Basic Information

Insect: Drosophila emarginata
Gene Symbol: RREB1
Assembly: GCA_037075365.1
Location: JBAMCD010000174.1:2303352-2309972[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 13 0.038 3.3 8.7 0.8 1 21 248 268 248 270 0.93

2 13 0.00035 0.031 15.1 0.2 1 23 280 302 280 302 0.98

3 13 8.5e-05 0.0075 17.0 7.3 1 23 308 330 308 330 0.98

4 13 7 6.2e+02 1.6 0.2 2 23 566 589 565 589 0.87

5 13 0.77 67 4.6 6.3 2 19 595 612 595 614 0.97

6 13 0.0032 0.28 12.1 0.2 1 23 794 816 794 816 0.97

7 13 8.7e-06 0.00076 20.2 1.3 1 23 826 848 826 848 0.99

8 13 0.00088 0.077 13.9 2.0 1 23 854 877 854 877 0.97

9 13 0.0031 0.27 12.1 2.0 1 23 1152 1175 1152 1175 0.95

10 13 9.1e-05 0.008 17.0 0.3 2 23 1545 1566 1544 1566 0.97

11 13 0.15 13 6.8 6.3 1 23 1572 1595 1572 1595 0.97

12 13 0.0089 0.78 10.7 0.5 3 23 1798 1818 1796 1818 0.96

13 13 0.0014 0.12 13.2 4.8 1 23 1824 1846 1824 1846 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	13	0.038	3.3	8.7	0.8	1	21	248	268	248	270	0.93
2	13	0.00035	0.031	15.1	0.2	1	23	280	302	280	302	0.98
3	13	8.5e-05	0.0075	17.0	7.3	1	23	308	330	308	330	0.98
4	13	7	6.2e+02	1.6	0.2	2	23	566	589	565	589	0.87
5	13	0.77	67	4.6	6.3	2	19	595	612	595	614	0.97
6	13	0.0032	0.28	12.1	0.2	1	23	794	816	794	816	0.97
7	13	8.7e-06	0.00076	20.2	1.3	1	23	826	848	826	848	0.99
8	13	0.00088	0.077	13.9	2.0	1	23	854	877	854	877	0.97
9	13	0.0031	0.27	12.1	2.0	1	23	1152	1175	1152	1175	0.95
10	13	9.1e-05	0.008	17.0	0.3	2	23	1545	1566	1544	1566	0.97
11	13	0.15	13	6.8	6.3	1	23	1572	1595	1572	1595	0.97
12	13	0.0089	0.78	10.7	0.5	3	23	1798	1818	1796	1818	0.96
13	13	0.0014	0.12	13.2	4.8	1	23	1824	1846	1824	1846	0.99

Sequence Information

Coding Sequence: AtgttagcaacaacaacaacaacagcagcaacagcatcaacatcaacagaaATGGAACGTCAACGCAGAGATTCCACAACCTCAGAATCCTCATTGGAACATCTTGATCTTGGCCGCACACCAAAGAAATTAAGCAGCGCCAGCGGAACGCTGCAGCCAACCTCAACGCCACATAatgtaacagcaacaacaacaacgacatcGCGTAAGCGTAAATTGcgtcaacaacagcatcatcatAATCAGCATGGCTTACTCTCACTGTCCGAAGATGATGAAGACGGAGAGGAGGAGTCATCATCTGCtgcagcatcaacagcagttATAGTGCAGCAACGCCCACGCCATAAACAGCGACGCAACGGTACTGTTGCCGCCGCTGCCAGCGCCAGCATTGTGATGGATAGCGGTGCTGATGCGAACTCACTGCGCAAGAAATTTCGATTAAATcgcagcaatagcagcagcctCCTAAATGGCGAATTATCTGAATCGGGCTTTGTTGATGGCAGCACACACAGTGGCTATCTAATGGGCAATGGCAACGGTAGCGTTACTCACTCATCGAATTCAGCCTCTGATGCTGCTGcagccgctgccgctgctgccagTGCATCTGCTGTCAGTCATAGtcacagcagcagtagcagcagcaacaacagtcaCAGCAGCTCTGGCTCCTCTTCACCCCAAGGCATTTGCATGTCATCGTCCAGTGCTGGAGGCGATGAgcatatgaaatatttatgcccTATCTGTGAAGTTGTCTCGGCCACGCCCCATGAGTTTACCAATCACATCCGATGTCATAATTATGCCAATGGCGATACCGAAAATTTCACCTGTCGTATTTGCTCCAAGgtACTATCCTCAGCTTCATCCTTGGATAGGCATGTCCTAGTCCATACGGGTGAACGTCCATTTAATTGTCGCTACTGTCACCTGACTTTCACCACAAATGGTAATATGCATCGTCATATGCGTACCCATAAGCAACATCAAACGGCTGCAGCAGGTGGCGGGGGTGGCGGTTCTTCATCCCTGACGGCACAGCAAAGacgtcagcaacagcagcagcaacaacaacagcagcagcaccagcaacagcagcagcaacaacaacagcagcagcaacaactgcaacagcaacaacaaaaccaaaagcaacagcaacaacattcaTTGGTCACTGATGGAAATTCTGGTAGCTATGAAAGTGATGCCAGTTGCTCCACAGATTTATCGAGTAATCAAAGCCAAAGCAGTCATAGCCACAGCCAAagtagcaataacaacaataataataataacaacaacaacaacaacaacaacaacaacattaaaacCACTAACAATAATCAAGAGGAAAGAATTAAGGAAGAGCAAATTGATTTGGAGGATGAGGATCAAGAATTAAATGAATCAATGGACGAATTGCCATTATTAAAGCAAAAACGTCGACCAAAGACCACCATCAATAACAATATaatagatgatgatgaaggtGGCAGAAGGAAGATTAGTAACAACGAAGATGATCCTGATGAGGATGATATTGagaatgatgacgatgatgataatgataatgaggAGGATCACCGTACAGAAGTGGAAGTATCTATTACTAGTACACCAGATGTGGCCGCTTTATTGGCGGGTGCCTCTAGACCAGGATCGCCTTCACCATCATTAATCAGTTGTCCCGTTTGCAATTTGGCCGAATTTGAAACCCTGCCCAGTTTATGCCAACATTTGGATCAACAACATTCTGATATTTTGGCCAAATGTCGTGAATGTGATGTCATCTTTTCCAGTCATAAGCAATTGCAAAAGCATTGTTGTCGGGGTTCATCTTCTACGGGTTTGCCACCTCTATTAAGAGCGAGTAGCTCACCATtgcatgctgatcaagaagaTGATGAAGAGGAGGACGAGCATCATGGACATGAGAAATTGCTAAAGAGAGTATCTACTCATCATGGtcacgatgatgatgacaatggcgatgatgatgatgataatgatgatggacAAGTTGAAAAGGAAGCCGAAGCAGAAGCCAAACAGCGTGACGATTTCTTTCATCATTTGTATTTGAAGAGTAAACCGGATGCCATGTCTGAGGATAATAACGAGTTGGTCACATCGCCACCATCACCTATTAAGCATGAACCGAATGATAGCAAAGATTTGGCTGATATACAAAGTATCCTCAATATGACCAGTTCGAGTTGTACATCCAGTTTTTTGCGCAACTTTGAGCAATCGGTTAATACACCCTGCTCATCGAGTCAATACAGTTTAGATGGACGGGATCAGGAGGAAGAGGCTCAAGATGTATTCACTTCCGAATTTCGTCGCATGAAATTACGAGGTGAATTTCCCTGTAAACTTTGCTCAACGGTTTTTCCCAATTTGCGTGCTCTCAAGGGGCATAATCGTGTTCATTTGGGAGAAGTTGGACCAGCGGGTCCCTTCCGTTGCAACATGTGCCCGTATACAGTCTGCGATAAGGCCGCCCTGGTCCGTCATATGCGTACCCATAATGGAGATCGTCCGTATGAATGTGCCGTATGCAATTATGCCTTCACCACAAAAGCAAATTGTGAGCGTCATTTAAGGAATCGTCATGGGAAGACAAGTCGGGATGATGTTAAACGGGCCATTGTCTATCATCCGGCCGAGGATGCCAGCTGCGGTGAGGGTGAGGGTAAAATCCGTATGGGTGAAGCGGATGAGAGCTATCGTTCGGCATCACCACCGCCAATGGAAACAGGGGCTCCATCCCAATTGAAGCACATGCTAATGAGTGAACCAATGCAAACagcacaacagcaacagcagcagcagcagcagccgccacTTAAAATTCAAGTTAAAAGCTTGGATCAATTGGTGGAGAAAACGACACCGTTAAAGACTGCACCATCGCCATCGATAAGTGCTATGGATCTCTCCATGGATGTGCTAGATCTCAGCAAGAAGCCATCTGCTGCTACATCTGTGCCATTGCCAATTTCTTCACCAGTTTCAACTGATTTGGCcgaacaacagcaacgtcagcagcagcagcagcaacaacaacagcaacagcagcaacaattacaactattggcccaacaacaactatttgGCCAGAATGATGCTGCATCACAATATATGCAGCAACTTTTTCGTAATTTTATGTTTCAACAATCGTCCGGATTTCCCTTTTTTGGCTTTATGAATCCACCGCCGCCACCTTCAAgcgcggcagcagcagcagcagcagcagttgcagGAGCAGCAGAGAAGTTGCCTCCTCCATCaccgcaacagcaacaaatgagTCCATCCAGTAATCGATTGGCCCTGCCACCATTATCCCTATCCGGTGGTCCAGTTAAAATGGTCATTAAGAATGGTGTCCTAATgccaaagcaaaagcaacgTCGCTATCGCACTGAGCGTCCCTTTGCCTGTGAACATTGCTCAGCCAGATTTACATTGCGTTCGAATATGGAGCGGCATGTTAAGCAGCAACATCCACAATTCTATGCCCAGCGTCAGAGGAGTGGACATCATGTGATGCGTGGTcgtggagcagcagcagctgcccaagccgcggcagcagcagctgcagcagcccAAGCGGCGGTACTAACAGCCACTCCGCatcaccatcagcagcagcaacagcaacaacagcagcagcaacaccatcatcatcatcaccatcaggGACATGGTCAAGGTTTGGTGGCACCCATCTCAGATCAAGTGAAATATGCCATATTGGCCCAACAACTTAAGGCTCATAAGAATACAGATCTACTGCAGCAGGCTCTTGCCCATGGATCGAGTAGTGTGGCAGCTTCATCGCATCTGATGAGTCTCAATTATGCTCTGGGAAATGGAAATTCGAATGGTAATGCCAATGGTCATTGTTTGACCATCGATGATGATGAACCAAAGCTAATTATAGATGAAGATGAGGCTGAAAATGAAGCCGAACCGGACGATGATTTCGAAgacgatgaggatgaggatgaagaggatgatgatgatgagacgGCAGCACCTCTCAATATGGATATGGAGAAAGCGGTAGAGGAAGAGAAACAGTCCCGTAAAGCTAACAAAGATTTACCCCAAACCCTAGAGACTTTGGCCAACAATGAGGCAGCCAAAAAGGTAGCCGAAACAATTTTGGAGCAGGCCATTAAAGCAGGTAAACCATTATCCATACCAGAAGTTGAGCCAGCTCCAGCAACAGTTGCTGCTTCCCAGCTACCCCATCAGCCACCATCTTCGATGAAATCTATGATTGCTCAAGTTGAATCCGTGGCCAAGTCGCTTAAAGATGTGGCCAGTTCACCATTTAACAAAGATGAATCTCCACTGTCGGATTTGGTGCCTGTATCCAAACTAGTGGATAATGCAACCAGTAATCAATCAATGCAAAGTTTCACCAGCTACTTTCGTCCCAGTGATGTGGCCAATCATATGGAACAGAGCGATGAGGAGGGACTCGTTGCCTCTGGCAGTGCCAGCGAGAGCAATAATTCCGGCACTGAAGATGTAaccagcagcagtagcagtggACAGGAGCCCAAGAAAAAGTCCGCTTACAGTCTGGCACCGAATCGTGTCTCCTGTCCCTACTGTCAGCGCATGTTCCCCTGGAGCAGCTCACTCAGAAGACACATTCTAACCCACACGGGACAGAAGCCCTTCAAATGCTCTCATTGCCCTTTACTCTTTACCACCAAAAGCAATTGTGATCGTCATTTGTTAAGGAAACATGGTAATGTCGAATCGGCCATGTCCGTATATGTCCCCACCGAGGATGTAAGTGAACCGATACCAGTACCAAAATCAGTGGAAGAGATTGAATTGGAGGAGCAAAGAAAACGCCAAGAGGCCGAAAAAGAGAAGGCCGAATTGGAACGGGAACGAGAACGAGAACGTGAAAGGGAATTGGAACGAGAGAGGGAAAAAGAGCGTGAGCGTGAACATGAGCGAGAATTGGAAATGGAGCGAGAGCAAAAGCTTTTGCAACAATTCACTGCCGCTGCTCAATTAACTCAGCAAATGGCTGTGGCAGCATCATCTTCGGCAGCAGCGGCACTTATTTCAGCGAGTAGCGAGTTGGCCAATGGCGATTTGCCCTTCAAGTGCCATTTGTGTGAATGTTCCTTTAGCGAGCGTTTACAATGCTTGGATCACATCAAACAAATGCATGCCCATGAATTTGCCCTGCTTTTGGCCAAAGGAGCCATTGAAACAGAAGAACCCACTCTTAATGCTAATCCAACAGCAGCTAATCAATCCGATGACGAGTCTTTGGGCATTGGCAATGGCCGTTCTGGTTCCGGTAAATATCCCGATTATAGCAATCGCAAAGTCATATGTGCCTTTTGTGTTCGTCGTTTCTGGTCCACCGAAGATTTGCGTCGTCATATGCGTACCCATTCGGGTGAGCGGCCATTTCAGTGCGAGATTTGCCTTAGAAAATTCACTCTAAAGCATAGCATGTTGCGGCATATGAAGAAACATAGTGGACGATCGCATAATGCTGGTGAAATGCAAGGTGGTTCTGATTGTTCCGATGATGAGCAAATTATGAtgactgcaacaacaacaaccacaccGCCACCCACTCCCCTGcctaataataacaataattgtcataccaataataataacaacaataataataataataataacaataataataaattgggTCTACGTCTCCCGAAACTGCATGAGCTACTGGATAAGGCCAACGAGTGGCGGGCCAGTCGCTTGGGCGAGCACAAAGAGAATCTGGGTGAAGCGGCGACTACTCCTGCAAGTGCAGCTGGAGCTGTGGCTGGTTCAACGGATCTCATTGGCAATCTATTGGGCATTACCGATCAGGgtatattgaataaattgcTCTCGTCCGCCGATGAGGCAGCCAAATTTCTGGGAGTGGACAAGTAA
Protein Sequence: MLATTTTTAATASTSTEMERQRRDSTTSESSLEHLDLGRTPKKLSSASGTLQPTSTPHNVTATTTTTSRKRKLRQQQHHHNQHGLLSLSEDDEDGEEESSSAAASTAVIVQQRPRHKQRRNGTVAAAASASIVMDSGADANSLRKKFRLNRSNSSSLLNGELSESGFVDGSTHSGYLMGNGNGSVTHSSNSASDAAAAAAAAASASAVSHSHSSSSSSNNSHSSSGSSSPQGICMSSSSAGGDEHMKYLCPICEVVSATPHEFTNHIRCHNYANGDTENFTCRICSKVLSSASSLDRHVLVHTGERPFNCRYCHLTFTTNGNMHRHMRTHKQHQTAAAGGGGGGSSSLTAQQRRQQQQQQQQQQQHQQQQQQQQQQQQQLQQQQQNQKQQQQHSLVTDGNSGSYESDASCSTDLSSNQSQSSHSHSQSSNNNNNNNNNNNNNNNNNIKTTNNNQEERIKEEQIDLEDEDQELNESMDELPLLKQKRRPKTTINNNIIDDDEGGRRKISNNEDDPDEDDIENDDDDDNDNEEDHRTEVEVSITSTPDVAALLAGASRPGSPSPSLISCPVCNLAEFETLPSLCQHLDQQHSDILAKCRECDVIFSSHKQLQKHCCRGSSSTGLPPLLRASSSPLHADQEDDEEEDEHHGHEKLLKRVSTHHGHDDDDNGDDDDDNDDGQVEKEAEAEAKQRDDFFHHLYLKSKPDAMSEDNNELVTSPPSPIKHEPNDSKDLADIQSILNMTSSSCTSSFLRNFEQSVNTPCSSSQYSLDGRDQEEEAQDVFTSEFRRMKLRGEFPCKLCSTVFPNLRALKGHNRVHLGEVGPAGPFRCNMCPYTVCDKAALVRHMRTHNGDRPYECAVCNYAFTTKANCERHLRNRHGKTSRDDVKRAIVYHPAEDASCGEGEGKIRMGEADESYRSASPPPMETGAPSQLKHMLMSEPMQTAQQQQQQQQQPPLKIQVKSLDQLVEKTTPLKTAPSPSISAMDLSMDVLDLSKKPSAATSVPLPISSPVSTDLAEQQQRQQQQQQQQQQQQQQLQLLAQQQLFGQNDAASQYMQQLFRNFMFQQSSGFPFFGFMNPPPPPSSAAAAAAAAVAGAAEKLPPPSPQQQQMSPSSNRLALPPLSLSGGPVKMVIKNGVLMPKQKQRRYRTERPFACEHCSARFTLRSNMERHVKQQHPQFYAQRQRSGHHVMRGRGAAAAAQAAAAAAAAAQAAVLTATPHHHQQQQQQQQQQQHHHHHHHQGHGQGLVAPISDQVKYAILAQQLKAHKNTDLLQQALAHGSSSVAASSHLMSLNYALGNGNSNGNANGHCLTIDDDEPKLIIDEDEAENEAEPDDDFEDDEDEDEEDDDDETAAPLNMDMEKAVEEEKQSRKANKDLPQTLETLANNEAAKKVAETILEQAIKAGKPLSIPEVEPAPATVAASQLPHQPPSSMKSMIAQVESVAKSLKDVASSPFNKDESPLSDLVPVSKLVDNATSNQSMQSFTSYFRPSDVANHMEQSDEEGLVASGSASESNNSGTEDVTSSSSSGQEPKKKSAYSLAPNRVSCPYCQRMFPWSSSLRRHILTHTGQKPFKCSHCPLLFTTKSNCDRHLLRKHGNVESAMSVYVPTEDVSEPIPVPKSVEEIELEEQRKRQEAEKEKAELERERERERERELEREREKEREREHERELEMEREQKLLQQFTAAAQLTQQMAVAASSSAAAALISASSELANGDLPFKCHLCECSFSERLQCLDHIKQMHAHEFALLLAKGAIETEEPTLNANPTAANQSDDESLGIGNGRSGSGKYPDYSNRKVICAFCVRRFWSTEDLRRHMRTHSGERPFQCEICLRKFTLKHSMLRHMKKHSGRSHNAGEMQGGSDCSDDEQIMMTATTTTTPPPTPLPNNNNNCHTNNNNNNNNNNNNNNNKLGLRLPKLHELLDKANEWRASRLGEHKENLGEAATTPASAAGAVAGSTDLIGNLLGITDQGILNKLLSSADEAAKFLGVDK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00483934;
90% Identity: iTF_00483934;
80% Identity: -