Basic Information

Insect: Drosophila emarginata
Gene Symbol: hang
Assembly: GCA_037075365.1
Location: JBAMCD010000152.1:13467777-13480422[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 19 0.35 31 5.7 1.0 3 23 558 579 557 579 0.93

2 19 0.26 23 6.1 3.5 3 22 683 702 681 702 0.89

3 19 0.00076 0.067 14.1 3.3 1 22 798 819 798 821 0.90

4 19 0.088 7.7 7.6 0.1 2 21 833 852 832 853 0.93

5 19 0.00088 0.078 13.9 0.2 2 23 985 1007 984 1007 0.95

6 19 0.0025 0.22 12.4 0.1 1 23 1015 1038 1015 1038 0.96

7 19 2.1e-05 0.0018 19.0 0.1 2 23 1125 1146 1124 1146 0.97

8 19 0.00037 0.032 15.1 2.9 2 23 1238 1260 1237 1260 0.97

9 19 0.029 2.5 9.1 0.2 2 23 1269 1291 1268 1291 0.95

10 19 0.0015 0.13 13.1 0.1 1 23 1304 1327 1304 1327 0.97

11 19 0.00016 0.014 16.2 1.1 1 23 1383 1405 1383 1405 0.99

12 19 0.0025 0.22 12.4 0.9 1 23 1413 1436 1413 1436 0.96

13 19 0.55 48 5.1 1.5 2 20 1444 1462 1444 1462 0.96

14 19 0.00011 0.0093 16.7 0.2 3 23 1562 1582 1561 1582 0.98

15 19 0.0064 0.56 11.1 0.1 1 23 1617 1639 1617 1639 0.97

16 19 0.00077 0.067 14.0 0.7 2 23 1724 1746 1723 1746 0.93

17 19 1.5 1.3e+02 3.7 0.1 2 20 1766 1784 1765 1786 0.91

18 19 0.0082 0.71 10.8 0.3 3 23 1801 1821 1801 1821 0.98

19 19 4.8e-05 0.0042 17.8 2.3 1 23 2171 2193 2171 2193 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	19	0.35	31	5.7	1.0	3	23	558	579	557	579	0.93
2	19	0.26	23	6.1	3.5	3	22	683	702	681	702	0.89
3	19	0.00076	0.067	14.1	3.3	1	22	798	819	798	821	0.90
4	19	0.088	7.7	7.6	0.1	2	21	833	852	832	853	0.93
5	19	0.00088	0.078	13.9	0.2	2	23	985	1007	984	1007	0.95
6	19	0.0025	0.22	12.4	0.1	1	23	1015	1038	1015	1038	0.96
7	19	2.1e-05	0.0018	19.0	0.1	2	23	1125	1146	1124	1146	0.97
8	19	0.00037	0.032	15.1	2.9	2	23	1238	1260	1237	1260	0.97
9	19	0.029	2.5	9.1	0.2	2	23	1269	1291	1268	1291	0.95
10	19	0.0015	0.13	13.1	0.1	1	23	1304	1327	1304	1327	0.97
11	19	0.00016	0.014	16.2	1.1	1	23	1383	1405	1383	1405	0.99
12	19	0.0025	0.22	12.4	0.9	1	23	1413	1436	1413	1436	0.96
13	19	0.55	48	5.1	1.5	2	20	1444	1462	1444	1462	0.96
14	19	0.00011	0.0093	16.7	0.2	3	23	1562	1582	1561	1582	0.98
15	19	0.0064	0.56	11.1	0.1	1	23	1617	1639	1617	1639	0.97
16	19	0.00077	0.067	14.0	0.7	2	23	1724	1746	1723	1746	0.93
17	19	1.5	1.3e+02	3.7	0.1	2	20	1766	1784	1765	1786	0.91
18	19	0.0082	0.71	10.8	0.3	3	23	1801	1821	1801	1821	0.98
19	19	4.8e-05	0.0042	17.8	2.3	1	23	2171	2193	2171	2193	0.99

Sequence Information

Coding Sequence: ATGTGTGACACAGCGATAACGGTAAATTctacagcaacaataacatcaACAGGAGCAACACCGAATGCATCTGGACCCCAAATAGCAGCTACAATTATAGCTGCAGCTACAGGCACtgctacaaaaaaagaaccacAGCGAACGCCACAAAATTGTTGTCGCCTCTGCATTGCTCCGGCTACAGAGTGTATTTCGATCATCAATAGCTATGCAGCCGATAAGGAGCCGCTGACCACCAAAATCTATAATTGCGTCAATATCAAGaTCACATCTCAGGATCGTTTATCACAACAGATTTGTCATGCTTGCATTAGCTATCTGAATTCATGGCAAAGTTTCAAAAATCGCTGCCTTAGCTCACAGTCTAAGCAGCGTCAATGGTTGGAGACGACAACGACGCCGCCGACCGCGACAAGTAAAAGCAAACTTCTGAACTATTTGGACTTAAACAGTGCTGAAAATGGAACTGGAACAGGATCGGATAACCAGTTGGCGGCGGAGAATGAAGCAATTGTTGTCGGCAGCAGCGATATGGTGTCCGATGAAGCGGCGGACAAGTCCACTACCTCAGCATCAtctgcagcagcggcagcaacaacagcagcattgACAGCCAATATATTGGATGGAATACCAGCGCTGAAGAAACGCAAATCTTTAACAGTCTATGTGAGTccaaaacagcagcagcaacaacatcaactgcaacaactgcaacagcaacagcagcatcatttgcaactgcagcaacagcatcagcagcaacaattgcagccAGCCAAATTGACAGGCGGTTGGGCGTctggtggtagtggtggtgttgttggtgttggtggtgaGACACTTATTGTGGAAGTGATGCCGCCAGCAACGACAATTGCGACATGCTCCTCTTCCTCCTATACTTCCTCTTCCCAATATCAATCCCAGTCCCAATTGCAGCGACATCACCAGCATCAGCAACCATATCgtaaacaccaacaacaaagaagCAAGCGCCAGACCCAATATCAATATACCCCCAGACGTTCACGTCCGCAAGGAAGACGTGCTCCTGGTCATCCAATTCCATTTACTACCCAAGCTCCTACAATATCGATTAATTCCGCTGCCCATACGGCCACGcgcaaattgaaatcaaaaatgtatttaccATTGGATATAACAGTACCATCGCCTCCAATTCATGTTGCCGGTACGGCTCCTCATCCCCATCCTCATCCTCCTCAACCCCCTTCCGTGACTGCTACTGCTAGTTCGTCACTTGGTAGTGTCCTACCGCTACCACCACCAAAGCCTCAGTCAATGCCATATGGCCATATGGCCGTGGCCACCACATCAACATACTCGACGACGTCGACAACGCCGACTCCGATACCGACTTCGACTCCGCTGCTTATGCCACCTCTGCCTGCTGTGCCCATCAAAGATGAGCCTATAGATGACACCGATGATGACTATCAGATGAAGTCCATAGACGAATCCATAGATGATATGGTGGATCCCACAATGTTCCTAGAGCGTTCGGAGCTTGAAGGCGATGTGCCATTAATGACTTCGGATTATGATTATACAGCCCAGCATGGTGTTACGGCTGCTGTGGCGGCCGCCTCGCTACCAGCCAGCGCTGTTGCGAATGTGGCAGCTGCTGGTGATTCAAAGGTGGCCAGTTGTCGGGCATGCAGCCTACAGTTTTCCACCAGAGCCAATGCCCGCCGTCATGAGCGTAATCTGCATCCGAATCTCTTTCAATTGTCTACCGATTCGCCCAATAATACACCAGTTACAAAACCAACTCCAGCTCTAGCTGCCGCCTTGGAAATCCAACgggcggctgctgctgctgccacagcCGAGGCAAATCGTTCCGGTGGGAATATGTCCACACAAAAGTATCGTCAGGTGGTTATGAATGCCTTTATCAAATGTGAAGCCGGTGGCTATGACTATGACAATCCCGAGCAATATCAGCCTCTATTGAGTCGagataaaattgaatttattgaaCAGAATGCTGAATTTCTCGAGCAGTATCAGACAATGACCTGTCGCTGTTGCAACAAATTCTTCAGCACctataaaaatttcatggCCCATGTGCGAAAGAAATATCCATTGTTGCCGCGAAATCTTTGCTTTAACTGCCTTAAAATGAATGATTCGAAGGCATTGTTCATCTCGCATCTGAAGAAGCGTAACTGCATCAATCTGTATAGAGTGATGAATGCCTTAAATAATAAGCAAAATGATGGAATAGTACCAGTTGCTTCTTCTCCAGCTATTGTTGTGCCAGCAACAGTGTCGGCTGTCTCGGTGTcgagtacaacaacaacaactacttcagATCGGCCAGAGAAATTGCGGGCCAAGGAGCTACTGGTCAATAAGCTCTACGAATGCAAACTCTGTCCAAAAGGTTTCCGCACCAAACATGAATTCCGCACCCATGTTTATGACAAGCATGCAGATGTTCAGCGGAAGGATAATAATTCCATTCAATGCAGTTTCTGTGGTCTGGACTTTGCCGATCCTGTGGATAGACGGCGTCACTATAACAACATGGACTGCATTGTCCGTCTACGTTGCATGACCTGTGATGCCAAATTAGAGACGCATCAGCGATTCCTCGATCATGTATATCAGGATCATTTGGGCGGCCTGAGCAGTGATAATGCCTCATCGACGACTGTCAGTGGTGCAACTGTGGACAATTCACATTCACCTGGAAAAAAGAGTCTGTTAGGTGCTTTGGGCATAGGATCGGCAGATGAATCTCGGAGTGCCACTGCCCCCCCACCGCTAAACACATCTACACCAAAGCCAGTCGGAGGAGGATCATCATCAGCTGCGTCAACAACATCTGCTAGTGGTGGCTTATTAGGCGGTAGTACCTCAGTTAGTCGCGATCGTGATGGAGCACCAAAGTCTCAATATTTCTCTCGGATGCCCCAGGTCTGTCCCATTTGTGGCCAGCAAtataacaactacaacaatgtGCTCCGACACATGGAATCGAAGCATCCCAATAAACTGCCAGAAACGTACAAATGTGTACGATGCGGTTTGGGCTATCCACGAATCTCGTATCTGCGCGAGCACATGATAAATGTCCATGGCGTTGATAAAAATCGCCATTCGGGCGGATTTGAGTATATTGTTAATGCGGATGCCGTTAAACTGGCCGATGGCAGTACTCCGAATGTCTATACGGGCCGATATGATTATGTGATGAAGGATCTGATGTCGATAACAAATGGTGGGACCCTCGatgacgatgacgaggAGACAAGCGGCAGTGTGGCCAAGAAGATTCGTCTAGACGATAGCAGTAATAATAGCAGTCTGATGGGCATGGCGGCTACACAGCAGAAGGAGTGTCCCATCTGCAATGCGGTATTCAGCAACAACATTGGTCTATCGAATCATATGCGTTCCCATTATACAGCCTCAGCGAATGCATCTGCTTCGGCGAATGCCTCGGGATCGTCCGCCTCATCCAGCACAAATGCTGCATTGGCTGCAGCCAATCGCATTACACCCAAATCCCTGACTATAACAGCAGCTCCTCCAATCACAGCGGATGGAGCACAAACAGTGCCACATAAAAAGGAGTCGGCAACTatctcttcatcatcatcggcaCCTCAAGTTCAAGCGATACAGTTTCGCCGCAGTTTGGATCAGGCAGCCGATCGTCGGTTTCGGCGAATGCGTTGCCGTATCTGCCAGCGACGCTTCAGTTCCAAAAAATCGTATCGTTATCACATGCTCACCGATCATCAAGTCCAGAATGTTCAgtttataaaatgcaaattgtgtaATGCCGAATTTGCCTACGAGAAGGGGCTAAAAGTGCATCTATTTAAGGTGCATGGCAAGGCTATCAAGGATGAGATGATAATTAAGCAATTTGAATGCGAAATTTGCTCTATTGTCTATAGCTCGGAATTGGAATTACAGCAGCATAAGCGCAGTGTCCATGAGTTGGCTACAGCTTCATCATCagcagctgcaacaacaactatatcGTCATCGGcagtaaaagcaacaacaacaacatcatcatcatcaggcgAAATAACTGGAACAACACCGGGAATCGGTAACAACAATGGGGCTAGTTCAGTACCCGCACCTCTTTACTGGTATCAATGCAAATATTGTCCATCCAATTTCAATACCAATAAAAAGTTGGCCATTCACATCAATTCCCATGATGAATTCGATTCCAATGATTATTCGTGCAAGGATTGCGGCAATGTCTACAGTGGAAGGAAAAGTCTTTGGGTACATCGCTATAAAAAGCATCCTCAGGTGCCTGATCCGGCAGAGTGTTGCCTGTGTCGCAAAGTATTTTTCGATCGTCAAATGCTGGACAACCATATGCCCACATGTAATCGGAAGCCCATAACCTCCACTGGGgcacatcaacagcaacaaccgcagcagcagcaacaacaacaccaccagCAAGATCAGCTAAGACGCGGTCTGGTGGTATTCAAACACAAAACTGGCgacgatgatgaggatgaagaggatgatgatcaactgcaacaacaagcaCAACATCATATGGATGATACAACTGATGAGGCTGCTGATGCAGTTAATGCTACTGCTGCCGTTGCAGCTTCGTCCTCGTCTACAACTCATGTCAAGATACGCATACCTGAAGTGGCATGCACCATTTGTGGGGCACGATTCATCGATCAGGAAATGTTTACTAAGCACATACAAAAGCATGAACAGGAATTATATGTAGATAATCCATTGGCAGCCATGTTCGATGATGGTCCAGCTGATCCCGGGCAGTTTCAAGTGGAACGACAGAACGAGAATGGGGAATATGCATGTGACTTATGTGCTAAGACATTCCCCCAAGTGATTGCACTTAAAGTGCATCGCAAATGGCATTTCAGAGGTGATAGCAAGCAGAACCCCATCGACAGCGAAGCGACACagttgaacaacaacaacaacaacaattcgaTGTTGCATCTACGCGAATTGCATGCAGTGGGTCTGGTGcccaatcaacaacaacaacaactgaactCCAGCCACAACCAGAACCAGagtcaacaacagcaacaacagagcCACAACTCATCAGCAACctcaacgacaacaacaacgaacaaATCGCTGAAACGGAAACGTGAATTGAAATGCGATTATTGTGCCTCCACCTTcattagcaacaacaatctgCGTCGTCATATGTATGAGCTGCACAAACATGAGGTTAGCCATTTGCCCGAACCACCAGTCATTGTGGTGGATGAGCTACTCTCGTGTCGACGTTGTAATCTCCGATTTGATACAAAGGAATTGTGGATTGAGCATAAATTGGCCGATGCCAAAGTGGTGCGTCCGTTTTGCCCCTTTCAATGGGGATGTGATCTATGTGGCGAATATTTGTCACGCAAAGAGAAACTCATCAATCATATTAATAATCATCTCAAGGAGGATGTTATAGTCCCTGTGGCTGAGAAAGTAACAATAACAGTCTCAGGTGCTGCAACATCGAacacaacaccaacagcaatcGCAACAGAAATATCTAAAACTGGTATATTAAAATCCGAAATAAAACCCGAATCAAATGAGGATAAGTCGTCTTTGGCAGCAAATGCTGATGGAGTCGAACAGAAGGTACCGATAACAGCAGATGGGGCAACGGTAATATCCTTAGAtgtgaaaaaggaaaaggcagCGGCTGCTGATACAGATGATAGCGATCTAGACGaagcagatgatgatgatagttcagatgacgatgatgatggagAGGACACTtctgatgacgatgacgacgatgaggatgatgatgatgacggaGAAGACACTtctgatgacgacgacgatgatgatgatgtgagAGAGGAGCAAGTGGTTGAAATGGAACAGCAACCCAAACCGATTCCAGTTGCTGATGACGCAGATGATCTTGTGGAGGAGGTACTTAGCTCCGaagcagatgatgatgatgacgaagacgacgatgacgatgatgatgatgatgatgatgatgatgaggacgaAGCTGATATCGATGAAGAAGAGATTCCAGCAGAGCCGATGCTTAATGGAATgcatcaattaaaaatgttaccTAATTCAGAGGACGATAATGTTGATGACGATGTcgaagatgaagatgatgggGTAATACCCATTGAAGATATTATTGAGGAGTATGATgtagatgaagatgatgatgttgaaGAGGATGTAGATGgAGAAGTTgtcgatgatgacgatgataatgataacgatgatgatgatgaagaagatgatgatgatgatagaaTCAGAAGAACACCCAGACCAACAGCCTCATCGACTACATCATCATCGGAAAGCGAATcattaacaacaaatacaacaacacaTTCAATGGGTGAGCGGCGTAAAAAgaaggcaacggcaacagcaacagcagcagctacgGCGGCAATTAttgatgctgctgatgctgatgctgatcaGTCTAATAATTCCAGCTATACGTGTGATCTATGTCAACTTTGTTTCGATTCTCAGGAGCAACTGCAGAGCCACATCAAAAGCCATTTTCTGAATGGACCAAAACTGTCAACGACAACAACGGGCCTAAAAATGGTGACAGTAGCGgcagcgacagcagcagcggtgACCACTTCTTCTaataatatcaacaacaataataaaagtaaaatcacaacaacaatgataaaaagaaaatcttcgTCCGTGGAgacaacaaattga
Protein Sequence: MCDTAITVNSTATITSTGATPNASGPQIAATIIAAATGTATKKEPQRTPQNCCRLCIAPATECISIINSYAADKEPLTTKIYNCVNIKITSQDRLSQQICHACISYLNSWQSFKNRCLSSQSKQRQWLETTTTPPTATSKSKLLNYLDLNSAENGTGTGSDNQLAAENEAIVVGSSDMVSDEAADKSTTSASSAAAAATTAALTANILDGIPALKKRKSLTVYVSPKQQQQQHQLQQLQQQQQHHLQLQQQHQQQQLQPAKLTGGWASGGSGGVVGVGGETLIVEVMPPATTIATCSSSSYTSSSQYQSQSQLQRHHQHQQPYRKHQQQRSKRQTQYQYTPRRSRPQGRRAPGHPIPFTTQAPTISINSAAHTATRKLKSKMYLPLDITVPSPPIHVAGTAPHPHPHPPQPPSVTATASSSLGSVLPLPPPKPQSMPYGHMAVATTSTYSTTSTTPTPIPTSTPLLMPPLPAVPIKDEPIDDTDDDYQMKSIDESIDDMVDPTMFLERSELEGDVPLMTSDYDYTAQHGVTAAVAAASLPASAVANVAAAGDSKVASCRACSLQFSTRANARRHERNLHPNLFQLSTDSPNNTPVTKPTPALAAALEIQRAAAAAATAEANRSGGNMSTQKYRQVVMNAFIKCEAGGYDYDNPEQYQPLLSRDKIEFIEQNAEFLEQYQTMTCRCCNKFFSTYKNFMAHVRKKYPLLPRNLCFNCLKMNDSKALFISHLKKRNCINLYRVMNALNNKQNDGIVPVASSPAIVVPATVSAVSVSSTTTTTTSDRPEKLRAKELLVNKLYECKLCPKGFRTKHEFRTHVYDKHADVQRKDNNSIQCSFCGLDFADPVDRRRHYNNMDCIVRLRCMTCDAKLETHQRFLDHVYQDHLGGLSSDNASSTTVSGATVDNSHSPGKKSLLGALGIGSADESRSATAPPPLNTSTPKPVGGGSSSAASTTSASGGLLGGSTSVSRDRDGAPKSQYFSRMPQVCPICGQQYNNYNNVLRHMESKHPNKLPETYKCVRCGLGYPRISYLREHMINVHGVDKNRHSGGFEYIVNADAVKLADGSTPNVYTGRYDYVMKDLMSITNGGTLDDDDEETSGSVAKKIRLDDSSNNSSLMGMAATQQKECPICNAVFSNNIGLSNHMRSHYTASANASASANASGSSASSSTNAALAAANRITPKSLTITAAPPITADGAQTVPHKKESATISSSSSAPQVQAIQFRRSLDQAADRRFRRMRCRICQRRFSSKKSYRYHMLTDHQVQNVQFIKCKLCNAEFAYEKGLKVHLFKVHGKAIKDEMIIKQFECEICSIVYSSELELQQHKRSVHELATASSSAAATTTISSSAVKATTTTSSSSGEITGTTPGIGNNNGASSVPAPLYWYQCKYCPSNFNTNKKLAIHINSHDEFDSNDYSCKDCGNVYSGRKSLWVHRYKKHPQVPDPAECCLCRKVFFDRQMLDNHMPTCNRKPITSTGAHQQQQPQQQQQQHHQQDQLRRGLVVFKHKTGDDDEDEEDDDQLQQQAQHHMDDTTDEAADAVNATAAVAASSSSTTHVKIRIPEVACTICGARFIDQEMFTKHIQKHEQELYVDNPLAAMFDDGPADPGQFQVERQNENGEYACDLCAKTFPQVIALKVHRKWHFRGDSKQNPIDSEATQLNNNNNNNSMLHLRELHAVGLVPNQQQQQLNSSHNQNQSQQQQQQSHNSSATSTTTTTNKSLKRKRELKCDYCASTFISNNNLRRHMYELHKHEVSHLPEPPVIVVDELLSCRRCNLRFDTKELWIEHKLADAKVVRPFCPFQWGCDLCGEYLSRKEKLINHINNHLKEDVIVPVAEKVTITVSGAATSNTTPTAIATEISKTGILKSEIKPESNEDKSSLAANADGVEQKVPITADGATVISLDVKKEKAAAADTDDSDLDEADDDDSSDDDDDGEDTSDDDDDDEDDDDDGEDTSDDDDDDDDVREEQVVEMEQQPKPIPVADDADDLVEEVLSSEADDDDDEDDDDDDDDDDDDDEDEADIDEEEIPAEPMLNGMHQLKMLPNSEDDNVDDDVEDEDDGVIPIEDIIEEYDVDEDDDVEEDVDGEVVDDDDDNDNDDDDEEDDDDDRIRRTPRPTASSTTSSSESESLTTNTTTHSMGERRKKKATATATAAATAAIIDAADADADQSNNSSYTCDLCQLCFDSQEQLQSHIKSHFLNGPKLSTTTTGLKMVTVAAATAAAVTTSSNNINNNNKSKITTTMIKRKSSSVETTN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00556004; iTF_00577948; iTF_00483872;
90% Identity: -
80% Identity: -