Basic Information

Insect: Drosophila dives
Gene Symbol: ftz-f1
Assembly: GCA_035042365.1
Location: JAWNLJ010000133.1:2959435-2970498[+]

Transcription Factor Domain

TF Family: SF-like
Domain: zf-C4|SF-like
PFAM: AnimalTFDB
TF Group: Zinc-Coordinating Group
Description: The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 3 0.19 1.7e+03 -1.9 19.7 48 159 25 148 4 196 0.57

2 3 1.4e-19 1.3e-15 57.8 0.3 1 79 327 404 327 438 0.75

3 3 3.4e-72 3e-68 231.1 1.7 157 408 525 769 491 771 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	3	0.19	1.7e+03	-1.9	19.7	48	159	25	148	4	196	0.57
2	3	1.4e-19	1.3e-15	57.8	0.3	1	79	327	404	327	438	0.75
3	3	3.4e-72	3e-68	231.1	1.7	157	408	525	769	491	771	0.91

Sequence Information

Coding Sequence: ATGTTATTAGAAATGGATCAACAACAGGCGACTGTACAGTTTATATCGTCGCTGAATCTGTCGCCGTTTAGCATGCAACtcgaacaacagcagccagcgaGTCCGGCGCACAGCAACACTAACAACGCTAACAataacagcggcaacaacaacaacaacagcagcagtaatagcaacaacaacaacaacgacaacgataCAAATGCATTAAGCAATTCCGATAACGATTACAGTGCATACACGCTGCAACTGGGCagtcatcagcagcaacagcaacactcaCATCACActcaccaacagcaacaacaacaacaacaacaacaacaacagcaacagcattaccaacagcaacaacaacagaatatTGCCAGCAACAATGCGAATGCAGCGGCGAACCAATTCAATGGTTCCTCCTATtcgtatatatacaatttcgATTCACAGTACATATTTCCGACAGGCTATCAGGAAACGAACTCATCCCATTCACAGCAAAGTGCAAGTGGAGCTGGGAACGCCGCATCAGCTGGCAACTCTGGCCAGCTCCTAAACAACGGAAGCAGCAGCTCGACAGGTAATAGTTATATGCTGTTGCCACCAGGCGCTGGTGGAACCTCAGCATCTGCCGCTGCCCATTTGTCTGGCAATGTGGGTGGCAATCCGGCGACGGGCGTAAGCGGAACTGCAGCCGGAGGTGGTCATCATGGCGGCACCAGCGCCAGTTCTGGCGGTGGCGAAGCCATCGATTTTAAGCATCTGTTCGAGGAGTTGTGTCCCGTCTGCGGAGACAAGGTAAGCGGCTATCACTACGGCCTGCTCACCTGCGAGTCCTGCAAGGGCTTTTTTAAGCGCACCgttcaaaacaaaaaggtCTACACATGCGTGGCGGAGCGGTCCTGCCACATCGACAAGACGCAACGCAAACGTTGTCCATATTGTCGATTCCAAAAGTGCCTGGAGGTGGGCATGAAACTAGAGGCGGTTCGAGCGGACAGGATGCGTGGTGGTCGCAATAAATTTGGACCCATGTACAAACGTGATCGGGCGCGAAAACTCCAAGTGATGCGTCAGCGACAATTAGCGCTGCAGGCGTTGCGCAGTTCGATGGGCACGGACATAAAGCCGACGCCTCTCTCGCCGGGCTATCAGCAAGCATAtccaaatatgaatattaagcAAGAAATTCAAATACCTCAGGTATCCTCACTCACACAATCGCCAGATTCATCACCCAGTCCCATTGCTATTGCCTTGGGTCAGGTGAATGCAAGCGGTAGCGGAGTGATAGCCCCGCCGATCAATGCAGGCAACGGCAATGGTGGCTCTTCacttggcaatggcaacagccacaccaacaacaacaacggcagcagcggTACAGGCAGCGGAAGCGGGGGAGGAGGGGCTGGTGGAGGAGGCTCCAATAGTGGTGGGAACAACATCGTCGCCGATGGCCTGCAACGCAAtggcaatagcaatagcaatagcaacagcagctgccacgATATCGGCACTGGATCTCTGCAAAACTCAGCCGAAGCGAAACTGTGCTTTGATTCAGGCACACATCCATCAAGCACAGCCGACGCGCTTATTGAGCCCCTGAGGGTCTCACCAATGATACGCGAGTTTGTGCAATCGATCGATGATCGGGAATGGCAAACACAACTTTTTGCCCTACTGCAGAAGCAAACGTACAATCAAGTTGAAGTGGATCTCTTTGAGTTAATGTGTAAAGTGCTTGATCAGAATCTATTCTCACAAGTGGATTGGGCAAGAAACACCGTATTCTTTAAGGATTTAAAGGTTGACGATCAGATGAAGCTGCTTCAGCATTCTTGGTCTGATATGCTCGTGCTGGATCATTTGCATCATCGCATTCACAACGGTCTGCCCGATGAGACTCAGCTGAATAACGGTCAGGTCTTCAATTTGATGAGTCTCGGCCTACTGGGTGTGCCACAGCTGGGTGACTATTTCAACGAACTGCAGAATAAACTGCAGGAACTGAAGTTCGACATGGGCGACTATGTTTGCATGAAATTCCTAATACTACTAAATCCAGATGTGCGAGGCATTGTAAACAAGAAGACCGTCTTGGAGGGACATGAGAATGTTCAGGCCGCTCTGCTGGATTACACACTGACATGTTATCCTTCAGTTAATGACAAATTCAGGAGGCTACTGAACATCCTTCCGGAAATTCATGCAATGGCCGCACGGGGAGAGGAACACCTTTACTCAAAACATTGTGCTGGCAGTGCGCCCACACAGACGCTGCTCATGGAGATGTTACATGCAAAGCGGAAAGTGTAA
Protein Sequence: MLLEMDQQQATVQFISSLNLSPFSMQLEQQQPASPAHSNTNNANNNSGNNNNNSSSNSNNNNNDNDTNALSNSDNDYSAYTLQLGSHQQQQQHSHHTHQQQQQQQQQQQQQQHYQQQQQQNIASNNANAAANQFNGSSYSYIYNFDSQYIFPTGYQETNSSHSQQSASGAGNAASAGNSGQLLNNGSSSSTGNSYMLLPPGAGGTSASAAAHLSGNVGGNPATGVSGTAAGGGHHGGTSASSGGGEAIDFKHLFEELCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNKKVYTCVAERSCHIDKTQRKRCPYCRFQKCLEVGMKLEAVRADRMRGGRNKFGPMYKRDRARKLQVMRQRQLALQALRSSMGTDIKPTPLSPGYQQAYPNMNIKQEIQIPQVSSLTQSPDSSPSPIAIALGQVNASGSGVIAPPINAGNGNGGSSLGNGNSHTNNNNGSSGTGSGSGGGGAGGGGSNSGGNNIVADGLQRNGNSNSNSNSSCHDIGTGSLQNSAEAKLCFDSGTHPSSTADALIEPLRVSPMIREFVQSIDDREWQTQLFALLQKQTYNQVEVDLFELMCKVLDQNLFSQVDWARNTVFFKDLKVDDQMKLLQHSWSDMLVLDHLHHRIHNGLPDETQLNNGQVFNLMSLGLLGVPQLGDYFNELQNKLQELKFDMGDYVCMKFLILLNPDVRGIVNKKTVLEGHENVQAALLDYTLTCYPSVNDKFRRLLNILPEIHAMAARGEEHLYSKHCAGSAPTQTLLMEMLHAKRKV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00485910;
90% Identity: iTF_00553087;
80% Identity: iTF_00500360;