Dcyr010881.1
Basic Information
- Insect
- Drosophila cyrtoloma
- Gene Symbol
- ftz-f1
- Assembly
- GCA_035042485.1
- Location
- JAWNLH010000830.1:1310514-1326662[+]
Transcription Factor Domain
- TF Family
- SF-like
- Domain
- zf-C4|SF-like
- PFAM
- AnimalTFDB
- TF Group
- Zinc-Coordinating Group
- Description
- The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 4 3 1.7e+04 -12.0 29.6 37 160 20 159 4 170 0.51 2 4 0.99 5.6e+03 -3.7 15.4 42 129 90 163 83 199 0.39 3 4 2.3e-19 1.3e-15 57.7 0.3 1 78 333 409 333 439 0.75 4 4 3.7e-72 2.1e-68 231.6 1.3 157 408 531 775 493 777 0.91
Sequence Information
- Coding Sequence
- ATGTTATTAGAAATGGATCAACAACAGGCGACTGTACAGTTTATATCGTCGCTGAATCTGTCGCCGTTTAGCATGCAACTCGAACAACAGCAGCCCGCGAGTCCGGCGCACAGCAACACTAACAAcgctaacagcaacaacaacaacaatagcagcaacaacaacaacagcagcagtaatagcaacaacaacaacaacaataacaacgataACGATACAAATGCATTGAGCAATTCCGATAACGATTACAGTGCATACACGCTGCAACTGGGCagtcatcagcagcagcagcaacactcacatcacacacatcaccagcagcagcagcaacaacaacagcagcaacagcagcagcattaccaacagcaacaacaacaaaatattgccaacaacaatgcgaaTGCAGCGGCGAACCAATTCAATGCTTCCTCCTATtcgtatatatacaatttcgATTCACAGTACATATTCCCGACAGGCTATCAGGAAACGAACTCATCCCATTCGCAGCAAAGTGCAAATGGAGCTGGCAATGCCGCAGCAGCTGGCAACTCTGGCCAGCTCTTAaacggtggcagcagcagctcgacaGGTAATGGTTACATGCTGTTGCCACCAGGCGCTAGTGGAAcctcagctgctgccgctgctcatATGTCCGGCAATGTGGGCGGCAATCCGGCCGCGGGCGTAAGTGGAACTGCTGCCGGCGGTGGTCATCATGGCGGCACCAGCGCCACTTCTGGCGGTGGCGAAGCAATCGATTTTAAGCATCTGTTCGAGGAGCTGTGCCCCGTTTGCGGGGACAAGGTGAGCGGCTATCACTACGGCCTGCTCACTTGCGAGTCCTGCAAGGGCTTCTTCAAGCGCACCgttcaaaacaaaaaggtcTACACTTGCGTGGCGGAGCGCTCCTGTCACATCGACAAGACGCAGCGCAAACGTTGTCCATATTGTCGATTCCAAAAGTGCCTGGAGGTGGGCATGAAACTAGAGGCGGTTCGAGCGGACCGGATGCGTGGCGGTCGCAATAAATTTGGACCCATGTACAAACGGGATCGGGCGCGAAAACTGCAAGTGATGCGTCAGCGGCAACTGGCGCTGCAGGCGTTGCGCAGTTCGATGGGCACGGACATAAAGCCGACGCCTCTCTCGCCGGGCTATCAGCAAGCATAtccaaatatgaatattaagcAAGAAATTCAAATACCTCAGgTATCCTCACTCACACAATCGCCAGATTCATCACCCAGCCCCATTGCTATTGCCTTGGGTCAGGTGAATGCGAGCGGGGGCGGTGTGATAGCCACGCCGATCAATGCCGGCAACGGCAATGGTGGCTCCTCacttggcaatggcaacagcaacaccaacaacaacggcagcaacggcaCAGGCAGCGGAagcggaggaggagggggtggTGGAGGAGGCACCAATActggtggcaacaacaacgtcacCGATGGCCTGCAACGCAAtggaaacagcagcaatagcaacagcaacagcagctgccacgaAATCGGCACTGGATCTCTACAGAACTCAGCCGAAGCGAAATTGTGCTTCGATTCTGGCACACATCCATCGAGCACAGCCGACGCGCTTATTGAGCCACTGAGggtCTCACCAATGATACGCGAGTTTGTGCAATCGATCGATGATCGGGAATGGCAAACGCAACTTTTTGCGCTACTGCAGAAGCAGACGTACAATCAAGTTGAAGTGGATCTCTTTGAGTTAATGTGCAAAGTGCTTGATCAGAATCTATTCTCACAAGTGGATTGGGCAAGAAACACCGTCTTCTTTAAGGATTTAAAGGTTGACGATCAGATGAAGCTGCTTCAGCATTCTTGGTCCGATATGCTCGTGCTGGATCATTTGCATCATCGCATTCACAACGGTCTGCCCGATGAGACTCAGCTGAATAACGGTCAGGTCTTCAATTTGATGAGTCTTGGTCTACTGGGTGTGCCACAGCTTGGTGACTATTTCAACGAACTGCAGAATAAGCTGCAGGAACTGAAGTTCGATATGGGCGACTATGTTTGCATGAAATTCCTAATACTGCTAAATCCAGATGTGCGAGGCATTGTGAACAAGAAGACCGTCTTGGAGGGACATGAGAATGTTCAGGCCGCGCTGCTGGATTACACACTGACATGTTATCCCTCAGTTAATGACAAATTCAGGAGGCTACTGAACATTCTTCCGGAAATTCACGCAATGGCCGCACGGGGCGAGGAACACCTCTACTCAAAGCATTGTGCTGGCAGTGCGCCCACACAGACGTTGCTCATGGAGATGCTGCATGCAAAGCGGAAAGTGTAA
- Protein Sequence
- MLLEMDQQQATVQFISSLNLSPFSMQLEQQQPASPAHSNTNNANSNNNNNSSNNNNSSSNSNNNNNNNNDNDTNALSNSDNDYSAYTLQLGSHQQQQQHSHHTHHQQQQQQQQQQQQQHYQQQQQQNIANNNANAAANQFNASSYSYIYNFDSQYIFPTGYQETNSSHSQQSANGAGNAAAAGNSGQLLNGGSSSSTGNGYMLLPPGASGTSAAAAAHMSGNVGGNPAAGVSGTAAGGGHHGGTSATSGGGEAIDFKHLFEELCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNKKVYTCVAERSCHIDKTQRKRCPYCRFQKCLEVGMKLEAVRADRMRGGRNKFGPMYKRDRARKLQVMRQRQLALQALRSSMGTDIKPTPLSPGYQQAYPNMNIKQEIQIPQVSSLTQSPDSSPSPIAIALGQVNASGGGVIATPINAGNGNGGSSLGNGNSNTNNNGSNGTGSGSGGGGGGGGGTNTGGNNNVTDGLQRNGNSSNSNSNSSCHEIGTGSLQNSAEAKLCFDSGTHPSSTADALIEPLRVSPMIREFVQSIDDREWQTQLFALLQKQTYNQVEVDLFELMCKVLDQNLFSQVDWARNTVFFKDLKVDDQMKLLQHSWSDMLVLDHLHHRIHNGLPDETQLNNGQVFNLMSLGLLGVPQLGDYFNELQNKLQELKFDMGDYVCMKFLILLNPDVRGIVNKKTVLEGHENVQAALLDYTLTCYPSVNDKFRRLLNILPEIHAMAARGEEHLYSKHCAGSAPTQTLLMEMLHAKRKV
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00485910;
- 90% Identity
- iTF_00553087;
- 80% Identity
- iTF_00498200;