Dcra008773.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila cracens
Gene Symbol
RREB1
Assembly
GCA_035042505.1
Location
JAWNLF010000633.1:3692041-3698750[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 13 0.036 2.4 8.8 0.8 1 21 260 280 260 282 0.93
2 13 0.00034 0.023 15.1 0.2 1 23 292 314 292 314 0.98
3 13 0.00025 0.017 15.5 7.2 1 23 320 342 320 342 0.98
4 13 0.89 60 4.4 1.5 2 20 573 591 573 593 0.93
5 13 0.017 1.1 9.8 0.2 1 23 737 759 737 759 0.97
6 13 4.6e-06 0.00031 21.0 1.2 1 23 769 791 769 791 0.99
7 13 0.00084 0.056 13.9 2.0 1 23 797 820 797 820 0.97
8 13 0.003 0.2 12.2 2.0 1 23 1079 1102 1079 1102 0.95
9 13 8.7e-05 0.0059 17.0 0.3 2 23 1484 1505 1483 1505 0.97
10 13 0.15 9.9 6.9 6.3 1 23 1511 1534 1511 1534 0.97
11 13 9.5 6.4e+02 1.2 3.4 1 23 1654 1677 1654 1677 0.78
12 13 0.0085 0.57 10.7 0.5 3 23 1737 1757 1735 1757 0.96
13 13 0.0014 0.091 13.3 4.8 1 23 1763 1785 1763 1785 0.99

Sequence Information

Coding Sequence
ATGCTcgccacacagcagcagcaacagcagcaaccacaacagcaacaatcgcacacagcagcagcaactgcagcagcagcagcaacacaagaGGATGCTCGGGACTTGGGATTAATGGAGACGCGACAACGTCGCGATTCGAGTACCTCAGAATCCTCGCTGGAGCATTTGGATTTGAGTCGCACGCCCAAaaagttgagcagcagcagcggcgcacCGCAGCCGACGTCAACGCCGCACGACACAGCAGTGACAGCGACGTCGCGCAAGCGAAAACTGCGACAgccacaccagcagcagcagcagcaacagttgccgctcTCCgatgaggagcagcagcagctgttggatTCGTCAGCGCAGCGACCGCGTCAAAAGCAGCGGCGCagcgttgttgctgccgctacCAGCGCCAGCATCGTTGTTGACTACAGCGCCAGCGGCGACGCCAGCTCGCTGCGTAAAAAGTTTCGACTGAAtcgcagcagcgccagcagcaatgCCGCCAACGGTGATTTATCCGAGTCTGGCTTTGTTGATGGTAGCGCCGTCAGTGGCTATCTgcttagcaacaacaacaataacaacaacaataacaataacaatatcaacaacaatatcagtagtagtagcagcagcagcgcagtcgctcagtcagcagcagcagtagcgtCGGCAGCACAGCATGCGTCAAGCGTTAGCAGCTCGGGCGGCTCCTCGCCACAGGGCCTCTCGAGCGCCGAGTCGGGCATCGGTGCTGGTGATGAGCACATGAAATATCTGTGCCCCATCTGCGAGGTCGTCTCGGCCACGCCCCACGAATTCACCAATCACATTCGCTGCCACAACTACGCCAACGGCGACACCGAGAACTTCACCTGCCGCATCTGCTCCAAGGTGCTCTCGTCGGCATCCTCTCTGGACCGCCATGTCCTGGTGCACACTGGAGAGCGTCCGTTCAACTGTCGCTATTGCCACTTGAACTTCACAACCAATGGGAACATGCACCGACACATGCGCACCCACAAGCAACATCAGGcctcgcagcagcagcagcaaccctcgcaacagcagcaatcaacccaacagcagcaacagccacaatcgcagtcgcagcaacagcaacagcgacgccAGCAACATGCGggcggagcagcagcaactggctCGGGATCGGGCTCGGGTTCAGCACAGTTGTTGACGACGCGAGCGGAGAGCTATGAGAGTGATGCCAGCTGCTCGACGGATGTGTCCAGTGAGCTGAACagtcacagcagcaacagcaatcaatccaaccacaacaacaacaacaatagccacaaaacgaacaacaataacaacaacagcaacaataataataataataacaatgagGATGAGCTCGAGCTGGAGGATGAGCAGCTAGTATTGAGCAGCAAACAGCGACGCCTCAAGGCAGccctaaacaacaacaatataattaGGGATGAGGAGCAGGAGAATCGTGTGGATGATGATTCGGATGTGGACAGCGTTGAGAGTGTGGCCCAGGTGATAACAAGCACACCGGATGTGGCCACGTTGCTCGCCTCGGGCGGCACCTCGCCCACCCACTCGCATTCCGAATTACATTCACCGCCCCTGCTGCAGAGCTGCCCCGCCTGCAATTCGGGTGAATTTGAATCTGTGCCAGCGTTGTGCGCCCATCTGGATGCCGAGCATGGGGACATACCGGCCAAGTGTCGCGAGTGTGAGGTGATCTATGCCACACATCGACAGCTGCAGGCGCACAGTTGTCGCGGATTGCCGCCGCTGCTTGGTGCGAGCTCGTCGCCACTGCACAAGCAGGAGGAGAGCGAactggaggagcagcagcagcagcacgaggAGGACCACgaacagcagcacaagcaggaGGAACAGGAGCACGCCGAGCAGCGCGAATGTGAAGATTTCTTCCAGCAGCTGTATTTGAAGAATAAATCGTCAGCAACGCTTCTTCCCTCCCCGATCAAACATGAGCCGGCGGATCAGCGACAGGATCTGGCCGATATTCAAAGCATACTCAATATGACCAGTTCCAGCTGCACATCCAGTTTCCTGCGCAATTTCGAGCAGTCGGTGAACACGCCCTGCTCCAGCCAATACAGCGTCGATGGACGCGATGGCGAGGAGGAGGCCCAGGATGCCTTCACCAATGAATTCCGCCGAATGAAACTGCGCGGTGAGTTCCCCTGTAAGCTGTGCAGCGCCGTCTTTCCCAATCTGCGGGCACTCAAGGGCCACAATCGCTACCATCTGTCGGAGGTGGGCGCCGCGGGTCCATTCCGTTGCAACATGTGTCCCTATGCCGTCTGCGACAAGTCGGCGCTCGTCCGGCACATGCGCACCCACAACGGTGATCGGCCATACGAGTGCGCCGTCTGCAACTATGCCTTCACCACCAAGGCGAACTGTGAGCGGCATTTGCGCAATCGTCATGGAAAGACTAGTCGCGAGGATGTGAAACGTGCGATTGTCTATCATCCGGCCGAGGATGCCAGCTGCGAGGAGAACAAATCCCGGACCGATGCCGATATGCTAACCGAGCTGAGCAGCTATCGCTGTCCCACACCCACGGAGCACAGCTCCTCGGCTAGCTCCTCGTCACAGCTGAAGCATATGTTGCTGGCGGAGCCGACGCCGGCCGTAAaggtaacagcagcagcaacagtggcagcaacaacatcgctGCCGCAACAACCGCTCAAGATTCAGGTGAAGAGCTTGGATCAGCTGGTGGATAAGCCACTGCCTGCACTCGATCTCAGCATGGATGCGCTCGACCTGAGCAAGAAGCCCGCACAGCTGCTGGCCGAGCAAAGGGAGCAAAGGGAGCAGCTCGAAAGACAcgaattgctgctgcagcagcaacaccaacagcagcagcagcagcagcaacaaatgtttgGGGCTGGCGATGCAGCTGCTCAGTacatgcagcagctgttgcgcaGCTTTATGCTCCAGCAGGCACCCGGTTTTCCTTTCTTTGGCTTTCTCACGCCGCCGCCACCTGCTacggcagcaactgcagcagacaagtcaatgccaacaaatccagcagcagcagccggcgcaacagcagcaacaattgccgcAATGCCACTGTCGCTGCCCGTGCCGCTGCCCGCTGGTGGTCCCGTCAAGATGGTCATCAAGAATGGCGTCCTGATGcccaagcagaagcagcgccGCTATCGCACCGAGCGTCCCTTTGCCTGCGAGCACTGCTCGGCCCGCTTCACGCTGCGCTCCAACATGGAGCGGCAtgtgaagcagcagcatccacagtTCTATGCGCTGCGCCAACGACACCGCAGCGGTCATCATGTGATGCGTGAACGGGCTGCGTCCTCGAGTGCTGTCCAAGCGGCAGCCGCTGctcaggcagcagcagcagctgccgcagcaatGAGTAAtctcagccagcagcaacagttgcagcagcagcaacagttgcagcattCACATCACGTCCATGCGCCAATTTCGGAGCAGGTGAAATATGCGATTTTGGCGCAGCAATTGAAGGCGCGCAAGGATACGGATTTGTTGCAACAGGCACTGGCACATGGTTCCAGCAGTGTTGTCGCCAATCCGCTGCTGCATTttagctacaacaacaacggcaacagcaacaagcagcagcagcaacaacagttgggCAACAACACTGGCCACTCTTTGGTGatggatgatgatgagccACCCAAGTTGATTATTGACGAGGATGACGAGGATGTGGAGGGAGaggacgatgaggatgaggaggaggaccAGGAATTTGATGTTGATGAGGAGGAACAGGAGGATGAAGAGATGGACTTGGACGatgagcatcagcagcagccgcacgaggaggatgacgatgacgttgatgatgatgatgatgatgctgcagcagcagcaacagaggcgtcgcagcaacaattgcagccaaCAAAGGACAAACTGCAATCCAAGCCAATTGAGGCGGCCAAAAAGGTAGCGGAAACCATATTGGAGCAGGCAATCAAAGAGCGCGAGGAGAAAGCCTCCGAGAAGCAGCCTCATACTCAAGCGGAGTCCCTGGGTGGAAATAAGCCGGCGACGCctacaacaatgaaaacaatgaTTGCACAAGCGGAATCGGTGGCCAAGTCCTTGAAGGAGGTGGCCAGTTCACCGTTTAAGGACGAATCTCAGGATCTGGTGCCGGTGGCCAAACTGGTGGACAATGCCACCAGCAATCAGGTGTCCTTCAACAGCTATTTCCGTCCCAGCGACGTCGCCAATCACATGGAGCAGAGCGACGAGGAGGGTCTTGTCGCCAGCGGCAGCGCCAGCGAGAGCAACAATTCCGGCACTGAGGAtgtgaccagcagcagcagcagctgcggcaacGATACCAAAAAGAAATCCGCCTACAGCCTGGCACCGAATCGTGTCAGCTGCCCATATTGCCAGCGCATGTTCCCCTGGAGCAGCTCGCTGCGTCGCCACATCCTGACGCACACCGGCCAGAAGCCGTTCAAGTGCTCCCACTGCCCGCTGCTCTTCACCACAAAGAGCAACTGCGATCGCCATCTGCTGCGCAAGCATGGCAACGTTGAGTCCGCCATGTCCGTCTATGTGCCCACCGAGGATGTCAGCGAACCGATTCCCGTGCCCAAGTCCGTCGAGGAGATTGAGCTCGAGGAGCAGCGACGTCGCCAGGCGGCCGAAGCCGAACAGGCCGAGCGGGAGCAGCGCGAGCGTCAAAAGGAGCGCGAACGCGAACTGGAAatggaacgggaacgggagcGTGAACAGCAACATTTGATACAACAGTATCGCCAACAAAtggccgctgctgcagcggctgctgttgcggttgccgCTGTCGCTGCACCAGCGCATCCAACACCACCACAGCCAGCCCAATCGCCACCGGGCCTGGAGGCCAGCAGTGATCTGCCCTACAAATGCCATCTGTGCGAATTCTCGTTTGGCGAGCGGCTGCAGTGCCTCGAGCACATCAAGCAGCTGCACGCTCACGACTTCGCCCTGCTCCTGGCCAAGGGGGCCATCGAAACGGATGCACAactgcagcatcaacagcagcaacagttgccaatGGCCGGTGGTGCTCCACATTCGGATGatgaggctgctgctgtcggcaCCAGATCGGGCAAATATCCCGACTATAGCAATCGTAAAGTGATTTGCGCATTTTGCGTGCGTCGCTTCTGGTCAACGGAGGATCTGCGCAGACATATGCGCACCCATTCCGGTGAGCGTCCGTTCCAGTGCGAGATCTGCTTGAGGAAGTTCACATTGAAGCACAGCATGCTGCGACACATGAAGAAGCACAGTGGACGCAGTCACAATGGTGGCGAACTCGATCATCAATCCGATTGCTCCGATGATGAGCAACTGTTGCCCTGCTCCCCACCCTCAACGCCAACGcccactaacaacaacaacaataacaacacttgccagaacaacaacaacaacaataacaacaacaatagcaatagtAACAGCAAGCAGGTGCTGCGCGAGCTGCTCGGCAAGGCGAACGAGTGGCGAGTGAGTCGCCTGGGTGAGCACAAGGAGAACATTGccgaggcaacaacaacaccctcagcagcaacagcagcagcggcagcaacagctgcagcagcagcagcggcggcagcagcagctgtggccaGTGGCGATCTAATTGGTAATCTGTTAGGGATCAGTGATCAGGGCATACTAAACAAGCTGCTCTCCTCACCGGACGAAGCTGCCAAGCTGCTAGGCGTGGAGAAGTAA
Protein Sequence
MLATQQQQQQQPQQQQSHTAAATAAAAATQEDARDLGLMETRQRRDSSTSESSLEHLDLSRTPKKLSSSSGAPQPTSTPHDTAVTATSRKRKLRQPHQQQQQQQLPLSDEEQQQLLDSSAQRPRQKQRRSVVAAATSASIVVDYSASGDASSLRKKFRLNRSSASSNAANGDLSESGFVDGSAVSGYLLSNNNNNNNNNNNNINNNISSSSSSSAVAQSAAAVASAAQHASSVSSSGGSSPQGLSSAESGIGAGDEHMKYLCPICEVVSATPHEFTNHIRCHNYANGDTENFTCRICSKVLSSASSLDRHVLVHTGERPFNCRYCHLNFTTNGNMHRHMRTHKQHQASQQQQQPSQQQQSTQQQQQPQSQSQQQQQRRQQHAGGAAATGSGSGSGSAQLLTTRAESYESDASCSTDVSSELNSHSSNSNQSNHNNNNNSHKTNNNNNNSNNNNNNNNEDELELEDEQLVLSSKQRRLKAALNNNNIIRDEEQENRVDDDSDVDSVESVAQVITSTPDVATLLASGGTSPTHSHSELHSPPLLQSCPACNSGEFESVPALCAHLDAEHGDIPAKCRECEVIYATHRQLQAHSCRGLPPLLGASSSPLHKQEESELEEQQQQHEEDHEQQHKQEEQEHAEQRECEDFFQQLYLKNKSSATLLPSPIKHEPADQRQDLADIQSILNMTSSSCTSSFLRNFEQSVNTPCSSQYSVDGRDGEEEAQDAFTNEFRRMKLRGEFPCKLCSAVFPNLRALKGHNRYHLSEVGAAGPFRCNMCPYAVCDKSALVRHMRTHNGDRPYECAVCNYAFTTKANCERHLRNRHGKTSREDVKRAIVYHPAEDASCEENKSRTDADMLTELSSYRCPTPTEHSSSASSSSQLKHMLLAEPTPAVKVTAAATVAATTSLPQQPLKIQVKSLDQLVDKPLPALDLSMDALDLSKKPAQLLAEQREQREQLERHELLLQQQHQQQQQQQQQMFGAGDAAAQYMQQLLRSFMLQQAPGFPFFGFLTPPPPATAATAADKSMPTNPAAAAGATAATIAAMPLSLPVPLPAGGPVKMVIKNGVLMPKQKQRRYRTERPFACEHCSARFTLRSNMERHVKQQHPQFYALRQRHRSGHHVMRERAASSSAVQAAAAAQAAAAAAAAMSNLSQQQQLQQQQQLQHSHHVHAPISEQVKYAILAQQLKARKDTDLLQQALAHGSSSVVANPLLHFSYNNNGNSNKQQQQQQLGNNTGHSLVMDDDEPPKLIIDEDDEDVEGEDDEDEEEDQEFDVDEEEQEDEEMDLDDEHQQQPHEEDDDDVDDDDDDAAAAATEASQQQLQPTKDKLQSKPIEAAKKVAETILEQAIKEREEKASEKQPHTQAESLGGNKPATPTTMKTMIAQAESVAKSLKEVASSPFKDESQDLVPVAKLVDNATSNQVSFNSYFRPSDVANHMEQSDEEGLVASGSASESNNSGTEDVTSSSSSCGNDTKKKSAYSLAPNRVSCPYCQRMFPWSSSLRRHILTHTGQKPFKCSHCPLLFTTKSNCDRHLLRKHGNVESAMSVYVPTEDVSEPIPVPKSVEEIELEEQRRRQAAEAEQAEREQRERQKERERELEMEREREREQQHLIQQYRQQMAAAAAAAVAVAAVAAPAHPTPPQPAQSPPGLEASSDLPYKCHLCEFSFGERLQCLEHIKQLHAHDFALLLAKGAIETDAQLQHQQQQQLPMAGGAPHSDDEAAAVGTRSGKYPDYSNRKVICAFCVRRFWSTEDLRRHMRTHSGERPFQCEICLRKFTLKHSMLRHMKKHSGRSHNGGELDHQSDCSDDEQLLPCSPPSTPTPTNNNNNNNTCQNNNNNNNNNNSNSNSKQVLRELLGKANEWRVSRLGEHKENIAEATTTPSAATAAAAATAAAAAAAAAAAVASGDLIGNLLGISDQGILNKLLSSPDEAAKLLGVEK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00535518;
90% Identity
iTF_00525357;
80% Identity
-