Dcyr012574.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila cyrtoloma
Gene Symbol
RREB1
Assembly
GCA_035042485.1
Location
JAWNLH010000885.1:10708909-10715703[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 13 0.037 2.4 8.7 0.8 1 21 270 290 270 292 0.93
2 13 0.00034 0.022 15.1 0.2 1 23 302 324 302 324 0.98
3 13 0.00025 0.017 15.5 7.2 1 23 330 352 330 352 0.98
4 13 0.24 16 6.1 1.7 2 20 583 601 583 603 0.93
5 13 0.016 1 9.8 0.2 1 23 753 775 753 775 0.97
6 13 1.3e-05 0.00082 19.6 0.7 1 23 785 807 785 807 0.99
7 13 0.00085 0.055 13.9 2.0 1 23 813 836 813 836 0.97
8 13 0.003 0.2 12.1 2.0 1 23 1117 1140 1117 1140 0.95
9 13 8.8e-05 0.0057 17.0 0.3 2 23 1535 1556 1534 1556 0.97
10 13 0.15 9.7 6.8 6.3 1 23 1562 1585 1562 1585 0.97
11 13 9.6 6.2e+02 1.1 3.4 1 23 1701 1724 1701 1724 0.78
12 13 0.0086 0.56 10.7 0.5 3 23 1786 1806 1784 1806 0.96
13 13 0.0014 0.089 13.2 4.8 1 23 1812 1834 1812 1834 0.99

Sequence Information

Coding Sequence
ATGCTcgccacacagcagcagcagcaacagcagcagcagcaacaacaacagcaacaatcgcaCACAGcatctgcaactgcagcagcagcagcaacacatgAGGATGCCCGGGATTTGGGGTTAATTGAGGCGCGACAGCGTCGCGAATCGAGCACCTCAGAATCCTCGCTGGAGCATTTGGATTTGGGTCGCACGCCCAAaaagttgagcagcagcagcggcgcacCGCTGCCGACGTCGACGCCGCACGACACAGCAGTGACAGCGACGTCGCGCAAGCGCAAACTGCGacagcaacaccaccagcagcagcagcagcaacagttgccactcTCCGatgaggagcaacagcaacagcagcagcagctgttggacTCATCGGCGCAGCGACCGCGTCACAAGCAGCGACGCAGCgccgttgctgccgctgccagcgCCAGCATCGTTGTCGACTACAGCGCCAGCGGCGACGCCAGCTCGCTGCGCAAAAAGTTTCGACTGAAtcgcagcagcgccagcagcaatgCCGCCAACGGTGATTTATCCGAGTCGGGTTTCGTTGATGGCAGCGCCCTCAGTGGCTATCTGcttggcagcaacagcaacaacaacaacaataataataataacaacaacaacaacaacaatatcagtaatagtagcagcagcagcagcgcagtcgctcagtcagcagcagcagcgtcggcAGCGCAGCATGCGTCAAGCGTTAGCAGCTCGGGCGGCTCCTCGCCACAGGGCCTCTCGAGCGCCGAGTCGGGCATCGGTGCCGGCGATGAGCACATGAAATATCTGTGCCCCATTTGCGAGGTCGTCTCGGCCACGCCCCACGAATTCACCAATCACATTCGCTGCCACAACTACGCCAACGGCGACACCGAGAACTTCACCTGCCGCATCTGCTCCAAGGTGCTCTCGTCGGCATCCTCGCTGGACCGGCATGTCCTGGTGCACACTGGAGAGCGTCCGTTCAACTGTCGCTATTGCCACTTGAACTTCACAACCAATGGGAACATGCACCGACACATGCGCACCCACAAGCAACATCAggcgtcgcagcagcagcagcagcaacagcagcagcactcgcaacagcagcaatccacacaacagcagcaacaggcacagtcgcagtcgcagcaacaacaacagcgacgccAGCAACATGCGggtggagcaggagcaactgGCTCGGTATCGGGATCAGCACAGTTGTTGACGACGCGAGCGGAGAGCTATGAGAGTGATGCCAGCTGCTCGACGGATGTGTCCAGTGAGCTGAAcagtcacagcagcaacagcaatcaatccaaccacaacaacaacaacaacaacaatagccacaaaacgaacaacaataacaacaacaacaacaacaatgaggaTGAGCTCGAGCTGGAGGATGAGCAGCTGGTTCTGAGCAGCAAACAGCGACGCCACAAGGCAGCcctgaacaacaacaatataattaGGGATGAGGAGCACGAGAATCGGCCGGATGATGATTCGGATGTGGATAGCGCTGATAGCGTTGCCCAGGTGATAACAAGCACACCGGATGTGGCCACGCTGCTCGCTTCGGGCGGCACCTCGCCCACCCACTCGCATTCGGAATCGCATTCACCgcccctgctgctgcagagcTGCCCGGCCTGCAATTCGGGTGAATTTGAATCTGTGCCAGCGTTGTGCGCCCATCTGGATGCCGAGCACGCGGACATACCGGCCAAGTGTCGCGAGTGCGAGGTGATCTTTGCCACACATCGACAGCTGCAGGCGCACAGCTGTCGAGGATTGCCGCCGCTGCTTGGTGTGAGCTCATCGCCACTGCACAAGCAGGAGGAGAGCGAACTGgaggagcagcaccagcaccagcagcagcagcacgaggaggaggaccacgaacagcagcagcacaagcaggaggaacaggagcaggcgGAGCAGCGCGAATGCGAAGATTTCTTCCAGCAGCTGTATCTGAAGAATAAATCGTCAGCAACGCTGCTTCCCTCACCGATCAAACATGAGCCGGCGGACCAGCGACAGGATCTGGCCGATATTCAAAGCATACTCAATATGACCAGTTCCAGCTGCACCTCGAGTTTCCTGCGCAATTTCGAGCAGTCGGTGAACACGCCCTGCTCCAGCCAATATAGCGTCGATGGACGCGATGGCGAGGAGGAGGCCCAGGATGCCTTCACCAATGAATTCCGGCGAATGAAACTGCGCGGTGAGTTCCCCTGCAAGCTGTGCACCGCCGTCTTTCCCAATCTGCGTGCGCTCAAGGGCCACAATCGCTACCATCTGTCGGAGGTGGGCGCCGCTGGTCCATTCCGTTGCAACATGTGTCCCTATGCCGTCTGCGACAAGGCGGCGCTCGTCCGGCACATGCGCACCCACAACGGCGATCGGCCTTACGAGTGCGCCGTCTGCAATTATGCGTTCACCACCAAGGCGAACTGTGAGCGGCATTTGCGCAATCGACATGGCAAGACCAGTCGCGAGGATGTGAAACGTGCGATTGTCTATCATCCGGCCGAAGATGCCAGCTGCGAGGAGAACAAATCGCGGACCGAAGCCGATATCCTAACGGAGCTGAGCGGCTATCGTTGTGCAACACCCACGGAGCACAGCTCCTCGGCCAGCTCCTCGTCACAGCTGAAGCACATGTTGCTGGCGGAGCCGACGCCGGCCGTAAaggtagcagcaacaacagctgcagtagcagcggcagcagcagcaacaacatcgctGCCACAACAACCGCTCAAGATTCAGGTGAAGAGCTTGGATCAGCTGGTGGATAAGCCACTGCCAGCACTCGATCTCAGCATGGATGCGCTCGACCTGAGCAAGAAGCCCGCCCAGCTGCTGGCCGAGCAACGGGAGCAAAGGGAGCAGCTCGAAAGACACGAATtggtgctgcagcagcaacagcagcagcaacaacaacagctgcagcagcagcagcaacagcagcagcagcaacaaatgtttGGGGCTGGCGATGCAGCTGCTCAGTATATGCAACAGCTGTTGCGCAGCTTCATGCTCCAGCAATCACCCGGTTTTCCTTTCTTTGGGTTTATGGCGCCACCGCCACCAACAgcggtagcagcagcagcagcagcagcaacagcagcagacaaatcaatgacaacaaatccagcagcagcagcagcagccggcgcaacagcagcaacaattgctgcaatGCCACTGTCGCTGCCTGTGCCACTGCCCGCTGGTGGTCCCGTCAAGATGGTCATCAAGAATGGCGTCCTGATGCCCAAGCAGAAGCAGCGCCGCTATCGCACCGAGCGTCCCTTTGCCTGCGAGCATTGCTCGGCCCGCTTCACCCTGCGCTCCAACATGGAGCGCCAtgtgaagcagcagcatccacagtTCTATGCGCAGCGCCAGCGACACCGCAGCGGTCATCATGTGATGCGTGAACGGGCTGCATCCTCGAGTGCTGTCCAAGCGGCAGCCGCTGCAcaggcagcggcggcagcagcagccgccgccgccgcagcaatGAGTAAtctcagccagcagcaacagttgcagcactCGCATTCACATCATGTCCATGCGCCAATCTCGGAGCAGgtgaaatatgcaattttggCGCAGCAATTGAAGGCGCGCAAGGATACCGATTTGTTGCAACAGGCACTGGCACATGGCTCCAGCAGTGTTGTCGCCAATCCGCTGTTGCATTttagctacaacaacaacaacaacagcagcagcaacagcatcagcaacaagcagcagcaacaacagttgagCAACAACACTGGCAACTCTTTGGTGCTGGACGACGATGAGCCGCCCAAGCTGATCATTGACGAGGATGACGAGGATGTGGATGGCGaggacgatgaggatgaggaggaggagcaggattttgatgttgatgaggaggagcaggaggatgAAGAGATGGACTTGGACGatgagcatcagcagcagctgcacgaggaggatgatgatgatgatattgatgatgatgatgcagcagcaacagcagcaacagcagcagcagctgcagctgcagcagaggcgtcgcagcaacaattgcagccaACCAAGGACAAGCTGCAAACCAAGCCAATTGAGGCGGCCAAAAAGGTAGCGGAAACCATATTGGAGCAGGCAATCAAAGAGCGCGTGGAGAAAGCCGCCGAGAAACAGCCGCATCCTCAATCGGAGTCCGTGGGCGGCAATAAGCCGGCGACGCCGACAACAATGAAAACGATGATTGCACAAGCGGAATCGGTGGCCAAGTCCTTGAAGGAGGTGGCCAGTTCACCGTTCAAGGATGAATCTCAGGATCTGGTGCCGGTGGCCAAACTGGTGGACAATGCGACCAGCAATCAGGTGTCGTTCAACAGCTATTTCCGTCCCAGCGACGTCGCCAATCACATGGAGCAGAGCGACGAGGAGGGTCTCGTTGCCAGCGGCAGCGCCAGCGAGAGCAACAATTCCGGCACCGAGGAtgtgaccagcagcagcagcagctgcggcaatGACACCAAAAAGAAGTCCGCCTACAGCCTGGCACCGAATCGTGTCAGCTGCCCGTATTGCCAGCGCATGTTCCCCTGGAGCAGCTCGCTGCGTCGCCACATCCTGACGCACACCGGCCAGAAGCCGTTCAAGTGCTCCCACTGCCCGCTGCTGTTCACCACGAAGAGCAACTGCGATCGCCATCTGTTGCGCAAGCATGGCAACGTTGAGTCCGCCATGTCCGTCTATGTGCCCACCGAGGATGTCAGCGAACCGATACCCGTGCCCAAGTCCGTCGAGGAGATTGAGCTCGAGGAGCAGCGACGTCGCCAGGCGGCCGAAGCCGAACAGGCCGAGCGTGAGCAGCGCGAGCGCCAAAAGGAGCGCGAACGTGAGCTGGAAttggaacgggaacgggaacgggaacacCAACAGTTGATACAACAGTTGCGCCAACAAATGGCCGCTGCCGCAGCGGCTGCTGTCGCCGCCGTTGCTGCGCCAACGCATCCACCACCGCCAGCCCAATCGCCACCGGGCCTGGAGGCGAGCAGTGATCTGCCCTACAAATGCCATCTGTGCGAGTTCTCATTCGGCGAGCGGCTTCAGTGTCTCGAGCACATCAAGCAGCTGCACGCACACGAGTTCgcactgctgctggccaagggAGCCATCGAAACGGATGCACAGCtccagcaccaacagcagcagcagcaacaattgccagCGGCTGGAGGTGCTCCACATTCGGATGATGAGGCTGCCGCTGTCGGCACCAGATCGGGCAAATATCCCGACTATAGCAATCGTAAAGTGATTTGCGCATTTTGCGTGCGTCGCTTCTGGTCAACGGAGGATCTGCGGCGACATATGCGCACCCATTCCGGTGAGCGTCCGTTCCAGTGCGAGATCTGCTTGAGGAAGTTCACATTGAAGCACAGCATGCTGCGACACATGAAGAAGCACAGTGGACGCAGTCACAATGGTGGCGAGCTCGACCATCAATCCGATTGCTCCGACGATGAGCAGCTGTTGCCCTGCTCCCCACCCTCAACGCCAACGcccactaacaacaacaacaacaacaacacttgccagaacaacaacaacaacagcaacaacaataacaacaacaatagcaatggcAAGCAGGTGCTGCGCGAGCTGCTGGGCAAGGCGAACGAGTGGCGAGTGAGTCGCCTGGGCGAGCACAAGGAGAACATTGccgaggcaacaacaacaccctcagcagcaacagcagcagcggcagcaacagctgcagcagcagcagcagcagcagctgtggccaGTGGCGATCTAATTGGTAATCTGTTGGGGATCAGTGATCAGGGCATACTAAACAAGCTGCTCTCCTCACCAGACGAAGCTGCCAAGCTGCTGGGAGTGGAGAAGTAA
Protein Sequence
MLATQQQQQQQQQQQQQQQSHTASATAAAAATHEDARDLGLIEARQRRESSTSESSLEHLDLGRTPKKLSSSSGAPLPTSTPHDTAVTATSRKRKLRQQHHQQQQQQQLPLSDEEQQQQQQQLLDSSAQRPRHKQRRSAVAAAASASIVVDYSASGDASSLRKKFRLNRSSASSNAANGDLSESGFVDGSALSGYLLGSNSNNNNNNNNNNNNNNNISNSSSSSSAVAQSAAAASAAQHASSVSSSGGSSPQGLSSAESGIGAGDEHMKYLCPICEVVSATPHEFTNHIRCHNYANGDTENFTCRICSKVLSSASSLDRHVLVHTGERPFNCRYCHLNFTTNGNMHRHMRTHKQHQASQQQQQQQQQHSQQQQSTQQQQQAQSQSQQQQQRRQQHAGGAGATGSVSGSAQLLTTRAESYESDASCSTDVSSELNSHSSNSNQSNHNNNNNNNSHKTNNNNNNNNNNEDELELEDEQLVLSSKQRRHKAALNNNNIIRDEEHENRPDDDSDVDSADSVAQVITSTPDVATLLASGGTSPTHSHSESHSPPLLLQSCPACNSGEFESVPALCAHLDAEHADIPAKCRECEVIFATHRQLQAHSCRGLPPLLGVSSSPLHKQEESELEEQHQHQQQQHEEEDHEQQQHKQEEQEQAEQRECEDFFQQLYLKNKSSATLLPSPIKHEPADQRQDLADIQSILNMTSSSCTSSFLRNFEQSVNTPCSSQYSVDGRDGEEEAQDAFTNEFRRMKLRGEFPCKLCTAVFPNLRALKGHNRYHLSEVGAAGPFRCNMCPYAVCDKAALVRHMRTHNGDRPYECAVCNYAFTTKANCERHLRNRHGKTSREDVKRAIVYHPAEDASCEENKSRTEADILTELSGYRCATPTEHSSSASSSSQLKHMLLAEPTPAVKVAATTAAVAAAAAATTSLPQQPLKIQVKSLDQLVDKPLPALDLSMDALDLSKKPAQLLAEQREQREQLERHELVLQQQQQQQQQQLQQQQQQQQQQQMFGAGDAAAQYMQQLLRSFMLQQSPGFPFFGFMAPPPPTAVAAAAAAATAADKSMTTNPAAAAAAGATAATIAAMPLSLPVPLPAGGPVKMVIKNGVLMPKQKQRRYRTERPFACEHCSARFTLRSNMERHVKQQHPQFYAQRQRHRSGHHVMRERAASSSAVQAAAAAQAAAAAAAAAAAAMSNLSQQQQLQHSHSHHVHAPISEQVKYAILAQQLKARKDTDLLQQALAHGSSSVVANPLLHFSYNNNNNSSSNSISNKQQQQQLSNNTGNSLVLDDDEPPKLIIDEDDEDVDGEDDEDEEEEQDFDVDEEEQEDEEMDLDDEHQQQLHEEDDDDDIDDDDAAATAATAAAAAAAAEASQQQLQPTKDKLQTKPIEAAKKVAETILEQAIKERVEKAAEKQPHPQSESVGGNKPATPTTMKTMIAQAESVAKSLKEVASSPFKDESQDLVPVAKLVDNATSNQVSFNSYFRPSDVANHMEQSDEEGLVASGSASESNNSGTEDVTSSSSSCGNDTKKKSAYSLAPNRVSCPYCQRMFPWSSSLRRHILTHTGQKPFKCSHCPLLFTTKSNCDRHLLRKHGNVESAMSVYVPTEDVSEPIPVPKSVEEIELEEQRRRQAAEAEQAEREQRERQKERERELELEREREREHQQLIQQLRQQMAAAAAAAVAAVAAPTHPPPPAQSPPGLEASSDLPYKCHLCEFSFGERLQCLEHIKQLHAHEFALLLAKGAIETDAQLQHQQQQQQQLPAAGGAPHSDDEAAAVGTRSGKYPDYSNRKVICAFCVRRFWSTEDLRRHMRTHSGERPFQCEICLRKFTLKHSMLRHMKKHSGRSHNGGELDHQSDCSDDEQLLPCSPPSTPTPTNNNNNNNTCQNNNNNSNNNNNNNSNGKQVLRELLGKANEWRVSRLGEHKENIAEATTTPSAATAAAAATAAAAAAAAAVASGDLIGNLLGISDQGILNKLLSSPDEAAKLLGVEK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00535518;
90% Identity
iTF_00525357;
80% Identity
-