Basic Information

Insect: Drosophila austrosaltans
Gene Symbol: RREB1
Assembly: GCA_035045865.1
Location: JAWNOQ010000007.1:21539857-21546760[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 13 0.038 4.2 8.7 0.8 1 21 259 279 259 281 0.93

2 13 0.00035 0.04 15.1 0.2 1 23 291 313 291 313 0.98

3 13 8.5e-05 0.0095 17.0 7.3 1 23 319 341 319 341 0.98

4 13 4.3 4.9e+02 2.2 0.7 2 23 566 588 565 589 0.90

5 13 2.5 2.8e+02 3.0 6.2 2 19 595 612 595 614 0.97

6 13 0.0093 1 10.6 0.1 1 23 797 819 797 819 0.97

7 13 1.3e-05 0.0015 19.6 0.7 1 23 829 851 829 851 0.99

8 13 0.00087 0.098 13.9 2.0 1 23 857 880 857 880 0.97

9 13 0.0031 0.35 12.1 2.0 1 23 1153 1176 1153 1176 0.95

10 13 9e-05 0.01 16.9 0.3 2 23 1551 1572 1550 1572 0.97

11 13 0.15 17 6.8 6.3 1 23 1578 1601 1578 1601 0.97

12 13 0.0088 1 10.7 0.5 3 23 1810 1830 1808 1830 0.96

13 13 0.0014 0.16 13.2 4.8 1 23 1836 1858 1836 1858 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	13	0.038	4.2	8.7	0.8	1	21	259	279	259	281	0.93
2	13	0.00035	0.04	15.1	0.2	1	23	291	313	291	313	0.98
3	13	8.5e-05	0.0095	17.0	7.3	1	23	319	341	319	341	0.98
4	13	4.3	4.9e+02	2.2	0.7	2	23	566	588	565	589	0.90
5	13	2.5	2.8e+02	3.0	6.2	2	19	595	612	595	614	0.97
6	13	0.0093	1	10.6	0.1	1	23	797	819	797	819	0.97
7	13	1.3e-05	0.0015	19.6	0.7	1	23	829	851	829	851	0.99
8	13	0.00087	0.098	13.9	2.0	1	23	857	880	857	880	0.97
9	13	0.0031	0.35	12.1	2.0	1	23	1153	1176	1153	1176	0.95
10	13	9e-05	0.01	16.9	0.3	2	23	1551	1572	1550	1572	0.97
11	13	0.15	17	6.8	6.3	1	23	1578	1601	1578	1601	0.97
12	13	0.0088	1	10.7	0.5	3	23	1810	1830	1808	1830	0.96
13	13	0.0014	0.16	13.2	4.8	1	23	1836	1858	1836	1858	0.99

Sequence Information

Coding Sequence: ATGctagcaacaacagcatcatcagcagtagcagcagccgcagcagcagcaacatcaacagaaATGGAACGTCAACGCAGAGATTCCACAACCTCAGAATCCTCATTGGAACATCTTGATCTTGGACGCACACCAAAGAAATTAAGCAGCGCCAGCGGAACGCTGCAGCCAACCTCAACGCCACATAatgcatcaacaacaacaacaacagcagcagtaggaACAACGACATCGCGTAAACGTAAATTGcgccaacaacagcatcatcatcatcatcatcataatcagcATGGTTTACTCTCACTGTCCgaagatgatgaagatggAGAGGAGGAGTCATCATCTGCtgcagcatcaacaacagccGTTATAGTGCAGCAGCGCACACGCCATAAACAGCGACGCAACGGTAATGTTGCCGCCGCTGCCAGCGCCAGCATTGTAATGGACAGCGCTGCCGATGCCAATTCACTGCGCAAGAAATTTCGTTTAAatcgcagcaacagcagcagcctcCTTAACGGTGAACTATCCGAATCGGGATTTGTTGATGGGAGCACCCACAGTGGCTATCTTATGGGCAATGGCAGCAGCGTTGCTCATTCATCGAATTCTGCTGCTggcgctgccgctgctgccagTACATCTGCCGTTAGTCATagtcacagcagcagcagtagcagcagcaacaacagtcaCAGCAGCTCGGGCTCCTCATCCCCACAAGGCATTTGCATGTCATCGTCCAGTGCTGGCGGCGATGAgcatatgaaatatttatgccCCATCTGTGAGGTTGTCTCGGCCACGCCCCACGAGTTTACCAATCACATCCGATGTCATAATTATGCCAATGGCGATACCGAAAATTTCACCTGTCGCATTTGCTCCAAgGTTTTATCCTCAGCTTCATCCTTGGATAGGCATGTCCTTGTCCATACGGGTGAACGTCCCTTCAATTGTCGCTACTGTCACCTGACTTTCACCACAAATGGCAATATGCATCGTCATATGCGTACGCATAAGCAACATCAGACGGCAGCAGCAGGTGGCGGGGGTGGCGGTTCATCATCCCTAACGGCGCAACAAAGacgtcaacagcagcagcagcagcagcaacaacaacaacaacagcagcagcagcaacaacagcagcaacatcagcaacaacaacaacaacagcaacaacaaaagcaacagcagcaacattcaTTAGTTGCTGATGGAAATTCTGGGAGCTATGAAAGTGATGCCAGTTGCTCCACAGATATGTCAAGTAATCAAAGCCAAAGCAGTCATAGCCACAGCCAAagtagcaataacaacaacaataacaacattaAAACCACTAACAATAATCAGCAAGAAAGGATTAAGGAAGAGCAAATTGACTTGGAGGATGAGGAGCAAGAAGTTGCTGCCGCATCCATGGACGAGTTGCCATTGTTAAAGCAAAAACGTCGACTAAAGACAACCatcaataacaatataatagACGATGATGAAGCTAGACGGGAGAATGGAGATGATGCCGATGCTGATGAGGATGAGAATGaaaatgatgataataataatgatgaggaggaggaggatgaTCGCCGCACAGAAGTTGGAGTATCAATTACTAGTACACCAGATGTGGCCGCTTTGTTGGCAGGTGCCTCAAGACCAGGATCACCTTCACCCTCGCTAATCAGTTGTCCTGTCTGCAATTTGGCCGAATTTGAAACCCTGCCCAGTTTATGCCAACATTTGGATCAACATCATTCCGATATTTTGGCCAAATGTCGCGAATGTGAGGTGATCTTTTCCAGTCATAAGCAACTGCAAAAGCATTGCTGTCGGGGCTCATCGTCAACGGGATTGCCACCGCTGCTTAGAGCGAGTAGCTCACCATTGCATGCTGACCAACATGAGGATGATGAGGAGGAGGATGACGAGAATATCATTAGACATGAGAAGGTGCAGAAGAGAGTAGCTAATCATCatcacaataataataatattgacgacgatgatgatgatgtggatgAAGTAGGGGAAGGTGAAAAAGAAGCCGAAGCAGAAGCCAAACAGCGTGACGACTTCTTCCATCATCTGTATTTGAAGAGCAAACCTGAAGCCATGTCCGAGGATAACAATGAGTTGGCCACATCACCACCATCACCGATTAAGCATGAGCCAAATGATAGCAAAGATTTGGCAGATATACAAAGTATCCTCAATATGACCAGTTCGAGTTGTACATCCAGTTTTTTGCGTAACTTTGAGCAATCTGTCAATACGCCCTGCTCATCGAGTCAATACAGCCTGGATGGACGGGATCAGGAGGAGGAGGCCCAAGATGTATTCACTTCGGAATTTCGTCGCATGAAATTGCGTGGAGAATTCCCATGTAAACTCTGCTCAGCGGTTTTCCCCAATTTGCGTGCCCTCAAGGGCCATAATCGTGTCCATTTGGGTGAGGTGGGACCAGCGGGACCCTTCCGCTGCAACATGTGTCCATATGCTGTGTGCGACAAGGCCGCCCTGGTGCGTCATATGCGCACTCATAATGGAGATCGTCCGTATGAATGTGCCGTATGCAATTATGCCTTCACCACAAAGGCCAATTGTGAGCGCCATTTGAGGAATCGTCACGGGAAGACCAGTCGGGATGATGTCAAACGGGCCATAGTCTATCATCCGGCCGAGGATGCCAGCTGTGGTGAGGGTGAGGGTAAAATCCGTTTGGGTGAGGCCGATGAAAGTTATCGTTCGGCATCGCCACCGCCATTAGAAACTGCAGCTCCCTCCCAATTGAAGCACATGCTGATGAGTGAACCAATGCAAAcgccacagcaacaacagcaacagcagcagccgccaCTTAAAATTCAAGTTAAAAGCTTGGATCAATTGGTGGAGAAGACAACACCATTGAAGGCTGCACCATCGCCATCGATAAGCGCTATGGATCTCTCCATGGATGTCCTAGATCTCAGCAAGAAGCcatctgctgctgctacatCTGTGGCATTGCCAGTGCCTTCGCCAGTTTCTGCTGATTTGGCtgaacaacagcaacgccaacagcagcagcaacaacaacagcagcaacaactacaactattGGCACAGCAACAACTGTTTGGCCAAAATGATGCTGCATCCCAATATATGCAACAACTTTTTCGCAATCTTATGTTCCAACAATCATCCGGATTTCCTTTCTTTGGCTTCATGACGCCACCACAGCCACCACCGCCACCTTCTAGctcagcagcggcagcagcagcagcagcagcggccgAGAAGTTGCCACCACCATCaccgcaacagcaacagatgAGCCCCTCCAGCAATCGTTTGTCCCTGCCACCATTATCCCTTACCGGTGGCCCAGTCAAAATGGTCATTAAGAATGGTGTCCTAATGCCCAAGCAAAAGCAACGCCGCTATCGCACTGAGCGTCCCTTTGCCTGTGAACATTGCTCGGCCAGATTCACATTGCGTTCGAATATGGAGCGACATGTCAAGCAGCAACATCCGCAATTCTATGCCCAGCGTCAGCGAAGTGGACATCATGTGATGCGTGGTCGGGGAGCAGCAGCGGCTGCCCAAgctgcggcagcagcagctgctgcagcacAGGCGGCGGCACTTACAGCCACaccgcatcatcatcatcagcagcaacaacaacagcagcagcagcagcaacaacagtcgcaccatcatcatcaccatcaccatCAGGGACATGGTCAAGGTTTGGTGGCACCCATTTCGGATCAAGTGAAATATGCCATATTGGCCCAGCAATTGAAGGCCCACAAGAATACTGATCTGCTGCAGCAGGCTCTTGCCCATGGATCGAGCAGTGTGGCAGCATCTTCCCATCTGATGAACCTCAATTATGCTTTGgccaatggaaatggaaatgggaatGCCAATGGCCATTGTTTGACCATCGATGATGATGAACCAAAGCTAATTATTGATGAGGATGAGGCTGAAAATGAACCCGAACCTGATGATGATTTCGAAGACGATGAGGATGAAGATGAAGTGGATGATGAAGAAGAGGCAGCAGCTCTCAATATGGATATGGAGAAAGTAGTTGAGGTTGAGCAACCATCACGAAAAGCTAGCAAAGATTTGCCCCAAACCATAGAGAACTTGGCCACCAATGAGGTAGCCAAAAAGGTAGCCGAAACCATTTTGGAGCAGGCCATTAAAGCAGGTAAACCCGTATCCATACCAGAAGTTGAGCCAGCTTCGGTTtcagctgcagctgcagctTCTCTGCCCCATCAGCCGCCATCTTCGATGAAATCGATGATTGCTCAAGTTGAATCCGTGGCCAAGTCCCTTAAAGATGTGGCCAGTTCACCATTTAACAAAGATGAATCTCCATTGTCCGATTTGGTGCCAGTGTCCAAGCTGGTGGATAATGCAACCAGTAATCAATCGATGCAAAGTTTCACCAGCTATTTTCGTCCCAGCGATGTGGCCAATCATATGGAACAGAGCGATGAGGAGGGACTCGTTGCCTCCGGCAGTGCCAGCGAGAGCAACAATTCCGGCACCGAGGATGTcaccagcagcagtagcagtggCCAGGAACCCAAAAAGAAGTCCGCCTACAGTCTGGCCCCCAATCGTGTCTCCTGTCCCTACTGTCAGCGCATGTTCCCCTGGAGCAGCTCCCTCAGACGGCACATTCTAACGCACACGGGGCAGAAGCCCTTTAAGTGCTCCCATTGCCCATTACTCTTTACCACCAAAAGCAATTGTGATCGTCATTTGTTGAGGAAACATGGTAATGTCGAGTCGGCCATGTCCGTGTATGTCCCCACCGAGGATGTTAATGAGCCGATACCAGTACCAAAATCAGTGGAAGAGATTGAATTGGAAGAGCAAAGGAAGCGGCAGGAGgccgaaaaagaaaaggccGAATTGGAACGAGAACGCGAAAGGGAATTGGAACGAGAGCTGGAACGAGAGAGGGAAAAGGAGCGCGAGCGTGAACGTGAACGAGAATTGGAACTGGAGCGAGAGCAACAACTTATGCAACAATTGGCTGCCGCTGCTCAGTTAACTCAGCAAATGGCTGTGGCAGCTTCATcatcggcagcagcagcagcagcagttgctgCTTCAGCGAGTAGCGAGTTGGCCAATGGCGATTTGCCCTTCAAGTGCCATTTGTGTGAATGTTCCTTCAGTGAGCGTTTGCAATGCTTGGATCACATCAAGCAAATGCATGCCCATGAATTTGCCCTACTCCTGGCCAAGGGTGCCATTGAAACTGAGGAGCCCGCTCTAAATGCTAatccaacagcagcagctcctCAATCCGATGACGAATCATTGAGCGGCATTGGTAATGGCCGCGGTGCTGGTTCCGGTAAATATCCCGATTATAGCAATCGCAAAGTGATTTGTGCCTTTTGTGTTCGTCGTTTCTGGTCCACCGAGGATCTGCGTCGTCATATGCGCACCCATTCGGGTGAGCGGCCATTTCAGTGTGAGATTTGCCTTAGAAAATTCACCCTAAAGCACAGCATGTTGCGGCACATGAAGAAGCATAGTGGAAGATCCCATAATGCTGGTGAAATGCAAGgtggatccgattgttccgATGATGAGCAAATTATGATGACTGCAACCTCAGCGACCACACCGCCACCCACTACCCTGcccaataataacaacaattgtcataccaataataacaacaacaataacaacaacaacaataacaataataataacaataacaataataaattggGTCTACGTTTGCCAAAATTGCATGAACTACTGGACAAGGCCAACGAGTGGCGAGCCAGTCGCCTGGGCGAGCACAAAGAGAATCTGGGTGAAGCGGCGGCAACGACACCAACAAGTGCAACTGGAGCTGTTGTGGCTGGTTCAACGGATCTCATTGGCAATCTGTTGGGCATTAGCGATCAGGGTATATTGAACAAGTTGCTCTCGTCAGCGGATGAGGCAGCCAAATTGCTGGGAGTGGACAAGTAA
Protein Sequence: MLATTASSAVAAAAAAATSTEMERQRRDSTTSESSLEHLDLGRTPKKLSSASGTLQPTSTPHNASTTTTTAAVGTTTSRKRKLRQQQHHHHHHHNQHGLLSLSEDDEDGEEESSSAAASTTAVIVQQRTRHKQRRNGNVAAAASASIVMDSAADANSLRKKFRLNRSNSSSLLNGELSESGFVDGSTHSGYLMGNGSSVAHSSNSAAGAAAAASTSAVSHSHSSSSSSSNNSHSSSGSSSPQGICMSSSSAGGDEHMKYLCPICEVVSATPHEFTNHIRCHNYANGDTENFTCRICSKVLSSASSLDRHVLVHTGERPFNCRYCHLTFTTNGNMHRHMRTHKQHQTAAAGGGGGGSSSLTAQQRRQQQQQQQQQQQQQQQQQQQQQHQQQQQQQQQQKQQQQHSLVADGNSGSYESDASCSTDMSSNQSQSSHSHSQSSNNNNNNNIKTTNNNQQERIKEEQIDLEDEEQEVAAASMDELPLLKQKRRLKTTINNNIIDDDEARRENGDDADADEDENENDDNNNDEEEEDDRRTEVGVSITSTPDVAALLAGASRPGSPSPSLISCPVCNLAEFETLPSLCQHLDQHHSDILAKCRECEVIFSSHKQLQKHCCRGSSSTGLPPLLRASSSPLHADQHEDDEEEDDENIIRHEKVQKRVANHHHNNNNIDDDDDDVDEVGEGEKEAEAEAKQRDDFFHHLYLKSKPEAMSEDNNELATSPPSPIKHEPNDSKDLADIQSILNMTSSSCTSSFLRNFEQSVNTPCSSSQYSLDGRDQEEEAQDVFTSEFRRMKLRGEFPCKLCSAVFPNLRALKGHNRVHLGEVGPAGPFRCNMCPYAVCDKAALVRHMRTHNGDRPYECAVCNYAFTTKANCERHLRNRHGKTSRDDVKRAIVYHPAEDASCGEGEGKIRLGEADESYRSASPPPLETAAPSQLKHMLMSEPMQTPQQQQQQQQPPLKIQVKSLDQLVEKTTPLKAAPSPSISAMDLSMDVLDLSKKPSAAATSVALPVPSPVSADLAEQQQRQQQQQQQQQQQLQLLAQQQLFGQNDAASQYMQQLFRNLMFQQSSGFPFFGFMTPPQPPPPPSSSAAAAAAAAAAEKLPPPSPQQQQMSPSSNRLSLPPLSLTGGPVKMVIKNGVLMPKQKQRRYRTERPFACEHCSARFTLRSNMERHVKQQHPQFYAQRQRSGHHVMRGRGAAAAAQAAAAAAAAAQAAALTATPHHHHQQQQQQQQQQQQQSHHHHHHHHQGHGQGLVAPISDQVKYAILAQQLKAHKNTDLLQQALAHGSSSVAASSHLMNLNYALANGNGNGNANGHCLTIDDDEPKLIIDEDEAENEPEPDDDFEDDEDEDEVDDEEEAAALNMDMEKVVEVEQPSRKASKDLPQTIENLATNEVAKKVAETILEQAIKAGKPVSIPEVEPASVSAAAAASLPHQPPSSMKSMIAQVESVAKSLKDVASSPFNKDESPLSDLVPVSKLVDNATSNQSMQSFTSYFRPSDVANHMEQSDEEGLVASGSASESNNSGTEDVTSSSSSGQEPKKKSAYSLAPNRVSCPYCQRMFPWSSSLRRHILTHTGQKPFKCSHCPLLFTTKSNCDRHLLRKHGNVESAMSVYVPTEDVNEPIPVPKSVEEIELEEQRKRQEAEKEKAELERERERELERELEREREKERERERERELELEREQQLMQQLAAAAQLTQQMAVAASSSAAAAAAVAASASSELANGDLPFKCHLCECSFSERLQCLDHIKQMHAHEFALLLAKGAIETEEPALNANPTAAAPQSDDESLSGIGNGRGAGSGKYPDYSNRKVICAFCVRRFWSTEDLRRHMRTHSGERPFQCEICLRKFTLKHSMLRHMKKHSGRSHNAGEMQGGSDCSDDEQIMMTATSATTPPPTTLPNNNNNCHTNNNNNNNNNNNNNNNNNNNNKLGLRLPKLHELLDKANEWRASRLGEHKENLGEAAATTPTSATGAVVAGSTDLIGNLLGISDQGILNKLLSSADEAAKLLGVDK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00501276;
90% Identity: iTF_00501276;
80% Identity: -