTGGTCTATCGAATCATATGCGTTCCCATTACACAACATCGATAACGACAAGTGCTGCTCTGGCGGTTGCCAATCGTATGACGCCCAAATCGCtgacaataacagcaacgcCACCGCTGGAGacaacgacgtcaacaacaactgcagctggagttgcagcagtggcagcatcatcatcaggaGCAGTCGCctcaactgcaacagcatcaggATCAGGCTCATCATCCGGTAACTTGCCGCCAGCAATGGTGCATCAGACGGCACAGGAGCAGGCGGTATTCCGTCGCAGCCTGGATCAGGCGGCCGATCGACGATTCCGTCGAATGCGCTGTCGCATTTGTCAGCGCAGATTCAGTTCGAAGAAATCGTATCGCTACCACATGCTCACCGACCACCAGGTGCAGAATGTGCAGTTCATCAAGTGCAAGCTGTGCAATGCGGAGTTTGCCTACGAGAAGGGGCTCAAGGTGCATCTGTTCAAGGTGCACGGCCGGGCCATCAAAGATGAGATGATTATCAAGCAGTTCGAGTGCGATGTCTGCTCCACGGTCTACAGTTCCGAGCTGGaattgcagcagcacaagcgCAGCGTACACAAGTCACACGCCAGTGATTCATCATCAACTGCAGCTGGTGGTGCAGGTGCTGCTGTCAAATCATCATTGAAATCTGCTACTGCAACTACCTCATCGACAGCTGAGCTAATCGCAGACACATCATCCTCCTCGGGCACGGGGGGTGCGGCCATTTTGCTGCCACTTTACTGGTACCAGTGCAAATATTGTCCATCCAATTTCAACACCAACAAGAAACTGGCCATCCACATCAACTCGCACGACGAGTTCGACTCGAATGATTACTCGTGCAAGGACTGCGGCAATGTCTACAGCGGCCGCAAGAGCCTCTGGGTGCATCGCTACAAGAAGCATCCGCAGGTGCCGGATCCCGCCGAGTGCACGCTGTGCCGCAAGATGTTCTTCGATCGCCAGATGCTGGAGAATCATACGCCCACCTGCAATCGCAAGCCAATCACTGCCACCGGCGCCCATCAGcaggatcagcagcagcagcagcagcagcaacaacaacagcagcagcagcagcaacaacagctgcagctgcaacatcaTCAGCGACTCATCTTTAAGCACAAAACGggagatgatgatgacgaggaggaggacgatGATCAGTTGCTGCTAATGGACGATGGCGGTGGCGGCAGCAATGATAGCAATGCTGGCAATGCTattgcatcagcagcagcagcagcggcagcagcagcagtcacaatAAATACGAGCACAATGAAGATACGCATTCCGGAGGTTGCATGCACCATTTGCGGTGCCCGTTTCACCGATCAGGAAATATTCACCAAGCACATACAGAAACACGAACAGGAACTGTATGTGGACAATCCGTTGGCGGCGATGTTCGATGATGGGCCAGCGGATGCCGGTCAATTTCAGGTTGAGCACCAGAACGAGAATGGGGAATACGCGTGCGATTTGTGCACCAAGACGTTCCCGCAGGTGATAGCGCTCAAGGTGCATCGCAAGTGGCATTTCAGAGGTGATAGCAAGCAGATCCCAACCAACGACGGCGAAGCGACAACGctgaacaacagcagcaacaacagcagcagcagcaacaacaacaacaacaacaattcgctGAGCTCATCATCGATGCTGCATCTACGCGAACTGCATGCGGTGGGCCTGATGcccaatcagcagcaacacaagaaacaacaacagcagcagcaacagcagcagcaaaatcagcagcagcagcaacaacggacGAGCAAATCAATGAAACGGAAACGTGAACTGAAATGTGAATACTGCGCCTCCACAttcattagcaacaacaacctgcGACGCCACATGTACGAGCTGCACAAGCACGAGGTCAGCAACCTGCCAGAGCCGCCCGTGATTGAGGTGGATGAGCCGTTGGCGTGTCGCCGTTGCGGCGATCTACAATTTGATACCAAAGAGCAGTGGATCGAGCATAAGCTGGCCGATGCGAGAGTGGTGCGTCCATTCTGTCCATTCCAATGGGGCTGTGATCTGTGCGGCGAGTATTTGTCGCGCAAGGAGAAGCTCATCAATCACATTAACAATCATCTCAAGGAGGATGTAATTGTGCCGGTCGCCACCAAGCCACCAgcaccggcagcagcagcagccaataaaactgcagcggcagcagcagcagcaacaacaacaacaacaacaactgcggcaacaacaccaacaattgCCTACGCAGTAACACATGCAGCTGCtaagtcagcagcagcagcagcagcaacggcggcGACGAAgtcaacgacaacagcagcaaaagaactGAAGgctaaacaacagcagcaggaggatgATGACCTGCAGCTGGATGATGAGAAGCTaacgaagcagcagcaccagcagcaacaggaggaggaggaggatgataGTGATATGGAAGATGATACCGATAGTGGCAATGATGATGAGGACGGCAGCACCAGTGCtgacgatgatgataatgatgacgatgatgatgaggagggCGATgtcgatgacgacgatgatgatgatgacgaagaagaagacaatgacaatggtgaaaatgttgttgcacagcagcaaatactgcaacaacagcctcaaaatacaaacaccaataacaacaacaacaacaacaacagcagcgctaTTGAAAATGACGATGATCTCATTGAGGAGGTGATCGAGGATGATGGCATTGTCGAGCAGCTGGacgtcgatgatgatgaggaagacgatgatgacgatgacgacgatgacggcgatgatgatgatgatggcgaagacgatgacgacatcgatgaggatgaggatgatcCGCCGAGACGCCACAATTTCGACTACTCGCGCACCGACAGCGCCAAGCTAAATGGCAACGGTGGCAAACAGtctgtgacaacaacaacaaaatcaaagacacagccacagttgcagcaacagttgcagacACAGCCAATGCTGGTCATGCACAGTAGTAGCAGTCGCCACGTGAATGATGGCGAGGAGGAGGTGGATGATAtggatgatgatgttgatgacgatgatgttgTGGGTGAAGCGATGACCATTGATGATATTATTGAAGAGGATGATGGTGTGGATGATGACGATGTGGTTGGTGTcggtggtggtgttgttgaggatgatgatgatgacgacgaagatgatgatgacgacgatgaggatgatgatgttgaGGAGGGCatggacgatgatgatgatgatgatgatggggacGACGACGATGCCGATTTCAACAACACCAATATTGGCAACGGTGTTGGCCGTGTGGGTCGAGaagatgctgatgatgttggtGATGgggatggtgatggtgatggtgatgttAATGTTGATGGTGGTACATCATCATCTGAGAGCgagtcgacaacaacaacatcgcaTTCAACTGCGGCACATGGCGCTGCCGCTGATCAGTCTAATTCCAGCTATACGTGTGATCTATGTCAACTTTGTTTCGATTCCCAGGAGATACTGCAGACTCATATTAAAAGTCATTTCCTCAATGGGCCATTGGcggggagcagcagcaacagcaacaagagcaacggCGCCAGCAGGagcaccaacaataacaacagcaacaacaacagtagtaacagcaacagcaacagcagtaacaaaaTCAATACCAAAAAGTCCGGCTTGGATGCAacgaagacaacaacaacaacaacaacagttaagGCTGCTGCAGTAGCGGACGCTGCAACGGGCTTCAACTGA
Protein Sequence: MCDAATTTTTTAATTTAAAVAQGTGVAGDTAMEEQNQRERQSCCRLCLAPASECISIINSYAADKEPLATKIHNCVNIKITSVDRLSLHICHACISYLNSWQSFKNRCLSSQSKQRHWLETDKTKQQTLLGYLDLNRAENGSTIDQQQQQQQQQQQHDLKMDSATSAAEKASAANILDGIPQLKKRKSLTVYVSPSPKQQQQAQQQQSQQHSQQQHATGARSTTKTSAASAAVAESQQTLQTLLLQVPTSAAAAAATLATSSTQQQQQQRKYQQQLQQQRGKQQQHQYHQQQQRQSRVRQPRRQQQAATSKFRSKLYVPLDISVPALPTLLPPPPPAVADAASLPLPLSLPLDFSQNPNPNPNPNQNLNQRYTSCVLVPQPQAPPMPLPPPVAIMSSNEAAIGGATATATAVTTPLLMPPLPAMPIKDEPQDDTDDDFQMKCIDESDDMMDPTMFLERSEHEGDVPLNTSDYDYTAQHGVTAVVAAASLPASAVANVAAAGDSKVASCRACSLQFSTRANARRHERNLHPNLFQLSTDSPNNTPITKPTPALAAALEIQRAAAAAAATAEATRAAAGGNISAQKYRQVVMNTFSKCENGGFDYDNPEQYQQLLSHDKIDFIQDNTEFLEQYQTMTCRCCNKYFSTYKNFMAHVRKKYPLLPRNLCFNCLKMNDSKALFISHLKKRNCINLYRVLNSLRTKQPNFVYANANANAPSTSTAAATTAVHQQQQLVTANETAATTTPTTSTDRPEKLRAKELLVNKLYECKLCPKGFRTKHEFRTHVYDKHADVQRKDNNSIQCSFCGLDFADPVDRRRHYNNMDCIVRLRCMTCDAKLETHQRFLDHVYQDHLGGVSSDNASSTATTSGLDHSSGKRSLLGALGIGIVSQSSNDESRSSNSNNHNNNNNNNSNNNNNNNTPLTSTPKLPIVTGAATAGGGGGAAATSGSRDAPKSQYFSRMPQVCPICGQQYNNYNNVLRHMESKHPNKLPETYKCVRCGLGYPRISYLREHMINVHGVDKNRHSGGFEYIVNADAVKLADGSTPNVYTGRYDYVMKDLMSITNGGTLDDDDDEGGNISKKMRLDDSSNNSSSINMSSIANQQKECLICNAVFSNNIGLSNHMRSHYTTSITTSAALAVANRMTPKSLTITATPPLETTTSTTTAAGVAAVAASSSGAVASTATASGSGSSSGNLPPAMVHQTAQEQAVFRRSLDQAADRRFRRMRCRICQRRFSSKKSYRYHMLTDHQVQNVQFIKCKLCNAEFAYEKGLKVHLFKVHGRAIKDEMIIKQFECDVCSTVYSSELELQQHKRSVHKSHASDSSSTAAGGAGAAVKSSLKSATATTSSTAELIADTSSSSGTGGAAILLPLYWYQCKYCPSNFNTNKKLAIHINSHDEFDSNDYSCKDCGNVYSGRKSLWVHRYKKHPQVPDPAECTLCRKMFFDRQMLENHTPTCNRKPITATGAHQQDQQQQQQQQQQQQQQQQQQLQLQHHQRLIFKHKTGDDDDEEEDDDQLLLMDDGGGGSNDSNAGNAIASAAAAAAAAAVTINTSTMKIRIPEVACTICGARFTDQEIFTKHIQKHEQELYVDNPLAAMFDDGPADAGQFQVEHQNENGEYACDLCTKTFPQVIALKVHRKWHFRGDSKQIPTNDGEATTLNNSSNNSSSSNNNNNNNSLSSSSMLHLRELHAVGLMPNQQQHKKQQQQQQQQQQNQQQQQQRTSKSMKRKRELKCEYCASTFISNNNLRRHMYELHKHEVSNLPEPPVIEVDEPLACRRCGDLQFDTKEQWIEHKLADARVVRPFCPFQWGCDLCGEYLSRKEKLINHINNHLKEDVIVPVATKPPAPAAAAANKTAAAAAAATTTTTTTAATTPTIAYAVTHAAAKSAAAAAATAATKSTTTAAKELKAKQQQQEDDDLQLDDEKLTKQQHQQQQEEEEDDSDMEDDTDSGNDDEDGSTSADDDDNDDDDDEEGDVDDDDDDDDEEEDNDNGENVVAQQQILQQQPQNTNTNNNNNNNNSSAIENDDDLIEEVIEDDGIVEQLDVDDDEEDDDDDDDDDGDDDDDGEDDDDIDEDEDDPPRRHNFDYSRTDSAKLNGNGGKQSVTTTTKSKTQPQLQQQLQTQPMLVMHSSSSRHVNDGEEEVDDMDDDVDDDDVVGEAMTIDDIIEEDDGVDDDDVVGVGGGVVEDDDDDDEDDDDDDEDDDVEEGMDDDDDDDDGDDDDADFNNTNIGNGVGRVGREDADDVGDGDGDGDGDVNVDGGTSSSESESTTTTSHSTAAHGAAADQSNSSYTCDLCQLCFDSQEILQTHIKSHFLNGPLAGSSSNSNKSNGASRSTNNNNSNNNSSNSNSNSSNKINTKKSGLDATKTTTTTTTVKAAAVADAATGFN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00596083;
90% Identity: iTF_00486003;
80% Identity: -