Dema013460.1
Basic Information
- Insect
- Drosophila emarginata
- Gene Symbol
- -
- Assembly
- GCA_037075365.1
- Location
- JBAMCD010000221.1:27662085-27665297[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 17 1e-05 0.00091 19.9 0.9 1 23 239 262 239 262 0.96 2 17 2e-05 0.0018 19.0 1.3 1 23 268 290 268 290 0.98 3 17 0.1 8.7 7.4 0.2 2 23 322 343 321 343 0.94 4 17 0.00069 0.06 14.2 0.6 1 23 424 447 424 447 0.95 5 17 0.18 16 6.6 1.2 1 20 454 473 454 475 0.91 6 17 0.039 3.4 8.7 3.8 1 23 484 506 484 506 0.95 7 17 7.8e-06 0.00069 20.3 0.4 1 23 513 536 513 536 0.97 8 17 0.00012 0.011 16.5 1.1 2 23 544 565 543 565 0.96 9 17 0.034 2.9 8.9 0.4 3 21 593 611 591 612 0.93 10 17 0.0064 0.56 11.2 2.0 1 23 670 693 670 693 0.96 11 17 0.0013 0.12 13.3 0.7 1 23 730 753 730 753 0.96 12 17 0.00014 0.013 16.3 1.6 2 23 792 814 791 814 0.95 13 17 0.0048 0.42 11.5 2.5 1 23 828 850 828 850 0.95 14 17 4.8e-05 0.0042 17.8 2.1 1 23 856 878 856 878 0.99 15 17 4.1e-06 0.00036 21.2 0.7 1 23 884 906 884 906 0.98 16 17 0.00012 0.011 16.5 2.2 1 23 912 934 912 934 0.96 17 17 3.6e-05 0.0031 18.2 0.6 1 23 940 964 940 964 0.90
Sequence Information
- Coding Sequence
- ATGAAGCTGCCGATAGTCTGTCGCACTTGCGATGCTAGTGCTATGGACACGGACAAGCTGTATAATCTTGACACGCCCAGCAAGGAATATCCGGAAAAATTGCTGTCTGAGATTCTCGTTGAATTAACGAATATTGATCTGAAGATGAATCTACCCCGAGACCAGAAAATGCCGCAAACCTTGTGCAGTTGTTGCTTAAAAAGGTTAATAGCTTCTTATGACTATGTGAAACAAGCCTTGTCCGCAAACAATTTGCTGATGCGGCAGGTACTGCACGTTACAGATCAAGCAGGATCCGTTAACTCCAACGACTGCTTACAAGAGTCACCAATGGAACTATGTGCCGAGCAACATGTGGAGGTTAAGATGGAAACAGAAGGCGAAGACAGCGACAGGGAAAATGGAGAAAACGGCGACACGGGAAAAATTACATGCACTGAGTTACCCAATTTGGAAGAAGCTGATGCTGTTGGAGATGATGATGGGGAGATCAAGAGACCAATAGATCCGTTGATAATGCTTGATTCGATGgcagttaaaaaagaaagcgaCACACGACCCATCGTAGAAGAGGAGGAGGCTAATGGTGATTGTGAAGATGAAGAATTTGAGCCCGGTGACGATGAGGActCACTTGATAATATTCCACTGCAACAACGAGTTCTGAAGTGGAAGAAGAAACGTGATACCCATAAATTGACAAGACGACGCGCTTTTCAATGCAATGAATGCCCCAAAAGTTTTATACGTGGCGAATCATTAAAGAAGCATAAGTCCAGAGTTCATCAGGCTTCTGGTATTTTTTCTTGCTCGCTTTGCGTAAGAAAATTTAACCGAAAAGAAAATCTGGAGTCCCATCTAAAGGTGCATAGTGAATCCAAGCGCTCATCGCATATCAGCGAGCATAAAAAGGCCAAATCAATTGATGTGAATCTTTGCAAGCCCCATGGCTACAAACTTATAGAGTGCATGATATGTCAGAGtcaatataacaaaatatcgGAATTGCGTCGCCATTTGGAGGACCATCCGCCAATTACCACTCTGGCAAAACGGCCAAACGTAGAATCTTTGGCAGATTTCTTTTATCCGGACTCAAAAAATATAAGCGAAGGGCAACTGAAGCAACTGATATGGCAGGATTTAATGGCTGGCCATTTTCAACGCTTCTATTCAATAACAAACCAATCTGGCTATGAGATTGATCTGGACAGTTCGGAAACCGACAGCGAAGGAGATATGGAACCGGCATCTCAGTTTGATCTGGAATATAACTGTGAGTTGTGTCCGCAAAGATATGCGCGAAAATATCAGCTTTACGACCACCAAAGTCAGGCACATCCCTGGTTGGAGGCTCCACATGTCTGTGGTCGGTGTCAGGCCAGATTTGTTAGTCTCCAACTGTTGCGACACCATAACAAGTCGCAGTGCCGTAATGCCCAAAAGAGGTTTCTTTGCTACAAGTGTCCGTTACGGTTTCGATGGAAGCATAATTTCAGGAGTCATATTCGGGAGCACCGAATTACTAACCAAACTTTTGAGTGTCCTGAATGCAAGCGTGTATTCGACAAGAAGAAGTCACTTACAGTCCATTTGCTTAGCGTGCATGCCGATGAATCAAAGCTGCTTCCCTGCCAGTGGTGCAGCCGCAAGTTCTACCGACGCGACTATCTGGTAAAGCATTTACAGCGTCATGGCTTCAAAGAGCAGGACATACCGCTAGCAGAGACTTTAATAGCTGCCACCTCAAAACCCAATGGTGTTAAACGGATTTGTTGTAAGATTTGTAATTCTCAGTTCGAGCGTATACGTGAGCTTCGTGCCCACATCCAACTGGAGCTGGGTATAAAGCTGTCCATGTCGTCACCTGCATCAGGGCAGGCTAGTGTCGACTCACCCCTTAACTATTCCATCACCAATGAATCTGGTTTCGAGCTGAAAATGGACGATTCGGAAACTGAAGATGAAATGCTATTGCCAGGAGTGACAGGCAATCAACGTGTGGGCTATATGTGTGAGCTGTGTAGTATACAGTGCCGCCGTAAATACGAGATGATCCAACATCAACGTGCAATGCATCGTTTCGATAAGATGCCTTATGAGTGCGACACGTGCATCTTTAAGTGTGTTTCCAAGAACATTATGGAACATCATCGGTTGGGCCAATGCGGTAGCTTGGAGAAAAATTATGCATGCACTCAATGCGGCTACAAATTCATGTGGCCAGAAAATCTCGAACACCATCTCCGTCTACAACATGGGCAGAGTTCTTCCACAGCTAAAGAGCAGCTCATAACTACGAATGATCTCCCGTTGGCAAAGTCTACTACCAAAGAAGAACAATCTCAAGCACAAATCGATGTCCAGCTGCTTCAGTGTCCACATTGTGATCGGACATATCAAATGAAGTCACGTTTAAACAATCACATCCGTGATGTCCATGTGAATGGAGATCGTAAACGGAAGGAAGCCGAAAAGAAATTTCTCTGTTCGCTATGCGGCTGCGCAACAAAGACGGCTGCTTGTCTAGTTACCCATATACGTCGTCATACAGGTGAGAAACCATTTAAATGCGATTTTTGCGAAATGGCATTTCCGAGGCATTCTGAAATGACGGCACACCGACGAACCCACACAGGAGAGAAACCATATAATTGCACAGTTTGTGCGAAAAACTTTGCTCGGTCCGACAAGTTAAAGCGGCATATGCTTATCCATAGTGGTTTAAAACCGCATTCCTGTGCCTATTGCGAAAAGAGTTATCGACAAGCTAAGGAcctaaaattgcatttgcaacaGCATACCGGAGAGTCTCCTTTTATCTGTGGCACGTGTGGAGAGAGGTTTATACAGAGTAGCACACTGGAGAAACACCGCATGATGCGGCGCCATTTCGATGAGGTCGAGGGGGCGTCAATGGCATTAACacgaaactag
- Protein Sequence
- MKLPIVCRTCDASAMDTDKLYNLDTPSKEYPEKLLSEILVELTNIDLKMNLPRDQKMPQTLCSCCLKRLIASYDYVKQALSANNLLMRQVLHVTDQAGSVNSNDCLQESPMELCAEQHVEVKMETEGEDSDRENGENGDTGKITCTELPNLEEADAVGDDDGEIKRPIDPLIMLDSMAVKKESDTRPIVEEEEANGDCEDEEFEPGDDEDSLDNIPLQQRVLKWKKKRDTHKLTRRRAFQCNECPKSFIRGESLKKHKSRVHQASGIFSCSLCVRKFNRKENLESHLKVHSESKRSSHISEHKKAKSIDVNLCKPHGYKLIECMICQSQYNKISELRRHLEDHPPITTLAKRPNVESLADFFYPDSKNISEGQLKQLIWQDLMAGHFQRFYSITNQSGYEIDLDSSETDSEGDMEPASQFDLEYNCELCPQRYARKYQLYDHQSQAHPWLEAPHVCGRCQARFVSLQLLRHHNKSQCRNAQKRFLCYKCPLRFRWKHNFRSHIREHRITNQTFECPECKRVFDKKKSLTVHLLSVHADESKLLPCQWCSRKFYRRDYLVKHLQRHGFKEQDIPLAETLIAATSKPNGVKRICCKICNSQFERIRELRAHIQLELGIKLSMSSPASGQASVDSPLNYSITNESGFELKMDDSETEDEMLLPGVTGNQRVGYMCELCSIQCRRKYEMIQHQRAMHRFDKMPYECDTCIFKCVSKNIMEHHRLGQCGSLEKNYACTQCGYKFMWPENLEHHLRLQHGQSSSTAKEQLITTNDLPLAKSTTKEEQSQAQIDVQLLQCPHCDRTYQMKSRLNNHIRDVHVNGDRKRKEAEKKFLCSLCGCATKTAACLVTHIRRHTGEKPFKCDFCEMAFPRHSEMTAHRRTHTGEKPYNCTVCAKNFARSDKLKRHMLIHSGLKPHSCAYCEKSYRQAKDLKLHLQQHTGESPFICGTCGERFIQSSTLEKHRMMRRHFDEVEGASMALTRN
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00600468;
- 90% Identity
- iTF_00555987; iTF_00600468;
- 80% Identity
- -