Basic Information

Insect: Drosophila cyrtoloma
Gene Symbol: Hr39_1
Assembly: GCA_035042485.1
Location: JAWNLH010000675.1:3154473-3157919[-]

Transcription Factor Domain

TF Family: SF-like
Domain: zf-C4|SF-like
PFAM: AnimalTFDB
TF Group: Zinc-Coordinating Group
Description: The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 3 3 1.7e+04 -6.0 19.3 39 204 40 222 21 227 0.49

2 3 3 1.7e+04 -10.3 27.9 24 149 215 341 202 376 0.31

3 3 2.6e-99 1.5e-95 321.0 9.2 1 408 511 886 511 886 0.84

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	3	3	1.7e+04	-6.0	19.3	39	204	40	222	21	227	0.49
2	3	3	1.7e+04	-10.3	27.9	24	149	215	341	202	376	0.31
3	3	2.6e-99	1.5e-95	321.0	9.2	1	408	511	886	511	886	0.84

Sequence Information

Coding Sequence: ATGCCAAATATGTCGAGCATTAAGACGGAGCAGAGTGTTTCACCCGGTGCCAGTGGCAGCTATCAGCTGCCCGTTAACATGTCGACGGCGACAGTGACGCCagcgtcgcagcagcaacagcagcagcagcaacagcagcagcaacagcagcagcaccagcgcCACAATGTCTCCGTGACGAATATCAAATGTGAACTGGACGAGCTGGCGACGCCAACGAATGGCAACCTGGTGCCGGTCATAGCCAactataataatcataatcacaatcacaatcacaatcacagcGGCAGCTTGCGCATTCCCCTCGGCGGCAATGGGGATGAGTCCGATTCGGATGCGGAGCTGGCCAACATTGAGAATCTGAAGGTGCGGCGACGTGCGTCAGACAAGAATGGTCCGCGTCCCATGTCCTGGGAGGGTGAGCTGAGCGAGAACGAAACGAATGGCGGCGCCGTCGGCGATGAGGAGGAGCTCATGGAAACGGAAACGGTGATCAAGAGCGAggtgagcagcagcaccagcaccagcagcagcagcagtgccacAACAATGGCCAGCAGTCAAGTGAACGCCATGTTGCAGCCCATCAAAACCGAACTGGAGAACATAGCCGGCgagatgcaacagcaacagcagcagcagcaacagcagcagcaacaacaacagcagcagcaacaacaacagcagcagcagcagcaacagcagcagcagcagcaacaactccagctgcaacaacaacagcaacaattgctgccacTGAAGCAACAGAGCTATGCACCGAACAACAAGCTGAAATTGGCGCCGACGCAAAGTGATCccatcaatttgaaatatgagccgacgacaacgacaacatcgtCGCTGCTCTGCGACAGGAGCAAGTCGAATAGTGGCGGCcatttgccgctgctgcccgCCAATCCCAGTCCCGATTCTGCCATACATTCCGTCTATACGCACAGCAGCCCCTCCCAATCGCCGCTGACGTCCCGCCACGCCCCCTATACGCCCTCGCTGAGCAGGAACAACAGCGACGCGTCGCACAGTAGttgctacagctacagctccGAATTCAGTCCCACCCACTCACCCATTCAGGCGCGTCATGCGCCACTCGCCGGCGTCGCTGCCTTGTTCACGGGCAATGCAAATGGCGGTGCACTGCATCATCACAGTGTACTCTATCGGCCACTCAATGTGGATGCCGCACAGGAGGCACAAAATCTGAGCATGGACGCGGGTGGTGCATCATTGGATGCCAGTGCCACGTTGGCTGCCTCGCCGGCGGGCATCTCGCGCCAGCAGCTAATCAATTCGCCGTGTCCGATTTGTGGGGATAAGATCAGTGGCTTCCACTATGGCATCTTCTCGTGTGAGTCGTGCAAGGGCTTCTTCAAGCGCACCGTCCAGAATCGCAAgaactatgtgtgtgtgcgaggcGGTCCCTGCCAGGTGAGCATCTCGACGCGCAAAAAGTGCCCCGCCTGCCGTTTCGAGAAGTGCCTGCAGAAGGGCATGAAATTGGAGGCGATACGCGAGGATCGCACACGTGGCGGTCGCTCCACCTATCAATGCTCCTACACGCTGCCCAATTCGATGCTCAGTCCGCTGCTCAGTCCCGATCAGGCGGCGGCCgctgcagccgccgccgccgttcaccagcagcagcaacaacaacagcaacatcagcagcagcagcagcaacatggtCCACTCAATGGctttggtggtggtggctccAATTCGCTGCCAGCGAGTCCCAGTCTCGGCGGGGCATCCATCAAGACGGAGCAATCGGAGCAGCTAAATCATCATACGTCACCATCAACGCGAGCCTCAAGCATTCCAGCCCTGCTGCAGGAAATCATGGATGTTGAACATCTCTGGCAATATACCGATGCGGAATTGGCACGCATTAATCAGCCGCTGTCCTCGTTTGCAACGGGTGGCTCATCGTCGAGCAGCACGGGCGGTTCAAGTTCCGCCGGACAGCATACGGGCAATGCACAACAGATGACCAATCCACTGCTGGCCAGTGCTGGTCTCGCATCCAACGGCGAGAACGCCAATCCCGATCTGATTGCACACCTCTGCAACGTGGCCGATCATCGCCTCTACAAGATCGTCAAATGGTGCAAGAGTTTGCCGCTCTTCAAGAACATCTCGATCGACGATCAGATCTGCCTGCTCATCAACTCGTGGTGCGAACTGTTGCTCTTCTCCTGCTGTTTTCGTTCGGTCGACACGCCCGGCGAGATCAAGATGTCGCAGGGCAGAAAGATTACGCTGGCACAGGCTAAAACCAATGGCTTGCAGGCGTGCATCGAGCGCATGTTGAATCTGACTGATCATTTGCGTCGCCTGCGCGTTGATCGCTACGAATATGTTGCCATGAAGGTAATCGTGCTGCTGCAGTCCGACACAACGGAACTGCACGAGGCAGTCAAGGTGCGCGAGTGCCAGGAGAAGGCGCTGCAGGGTTTGCAGGCCTACACGCTGGCCCATTACCCCGAGACGCCGTCCAAGTTTGGTGAGCTGCTCCTGCGCATACCCGATCTGCAGCGCACGTGTCAGCTGGGCAAGGAAATGCTGACGATCAAAACGCGCGACGGTGCAGACTTTAATTTGCTAATGGAACTGCTGCGCGGAGAACATTGA
Protein Sequence: MPNMSSIKTEQSVSPGASGSYQLPVNMSTATVTPASQQQQQQQQQQQQQQQHQRHNVSVTNIKCELDELATPTNGNLVPVIANYNNHNHNHNHNHSGSLRIPLGGNGDESDSDAELANIENLKVRRRASDKNGPRPMSWEGELSENETNGGAVGDEEELMETETVIKSEVSSSTSTSSSSSATTMASSQVNAMLQPIKTELENIAGEMQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQLQLQQQQQQLLPLKQQSYAPNNKLKLAPTQSDPINLKYEPTTTTTSSLLCDRSKSNSGGHLPLLPANPSPDSAIHSVYTHSSPSQSPLTSRHAPYTPSLSRNNSDASHSSCYSYSSEFSPTHSPIQARHAPLAGVAALFTGNANGGALHHHSVLYRPLNVDAAQEAQNLSMDAGGASLDASATLAASPAGISRQQLINSPCPICGDKISGFHYGIFSCESCKGFFKRTVQNRKNYVCVRGGPCQVSISTRKKCPACRFEKCLQKGMKLEAIREDRTRGGRSTYQCSYTLPNSMLSPLLSPDQAAAAAAAAAVHQQQQQQQQHQQQQQQHGPLNGFGGGGSNSLPASPSLGGASIKTEQSEQLNHHTSPSTRASSIPALLQEIMDVEHLWQYTDAELARINQPLSSFATGGSSSSSTGGSSSAGQHTGNAQQMTNPLLASAGLASNGENANPDLIAHLCNVADHRLYKIVKWCKSLPLFKNISIDDQICLLINSWCELLLFSCCFRSVDTPGEIKMSQGRKITLAQAKTNGLQACIERMLNLTDHLRRLRVDRYEYVAMKVIVLLQSDTTELHEAVKVRECQEKALQGLQAYTLAHYPETPSKFGELLLRIPDLQRTCQLGKEMLTIKTRDGADFNLLMELLRGEH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00575636;
90% Identity: iTF_00595983;
80% Identity: iTF_00498198;