Basic Information

Insect: Drosophila conformis
Gene Symbol: RREB1
Assembly: GCA_035041375.1
Location: JAWNLE010001151.1:5620050-5626683[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.039 2.5 8.8 0.8 1 21 266 286 266 288 0.93

2 12 0.00036 0.024 15.1 0.2 1 23 298 320 298 320 0.98

3 12 0.00027 0.018 15.5 7.2 1 23 326 348 326 348 0.98

4 12 0.95 62 4.4 1.5 2 20 578 596 578 598 0.93

5 12 0.018 1.2 9.8 0.2 1 23 742 764 742 764 0.97

6 12 1.3e-05 0.00087 19.7 0.7 1 23 774 796 774 796 0.99

7 12 0.0009 0.059 13.9 2.0 1 23 802 825 802 825 0.97

8 12 0.0032 0.21 12.2 2.0 1 23 1089 1112 1089 1112 0.95

9 12 9.4e-05 0.0061 17.0 0.3 2 23 1493 1514 1492 1514 0.97

10 12 0.16 10 6.8 6.3 1 23 1520 1543 1520 1543 0.97

11 12 0.0092 0.6 10.7 0.5 3 23 1746 1766 1744 1766 0.96

12 12 0.0015 0.094 13.2 4.8 1 23 1772 1794 1772 1794 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.039	2.5	8.8	0.8	1	21	266	286	266	288	0.93
2	12	0.00036	0.024	15.1	0.2	1	23	298	320	298	320	0.98
3	12	0.00027	0.018	15.5	7.2	1	23	326	348	326	348	0.98
4	12	0.95	62	4.4	1.5	2	20	578	596	578	598	0.93
5	12	0.018	1.2	9.8	0.2	1	23	742	764	742	764	0.97
6	12	1.3e-05	0.00087	19.7	0.7	1	23	774	796	774	796	0.99
7	12	0.0009	0.059	13.9	2.0	1	23	802	825	802	825	0.97
8	12	0.0032	0.21	12.2	2.0	1	23	1089	1112	1089	1112	0.95
9	12	9.4e-05	0.0061	17.0	0.3	2	23	1493	1514	1492	1514	0.97
10	12	0.16	10	6.8	6.3	1	23	1520	1543	1520	1543	0.97
11	12	0.0092	0.6	10.7	0.5	3	23	1746	1766	1744	1766	0.96
12	12	0.0015	0.094	13.2	4.8	1	23	1772	1794	1772	1794	0.99

Sequence Information

Coding Sequence: ATGCTcgccacacagcagcagcaacagcagcaaccacaacagcaacaatcgcacacagcagcagcaactgcagtagcagcagcagcagcagcaacacaagaGGATGCTCGGGATTTGGGATTAATGGAGACGCGACAACGTCGCGATTCGAGTACCTCAGAATCCTCGCTGGAGCATTTGGATTTGAGTCGCACGCCCAAaaagttgagcagcagcagcggcgcacCGCAGCCGACGTCGACGCCGCACGACACAGCAGTGACAGCGACGTCGCGCAAGCGAAAACTGCGACAgccacaccagcagcagcagcagcaacagttgccgctcTCCGAtgaggagcaacagcagcaacagcagcagcagctgttggaTTCGTCAACGCAGCGACCGCGTCACAAGCAGCGGCGCagcgctgttgctgccgctacCAGCGCCAGCATCGTTGTTGACTACAGCGCCAGCGGCGACGCCAGCTCGCTGCGCAAAAAGTTTCGACTGAAtcgcagcagcgccagcagcaatgCCGCCAACGGTGATTTATCCGAGTCTGGCTTTGTTGATGGCAGCGCCGTCAGTGGCTATCTgcttagcaacaacaacaataacaacaacaataacaatatcaacaacaatatcagtagtagtagcagcagcagcgcagtcgctcagtcagcagcagcagcagcgtcggcTGCGCAGCATGCGTCAAGCGTTAGCAGCTCGGGCGGCTCCTCGCCACAGGGCCTCTCGAGCGCCGAGTCGGGCATCGGTGCTGGGGATGAGCACATGAAATATCTGTGCCCCATCTGCGAGGTCGTCTCGGCCACGCCCCACGAATTCACCAATCACATTCGCTGCCACAACTACGCCAACGGCGACACCGAGAACTTCACCTGCCGCATCTGCTCCAAGGTGCTCTCGTCGGCATCCTCGCTGGACCGCCATGTCCTGGTGCACACTGGAGAGCGTCCGTTCAACTGTCGCTATTGCCACTTGAACTTCACAACCAATGGGAACATGCACCGACACATGCGCACCCACAAGCAACATCAGgcctcgcagcagcagcagcagcagccctcgcaacagcagcaatcaacccaacagcagcaacagccacaatcgcagtcgcagcaacagcaacagcgacgccAGCAACATGCGGGCGGAGCAGGCGCAACTGGCTCGGGATCGGGATCAGCACAGTTGTTGACGACGCGTGCGGAGAGCTATGAGAGTGATGCCAGCTGCTCGACGGATGTGTCCAGTGAGCTGAACagtcacagcagcaacagcaatcaatccaaccacaacaacaacaacaatagccacaaaacgaacaacaataacaacaacaacaacaataataataataataacaatgaggATGAGCTCGAGCTGGAGGATGAGCAGCTAGTATTGAGCAACAAACAGCGACGCCTCAAGGCAGccttaaacaacaacaatataattaGGGATGAGGAGCAGGAGAATCGTGTGGATGATGATTCGGATGTGGATAGCGTTGAGAGTGTGGCCCAGGTGATAACAAGCACACCGGATGTGGCCACGTTGCTCGCCTCGGGCGGCACCTCGCCCACCCACTCGCATTCGGAATTACATTCACCGCCCCTGCTGCAGAGCTGCCCCGCCTGCAATTCGGGTGAATTTGAATCTGTGCCAGCGCTGTGCGCCCATCTGGATGCCGAGCATGGGGACATACCGGCCAAGTGTCGCGAGTGTGAGGTGATCTATGCCACACATCGACAGCTGCAGGCGCACAGCTGTCGCGGATTGCCGCCGCTGCTTGGTGCGAGCTCATCGCCACTGCACAAGCAGGAGGAGAGCGAactggaggagcagcagcagcagcacgaggAGGATCACgaacagcagcacaagcaggaGGAACAGGAGCACGCCGAGCAGCGCGAATGTGAAGATTTCTTCCAGCAGCTGTATCTGAAGAATAAATCGTCAGCAACGCTTCTTCCCTCCCCGATCAAACATGAGCCGGCGGATCAGCGACAGGATCTGGCCGATATTCAAAGCATACTCAATATGACCAGTTCCAGCTGCACATCCAGTTTCCTGCGCAACTTCGAGCAGTCGGTGAACACGCCCTGCTCCAGCCAATACAGCGTCGATGGACGCGATGGCGAGGAGGAGGCCCAGGATGCCTTCACCAATGAATTCCGCCGAATGAAACTGCGTGGTGAGTTCCCCTGTAAGCTGTGCAGCGCCGTCTTTCCCAATCTGCGGGCACTCAAGGGCCACAATCGTTACCATCTGTCGGAGGTGGGCGCCGCGGGTCCATTCCGTTGCAACATGTGTCCCTATGCCGTCTGCGACAAGGCGGCGCTCGTCCGGCACATGCGCACCCACAACGGTGATCGGCCATACGAGTGCGCCGTCTGCAACTATGCCTTCACCACCAAGGCAAACTGTGAGCGGCATTTGCGCAATCGTCATGGAAAGACCAGTCGCGAGGATGTGAAACGTGCGATTGTCTATCATCCGGCCGAGGATGCCAGCTGCGAGGAGAACAAATCCCGGACCGATGCCGATATGCTAACCGAGCTGAGCGGCTATCGCTGTCCCACACCCACGGAGCACAGCTCCTCAGCTAGCTCCTCGTCACAGCTAAAGCATATGTTGCTGGCGGAGCCGACGCCGGCCGTaaaagtaacagcaacagcagcagcaacggtggcagcaacaacatcgctGCCGCAACAACCGCTCAAGATTCAGGTGAAGAGCTTGGATCAGCTGGTGGATAAGCCACTGCCTGCACTCGATCTCAGCATGGATGCGCTTGACCTGAGCAAGAAGCCCGCACAGCTGCTGGCCGAGCAAAGGGAGCAAAGGGAGCAGCTCGAAAGACAtgaattgctgctgcagcagcaacaccaacagcagcagcagcaacaacagcagcagcaacaaatgtttgGGGCTGGCGATGCAGCTGCTCAGTAtatgcaacagctgttgcGCAGCTTTATGCTCCAGCAGGCACCCGGTTTTCCTTTCTTTGGCTTTCTCacgccgccgccaccagcaacggcggcagcagcagcagacaagtcaatgccaacaaatccagcagcagcagccggcgcaacagcagcaacaattgctgcaatgCCACTGTCGCTGCCCGTGCCACTGCCCGCTGGTGGTCCCGTCAAGATGGTCATCAAGAATGGCGTCCTGATGcccaagcagaagcagcgccGCTATCGCACCGAGCGTCCTTTTGCCTGCGAGCACTGCTCGGCGCGCTTCACGCTGCGCTCCAACATGGAGCGGCAtgtgaagcagcagcatccacagtTCTATGCGCTGCGCCAGCGACACCGCAGCGGTCATCATGTGATGCGTGAACGGGCTGCGTCCTCGAGTGCTGTCCAAGCGGCAGCCGCTGctcaggcagcagcagcaactgccgcAGCAATGAGTAAtctcagccagcagcaacagttgcagcattcacattcacatcacGTCCATGCCCCAATTTCGGAGCAGGTGAAATATGCGATTTTGGCGCAGCAATTGAAGGCGCGCAAGGATACGGATTTGTTGCAACAGGCACTGGCACATGGTTCCAGCAGTGTTGTCGCCAATCCGCTGCTGCATTttagctacaacaacaacggcaacagcaacaaacagcaccagcaacaacagttgggCAACAACACTGGCAACTCTTTGGTGATGGACGATGATGAGCCACCCAAGTTGATTATTGACGAGGATGACGAGGATGTGGAGGGAgaggacgatgaggatgaggaggaggagcaggaatTTGATGTCGATGAGGATGAGCAGGAGGATGAAGAGATGGACGTGGACGatgagcatcagcagcagccgcacgaggaggatgacgatgacgatgatgatgatgttgatgatgatgctgcagcagcagcagcagcaaaagaggcgtcgcagcagcaattgcagccaaCAAAGGACAAACTGCAATCCAAGCCAATTGAGGCGGCCAAAAAGGTAGCGGAAACCATATTGGAGCAGGCAATCAAAGAGCGCGAGGAGAAAGCCTCCGAGAAGCAGCCGCATACTCAAGCGGAGTCCCTGAGCGGCAATAAGCCGGCGGCGCctacaacaatgaaaacaatgaTTGCACAAGCGGAATCGGTGGCCAAGTCCTTGAAGGAGGTGGCCAGTTCACCGTTTAAGGATGAATCTCAGGATCTGGTGCCGGTGGCCAAGCTGGTGGACAATGCCACCAGCAATCAGGTGTCCTTCAACAGCTATTTCCGTCCCAGCGACGTAGCCAATCACATGGAGCAGAGCGACGAGGAGGGTCTCGTCGCCAGCGGCAGCGCCAGCGAGAGCAACAATTCCGGCACCGAGGAtgtgaccagcagcagcagcagctgcggcaacGATACCAAAAAGAAATCCGCCTACAGCCTGGCACCGAATCGTGTCAGCTGCCCGTATTGCCAGCGCATGTTCCCCTGGAGCAGCTCGCTGCGTCGCCACATCCTGACGCACACCGGCCAGAAGCCGTTCAAGTGCTCCCACTGCCCGCTGCTCTTCACCACAAAGAGCAACTGCGATCGCCATCTGCTGCGCAAGCATGGCAACGTTGAGTCCGCCATGTCCGTCTATGTGCCCACCGAGGATGTCAGCGAACCGATTCCCGTGCCCAAGTCCGTCGAGGAGATTGAGCTCGAGGAGCAGCGACGTCGCCAGGCGGCCGAAGCCGAACAGGCCGAGCGGGAGCAGCGCGAGCGTCAAAAGGAGCGCGAACgtgaactggaactggaacgaGAACGGGAGCgggaacaacaacatttgatcCAACAGTATCGCCAACAAAtggccgctgctgcagcagctgctgttgccgttgccgctgTCGCTGCACCAGCGCATCCAACACCACCACAGCCAGCCCAATCGCCACCGGGCCTGGAGGCGAGCAGTGATCTGCCCTACAAATGCCATCTGTGCGAATTCTCGTTTGGCGAGCGGCTGCAGTGCCTCGAGCACATCAAGCAGCTGCACGCTCACGACTTCGCACTGCTCCTGGCCAAGGGGGCCATCGAAACGGATGCACAACtccagcatcaacagcagcaacagttgccaatGGCCGGTGGTGCTCCACATTCGGATGatgaggctgctgctgtcggcaCCAGATCGGGCAAGTATCCCGACTATAGCAATCGTAAAGTGATTTGCGCATTTTGCGTGCGTCGCTTCTGGTCAACGGAGGATCTCCGCCGACATATGCGCACCCATTCCGGTGAGCGTCCGTTCCAGTGCGAGATCTGCTTGAGGAAGTTCACATTGAAGCACAGCATGCTGCGACACATGAAGAAGCACAGTGGACGCAGTCACAATGGTGGCGAACTCGATCATCAATCCGATTGCTCCGATGATGAGCAACTGTTGCCCTGCTCCCCACCCTCAACGCCAACGcccactaacaacaacaacaacaacacttgccagaacaacaacaacaacaataacaacaacaatagcaatagtAACAGCAAGCAGGTGCTGCGCGAGCTGCTCGGCAAGGCGAACGAGTGGCGAGTGAGTCGCCTGGGTGAGCACAAGGAGAACATTGccgaggcaacaacaacaccctcagcagcaacagcagcagcggcagcaacagctgcagcagcagcagcggcggcagcagcagctgtggccaGTGGCGATCTAATTGGTAATCTGTTAGGGATCAGTGATCAGGGCATACTAAACAAGCTGCTCTCCTCACCGGACGAAGCTGCCAAGCTGCTAGGCGTGGAGAAGTAA
Protein Sequence: MLATQQQQQQQPQQQQSHTAAATAVAAAAAATQEDARDLGLMETRQRRDSSTSESSLEHLDLSRTPKKLSSSSGAPQPTSTPHDTAVTATSRKRKLRQPHQQQQQQQLPLSDEEQQQQQQQQLLDSSTQRPRHKQRRSAVAAATSASIVVDYSASGDASSLRKKFRLNRSSASSNAANGDLSESGFVDGSAVSGYLLSNNNNNNNNNNINNNISSSSSSSAVAQSAAAAASAAQHASSVSSSGGSSPQGLSSAESGIGAGDEHMKYLCPICEVVSATPHEFTNHIRCHNYANGDTENFTCRICSKVLSSASSLDRHVLVHTGERPFNCRYCHLNFTTNGNMHRHMRTHKQHQASQQQQQQPSQQQQSTQQQQQPQSQSQQQQQRRQQHAGGAGATGSGSGSAQLLTTRAESYESDASCSTDVSSELNSHSSNSNQSNHNNNNNSHKTNNNNNNNNNNNNNNNEDELELEDEQLVLSNKQRRLKAALNNNNIIRDEEQENRVDDDSDVDSVESVAQVITSTPDVATLLASGGTSPTHSHSELHSPPLLQSCPACNSGEFESVPALCAHLDAEHGDIPAKCRECEVIYATHRQLQAHSCRGLPPLLGASSSPLHKQEESELEEQQQQHEEDHEQQHKQEEQEHAEQRECEDFFQQLYLKNKSSATLLPSPIKHEPADQRQDLADIQSILNMTSSSCTSSFLRNFEQSVNTPCSSQYSVDGRDGEEEAQDAFTNEFRRMKLRGEFPCKLCSAVFPNLRALKGHNRYHLSEVGAAGPFRCNMCPYAVCDKAALVRHMRTHNGDRPYECAVCNYAFTTKANCERHLRNRHGKTSREDVKRAIVYHPAEDASCEENKSRTDADMLTELSGYRCPTPTEHSSSASSSSQLKHMLLAEPTPAVKVTATAAATVAATTSLPQQPLKIQVKSLDQLVDKPLPALDLSMDALDLSKKPAQLLAEQREQREQLERHELLLQQQHQQQQQQQQQQQQMFGAGDAAAQYMQQLLRSFMLQQAPGFPFFGFLTPPPPATAAAAADKSMPTNPAAAAGATAATIAAMPLSLPVPLPAGGPVKMVIKNGVLMPKQKQRRYRTERPFACEHCSARFTLRSNMERHVKQQHPQFYALRQRHRSGHHVMRERAASSSAVQAAAAAQAAAATAAAMSNLSQQQQLQHSHSHHVHAPISEQVKYAILAQQLKARKDTDLLQQALAHGSSSVVANPLLHFSYNNNGNSNKQHQQQQLGNNTGNSLVMDDDEPPKLIIDEDDEDVEGEDDEDEEEEQEFDVDEDEQEDEEMDVDDEHQQQPHEEDDDDDDDDVDDDAAAAAAAKEASQQQLQPTKDKLQSKPIEAAKKVAETILEQAIKEREEKASEKQPHTQAESLSGNKPAAPTTMKTMIAQAESVAKSLKEVASSPFKDESQDLVPVAKLVDNATSNQVSFNSYFRPSDVANHMEQSDEEGLVASGSASESNNSGTEDVTSSSSSCGNDTKKKSAYSLAPNRVSCPYCQRMFPWSSSLRRHILTHTGQKPFKCSHCPLLFTTKSNCDRHLLRKHGNVESAMSVYVPTEDVSEPIPVPKSVEEIELEEQRRRQAAEAEQAEREQRERQKERERELELEREREREQQHLIQQYRQQMAAAAAAAVAVAAVAAPAHPTPPQPAQSPPGLEASSDLPYKCHLCEFSFGERLQCLEHIKQLHAHDFALLLAKGAIETDAQLQHQQQQQLPMAGGAPHSDDEAAAVGTRSGKYPDYSNRKVICAFCVRRFWSTEDLRRHMRTHSGERPFQCEICLRKFTLKHSMLRHMKKHSGRSHNGGELDHQSDCSDDEQLLPCSPPSTPTPTNNNNNNTCQNNNNNNNNNNSNSNSKQVLRELLGKANEWRVSRLGEHKENIAEATTTPSAATAAAAATAAAAAAAAAAAVASGDLIGNLLGISDQGILNKLLSSPDEAAKLLGVEK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00535518;
90% Identity: iTF_00525357;
80% Identity: -