Ddif004088.2


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila differens
Gene Symbol
hang
Assembly
GCA_037043665.1
Location
JBAMAZ010000130.1:276289-292758[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 18 0.38 25 5.6 1.0 3 23 514 535 513 535 0.93
2 18 1.1 71 4.1 3.2 3 22 642 661 640 661 0.89
3 18 0.00082 0.053 14.0 3.3 1 22 772 793 772 795 0.90
4 18 0.094 6.1 7.5 0.1 2 21 807 826 806 827 0.93
5 18 0.00095 0.062 13.8 0.2 2 23 975 997 974 997 0.95
6 18 0.0027 0.18 12.3 0.1 1 23 1005 1028 1005 1028 0.96
7 18 0.00021 0.014 15.8 0.2 2 23 1119 1140 1118 1140 0.97
8 18 0.00039 0.025 15.0 2.9 2 23 1240 1262 1239 1262 0.97
9 18 0.031 2 9.0 0.2 2 23 1271 1293 1270 1293 0.95
10 18 0.00069 0.045 14.2 0.3 1 23 1306 1329 1306 1329 0.97
11 18 0.00017 0.011 16.1 1.1 1 23 1388 1410 1388 1410 0.99
12 18 0.0026 0.17 12.4 0.9 1 23 1418 1441 1418 1441 0.96
13 18 0.093 6 7.5 0.4 2 19 1449 1466 1449 1467 0.94
14 18 0.0021 0.14 12.7 0.3 3 23 1575 1595 1574 1595 0.98
15 18 0.0014 0.093 13.2 0.1 1 23 1630 1652 1630 1652 0.97
16 18 0.00081 0.053 14.0 0.6 2 23 1746 1768 1745 1768 0.93
17 18 0.0087 0.57 10.7 0.3 3 23 1824 1844 1824 1844 0.98
18 18 9.2e-05 0.006 16.9 2.1 1 23 2296 2318 2296 2318 0.99

Sequence Information

Coding Sequence
ATGTGCGACgctgccacaaaaacaacaacaacagcagcagcaacgacaacaacaactgcagcagcagtagcacaaggaacaggaacaggagcTGCTGGCGATACAGCGATGGaagaacaacatcaacgaGAGCGACAAAGCTGCTGTCGCCTATGCATAGCGCCCGCCAGCGAATGCATTTCGATCATTAACAGTTATGCGGCCGATAAGGAGCCGCTGGCCACTAAAATACACAACTGCGTAAATATCAAGATCACATCGGTGGATCGTCTGTCGTTGCATATTTGCCATGCCTGCATCAGTTATTTGAACTCGTGGCAGAGCTTCAAGAATCGCTGCCTCAGCTCACAGTCGAAGCAGCGCCAATGGCTGGAGACGGACAAAACCAAGCAGCAGACGCTACTCGGATACTTGGATTTGAACAGGGCCGAGAATGGCAATACCattgagcaacaacagcagcagcagcagcacgaatTGAAAATGGATTCAGCGACGGCTGCAGCTGAAAAGGTGTCCGCTGCCAACATTTTGGATGGCATACCTCAGCTGAAGAAACGAAAATCGTTAACAGTCTATGTGAGTCCGAGTcataagcaacagcagcaagcacagcaacaacagtcgcaGCAACATTCTCAGCAACAGCATGCAACAGGGGCAAGATCAACAACGAAAACatcagcggcggcggcagcggtggcagAGTCGCAACAAACATTGCAAACCCTTTTATTGCAGGTgcccacagcagcagcagcagcagcgacattgGCAACGTCGtcaacacagcaacagcaacagcagcgcaagtatcaacagcagcagcagcagcagcaacgtggcaagcagcagcaacatcagtatcatcaacagcagcagcgacagagTCGCGTTCGTCAACCGCGACGACAGCATCAAGCCGCAACGGGCAAATTCAGGAGCAAGTTGTATGTGCCATTGGATATATCGGTGCCAGCACTACCAGCGCTgttgccgccaccgccgccagctgttgctgatgcagcgtcgttgccattgccgctgtcgctgccacTTGATTTCAGCCAGAATCcgaatccaaatccaaatcccaatccaaatccaaaataTACAAGTAGCGTTTTAGtgtcgcagccgcagccgccgccgctgccgctgcccccGCCAGTTGCAACAATGAGCAGCAACGAGGCTGCcattgccgctgccactggctgtggtgcaactgcaactgcaactgcaaccgcaGTCACGACTCCATTACTCATGCCGCCGCTGCCTGCCGTGCCCATCAAGGATGAGCCCCTGGACGATACGGATGATGACTTTCAAATGAAGTGCATAGACGAATCCGATGATATGATGGATCCCACAATGTTCCTAGAGCGCTCCGAGCACGAAGGCGATGTGCCACTAAATACCTCCGACTATGATTATACGGCTCAGCATGGCGTGACCGCTGTTGTGGCGGCTGCATCGCTGCCGGCCAGCGCCGTTGCCAATGTGGCCGCCGCTGGCGACTCAAAGGTGGCCAGCTGCCGGGCGTGCAGTCTGCAGTTCTCGACGCGGGCGAATGCGCGTCGCCACGAGCGCAATCTGCATCCGAATCTGTTTCAATTGTCGACAGACTCACCAAATAATACGCCAATCACCAAACCGACACCGGCCCTCGCCGCCGCCTTGGAGATACAGCgtgcagcggcggcggcagcggcaaccGCTGAGGCAACGCGTGCCGCTGCCGGTGGCAATATATCGGCGCAAAAGTATCGACAGGTGGTGATGAACACGTTCATCAAATGCGAAAACGGTGGCTTCGACTACGACAATCCCGAACAGTATCAGCAGCTGTTGTCGCACGACAAGGTCGACTTCATACAGGAGAACAGCGAGTTTCTCGAACAGTACCAGACGATGACGTGTCGCTGTTGCAACAAGTACTTCAACACGTACAAAAACTTTATGGCGCACGTACGCAAAAAGTATCCATTGTTGCCGCGCAACCTGTGCTTCAACTGCCTCAAGATGAACGACTCGAAGGCGCTGTTCATATCGCATCTGAAGAAGCGCAACTGCATCAATTTGTATCGTGTGCTCAACGCACTGCGCACCAAACAGCCAAACTTTGTccatgccaatgccaatgcctcATCCACTTCCACTCCAGCCGCAACGACTGCTgtacaccagcagcagcagcagcagcaacagttggtgACAGCAAacgaaacagcagcaacaacaacagcaacaacatcaacggaTCGTCCGGAGAAGTTGCGTGCCAAGGAGCTCCTGGTTAACAAGCTGTACGAGTGCAAGCTGTGCCCAAAGGGTTTTCGCACAAAGCACGAGTTCCGCACCCATGTCTACGACAAGCATGCGGATGTCCAGCGCAAGGATAACAATTCGATACAGTGCAGCTTCTGTGGCCTGGACTTTGCCGATCCCGTAGATCGGCGAAGGCACTACAATAACATGGATTGCATTGTCCGGCTGCGCTGCATGACCTGCGATGCGAAACTGGAGACGCATCAGCGATTCCTCGACCATGTCTATCAGGATCATTTGGGTGGGGTGAGCAGTGATAATGCATCGTCCACGGCGACGACCAGCGGCATGGATCATTCGCCCGGGAAGCGCAGTTTGCTGGGCGCCCTTGGCATCGGCGTTGTCAGTCAATCATCCAATGATGAGtcgcgcagcagcaacaaccacaacaacaacaataataacaacagcaacaacaacaacaacaataatacacCTCTAACCTCGACACCTAAACTACCAACCgtagcaggagcagcaacagttgttggaggaggaggaggagcagcagcagcaaccagtgGCGGATCGACAACATCGGGCAGTCGAGATGCACCCAAATCACAGTATTTCTCACGAATGCCACAGGTCTGTCCGATCTGTGGCCAGCAgtacaacaactataacaatGTGTTGCGCCACATGGAATCGAAGCATCCCAACAAATTGCCCGAGACATACAAGTGTGTCCGTTGCGGATTGGGCTATCCGCGGATCTCCTATCTGCGGGAGCACATGATCAATGTGCATGGCGTTGACAAGAATCGGCATTCGGGCGGCTTTGAATATATTGTGAATGCCGATGCGGTTAAATTGGCGGATGGCAGCACGCCCAATGTCTATACGGGACGATATGATTATGTGATGAAGGATCTGATGTCTATAACAAATGGTGGGACACTCgatgatgatgacgatgatggcGGCAACGGCGGCAACATTGCCAAAAAGATGAGACTCGAtgatagcagcaacaacagcagcagcatcaacatgAGCAGCATTGCCAACCAGCAGAAGGAGTGCCTCATCTGCAATGCGGTGTTTAGCAACAATATTGGTCTATCGAATCATATGCGTTCCCATTACACAGCATCGATAACGACAAGTGCTGCTCTGGCGGCTGCCAATCGCATGACGCCCAAATCGCTGACAATAACAGCGACGCCACCGCTGGAGacaacgacagcaacaacaactgcatctGGAgttgcagcagtggcagcatcatcatcaggagCAGTCgcctcaacagcaacagcatcaggaTCAGGCTCATCATCCGGCAACTTGCCGCCAGCAATGGTCCATCAGACGGCACAGGAGCAGGCGGTATTCCGTCGCAGTCTGGATCAGGCGGCCGATCGACGCTTCCGTCGAATGCGCTGTCGCATCTGTCAGCGCAGATTCAGTTCGAAGAAATCGTATCGCTACCACATGCTCACCGACCACCAGGTGCAGAATGTGCAGTTCATCAAGTGCAAGCTGTGCAATGCGGAGTTCGCCTACGAGAAGGGGCTAAAGGTGCATCTGTTCAAGGTGCACGGCCGGGCCATCAAGGACGAGATGATTATCAAGCAGTTCGAGTGCGATGTCTGCTCCACGGTCTACAGTTCCGAGATGGaattgcagcagcacaagcgCAGCGTACACAAGTCACACGCCAGTgattcatcatcatcagcagctggtggtgctggtgctgctgctggcaaatcATCATTGAAATCTGCTACTGCTACTATCTCATCGACGGCTGAGCTGGTCGCAGACACATCATCCTCGTCGGGCACGGCGGGTGCGGCAATTCTGCTGCCACTCTACTGGTACCAGTGCAAATATTGTCCATCCAATTTCAACACCAACAAGAAACTGGCCATCCACATCAACTCGCACGACGAGTTCGACTCGAATGATTACTCGTGCAAGGACTGCGGCAATGTCTACAGCGGCCGCAAGAGCCTCTGGGTGCATCGCTACAAGAAGCATCCGCAGGTGCCGGATCCCGCCGAGTGCACGCTCTGCCGCAAGATGTTCTTCGATCGCCAGATGCTGGAGAATCATACGCCCACCTGCAATCGCAAGCCAATCACTGCCACCGGCGCCCATCAGcaggatcaacagcagcagcagcagcaacaacaacagcagcaacaacagctgcagctgcaacatcaTCAGCGACGCATCTTCAAGCACAAAAcgggcgatgatgatgacgaggaggaggacgatgaTCAGTTGCTGCTAATGGACGAtggcggtggcggcagcaATGATAGCAATGCTGGCAATGCCAttgcgtcagcagcagcagcagcagcggcagcagcagcagcagtcacaatAAATACGAGCACAATGAAGATACGCATTCCGGAGGTTGCATGCACCATTTGCGGTGCCCGTTTCACCGATCAGGAAATATTCACCAAGCATATACAGAAACACGAACAGGAACTGTATGTGGACAATCCGTTGGCGGCGATGTTCGATGATGGGCCAGCGGATGCCGGACAATTTCAGGTTGAGCACCAAAACGAGAATGGGGAATACGCGTGCGATTTGTGCACCAAGACGTTCCCGCAGGTGATAGCGCTCAAGGTGCATCGCAAGTGGCATTTCAGAGGTGATAGCAAGCAGATCCCAATCAACGACGGCGAAGCGACAACGctgaacaacagcagcaacaacagcagcagcagcaacaacaacaacaacaacaacaacaattcgctGAGCTCATCATCGATGCTGCATCTACGCGAACTGCATGCGGTGGGTCTGATGcccaatcagcagcaacaccaaaaacaacaacagcaacaacaacagcagcagcaacagcagcagcagcagcaacaacggacGAGCAAATCAATGAAACGGAAACGTGAACTGAAATGCGAATATTGCGCCTCCACATtcattagcaacaacaacctgcGACGCCACATGTACGAGCTGCACAAGCACGAGGTCAGCAACCTGCCAGAGCCGCCCGTGATTGAGGTGGATGAGCCGTTGGCGTGTCGCCGTTGCGGCGATCTACAATTTGATACCAAAGAGCAGTGGATCGAACATAAGCTGGCCGATGCGCGAGTGGTGCGTCCATTCTGTCCATTCCAATGGGGCTGTGATCTGTGCGGCGAGTATTTGTCGCGCAAGGAGAAGCTCATCAATCACATTAACAATCATCTCAAGGAGGATGTGATTGTGCCGGTCGCCACCAAGCCACCAGCACCGGCAGCAGCCCATAAaactgcagcggcagcagcagcagcaacaacaacaacagcggcaacaacaacaacaattgccgccgcagcaacagttgcagctgctacatcagcagcagcagcaacggcggcgACGAAGTcagcgtcaacagcagcaaaagaacaTAAGGctaaacaacagcagcaggaggatgAGGACCTGCAGCTGGATGATGAGAAGCTagcgaagcagcagcaacaggaggaggaggaggatgataGTGATATGGATGATGGTAGCGATAGTGGcaatgatgatgaggagggCAGCACCAGtgctgacgatgatgatgatgatgacgatgatgatgaggagggcgacggcgatgacgacgacgatgatgatgacgaagaagaagacaacgacaatggcgaaaatgttgttgcacagcagcaaatgctgcaacaacagcctcaaaatacaaacagcaacaccaacaacaacaacagcagcgcaatTGAAAATGACGATGATCTCATTGAGGAGGTGATCGAGGATGATGGCATTGTCGAGCAGCTGGacgtcgatgatgatgaggaagacgatgatgatgatgacgacgatgatgatgatgatggcgaagacgatgacgatatcgatgaggatgaggacgaggacgatgagCAACATCAGCCGAGGCGCCTCAATTTCGACTACTCGCGCACCGACAGCGCCAAGCTAAATGGCAACGGTGGCAAACAGTCTGTGGCAAAATCAAAGACACAGCCACAGTTGCAgccacagttgcagcaacagttgcagacACAGCCAATGCTGGTCATGCACAGTAGTAGTAGTCGCCACGTGGATGATGGCGAGGAGGAGGTGGATGATAtggatgatgatgttgatgacgatgatgttgTGGGTGAAGCGATGACCATTGATGATATTATTGAAGAGGATGATGGTGTGGATGATGACGATGTGGTTGGTGTcggtggtggtgttgttgaggatgatgatgatgatgacgaagaagatgatgatgacgacgatgatgatgacgatgatgttgAGGAGGAcatggatgatgatgatgatgatgatggggaCGACGACGATGCCGATGTCAACAACACCAATATTGGCAACGGTGTTGGCCGTGTGGGTCGAGAAGatgctgatggtgatggtgatggggatggtgatggtgatggtgatgttGATGGTGGTTCATCATCATCTGAGAGCgagtcgacaacaacaacatcgcaTTCAACTGttgCATCAGCGGCACATGGCGCTGCCGCTGATCAGTCTAATTCCAGCTATACGTGTGATCTATGTCAACTTTGTTTCGATTCCCAGGAGCTACTGCAGACACATATTAAAAGTCATTTTCTCAATGGGCCATCGGcggggagcagcagcaacagcaacaagagcaacggCGCCAGCAGGagcaccaataacaacagcaacaacaacagtagcaacagcaacagcagtaacaaaatCAATACCAAAAAGTCCGGCTTGGATGCAacgaagacaacaacaacaacaacaacagttaagGCTGCTGCAGTAGCGGACGCTGTAACGGGCTTCAACTGA
Protein Sequence
MCDAATKTTTTAAATTTTTAAAVAQGTGTGAAGDTAMEEQHQRERQSCCRLCIAPASECISIINSYAADKEPLATKIHNCVNIKITSVDRLSLHICHACISYLNSWQSFKNRCLSSQSKQRQWLETDKTKQQTLLGYLDLNRAENGNTIEQQQQQQQHELKMDSATAAAEKVSAANILDGIPQLKKRKSLTVYVSPSHKQQQQAQQQQSQQHSQQQHATGARSTTKTSAAAAAVAESQQTLQTLLLQVPTAAAAAATLATSSTQQQQQQRKYQQQQQQQQRGKQQQHQYHQQQQRQSRVRQPRRQHQAATGKFRSKLYVPLDISVPALPALLPPPPPAVADAASLPLPLSLPLDFSQNPNPNPNPNPNPKYTSSVLVSQPQPPPLPLPPPVATMSSNEAAIAAATGCGATATATATAVTTPLLMPPLPAVPIKDEPLDDTDDDFQMKCIDESDDMMDPTMFLERSEHEGDVPLNTSDYDYTAQHGVTAVVAAASLPASAVANVAAAGDSKVASCRACSLQFSTRANARRHERNLHPNLFQLSTDSPNNTPITKPTPALAAALEIQRAAAAAAATAEATRAAAGGNISAQKYRQVVMNTFIKCENGGFDYDNPEQYQQLLSHDKVDFIQENSEFLEQYQTMTCRCCNKYFNTYKNFMAHVRKKYPLLPRNLCFNCLKMNDSKALFISHLKKRNCINLYRVLNALRTKQPNFVHANANASSTSTPAATTAVHQQQQQQQQLVTANETAATTTATTSTDRPEKLRAKELLVNKLYECKLCPKGFRTKHEFRTHVYDKHADVQRKDNNSIQCSFCGLDFADPVDRRRHYNNMDCIVRLRCMTCDAKLETHQRFLDHVYQDHLGGVSSDNASSTATTSGMDHSPGKRSLLGALGIGVVSQSSNDESRSSNNHNNNNNNNSNNNNNNNTPLTSTPKLPTVAGAATVVGGGGGAAAATSGGSTTSGSRDAPKSQYFSRMPQVCPICGQQYNNYNNVLRHMESKHPNKLPETYKCVRCGLGYPRISYLREHMINVHGVDKNRHSGGFEYIVNADAVKLADGSTPNVYTGRYDYVMKDLMSITNGGTLDDDDDDGGNGGNIAKKMRLDDSSNNSSSINMSSIANQQKECLICNAVFSNNIGLSNHMRSHYTASITTSAALAAANRMTPKSLTITATPPLETTTATTTASGVAAVAASSSGAVASTATASGSGSSSGNLPPAMVHQTAQEQAVFRRSLDQAADRRFRRMRCRICQRRFSSKKSYRYHMLTDHQVQNVQFIKCKLCNAEFAYEKGLKVHLFKVHGRAIKDEMIIKQFECDVCSTVYSSEMELQQHKRSVHKSHASDSSSSAAGGAGAAAGKSSLKSATATISSTAELVADTSSSSGTAGAAILLPLYWYQCKYCPSNFNTNKKLAIHINSHDEFDSNDYSCKDCGNVYSGRKSLWVHRYKKHPQVPDPAECTLCRKMFFDRQMLENHTPTCNRKPITATGAHQQDQQQQQQQQQQQQQQLQLQHHQRRIFKHKTGDDDDEEEDDDQLLLMDDGGGGSNDSNAGNAIASAAAAAAAAAAAVTINTSTMKIRIPEVACTICGARFTDQEIFTKHIQKHEQELYVDNPLAAMFDDGPADAGQFQVEHQNENGEYACDLCTKTFPQVIALKVHRKWHFRGDSKQIPINDGEATTLNNSSNNSSSSNNNNNNNNNSLSSSSMLHLRELHAVGLMPNQQQHQKQQQQQQQQQQQQQQQQQRTSKSMKRKRELKCEYCASTFISNNNLRRHMYELHKHEVSNLPEPPVIEVDEPLACRRCGDLQFDTKEQWIEHKLADARVVRPFCPFQWGCDLCGEYLSRKEKLINHINNHLKEDVIVPVATKPPAPAAAHKTAAAAAAATTTTAATTTTIAAAATVAAATSAAAATAATKSASTAAKEHKAKQQQQEDEDLQLDDEKLAKQQQQEEEEDDSDMDDGSDSGNDDEEGSTSADDDDDDDDDDEEGDGDDDDDDDDEEEDNDNGENVVAQQQMLQQQPQNTNSNTNNNNSSAIENDDDLIEEVIEDDGIVEQLDVDDDEEDDDDDDDDDDDDGEDDDDIDEDEDEDDEQHQPRRLNFDYSRTDSAKLNGNGGKQSVAKSKTQPQLQPQLQQQLQTQPMLVMHSSSSRHVDDGEEEVDDMDDDVDDDDVVGEAMTIDDIIEEDDGVDDDDVVGVGGGVVEDDDDDDEEDDDDDDDDDDDVEEDMDDDDDDDGDDDDADVNNTNIGNGVGRVGREDADGDGDGDGDGDGDVDGGSSSSESESTTTTSHSTVASAAHGAAADQSNSSYTCDLCQLCFDSQELLQTHIKSHFLNGPSAGSSSNSNKSNGASRSTNNNSNNNSSNSNSSNKINTKKSGLDATKTTTTTTTVKAAAVADAVTGFN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00596083;
90% Identity
iTF_00486003;
80% Identity
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