Ddem007037.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila demipolita
Gene Symbol
Hr39
Assembly
GCA_035042405.1
Location
JAWNLI010000069.1:2374856-2377940[+]

Transcription Factor Domain

TF Family
SF-like
Domain
zf-C4|SF-like
PFAM
AnimalTFDB
TF Group
Zinc-Coordinating Group
Description
The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 3 0.57 4.9e+03 -3.5 17.7 31 206 27 218 20 224 0.58
2 3 2 1.7e+04 -11.2 30.1 25 98 210 306 198 385 0.32
3 3 1.7e-100 1.4e-96 324.3 10.8 1 408 516 903 516 903 0.91

Sequence Information

Coding Sequence
ATGCCAAATATGTCAAGCATTAAGACGGAGCAGAGTGTTTCACCCGGTGCCAGTGGCAGCTATCAGCTGCCTGAAAACATGTCGACGGCGACAGTGATGCCAGCGTCGCAgccgctgcagcaacagcagcagcagcagcagcagcagcgtcacaATGTCTCCGTGACGAATATCAAATGTGAACTGGACGAGCTGGCGACGCCAACGAATGGCAACCTGGTGCCGGTCATAGCCAactataataatcataatcacaatcacaatcacaatcatAGCGGCAGCCTGCGCATTCCCCTCGGTGGCAATGGGGATGAGTCCGACTCGGATGCGGAGCTGGCCAACATTGAGAATCTGAAGGTGCGGCGACGTGCGGCAGACAAGAATGGTCCGCGTCCCATGTCCTGGGAGGGTGAGCTGAGCGAGAACGAAACGAATGGCGGCGCCGCCGGCGATGAGGAGGAGCTCATGGAAACGGAAACGGTGATCAAGAGCGAGgtaagcagcagcaccagcagcagcagcagtgccacAACGTTGGCCAGCAGTCAAGTGAACGCCATGTTGCAGCCCATCAAAACCGAACTGGAGCACATAGCCGGTgagatgcaacagcagcagcagcagcagcaacaacaacaacaacaacaacaacagcagcagcagcagcagcagcaacaacagcagcagcaacaacaacaacagcagcagcaactgcaacagcaacaactgcagcagcaacagcttcagctgcaacagcaacaacaattgctacCACTGAAGCAACAGAGCTATGCACCGaacaacaaactgaaactggCGCCAACGCAAAGTGATCccatcaatttaaaatatgagccaacgacaacgacaacatcatCGCTGCTCTGCGACAGGATCAAGTCGAATAGTGGCGGCcatttgccgctgctgcccgCCAATCCCAGTCCCGATTCTGCCATACATTCCGTCTATACGCACAGCAGCCCCTCCCAATCCCCGTTGACGTCCCGCCACGCCCCCTACACGCCATCGCTGAGCAGAAACAACAGCGATGCGTCTCACAGCAGctgctacagctacagctccGAATTCAGTCCCACCCACTCTCCGATTCAGGCGCGTCATGCGCCACCCGCTGGCGTTGCTGCTCTGTTTACGGGCAATGCAAATGGCGGTGCACTGCATCATCATAGTGTGCTCTATCGGCCACTCAATGTGGATGCCGCACAGGAGGCGCAAAACCTGAGCATGGATGCGGGTGGTGCTGCGCTGGATGCCAGTGCCACGTTGGCCGCCTCGCCGGCGGGCATCTCGCGTCAGCAGCTGATCAATTCGCCGTGTCCAATTTGTGAGGATAAGATCAGTGGCTTCCACTATGGCATCTTCTCGTGCGAGTCGTGCAAGGGCTTCTTCAAGCGCACCGTCCAGAATCGCAAgaactatgtgtgtgtgcgcggcGGTCCCTGCCAGGTCAGCATATCGACGCGCAAGAAGTGCCCCGCCTGCCGTTTCGAGAAGTGCCTGCAGAAGGGCATGAAACTGGAAGCGATTCGCGAGGATCGCACCCGAGGCGGTCGCTCCACGTATCAATGCTCCTACACGCTACCCAATTCAATGCTTAGTCCGCTGCTCAGTCCGGATCAGGcggcagccgccgccgccgttgtcaatcagcagcagcagcagcaacaccaacagcagcgacttcaacagcatcagcagcaacaacaacagcaacaacagcagcagcagcagcaacatggtCCACTCAATGGctttggtggtggtggctcCAACTCGCTGCCAGCGAGTCCCAGTCTCGGCGGGGCATCCATCAAGACGGAGCTAGCGGAGCAGCTTAATCATCATACGTTATCATTAACGCGAGCCTCAAGCATTCCAGCCCTGCTGCAGGAAATCATGGATGTTGAACATCTCTGGCAATATACAGATGCGGAATTGGCACGCATTAATCAGCCGCTGTCCTCATTTGCAACTGGTGGCTCATCGTCGAGCGGCACTGGCGGTTCAAGTTCCGCCGGACAGCATACGGGCAATGCACAACAAATGACCAATCCACTGCTGGCCAGTGCTGGTCTCTCATCCAACGGCGAGAACGCTAATCCCGATCTGATTGCGCACCTCTGCAACGTGGCCGATCATCGCCTCTACAAGATCGTCAAGTGGTGCAAAAGTTTGCCGCTCTTCAAGAACATCTCGATTGACGATCAGATCTGCCTGCTCATCAACTCGTGGTGTGAACTGTTGCTCTTCTCCTGCTGTTTTCGTTCCGTCGATACGCCCGGCGAGATCAAGATGTCACAGGGCAGAAAGATTACGCTGGCACAGGCTAAAACCAATGGCTTGCAGGCTTGCATTGAGCGCATGTTGAATCTGACGGATCATTTGCGTCGCCTGCGCGTGGATCGCTACGAATATGTTGCCATGAAGGTAATCGTGCTGCTGCAGTCCGACACAACGGAGCTGCACGAGGCAGTCAAGGTGCGCGAGTGCCAGGAGAAGGCGCTGCAGGGCTTGCAGGCCTACACACTGGCCCATTATCCCGATACGCCGTCCAAGTTTGGTGAGCTGCTCCTGCGCATACCCGATCTGCAGCGCACGTGTCAGCTGGGCAAGGAAATGCTGACGATCAAAACGCGTGATGGTgcagattttaatttgctgaTGGAACTGCTGCGCGGAGAACATTGA
Protein Sequence
MPNMSSIKTEQSVSPGASGSYQLPENMSTATVMPASQPLQQQQQQQQQQRHNVSVTNIKCELDELATPTNGNLVPVIANYNNHNHNHNHNHSGSLRIPLGGNGDESDSDAELANIENLKVRRRAADKNGPRPMSWEGELSENETNGGAAGDEEELMETETVIKSEVSSSTSSSSSATTLASSQVNAMLQPIKTELEHIAGEMQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQLQQQQLQQQQLQLQQQQQLLPLKQQSYAPNNKLKLAPTQSDPINLKYEPTTTTTSSLLCDRIKSNSGGHLPLLPANPSPDSAIHSVYTHSSPSQSPLTSRHAPYTPSLSRNNSDASHSSCYSYSSEFSPTHSPIQARHAPPAGVAALFTGNANGGALHHHSVLYRPLNVDAAQEAQNLSMDAGGAALDASATLAASPAGISRQQLINSPCPICEDKISGFHYGIFSCESCKGFFKRTVQNRKNYVCVRGGPCQVSISTRKKCPACRFEKCLQKGMKLEAIREDRTRGGRSTYQCSYTLPNSMLSPLLSPDQAAAAAAVVNQQQQQQHQQQRLQQHQQQQQQQQQQQQQQHGPLNGFGGGGSNSLPASPSLGGASIKTELAEQLNHHTLSLTRASSIPALLQEIMDVEHLWQYTDAELARINQPLSSFATGGSSSSGTGGSSSAGQHTGNAQQMTNPLLASAGLSSNGENANPDLIAHLCNVADHRLYKIVKWCKSLPLFKNISIDDQICLLINSWCELLLFSCCFRSVDTPGEIKMSQGRKITLAQAKTNGLQACIERMLNLTDHLRRLRVDRYEYVAMKVIVLLQSDTTELHEAVKVRECQEKALQGLQAYTLAHYPDTPSKFGELLLRIPDLQRTCQLGKEMLTIKTRDGADFNLLMELLRGEH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00575636;
90% Identity
iTF_00595983;
80% Identity
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