Basic Information

Insect: Drosophila cracens
Gene Symbol: Hr39
Assembly: GCA_035042505.1
Location: JAWNLF010000494.1:686608-689619[-]

Transcription Factor Domain

TF Family: SF-like
Domain: zf-C4|SF-like
PFAM: AnimalTFDB
TF Group: Zinc-Coordinating Group
Description: The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 3 0.44 3.9e+03 -3.1 10.1 31 204 41 208 33 212 0.44

2 3 2 1.8e+04 -10.0 25.1 43 147 195 319 174 357 0.36

3 3 3.6e-100 3.2e-96 323.2 13.6 1 408 492 881 492 881 0.86

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	3	0.44	3.9e+03	-3.1	10.1	31	204	41	208	33	212	0.44
2	3	2	1.8e+04	-10.0	25.1	43	147	195	319	174	357	0.36
3	3	3.6e-100	3.2e-96	323.2	13.6	1	408	492	881	492	881	0.86

Sequence Information

Coding Sequence: ATGCCAAATATGTCGAGCATTAAGACGGAGCAGAGTGTTTCACCCGGTGCCAGTGGCAGCTATCAGCTGCCCGAAAACATGTCGACGGCGACAGTGACGCCagcgttgcagcagcagcagcagcgtcacaATGTCTCCGTGACGAATATCAAATGTGAACTGGACGAGCTGGCGACGCCAACGAATGGCAACCTGGTGCCGGTCATAGCCAactataataatcataatcacaatcacaatcacaatcatAGCGGCAGCTTGCGCATTCCCCTCGGTGGCAATGGGGATGAGTCCGATTCGGATGCGGAGCTGGCGAACATTGAGAATCTAAAGGTGCGACGACGTGCGGCAGACAAGAATGGTCCGCGTCCCATGTCCTGGGAGGGTGAGCTGAGCGAGAACGAAACGAATGGCGGCGCCGTCGGTGACGAGGAGGAGCTCATGGAAACGGAAACGGTGATCAAGAGCGAggtgagcagcagcaccagcagcagcagcagtgccacaACGATGGCCAGCAGTCAAGTGAACGCCATGTTGCAGCCCATCAAAACCGAACTGGAGCACATAGCCGGGgagatgcaacaacagcaacagcagcagcaacaacagcagcagcagcaacaacagcagcaacaacagcagcagcagacactgcaacagcaacaacttcagctgcaacaacaacaattgctgccaCTGAAGCAACAGAGCTATGCACCGAACAACAAGCTAAAACTGGCGCCAACGCAAAGTGATCccatcaatttgaaatatgagccaacgacaacgacaacatcgtCGCTGCTCTGCGACAGGAGCAAGTCGAATAGTGGCGGCcatttgccactgctgcccgcCAATCCCAGTCCCGATTCTGCCATACATTCCGTCTATACGCACAGCAGTCCCTCCCAATCGCCGCTGACGTCCCGCCACGCCCCCTACACGCCCTCGCTGAGCAGAAACAACAGCGATGCGTCGCACAGCAGctgctacagctacagctccGAGTTCAGTCCCACCCACTCACCGATTCAGGCGCGTCATGCGCCACCCGCTGGCGTTGCTGCCTTGTTTGCCGGCAATGCAAATGGCGGTGCACTGCATCATCATAGTGTGCTCTATCGGCCACTCAATGTGGATGCCGCACAGGAGGCACAAAATCTGAGCATGGATGGTGCGGGTGGTGCAGCGCTGGATGCCAGTGCCACGTTGGCTGCCTCGCCGGCGGGCATCTCGCGTCAGCAGCTAATCAATTCGCCGTGTCCGATTTGTGGGGACAAAATCAGTGGCTTCCACTATGGCATCTTCTCTTGCGAGTCGTGCAAGGGCTTCTTCAAGCGCACCGTCCAGAATCGCAAgaactatgtgtgtgtgcgcggcGGTCCCTGCCAGGTGAGCATCTCGACGCGCAAAAAGTGCCCCGCTTGCCGTTTCGAGAAGTGTCTGCAGAAGGGCATGAAATTGGAGGCGATACGCGAGGATCGCACCCGAGGCGGTCGCTCCACCTATCAATGCTCCTACACGCTGCCCAATTCGATGCTCAGTCCGCTGCTCAGTCCGGATCAGGcggcagccgctgcagcagccgccgccgttgtcaatcagcagcagcagcatcagcaacaccaacagcagcgacttcaacagcatcagcagcagcaacaacagcagcaacagcagcagcagcaacacggTCCACTCAATGGCTTTGGTGGTGGCTCCAACTCGCTGCCAGCGAGTCCCAGTCTCGGCGGGGCATCCATCAAGACGGAGCAAACGGAGCAGCTTAATCATCACACGTCATCATCAGCGCGAGCCTCAAGCATTCCAGCCCTGTTGCAGGAAATCATGGATGTTGAACATCTCTGGCAATATACCGATGCGGAATTGGCACGCATTAATCAGCCGCTGTCCTCATTTGCAACTGGTGGCTCGTCGTCGAGCGGCACAGGCGGTTCAAGTTCCGCCGGACAGCATACGGGCAATGCACAACAGATGACCAATCCACTGCTGGCCAGTGCTGGTCTCTCGTCCAACGGTGAGAACGCCAATCCCGATCTGATCGCACACCTCTGCAACGTGGCCGATCATCGCCTCTACAAGATCGTCAAATGGTGCAAAAGTTTGCCGCTCTTCAAGAACATCTCGATTGACGATCAGATCTGCCTGCTCATTAACTCGTGGTGCGAACTGTTGCTCTTCTCCTGCTGTTTTCGTTCCGTCGATACGCCCGGCGAGATCAAGATGTCGCAGGGCAGAAAGATTACGCTGGCACAGGCTAAAACCAATGGCTTGCAGGCGTGCATTGAGCGCATGCTGAATCTGACGGATCATTTGCGTCGCCTGCGCGTTGATCGCTACGAATATGTTGCCATGAAGGTAATCGTGCTGCTGCAGTCCGACACAACGGAACTGCACGAGGCAGTCAAGGTGCGCGAGTGCCAGGAGAAGGCGCTGCAGGGTTTGCAGGCCTACACGCTGGCACATTATCCCGATACGCCGTCCAAGTTTGGTGAGCTGCTCCTGCGCATACCCGATCTGCAGCGCACGTGCcagCTGGGCAAGGAAATGCTGACGATCAAAACGCGCGATGGTGcagatttcaatttgctgatgGAACTGCTGCGCGGAGAACATTGA
Protein Sequence: MPNMSSIKTEQSVSPGASGSYQLPENMSTATVTPALQQQQQRHNVSVTNIKCELDELATPTNGNLVPVIANYNNHNHNHNHNHSGSLRIPLGGNGDESDSDAELANIENLKVRRRAADKNGPRPMSWEGELSENETNGGAVGDEEELMETETVIKSEVSSSTSSSSSATTMASSQVNAMLQPIKTELEHIAGEMQQQQQQQQQQQQQQQQQQQQQQQTLQQQQLQLQQQQLLPLKQQSYAPNNKLKLAPTQSDPINLKYEPTTTTTSSLLCDRSKSNSGGHLPLLPANPSPDSAIHSVYTHSSPSQSPLTSRHAPYTPSLSRNNSDASHSSCYSYSSEFSPTHSPIQARHAPPAGVAALFAGNANGGALHHHSVLYRPLNVDAAQEAQNLSMDGAGGAALDASATLAASPAGISRQQLINSPCPICGDKISGFHYGIFSCESCKGFFKRTVQNRKNYVCVRGGPCQVSISTRKKCPACRFEKCLQKGMKLEAIREDRTRGGRSTYQCSYTLPNSMLSPLLSPDQAAAAAAAAAVVNQQQQHQQHQQQRLQQHQQQQQQQQQQQQQHGPLNGFGGGSNSLPASPSLGGASIKTEQTEQLNHHTSSSARASSIPALLQEIMDVEHLWQYTDAELARINQPLSSFATGGSSSSGTGGSSSAGQHTGNAQQMTNPLLASAGLSSNGENANPDLIAHLCNVADHRLYKIVKWCKSLPLFKNISIDDQICLLINSWCELLLFSCCFRSVDTPGEIKMSQGRKITLAQAKTNGLQACIERMLNLTDHLRRLRVDRYEYVAMKVIVLLQSDTTELHEAVKVRECQEKALQGLQAYTLAHYPDTPSKFGELLLRIPDLQRTCQLGKEMLTIKTRDGADFNLLMELLRGEH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00575636;
90% Identity: iTF_00595983;
80% Identity: iTF_00497436;