Basic Information

Insect: Drosophila demipolita
Gene Symbol: RREB1
Assembly: GCA_035042405.1
Location: JAWNLI010000490.1:739259-745886[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 13 0.034 2.4 8.7 0.8 1 21 273 293 273 295 0.93

2 13 0.00032 0.023 15.1 0.2 1 23 305 327 305 327 0.98

3 13 0.00024 0.017 15.5 7.2 1 23 333 355 333 355 0.98

4 13 0.52 37 5.0 2.4 2 20 588 606 588 608 0.93

5 13 0.016 1.1 9.8 0.2 1 23 753 775 753 775 0.97

6 13 1.2e-05 0.00083 19.6 0.7 1 23 785 807 785 807 0.99

7 13 0.0008 0.056 13.9 2.0 1 23 813 836 813 836 0.97

8 13 0.0029 0.2 12.1 2.0 1 23 1118 1141 1118 1141 0.95

9 13 8.3e-05 0.0058 17.0 0.3 2 23 1538 1559 1537 1559 0.97

10 13 0.14 9.8 6.8 6.3 1 23 1565 1588 1565 1588 0.97

11 13 9 6.3e+02 1.1 3.4 1 23 1704 1727 1704 1727 0.78

12 13 0.0081 0.57 10.7 0.5 3 23 1785 1805 1783 1805 0.96

13 13 0.0013 0.09 13.2 4.8 1 23 1811 1833 1811 1833 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	13	0.034	2.4	8.7	0.8	1	21	273	293	273	295	0.93
2	13	0.00032	0.023	15.1	0.2	1	23	305	327	305	327	0.98
3	13	0.00024	0.017	15.5	7.2	1	23	333	355	333	355	0.98
4	13	0.52	37	5.0	2.4	2	20	588	606	588	608	0.93
5	13	0.016	1.1	9.8	0.2	1	23	753	775	753	775	0.97
6	13	1.2e-05	0.00083	19.6	0.7	1	23	785	807	785	807	0.99
7	13	0.0008	0.056	13.9	2.0	1	23	813	836	813	836	0.97
8	13	0.0029	0.2	12.1	2.0	1	23	1118	1141	1118	1141	0.95
9	13	8.3e-05	0.0058	17.0	0.3	2	23	1538	1559	1537	1559	0.97
10	13	0.14	9.8	6.8	6.3	1	23	1565	1588	1565	1588	0.97
11	13	9	6.3e+02	1.1	3.4	1	23	1704	1727	1704	1727	0.78
12	13	0.0081	0.57	10.7	0.5	3	23	1785	1805	1783	1805	0.96
13	13	0.0013	0.09	13.2	4.8	1	23	1811	1833	1811	1833	0.99

Sequence Information

Coding Sequence: ATGCTcgccacacagcagcagcagcaacagcagcagcagcaacaacagcaacaatcgcacacagcagcagcagcagcagcaacacttgaGGATGCTCGCGATTTGGGCTTAATGGAGACGCGACAACGTCGCGATTCGAGTACATCTGAATCCTCGCTGGAGCATTTGGATTTGGGTCGCACGCCAAAAaagttgagcagcagcagcggcgcacCGCAGCCAACGTCGACGCCGCACGACACAGCAGTGACAGCGACGTCGCGCAAGCGGAAACTGCGACAgcaaaaccagcagcagcagcaacagttgccgctCTCCGATGAggatcagcatcagcatcagcagcagcaacagcagcagctgttcgACTCTTCAGCGCAGCGATTGCGTCACAAGCAGCGACGCAGCGCTGTTCCTGCCGCCACCAGTGCCAGCATCGTTGTTGACTACAGCGCCAGCGGAGACGCCAGCTCGCTGCGCAAAAAGTTCCGACTGAAtcgcagcagcgccagcagcaatgCTGCCAACGGTGATTTATCCGAGTCTGGCTTCGTTGATGGCAGCGCCCTCAGTGGCTATCTgcttggcaacaacaacaacaataataacaacaacaacaacaacaataacaataacaacaataacaacaacaatattagtagtagtagcagcagcagcgcagtcgCTCAGTCAGCAGCATCAGTCGCAGCGTCGGCAGCGCAGCATGCGTCAAGCGTTAGCAGCTCGGGCGGTTCCTCGCCGCAGGGCCTTTCGAGCGCCGAGTCGGGCATCGGCGCCGGCGATGAGCACATGAAATATCTGTGCCCCATCTGTGAGGTCGTCTCGGCCACGCCCCACGAATTCACCAATCACATTCGCTGCCACAACTACGCCAACGGCGACACCGAGAACTTCACCTGCCGCATCTGCTCCAAGGTGCTGTCGTCGGCATCCTCGCTGGACCGGCATGTGCTGGTGCACACTGGAGAGCGTCCGTTCAACTGTCGCTATTGCCACTTGAACTTCACAACCAATGGGAACATGCATCGACATATGCGCACCCACAAGCAACATCAGgcatcgcagcagcagcagcagcagcaacagcagcaacagcagcagcaacagcagcagcagcaggcacagtcgcagtcgcaacagcagcaacagcgacgccAGCAACATGCGGGTGGAGTTGGAGCCGCTGGCTCCGGATCGGGATCGGCACAGTTGTTAACAACGCGAGCCGAGAGCTATGAGAGTGATGCTAGCTGCTCGACGGATGTGTCCAGTGAGCTGAACagtcacagcagcaacagcaatcaatccaaccacaacaacaatagccacaaaacgaacaacaataacaacaataaaaacaacaacaacaacaacaacaacaatgaggaTGAGGtcgagctggagctggaggatGAGCAGCTAGTGTTGAGCAGCAAACAGCGACGCCTCAAGGCAGTCGtcctaaacaacaacaatattattagGGATGAGCAGCACGAGAATCGGGCGGATGATGATTCGGATGTGGACAGCGTTGATAGTGTTGCCCAGGTGATAACGAGCACACCAGATGTGGCCACGTTGCTCGCCTCGGGCGGCACCTCGCCGAGCCACTCGCATTCGGAATCACATTCACCgcccctgctgctgcagagCTGCCCCGCCTGCAATTCGGGTGAATTTGAATCTGTGCCAGCGTTGTGCGCCCATCTGGATGCCGAGCATGCGGACATACCGGCCAAGTGTCGCGAGTGCGAGGTGATCTTTGCCACACATCGACAGCTGCAGTCGCATAGCTGTCGTGGATTGCCGCCGCTCCTTGGTGTCAGCTCATCGCCACTGCACAAGCAAGAGGAGCACGaactggaggaggaggagcagcagcagcacgaggAGGACCATGAACCGCAGCACAAGCAGGAGGAACAGGAGCAGGCTGAGCAGCGCGAATGTGAAGATTTCTTCCAGCAGCTGTATCTGAAGAATAAATCTTCAGCAGCGCTCCTTCCCTCTCCGATCAAACATGAGCCGGCGGATCAGCGACAGGATCTGGCCGACATTCAAAGCATACTCAATATGACCAGTTCCAGCTGCACCTCGAGTTTCCTGCGCAATTTTGAGCAGTCGGTGAACACGCCCTGCTCCAGCCAATATAGCGTCGATGGACGCGATGGCGAGGAGGAGGCCCAGGATGCCTTCACCAATGAGTTTCGCAGAATGAAGCTGCGCGGTGAGTTCCCCTGTAAGCTATGCAGTGCCGTCTTTCCCAATCTTCGGGCGCTCAAGGGCCACAATCGCTACCATCTGTCGGAGGTGGGCGCCGCTGGCCCATTCCGTTGCAACATGTGCCCCTATGCCGTCTGCGACAAGGCGGCGCTCGTTCGGCACATGCGCACCCACAACGGGGATCGGCCCTACGAGTGCGCCGTCTGCAACTATGCCTTCACCACCAAGGCGAACTGTGAGCGCCATTTGCGCAATCGACATGGAAAGACCAGTCGGGATGATGTGAAACGTGCGATTGTTTACCATCCAGCCGAGGATGCCAGCTGCGAGGAAAACAAATCCCGCACCGATGCCGATATCCTAACCGAGCTTAGCGGCTATCGCTGTCCCACACCCACAGAGCACAGTTCCTCGGCTAGCTCCTCGTCACAGCTAAAGCACATGTTGCTGGCGGAGCCGACACCAGCCGTAAaggtaacagcaacaacagcagcagcagcagcagcggcggcaaccACATCGATGCAGCAACAACCGCTCAAGATTCAGGTGAAGAGCTTGGATCAGCTGGTGGATAAGCCACTGCCTGCACTCGATCTCAGCATGGATGCGCTCGACTTGAGCAAGAAGCCCGCACAGCTGCTGGCCGAGCAGAGGGAGCAAAGGGAGCAGCTCGAAAGACACgaattgctgttgcagcagcagcagcaccagcaacaacaacagcagcagcaacagcagcaacaacaacagcagcagcagcagcaacaattgtttgGGGCTGGCGATGCAGCTGCTCAGTATATGCAACAGCTGTTGCGCAGCTTCATGCTCCAGCAGTCACCCGGTTTTCCTTTCTTTGGTTTTAtggcgccaccgccaccaacagcggcagcagcagcagacaagtcaatgccaacaaatccaacagcagcagcagctgcagcagcagcagcagcagcaagcgcaacagcagcaacaattgctgcattGCCATTGTCGCTGCCCGTGCCACTGCCCGCTGGTGGTCCCGTCAAGATGGTCATCAAGAATGGCGTCCTGATGCCCAAGCAGAAACAGCGCCGCTATCGCACCGAGCGTCCCTTTGCCTGCGAGCATTGCTCGGCCCGCTTCACGCTGCGCTCCAACATGGAGCGGCACgtgaagcagcagcatccacagTTCTATGCGCATCGCCAGCGACACCGCAGCGGTCATCATGTGATGCGTGACCGGGCTGCATCCTCCAGTGCTGTCCAAGCGGCAGCCGCTGctcaggcagcagcagcagcagcagctgccgcagcaatGAGTAATctcagccagcagcaacagttgcagcagcagcaacagcaacagttgcagcattcACATCACGTCCATGCGCCAATTTCGGAGCAGGTCAAATATGCCATTTTGGCGCAGCAATTGAAGGCGCGCAAGGATACGGATTTGTTGCAACAGGCACTGGCACATGGCTCTAGCAGTGTGGTCACCAATCCGCTGCTGCATTTCACctacaacaagcagcagcagaagcaacagttGAGCAACAACACTGGCAACTCTTTGGTGCTGGACGATGATGAGCCGCCCAAGCTGATTATTGACGAGGATGATGAGGATGTGGACGGCGAGGGCGAGGGCGAGGGcgaggacgatgatgatgaggaggaggagggggaTCATGAATTTAATGTCGATgacgaggagcaggaggaTGAAGAGATGGACTTGGACGATGAACATCAGCAGCATGAGCTGCCGCACAAGgaggatgatgacgatgatgatgatgatgatgatgatgataacgatgatgcaacagccgcagcagcagcagcagcagaggcgtcgctgcaacaattgcaggCAACAAATGATAAACTGCAATCGAAGCCAATTGAGGCGGCCAAAAAGGCAGCGGAGATCATAATGGAGCAGGCAATCAAGGAGGGCGAGCAGTTGGCCTCCGAGAAGCAGCCGCGTTCTCAATCCCAGTCCAGAGGCGGCAATAAGCCAGCgacgccaacaacaatgaaaacaatgaTTGCACAAGCGGAATCGGTGGCCAAGTCCTTGAAGGAGGTGGCCAGTTCACCGTTCAAGGATGAATCTCAGGATCTGGTGCCTGTGGCCAAACTGGTGGACAATGCGACCAGCAATCAGGTGTCATTCAATAGCTATTTCCGTCCCAGCGACGTGGCCAATCACATGGAGCAGAGCGACGAGGAGGGTCTCGTCGCCAGCGGCAGCGCCAGCGAGAGCAACAATTCCGGCACCGAGGAtgtgaccagcagcagcagcagctgcggcaacGACACCAAAAAGAAATCCGCCTACAGCCTGGCACCGAATCGTGTCAGCTGCCCGTATTGCCAGCGCATGTTCCCCTGGAGCAGCTCGCTGCGCCGCCACATCCTGACGCACACCGGCCAGAAGCCGTTCAAGTGCTCCCATTGCCCGCTGCTGTTCACCACGAAGAGCAACTGCGATCGCCATCTGCTGCGCAAGCATGGCAACGTTGAGTCCGCCATGTCTGTCTATGTGCCCACCGAGGATGTCAGCGAGCCGATACCCGTGCCCAAGTCCGTCGAGGAGATTGAGCTCGAGGAGCAGCGACGTCGCCAGGCGGCCGAGGCCGAACGGGAGCAGATCGAGCGCCAAAAGGAGCGCGAACGTGAACTGGAATTGGAACGGGAAAGGGAGCgggaacagcagcaattgaTCCAACAGTTGCGCCAACAAatggccgctgctgcagcagctgttgctgttgccgttgtcacTGCACCAGCGCATCCAGCAGCACCACAGCCAGCCCAATCGCCACCGGGCCTGGAGGCGAGCAGTGATCTGCCCTACAAATGCCATCTGTGCGAATTCTCGTTTGGCGAGCGGCTGCAGTGTCTCGAGCACATCAAGCAGCTCCACTCGCACGAATTCGCGCTGCTCCTGGCCAAGGGGGCCATCGAGACGGATGGACaactgcagcatcagcagttgCCAGTGGCGGCTGGTGGTGCCTCGCATTCGGATGATGAGGCTGCCGCTGTCGGCACCAGATCGGGCAAATATCCCGACTATAGCAATCGGAAAGTGATTTGCGCATTTTGCGTGCGTCGCTTCTGGTCGACGGAGGATCTGCGGCGACATATGCGCACCCATTCCGGCGAGCGTCCTTTCCAGTGCGAGATCTGCTTGAGGAAGTTCACATTGAAGCACAGCATGCTGCGGCACATGAAGAAGCATAGTGGACGCAGTCACAATGCTGGCGAACTCGATCATCAATCCGATTGTTCCGATGATGAGCAGATGTTGCCCTGCTCCCCACCCTCAACGCCAACGcccactaacaacaacaacaacaacaacaacacttgccagaacaacaacaacaacaacaacaacagcagcaacaacaacaacaacaatagcaacagcaagcaGGTGCTGCGCGAGCTGCTGGGCAAGGCAAACGAGTGGCGAGTGAGTCGCCTGGGTGAGCATAAGGAGAACATTGccgaggcaacaacaacaccgtcagcagcaacagcagcagcggcagcaacagctgcagcagcagcagcagcggcagcaacagctgtgGCCAGTGGCGATCTAATTGGTAATCTGTTGGGGATTAGTGATCAGGGCATACTAAACAAGCTGCTCTCCTCACCAGACGAAGCTGCCAAGCTGCTGGGAGTGGAGAAGTAA
Protein Sequence: MLATQQQQQQQQQQQQQQSHTAAAAAATLEDARDLGLMETRQRRDSSTSESSLEHLDLGRTPKKLSSSSGAPQPTSTPHDTAVTATSRKRKLRQQNQQQQQQLPLSDEDQHQHQQQQQQQLFDSSAQRLRHKQRRSAVPAATSASIVVDYSASGDASSLRKKFRLNRSSASSNAANGDLSESGFVDGSALSGYLLGNNNNNNNNNNNNNNNNNNNNNNISSSSSSSAVAQSAASVAASAAQHASSVSSSGGSSPQGLSSAESGIGAGDEHMKYLCPICEVVSATPHEFTNHIRCHNYANGDTENFTCRICSKVLSSASSLDRHVLVHTGERPFNCRYCHLNFTTNGNMHRHMRTHKQHQASQQQQQQQQQQQQQQQQQQQAQSQSQQQQQRRQQHAGGVGAAGSGSGSAQLLTTRAESYESDASCSTDVSSELNSHSSNSNQSNHNNNSHKTNNNNNNKNNNNNNNNNEDEVELELEDEQLVLSSKQRRLKAVVLNNNNIIRDEQHENRADDDSDVDSVDSVAQVITSTPDVATLLASGGTSPSHSHSESHSPPLLLQSCPACNSGEFESVPALCAHLDAEHADIPAKCRECEVIFATHRQLQSHSCRGLPPLLGVSSSPLHKQEEHELEEEEQQQHEEDHEPQHKQEEQEQAEQRECEDFFQQLYLKNKSSAALLPSPIKHEPADQRQDLADIQSILNMTSSSCTSSFLRNFEQSVNTPCSSQYSVDGRDGEEEAQDAFTNEFRRMKLRGEFPCKLCSAVFPNLRALKGHNRYHLSEVGAAGPFRCNMCPYAVCDKAALVRHMRTHNGDRPYECAVCNYAFTTKANCERHLRNRHGKTSRDDVKRAIVYHPAEDASCEENKSRTDADILTELSGYRCPTPTEHSSSASSSSQLKHMLLAEPTPAVKVTATTAAAAAAAATTSMQQQPLKIQVKSLDQLVDKPLPALDLSMDALDLSKKPAQLLAEQREQREQLERHELLLQQQQHQQQQQQQQQQQQQQQQQQQQLFGAGDAAAQYMQQLLRSFMLQQSPGFPFFGFMAPPPPTAAAAADKSMPTNPTAAAAAAAAAAASATAATIAALPLSLPVPLPAGGPVKMVIKNGVLMPKQKQRRYRTERPFACEHCSARFTLRSNMERHVKQQHPQFYAHRQRHRSGHHVMRDRAASSSAVQAAAAAQAAAAAAAAAAMSNLSQQQQLQQQQQQQLQHSHHVHAPISEQVKYAILAQQLKARKDTDLLQQALAHGSSSVVTNPLLHFTYNKQQQKQQLSNNTGNSLVLDDDEPPKLIIDEDDEDVDGEGEGEGEDDDDEEEEGDHEFNVDDEEQEDEEMDLDDEHQQHELPHKEDDDDDDDDDDDDNDDATAAAAAAAEASLQQLQATNDKLQSKPIEAAKKAAEIIMEQAIKEGEQLASEKQPRSQSQSRGGNKPATPTTMKTMIAQAESVAKSLKEVASSPFKDESQDLVPVAKLVDNATSNQVSFNSYFRPSDVANHMEQSDEEGLVASGSASESNNSGTEDVTSSSSSCGNDTKKKSAYSLAPNRVSCPYCQRMFPWSSSLRRHILTHTGQKPFKCSHCPLLFTTKSNCDRHLLRKHGNVESAMSVYVPTEDVSEPIPVPKSVEEIELEEQRRRQAAEAEREQIERQKERERELELEREREREQQQLIQQLRQQMAAAAAAVAVAVVTAPAHPAAPQPAQSPPGLEASSDLPYKCHLCEFSFGERLQCLEHIKQLHSHEFALLLAKGAIETDGQLQHQQLPVAAGGASHSDDEAAAVGTRSGKYPDYSNRKVICAFCVRRFWSTEDLRRHMRTHSGERPFQCEICLRKFTLKHSMLRHMKKHSGRSHNAGELDHQSDCSDDEQMLPCSPPSTPTPTNNNNNNNNTCQNNNNNNNNSSNNNNNNSNSKQVLRELLGKANEWRVSRLGEHKENIAEATTTPSAATAAAAATAAAAAAAAATAVASGDLIGNLLGISDQGILNKLLSSPDEAAKLLGVEK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00535518;
90% Identity: iTF_00535518;
80% Identity: -