Ddem015146.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila demipolita
Gene Symbol
ftz-f1
Assembly
GCA_035042405.1
Location
JAWNLI010000491.1:156348-167555[-]

Transcription Factor Domain

TF Family
SF-like
Domain
zf-C4|SF-like
PFAM
AnimalTFDB
TF Group
Zinc-Coordinating Group
Description
The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 2 2 1.7e+04 -11.6 27.3 48 159 27 146 4 198 0.48
2 2 1.8e-87 1.6e-83 281.4 8.7 1 408 325 767 325 769 0.81

Sequence Information

Coding Sequence
ATGTTATTAGAAATGGATCAACAACAGGCGACTGTACAGTTTATATCATCGCTGAATCTGTCGCCGTTTAGCATGCAACtcgaacaacagcagccagcgaGTCCGGCGCACAGCAACACTAACAACgctaacaataacagcagcaacaacaacaacaacagcagcagtaatagcaacaacaacaacaacgataacgaTACAAATGCATTAAGCAATTCCGATAACGATTACAGTGCATACACGCTGCAACTGGGCagtcatcagcagcaacagcaacactcaCATCACACtcaccaccagcaacagcagcaacaacaacaacagcaacagcattaccaacagcaacaacaacagaatattgccaacaacaattcgaATGCAGCGGCGAACCAATTCAATGGTTCCTCCTATtcgtatatatacaatttcgATTCACAGTACATATTCCCGACAGGCTATCAGGAAACGAATTCATCCCATTCACAGCAAAGTGCAAGTGGAGCTGGCAACGCCGCATCAGCTGGCAACTCTGGCCAGCTCCTAAACAATGGAAGCAGCAGCTCGACAGGTAATAGTTATATGCTGTTGCCACCAGGCGCTGGTGGAACCTCAGCATCTGCCGCTGCCCATTTGTCCGGCAATGTGGGTGGCAATCCGGCGACGGGCGTAAGCGGAACTGCAGCCGGAGGTGGCCATCATGGCGGCACCAGCGCTAGTTCTGGCGGTGGCGAAGCCATCGATTTTAAGCATCTGTTCGAGGAGTTGTGCCCCGTCTGCGGAGACAAGGTAAGCGGCTATCACTACGGCCTGCTCACCTGCGAGTCCTGCAAGGGCTTTTTTAAGCGCACCGTTCAAAACAAAAAGGTCTACACTTGCGTGGCGGAGCGGTCCTGCCACATCGACAAGACGCAACGCAAACGTTGTCCCTATTGTCGATTCCAAAAGTGCCTGGAGGTGGGCATGAAACTAGAGGCGGTTCGAGCGGACAGGATGCGTGGTGGTCGCAATAAATTTGGACCCATGTACAAACGTGATCGGGCGCGAAAACTGCAAGTGATGCGTCAGCGACAATTAGCGCTGCAGGCGTTGCGCAGTTCGATGGGCACGGACATAAAGCCGACGCCTCTCTCGCCGGGCTATCAGCAAGCATAtccaaatatgaatattaagcAGGAAATTCAAATACCTCAGGTATCCTCACTCACACAATCGCCAGACTCATCACCCAGTCCCATTGCTATTGCCTTGGGTCAGGTGAATGCAAGCGGTAGCGGAGTGATAGCCACGCCGATCAATGCCGGCAACGGCAATGGTGGTTCTTCacttggcaatggcaacaaccacaccaacaacaacggcagcagcggTACAGGCAGCGGAAGCGGGGGAGGAGGGGCTGGTGGAGGAGGCTCCAATAGTGGTGGGAACAACATCGTCGCCGATGGCCTGCAACGCAATGCAAAcagtagcaatagcaatagcaacagcagctgccacgaTATTGGCACTGGATCTCTGCAAAACTCAGCCGAAGCGAAACTGTGCTTTGATTCAGGCACACATCCATCAAGCACAGCCGACGCGCTTATTGAGCCCCTGAGgGTCTCACCAATGATACGCGAGTTTGTGCAATCGATCGATGATCGGGAGTGGCAAACGCAACTTTTTGCCCTACTGCAGAAGCAGACGTACAATCAAGTTGAAGTGGATCTCTTTGAGTTAATGTGTAAAGTGCTTGATCAGAATCTATTCTCACAAGTGGATTGGGCAAGAAACACCGTCTTCTTTAAGGATTTAAAGGTTGACGATCAGATGAAGCTGCTTCAGCATTCTTGGTCTGATATGCTCGTGCTGGATCATTTGCATCATCGCATTCACAACGGTCTGCCCGATGAGACTCAGCTGAATAACGGTCAGGTCTTCAATTTGATGAGTCTCGGTCTACTGGGTGTGCCACAGCTGGGTGACTATTTCAACGAACTGCAGAATAAACTGCAGGAACTGAAGTTCGACATGGGCGACTATGTTTGCATGAAATTCCTAATACTACTAAATCCAGATGTGCGAGGCATTGTAAACAAGAAGACCGTCTTGGAGGGACATGAGAATGTTCAGGCCGCTCTGCTGGATTACACACTGACATGCTATCCTTCAGTTAATGACAAATTCAGGAGGCTACTGAACATCCTTCCGGAAATTCATGCAATGGCCGCACGGGGCGAGGAACACCTTTACTCAAAACATTGTGCTGGCAGTGCGCCCACACAGACGCTGCTCATGGAGATGTTACATGCAAAGCGGAAAGTGTAA
Protein Sequence
MLLEMDQQQATVQFISSLNLSPFSMQLEQQQPASPAHSNTNNANNNSSNNNNNSSSNSNNNNNDNDTNALSNSDNDYSAYTLQLGSHQQQQQHSHHTHHQQQQQQQQQQQHYQQQQQQNIANNNSNAAANQFNGSSYSYIYNFDSQYIFPTGYQETNSSHSQQSASGAGNAASAGNSGQLLNNGSSSSTGNSYMLLPPGAGGTSASAAAHLSGNVGGNPATGVSGTAAGGGHHGGTSASSGGGEAIDFKHLFEELCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNKKVYTCVAERSCHIDKTQRKRCPYCRFQKCLEVGMKLEAVRADRMRGGRNKFGPMYKRDRARKLQVMRQRQLALQALRSSMGTDIKPTPLSPGYQQAYPNMNIKQEIQIPQVSSLTQSPDSSPSPIAIALGQVNASGSGVIATPINAGNGNGGSSLGNGNNHTNNNGSSGTGSGSGGGGAGGGGSNSGGNNIVADGLQRNANSSNSNSNSSCHDIGTGSLQNSAEAKLCFDSGTHPSSTADALIEPLRVSPMIREFVQSIDDREWQTQLFALLQKQTYNQVEVDLFELMCKVLDQNLFSQVDWARNTVFFKDLKVDDQMKLLQHSWSDMLVLDHLHHRIHNGLPDETQLNNGQVFNLMSLGLLGVPQLGDYFNELQNKLQELKFDMGDYVCMKFLILLNPDVRGIVNKKTVLEGHENVQAALLDYTLTCYPSVNDKFRRLLNILPEIHAMAARGEEHLYSKHCAGSAPTQTLLMEMLHAKRKV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00485910;
90% Identity
iTF_00553087;
80% Identity
iTF_00498926;