Ddem006275.1
Basic Information
- Insect
- Drosophila demipolita
- Gene Symbol
- Aef1
- Assembly
- GCA_035042405.1
- Location
- JAWNLI010000066.1:1683009-1684112[+]
Transcription Factor Domain
- TF Family
- zf-GAGA
- Domain
- zf-GAGA domain
- PFAM
- PF09237
- TF Group
- Zinc-Coordinating Group
- Description
- Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 4 0.0048 27 4.9 0.1 21 48 219 246 214 250 0.85 2 4 2.8e-05 0.16 12.1 0.0 21 52 247 278 244 279 0.89 3 4 0.062 3.5e+02 1.3 0.1 21 46 275 300 273 303 0.88 4 4 8.6e-05 0.49 10.5 0.1 21 47 303 329 299 336 0.88
Sequence Information
- Coding Sequence
- ATGATGCATATCAAGAGTCTGCCGCACGCACATCAGGCCGCCGCGGCAATGAGCAATTGTGACATTGTGATCGTCGCCGCGCAGCCGCAAACAACtagcgccaacaacaacaatgatacTGTTACACAGGCGAGCCATGCAAGCcatgtggcagctgtggcCCATGCACAactccagcaacaacaacaacaacagcatcagcaacaacaacaacaacagcagcaacaacagcagcaacaacagcagcaacaacaacagcagcagcaacaacagcaacagcaacaacaacagcagcaacacaatcaacagcaacaacaacaacagccgcccGCGCCGACAGAAATCGCCTTACCctttaatatgcatttgaGCGGAATTTCAGCGGAGGCACACAGTGCCGCACAGGCGGCCGCAATGGCAGCTGCGCAGGCCGCGGCAGCGCAAGCCGCCGCCGCGGATCAACAGCAGCCGGCGGCAGCGCCTCAATCGGCATCATCATCGCATACGCTTGCACATTTGGTTGCTAACGCTACACATAGTCCTACAACGCTTGCGGGTGAATCGCACTACGTCAGCAATGGGCATTCGGGCAATGAGCATTCAGGCGAGGGCAACGGTTCGAGCGGTGGTAGCGGCGGGGGTGGCGGTCGCGACCAGGAGAAGCCGTTCCATTGCACTGTGTGCGACAGACGATTTCGTCAGCTGAGCACACTGACCAATCATGTGAAGATCCATACCGGCGAGAAGCCTTACAAATGCAACGTTTGTGATAAGACGTTCCGTCAATCGTCAACGCTGACGAATCATTTGAAAATTCATACTGGCGAAAAGCCTTACAATTGCAACTACTGTCCCAAGCATTTTCGTCAGTTGAGCACATTGGCCAATCATGTCAAGATTCATACGGGTGAAAAGCCGTTCGAATGCGTGATATGCAAGAAACAATTCCGGCAATCGAGCACGCTCAACAATCACATAAAGATCCATGTCATGGACAAGGTCTACGTTCCTGTCAAGATCAAAACGGAGGAGGACGAGGGGTGA
- Protein Sequence
- MMHIKSLPHAHQAAAAMSNCDIVIVAAQPQTTSANNNNDTVTQASHASHVAAVAHAQLQQQQQQQHQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHNQQQQQQQPPAPTEIALPFNMHLSGISAEAHSAAQAAAMAAAQAAAAQAAAADQQQPAAAPQSASSSHTLAHLVANATHSPTTLAGESHYVSNGHSGNEHSGEGNGSSGGSGGGGGRDQEKPFHCTVCDRRFRQLSTLTNHVKIHTGEKPYKCNVCDKTFRQSSTLTNHLKIHTGEKPYNCNYCPKHFRQLSTLANHVKIHTGEKPFECVICKKQFRQSSTLNNHIKIHVMDKVYVPVKIKTEEDEG
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00518660;
- 90% Identity
- iTF_00496852;
- 80% Identity
- iTF_00499094;