Basic Information

Insect: Drosophila emarginata
Gene Symbol: -
Assembly: GCA_037075365.1
Location: JBAMCD010000324.1:4738459-4743490[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 0.00022 0.019 15.8 0.8 1 23 147 169 147 169 0.97

2 15 1.4 1.2e+02 3.8 1.7 1 23 175 198 175 198 0.90

3 15 0.00021 0.019 15.8 2.5 1 23 368 390 368 390 0.98

4 15 1.8 1.5e+02 3.5 2.9 1 23 396 419 396 419 0.95

5 15 1.2 1e+02 4.0 1.6 1 23 437 460 437 460 0.91

6 15 0.0012 0.1 13.4 1.9 3 23 759 779 758 779 0.92

7 15 0.048 4.2 8.4 1.4 1 23 785 808 785 808 0.98

8 15 0.4 35 5.5 1.4 2 23 845 866 844 867 0.93

9 15 0.0042 0.37 11.7 0.8 1 23 888 911 888 911 0.97

10 15 0.002 0.18 12.7 0.3 1 23 1100 1123 1100 1123 0.90

11 15 0.015 1.3 10.0 5.2 1 23 1135 1157 1135 1157 0.98

12 15 1.7e-05 0.0015 19.2 3.6 1 23 1162 1185 1162 1185 0.98

13 15 0.0018 0.16 12.9 4.4 1 23 1195 1220 1195 1220 0.95

14 15 0.0016 0.14 13.0 1.3 1 23 1225 1247 1225 1247 0.97

15 15 4.1e-05 0.0036 18.1 0.8 1 23 1254 1277 1254 1278 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	0.00022	0.019	15.8	0.8	1	23	147	169	147	169	0.97
2	15	1.4	1.2e+02	3.8	1.7	1	23	175	198	175	198	0.90
3	15	0.00021	0.019	15.8	2.5	1	23	368	390	368	390	0.98
4	15	1.8	1.5e+02	3.5	2.9	1	23	396	419	396	419	0.95
5	15	1.2	1e+02	4.0	1.6	1	23	437	460	437	460	0.91
6	15	0.0012	0.1	13.4	1.9	3	23	759	779	758	779	0.92
7	15	0.048	4.2	8.4	1.4	1	23	785	808	785	808	0.98
8	15	0.4	35	5.5	1.4	2	23	845	866	844	867	0.93
9	15	0.0042	0.37	11.7	0.8	1	23	888	911	888	911	0.97
10	15	0.002	0.18	12.7	0.3	1	23	1100	1123	1100	1123	0.90
11	15	0.015	1.3	10.0	5.2	1	23	1135	1157	1135	1157	0.98
12	15	1.7e-05	0.0015	19.2	3.6	1	23	1162	1185	1162	1185	0.98
13	15	0.0018	0.16	12.9	4.4	1	23	1195	1220	1195	1220	0.95
14	15	0.0016	0.14	13.0	1.3	1	23	1225	1247	1225	1247	0.97
15	15	4.1e-05	0.0036	18.1	0.8	1	23	1254	1277	1254	1278	0.96

Sequence Information

Coding Sequence: ATGGCTATGCCAAGTcaaatgaatagaaaaagttACCAAACGGCAAAGGCGAAAGTCGAGCccaatataaattacaaatacgCTTGTCGCTGCTGTCTCAAATCGGACGCGGAGTTTGTTAATCTGGATACATTGACGGTGGCGCGGAATCTAGATCCAAGTGAAGCGTCTGACCAAATACCATTAATAAGATGTCTGCTCTTTTGCATACACGCGGAAAATATTTCCGAATTGCCTCGATTAATTTGCATTGATTGTAGCAAGAGTTTGCAAATTGCCtattattttcttcaaaaTGCTCTGCGTGCCCATGATATCCTTTGTCGCAAACTGTGTCCAGACAAGTCAACAAATTCGCAATTTAATGCGCTTTTCAATGGCAATATTAGTCGTGAGaaAGCGCCAACAAAAACTCCACTCGGTAAAACCGGAGTTCGTCATGAGTGTAAAATTTGCGGTACCATTGTCTACAATAGAATGGAACTAAAACAGCATATACGTCTGCACCGAGACGCAGTTGCTCATAATTGCACACTCTGCAGTTTCGTCACAGTGAAGCAGCGCCAATTGGTGGATCATTATAGTTTTGTCCACCAGTTTACTACGGCACAGGCCGAGGAGCGGATTAACTCCGAGAATACTATTACAGAGCAACGTGACGAGAATCAACAAGAAGATCGTAAAGTATGCACTCTGGAAGATCTCGAATTGCTTATACCTACTGTGCTTAGACCAGAGGATTATGCGCATCCCAAAATTGAATACGACATTAATAATCAATTGGACGCTCCTTCAACGAGTAAGgaatcaaatggcaataatattAGCATTGGTACGGAATTTCTTGTCTTGCCAGACGGATCGCTCCAACAACTAAATGGTGCCGGAGTTCTTATTGAGTATATCGATGACAGCAAGAGGAATATCCCACCAACTGGTAATTTAAATCTACAAAGTCTTCTGGGCAGCGATGACGTAGACACTGCTCCAATGGATATAGATATTAATGAGCTGATTGTAGACGAAACCtcatttccaaaaataaacgcCAAACCAAAGTCAGGGAAAATTGCATTATCTAGTTCACCTTCCACATTTAAGCACAAATGCAAGCTTTGTACAAAAGCATTTCCCACCTTGGCTCGACTAAAATCTCATCAATTAACCCACAGCCatttaccAAAATTCCACTGTGACCAGTGTAGATACTACTCGTTGAGGAGCTCTGATCTTGCTTATCACTATAGAACAGTCCACAGCAAACAGGAGAATGAAAAGACAATACAGCCCGTAGATGATTCGCGTATCTTTTCCTGTGATCTGTGTTTGTTCGAGACCAGGAACTCACGCACACTACGTGACCACTACACTGATAAGCACTTGGTTCGCCCCACAGAGGTGCAGTTGCGTCCAAGTTGGACCGCTGATATGGAAGCGCTGGCGAGTACGGTAGTTAGTACCAAAAGATCAGCTCCTACCAGCGAGAATGTATCTAATCTGGTCTCTAATCATAAGCAAGAGACTTTTACTCCATTGGACATTAAATATCCTGATACAGGAATAATGCCCCAAGATACCGTCACAGATATTATGCAACAGCcacaggcaacaacaacagcaacaattacaCCAATGGGTGATATTAGTGTGGTTGTGGATGCCACGCCATTGTTCTTTGGAAATGGCACCGAAGCAGCTGACACTTCGTCAccacaaccaacaacaattccTCTTATTGTTGACAGCAATATCAATGAAAgcaacagcgacaacaacaacttttcAGCATTTCCAGAAATCTCGGCCAGCCACAATCTGGAATCATTAGTTGAGCCACCAATGCCGGCGATGCCCAACCAGAATCTTCCGACGATGTCGAATCCAAGTCTACCAACAACTTCAACCAATACAAATACGTTAATGTTTGGCGATATGCAAGACTTTATAGATAATACGGATGTGGCTGCCATATGCACAATACCAGCTGATGATATGCCCGTTGTCGATGGCGATGATATTGTTATtgataacaataatattaGTCTAGATTTCGATGCGGAAAATCTCTTTGAGGATTTCGAGGAGGACGAAGAGGAGGCAGTTGCTGCTGAAAATGAGGAGGGGGAGGTGGATGAGGAAGAGGACGATGCCgaaaatgatgatgagaatgatAACAATGATGCGGCAGCTGATCAGAATCTATTATTGACTAGTGATGACGACGATGTCGATGACTTTGATGATGAGCAGTCGAAGCATTTGCAGAAACCATATTGCATTTActgcaacaaaaagtttacTAGCCAATATAAGTTTGAGAATCATATGTTTGTCCATCGGGGTCTAGCACCCTATCGTTGTGAGCTCTGTACGAATCTTTACAATATGAAACGTCTACTCATCAGACATTATAAGACCGTACATAAACGGATGCCCACGCGAGATATGGTCCAGGCAAAGGGCGAGAAGATATCTGTGGCTCGTTCAAATAAGGAGACTATCCAGACCGATGTTAATAAAAATCCAATGCTAATGTGCGCCAAATGTCCATTTGAGTGTGAGTCGGAGGCAGAGATGAGAAAGCATTTAAATGCTCACCATGGCATAAATGATGGTGTTTCCGCACACGCCAATGAGGTATTCATCATACGCAAATTACCATTTGAGTGTCCCCGTTGCATACGTTCGTTTGCTGCGAAACGAACGCTAACACGTCATTTGCAACGTAGCCATTTGGTGGATACCATAATTGAGGTAACAGAAACAACCACCAGCAATACAGTGTCATCGACCAATGCTGAAGATACCGGAAATAAGGAGATTGCCATGATGATATCCCCGTCGGTGTTACCTGAAATTGATGGTGGCGAATGCGAAACGCGCAACAAAGACGATAGAGATGAAGCAGCAGGAATACTGAAGCAGGAAGCTGATGTGGTGGCATCAGTGGTAGATAATGAAAATCCGATAAACACTTCGGCTGCAAATTCTGCTGCAGAATCAACTACAGCAGCGCCAGCACCTTCGCCAACAACAGCATCGTCATCCTCAACACTTTTCCCTACTCCCACGCCCTTTGATTTTGACTATGATTTTATGGGTGACGCAGCCAACTCCACGCCTAGCACCAGcactaacaacaataataataacaacagtaCCGCTGATGGTTACACAAACGAAGCGACTGTGATTCCAAGCCATATTCTCAATGGGAGCGATAAGCTATTAACTGCTGCCACAATGGAGCCATCCCCCATAAAAAATGGACGATCGCGCCTTCCACGCACTCCAATCTATGTGTGCAAATTGTGCAATAAGACATTCGATGAACTAGGCAAATTAGTGAAACATGAAGCCGAGCAGCATTCTAGCAGTGAACCACGTCGCGTTGTCTTCCAGCACAAGTGTTCCATTTGCAATTCAACATTTCGGACATTGACCTTGCTTAAGTTCCATATGAAACGGCATTTGGCACGTAAATTTCAATGCAGTCGTTGTTCAAAATCCTTTAACAGAAGACAAGAAATGCAGCGACACATGTTGACCAAGCATGAAAAGCAGGATAGCAAAGAAAAGTCCTTCAGATGCTCTTTGGACGGGTGTAAAAAAACCTTTAACTACAAACATCACATGGTCCGTCATCAAAATGCGGTACATCTCAAGATCCGGCACATTTGTAATCTTTGTGGCGATGATTTAAAAACCAGTTTTAACCTAAGGAGTCATATGCGCGTTCACAGTGGCAATGGAAAGTCGTACAAATGTCCCAATTGCGATCGATCGTATGTGCGGCGCGGACCACTTCAGCAGCATGCTCGTCAGGCTCATCACATTGAGTTTACTGATAGTGACTGGCCCCAAATGTTATGCAATAATATATGCTCCAACAATTCCCTAAATAAAAAAGTCTCTGCGCGAAAAAACAAGTCCTCAGCAAAAGAACAGGACAAGaattaa
Protein Sequence: MAMPSQMNRKSYQTAKAKVEPNINYKYACRCCLKSDAEFVNLDTLTVARNLDPSEASDQIPLIRCLLFCIHAENISELPRLICIDCSKSLQIAYYFLQNALRAHDILCRKLCPDKSTNSQFNALFNGNISREKAPTKTPLGKTGVRHECKICGTIVYNRMELKQHIRLHRDAVAHNCTLCSFVTVKQRQLVDHYSFVHQFTTAQAEERINSENTITEQRDENQQEDRKVCTLEDLELLIPTVLRPEDYAHPKIEYDINNQLDAPSTSKESNGNNISIGTEFLVLPDGSLQQLNGAGVLIEYIDDSKRNIPPTGNLNLQSLLGSDDVDTAPMDIDINELIVDETSFPKINAKPKSGKIALSSSPSTFKHKCKLCTKAFPTLARLKSHQLTHSHLPKFHCDQCRYYSLRSSDLAYHYRTVHSKQENEKTIQPVDDSRIFSCDLCLFETRNSRTLRDHYTDKHLVRPTEVQLRPSWTADMEALASTVVSTKRSAPTSENVSNLVSNHKQETFTPLDIKYPDTGIMPQDTVTDIMQQPQATTTATITPMGDISVVVDATPLFFGNGTEAADTSSPQPTTIPLIVDSNINESNSDNNNFSAFPEISASHNLESLVEPPMPAMPNQNLPTMSNPSLPTTSTNTNTLMFGDMQDFIDNTDVAAICTIPADDMPVVDGDDIVIDNNNISLDFDAENLFEDFEEDEEEAVAAENEEGEVDEEEDDAENDDENDNNDAAADQNLLLTSDDDDVDDFDDEQSKHLQKPYCIYCNKKFTSQYKFENHMFVHRGLAPYRCELCTNLYNMKRLLIRHYKTVHKRMPTRDMVQAKGEKISVARSNKETIQTDVNKNPMLMCAKCPFECESEAEMRKHLNAHHGINDGVSAHANEVFIIRKLPFECPRCIRSFAAKRTLTRHLQRSHLVDTIIEVTETTTSNTVSSTNAEDTGNKEIAMMISPSVLPEIDGGECETRNKDDRDEAAGILKQEADVVASVVDNENPINTSAANSAAESTTAAPAPSPTTASSSSTLFPTPTPFDFDYDFMGDAANSTPSTSTNNNNNNNSTADGYTNEATVIPSHILNGSDKLLTAATMEPSPIKNGRSRLPRTPIYVCKLCNKTFDELGKLVKHEAEQHSSSEPRRVVFQHKCSICNSTFRTLTLLKFHMKRHLARKFQCSRCSKSFNRRQEMQRHMLTKHEKQDSKEKSFRCSLDGCKKTFNYKHHMVRHQNAVHLKIRHICNLCGDDLKTSFNLRSHMRVHSGNGKSYKCPNCDRSYVRRGPLQQHARQAHHIEFTDSDWPQMLCNNICSNNSLNKKVSARKNKSSAKEQDKN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00577985; iTF_00483916; iTF_00591168; iTF_00556031;
90% Identity: -
80% Identity: -