Dema014685.1
Basic Information
- Insect
- Drosophila emarginata
- Gene Symbol
- -
- Assembly
- GCA_037075365.1
- Location
- JBAMCD010000260.1:2465661-2466086[-]
Transcription Factor Domain
- TF Family
- zf-LITAF-like
- Domain
- zf-LITAF-like domain
- PFAM
- PF10601
- TF Group
- Zinc-Coordinating Group
- Description
- Members of this family display a conserved zinc ribbon structure [3] with the motif C-XX-C- separated from the more C-terminal HX-C(P)X-C-X4-G-R motif by a variable region of usually 25-30 (hydrophobic) residues. Although it belongs to one of the zinc finger's fold groups (zinc ribbon), this particular domain was first identified in LPS-induced tumour necrosis alpha factor (LITAF) which is produced in mammalian cells after being challenged with lipopolysaccharide (LPS)[2]. The hydrophobic region probably inserts into the membrane rather than traversing it. Such an insertion brings together the N- and C-terminal C-XX-C motifs to form a compact Zn2+-binding structure [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 1 3.7e-21 5.1e-18 65.4 12.2 2 68 31 97 30 99 0.95
Sequence Information
- Coding Sequence
- ATGGAAAAGTCTTGCTACTCTTTGGGTCCCATAGAACAACAAACTTCACCTGTATTGGTCATCAACTCCAATGATATACAATTGGGTCCTGTGCCCCAACGCATGAAATGCAAACATTGCCATGTAATAATGGAGACGTGCATAAGGAAACGAGTCACCAGATACACTCATGCCTTTGCTTTGGCCTTTTGCCTTACTGGCTTGTTGTGCCTAATTCCGTTACCTTATTGCCTGAAAAGTTGCCAGAGTTTGGATCATTATTGTACAAGTTGTAATCAATTTCTGGGAAAGGCGGCAAACTAA
- Protein Sequence
- MEKSCYSLGPIEQQTSPVLVINSNDIQLGPVPQRMKCKHCHVIMETCIRKRVTRYTHAFALAFCLTGLLCLIPLPYCLKSCQSLDHYCTSCNQFLGKAAN
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00556242; iTF_00591375; iTF_00578193; iTF_00484115; iTF_00600727; iTF_00503667; iTF_00612487; iTF_00571577; iTF_00524094; iTF_00604510; iTF_00555510;
- 90% Identity
- iTF_00591375;
- 80% Identity
- -