Ddif005891.1
Basic Information
- Insect
- Drosophila differens
- Gene Symbol
- -
- Assembly
- GCA_037043665.1
- Location
- JBAMAZ010000233.1:796243-796692[+]
Transcription Factor Domain
- TF Family
- zf-LITAF-like
- Domain
- zf-LITAF-like domain
- PFAM
- PF10601
- TF Group
- Zinc-Coordinating Group
- Description
- Members of this family display a conserved zinc ribbon structure [3] with the motif C-XX-C- separated from the more C-terminal HX-C(P)X-C-X4-G-R motif by a variable region of usually 25-30 (hydrophobic) residues. Although it belongs to one of the zinc finger's fold groups (zinc ribbon), this particular domain was first identified in LPS-induced tumour necrosis alpha factor (LITAF) which is produced in mammalian cells after being challenged with lipopolysaccharide (LPS)[2]. The hydrophobic region probably inserts into the membrane rather than traversing it. Such an insertion brings together the N- and C-terminal C-XX-C motifs to form a compact Zn2+-binding structure [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 2 7.9 8.6e+03 -3.1 0.0 20 27 6 13 2 30 0.52 2 2 1.3e-22 1.4e-19 69.9 9.6 3 68 42 107 40 109 0.96
Sequence Information
- Coding Sequence
- ATGGAGACTGACATCAAGCACACAAACCACCTATCTATGATCACGGCTGCTCCTGCAGCTCCAGTGGCGCCAGTTCCAGTGGTGATGCTTAACATGAATGCTATGCCACCGATGGGCCGTGCGGCGCAGCTCATCAAATGCTCCAATTGCCACAATTTGATGCAGACGCGATTGGAGCGACGAGCGAATAAAAACACGCATCTGCTCGCTCTCCTTCTCTGCCTAACTGGGCTATGGTGCATGGTGCCGCTGCCCTACTGCCTAAAGAGCTGCATCAGTTTGGATCattattgcagctgctgtaATCAGTATCTGGGAAAAGCCGCCAACTAA
- Protein Sequence
- METDIKHTNHLSMITAAPAAPVAPVPVVMLNMNAMPPMGRAAQLIKCSNCHNLMQTRLERRANKNTHLLALLLCLTGLWCMVPLPYCLKSCISLDHYCSCCNQYLGKAAN
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00553434;
- 90% Identity
- iTF_00557570; iTF_00596327; iTF_00542826; iTF_00518830; iTF_00577440;
- 80% Identity
- -