Basic Information

Insect: Drosophila conformis
Gene Symbol: ush
Assembly: GCA_035041375.1
Location: JAWNLE010000373.1:808792-827056[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.054 3.5 8.3 0.0 1 20 202 221 202 223 0.89

2 9 0.00032 0.02 15.3 0.8 1 23 278 300 278 300 0.98

3 9 0.056 3.7 8.2 1.0 2 21 350 369 350 370 0.92

4 9 0.039 2.5 8.8 3.0 2 21 749 768 748 769 0.93

5 9 0.01 0.66 10.6 0.0 3 21 819 837 817 838 0.91

6 9 0.021 1.4 9.6 0.0 2 23 908 929 907 929 0.98

7 9 0.0043 0.28 11.8 1.3 1 23 935 957 935 957 0.99

8 9 0.0014 0.089 13.3 1.8 1 23 1024 1047 1024 1047 0.96

9 9 0.34 22 5.8 0.7 2 20 1157 1175 1156 1177 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.054	3.5	8.3	0.0	1	20	202	221	202	223	0.89
2	9	0.00032	0.02	15.3	0.8	1	23	278	300	278	300	0.98
3	9	0.056	3.7	8.2	1.0	2	21	350	369	350	370	0.92
4	9	0.039	2.5	8.8	3.0	2	21	749	768	748	769	0.93
5	9	0.01	0.66	10.6	0.0	3	21	819	837	817	838	0.91
6	9	0.021	1.4	9.6	0.0	2	23	908	929	907	929	0.98
7	9	0.0043	0.28	11.8	1.3	1	23	935	957	935	957	0.99
8	9	0.0014	0.089	13.3	1.8	1	23	1024	1047	1024	1047	0.96
9	9	0.34	22	5.8	0.7	2	20	1157	1175	1156	1177	0.91

Sequence Information

Coding Sequence: ATGATCAGCAgtcaaacaacagcagcaacaataaaagGTGATTGTTCCGATACCACAGAAGAGATGACCGTCGACAGCAGAGATTCCAAAGAATTGGCCGCACACGAGCTGAGCGAggagaagcaacagcaacaccagcagcaccaacaacaacagcaacagctcgaGGATCAGGCCGAAGACGAGCAGTTAGAGCAACAGTCGAACAACTCCTCCCTGCAACCCGTCGAGACTGACATGGACCAGGAACTGGAGGAGGCACAAGCGGCAGCCCAGGATTCCAGCGAACAGAAGTTGGAGGATAATCCGACAATGACAACGCCGCCGCGTAGCCCAACGCCCGAACTGGTGCCCAAGCTGGAGCGAGCTGATACGCCGCCCTCAGTTCCGGTCACGCCCAGCCCACCACCGCGTACGCCCACACCGCCGCCAATTGTGCTGCCCAAGCTGCGACTCAATGCGTTGCTTGCATCCGATCCGGCATTGAAGCCCGATGCCAAGGAGCTCAATATGCACGAGTCACGACTGCTGGGTCCACCGCCCAAGCCGGAGCAGCAACCGAGTCTGCAGCCGGATGTGGAGCCGCTGTTGAAACCGGCGCGATTTATGTGCCTGCCCTGCAGCATCGCTTTCAGTTCACCCTCAACACTGGAGGCGCATCAGGCCTACTACTGCTCCCATCGGAACAAGGATGCTGAGGAGGAGACAAACGCTGCCGGTGATAAGGTGACATCCAACAGCGGTGGCACCTCcaatgccaacagcagctCCAGCGGCTCAAGTGCCACCGGCTCCGAGCCACCCAACAAGGTGTCCCGCATTGGCAAACAGTATGCGTGCACCCAGTGCTCCTACAGTGCCGACAAGAAGGTCTCCCTCAATCGACACATGCGCATGCATCAAACATCCCCAGCGGCACCCAGCCTAAACAGCCTCTCCAGCTTGACAGCAAATGGTGTTGTTGCCgtggctgctgccgccgctgcggcagctgccgctgctgctggtgcgcAGCTCGAGGAGAGCTCTAGTCAACAAATCGATCGCTACTGCAGCGACTGTGATATCCGCTTCAACAACATCAAGACCTACCGCGCCCACAAGCAGCACTATTGCAGCTCCCGTCGCAGCGACGGACAACTGACGCCCAAGCCGGAGGCGGGTGGCATCACTGGAAGTGGAGTtggtggagctggagctggtggTGGGGGTGGAGCTGtatcagttgctgctgttgctgccggcaAGCACAGCCCACAGACGCGTAACAAGACGCCAACGCCAGCaatggttgctgctgccgccgccgcggctgcggctgctgctgcctcgctGCAGGTGGCACCACCGCAACCCTTCCTAGCGCTCCCCACCAATCCAATTATCATAGTGCCCTGCTCGCTAATACGTGCAGCCAGCTTGATACCTGGACCACTCACCACCTCTACGTCGGGCATTGTGAATCCGGAGTCCACATGCTTCACGCTCGACAATGGCGCTCTGAAGCCTCTAGCCACAGCTCTAAACATAAATACGCTAGGGGGCAGTGCCACGCCTACGCCTATGCCTAGCAGCAATCAGATACCGATTCCCGCTTTAGAGCCAGATCGTCCAACCCCTGTGAGCATTTCAAGCAACCTGGAAACGGAACCCAAGAAAAGTCCACCAGAACCCAAGCGCAAGGAAACAAGCGGCATACGTGAGACGACACCCCTGGATTTGTCGCTGAGGCGCTCGCCAATCTCTGCGCTATTGCAGCGCCAGCGTATCGCGCGCTCTGCCGCTGCGCTGCTGGACGCCGAGGATGCTGCAGGCAAGGATTCTCACTTGGAGAGCATCAGTGGCGGCAGCGTTACACCCGAGCAAATTGTTTGCGCTCCCTCGCTGCCCAGCAGCCCCTCGATGAGCCCCTCACCCAAGCGACGTGCTTTAAGTCCACGCAGCTCGGGAGCTGGGAGCGCTTCGTCGATGTCACCGCCAGCCCATCACATACTGGATAATTTGCCGCCGTTGCGCTCCATGCTGCCCTCCGACTTTAATCTCTCCGACTCGCTGCTGGCCAAAACGAATCCAGAGCTGGCCCTCAAactggcggcggcagcagcagctgctgtggcaggCAGTGGCTCGGCGGAGCTGGCTAAACTAGGATTTTCAGGAGGCGGTGCAGCAACCAGCAGTGGTGCTACTGCACCATCCTCTGCACAGAATGCACCACAGATCTATGTGAAGCAGGGCGTCTCCAAGTGTAAGGACTGCAATATTGTATTCTGCAAATATGAGAATTATTTGGCGCACAAGCAACATTATTGCTCGGCACGCAACCAGGAGGCGGGCCTGGATGGAGATGCCTCCAAGAGCGCTGTAACGCCTCCCAGTGGACTATCGTCAGTTGGTGGTAATGCTGGCGCCTCCTCTGCAGAAACCACTCCCGTTGCCTATCAGCAACTAATATGCGCCGCCTGTGGCATTAAGTACACCTCGCTGGATAATTTGCGTGCGCATCAGAATTACTACTGTTTGAAAGGAggcgctgcggctgctgcaacgCCAGCTgaggcagcaccagcaccacaacTGCCACTCGCCCATCCCAAGGAGAAGTGCCCAAAATGCAAGACTCATCATGAGCACGGACAGAATTGtccaccacctccaccaccgGCAACTCCACAACTGCCTGCTCCCTGCTCCACCTCTACCACGTCGAATAGTGTCAACAAGTGCCCCGTTTGTGGCGTAATTAGTCCCACAGCTGCCCTCGCCCGCAAGCACATGGAGATGCATGGAACGGTGAAGGCTTTTCGCTGCTCCATTTGCCAGTATAAAGGGAACACTCTCCGCGGGATGCGCACCCACATCCGCACACATTTCGATAAGAAGACCAGCGATGTGAATGAGGAGCACTACATGACATGCATCTTTGAGGAAGAtgctgcagcagtggcagctacAGTTGCTGCTCCAACTCAATCCTTGAATCTAGATCTGCCCGCtgtggcagcggcggcggcggcagcagcagcagcagcagctcaagaGCAACTGGAACAGCATCCGGCACAGCTCTTCAATTGCGATCATTGCAATTATGCCTCATCCTATAAGGGCAATGTGcTGCGTCACATGAAATTACTGCATCCACATGTGGCCATTAGTTCGCCCTCCATTTCACCCGAGTCGCGCGAACACGAAGCCAATCCTCATGCCCTACCCGAAATATCGCTGGTTAATGGGGAACGGGAGGCAGCATCTATGCCCATCTTCCACATTAAAACGGAGGCATTGGAGGCACCGGTGGCCACATTGAGTCTGGTGCATGAGAACAACAATTCACCCATTGGCACACCACTTACCCACATTAAAGCAGAGCCCATGGAACTTGGTGTAGATGTATCAGTACCGTCTCTACCCCCGCCGATGGCCAACTCCCCGCTTGGGCCGAGCGCAGCGGAGGCATTGAAAAAATACTGCTCCACCTGCGACATATCCTTCAACTATGTAAAAACATTTCTGGCGCACAAGCAATTCTACTGCAAGAGCAAACCACTCCGACCCGAGGCAAATGATAGCCCCAGTCCCACGGTGGGCGGTGGCGTCTCAATGCCGCTGCAGTCGCCCAgcgagctgctgttgctccagaAGAACAAGGAGAATCTGCAGGAGGCGGCCATTTGA
Protein Sequence: MISSQTTAATIKGDCSDTTEEMTVDSRDSKELAAHELSEEKQQQHQQHQQQQQQLEDQAEDEQLEQQSNNSSLQPVETDMDQELEEAQAAAQDSSEQKLEDNPTMTTPPRSPTPELVPKLERADTPPSVPVTPSPPPRTPTPPPIVLPKLRLNALLASDPALKPDAKELNMHESRLLGPPPKPEQQPSLQPDVEPLLKPARFMCLPCSIAFSSPSTLEAHQAYYCSHRNKDAEEETNAAGDKVTSNSGGTSNANSSSSGSSATGSEPPNKVSRIGKQYACTQCSYSADKKVSLNRHMRMHQTSPAAPSLNSLSSLTANGVVAVAAAAAAAAAAAAGAQLEESSSQQIDRYCSDCDIRFNNIKTYRAHKQHYCSSRRSDGQLTPKPEAGGITGSGVGGAGAGGGGGAVSVAAVAAGKHSPQTRNKTPTPAMVAAAAAAAAAAAASLQVAPPQPFLALPTNPIIIVPCSLIRAASLIPGPLTTSTSGIVNPESTCFTLDNGALKPLATALNINTLGGSATPTPMPSSNQIPIPALEPDRPTPVSISSNLETEPKKSPPEPKRKETSGIRETTPLDLSLRRSPISALLQRQRIARSAAALLDAEDAAGKDSHLESISGGSVTPEQIVCAPSLPSSPSMSPSPKRRALSPRSSGAGSASSMSPPAHHILDNLPPLRSMLPSDFNLSDSLLAKTNPELALKLAAAAAAAVAGSGSAELAKLGFSGGGAATSSGATAPSSAQNAPQIYVKQGVSKCKDCNIVFCKYENYLAHKQHYCSARNQEAGLDGDASKSAVTPPSGLSSVGGNAGASSAETTPVAYQQLICAACGIKYTSLDNLRAHQNYYCLKGGAAAAATPAEAAPAPQLPLAHPKEKCPKCKTHHEHGQNCPPPPPPATPQLPAPCSTSTTSNSVNKCPVCGVISPTAALARKHMEMHGTVKAFRCSICQYKGNTLRGMRTHIRTHFDKKTSDVNEEHYMTCIFEEDAAAVAATVAAPTQSLNLDLPAVAAAAAAAAAAAAQEQLEQHPAQLFNCDHCNYASSYKGNVLRHMKLLHPHVAISSPSISPESREHEANPHALPEISLVNGEREAASMPIFHIKTEALEAPVATLSLVHENNNSPIGTPLTHIKAEPMELGVDVSVPSLPPPMANSPLGPSAAEALKKYCSTCDISFNYVKTFLAHKQFYCKSKPLRPEANDSPSPTVGGGVSMPLQSPSELLLLQKNKENLQEAAI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00538480;
90% Identity: iTF_00570666;
80% Identity: -