Dcon015413.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila conformis
Gene Symbol
Hr39
Assembly
GCA_035041375.1
Location
JAWNLE010001234.1:1101935-1104972[-]

Transcription Factor Domain

TF Family
SF-like
Domain
zf-C4|SF-like
PFAM
AnimalTFDB
TF Group
Zinc-Coordinating Group
Description
The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 3 0.68 6.3e+03 -3.8 12.1 25 206 40 211 30 216 0.44
2 3 2 1.8e+04 -11.1 27.6 47 148 198 325 175 362 0.34
3 3 4.7e-100 4.3e-96 322.9 13.3 1 408 497 886 497 886 0.85

Sequence Information

Coding Sequence
ATGCCAAATATGTCGAGCATTAAGACGGAGCAGAGTGTTTCACCCGGTGCCAGTGGCAGCTATCAGCTGCCCGAAAACATGTCGACGGCGACAGTGACGCCAgcgttgcagcagcatcagcagcagcgtcacaATGTCTCCGTGACGAATATCAAATGTGAACTGGACGAGCTGGCGACGCCAACGAATGGCAACCTGGTGCCGGTCATAGCCAactataataatcataatcacaatcacaatcacaatcataGCGGCAGCTTGCGCATTCCCCTCGGTGGCAATGGGGATGAGTCCGATTCGGATGCGGAGCTGGCGAACATTGAGAATCTAAAGGTGCGACGACGTGCGGCAGACAAGAATGGTCCGCGTCCCATGTCCTGGGAGGGTGAGCTGAGCGAGAATGAAACGAATGGCGGCGCCGTCGGCGACGAGGAGGAGCTCATGGAAACGGAAACGGTGATCAAGAGCGAggtgagcagcagcaccagcagcagcagcagtgccacaACGATGGCCAGCAGTCAAGTGAACGCCATGTTGCAGCCCATCAAAACCGAACTGGAGCACATAGCCGGGgagatgcaacaacagcaacagcagcagcagcaacagcaacaacagcagcagcagcagcaacaacagcagcaacaacagcagcagcagcaactgcaacagcaacaacttcaactgcaacaacaacaattgctgccacTGAAGCAACAGAGCTACGCACCGAACAACAAGCTAAAACTGGCGCCAACGCAAAGTGATCccatcaatttgaaatatgagccaacgacaacgacaacatcgtCGCTGCTCTGCGACAGGAGCAAGTCGAATAGTGGCGGCcatttgccactgctgcccgCCAATCCCAGTCCCGATTCTGCCATACATTCCGTCTATACGCACAGCAGCCCCTCCCAATCGCCGCTGACGTCCCGCCACGCCCCCTACACGCCCTCGCTGAGCAGAAACAACAGCGATGCGTcgcacagcagctgctacagctacagctccGAATTCAGTCCCACCCACTCACCGATTCAGGCGCGGCATGCGCCACCCGCTGGCGTTGCTGCCTTATTTGCCGGCAATGCAAATGGCGGTGCACTGCATCATCATAGTGTGCTGTATCGGCCACTCAATGTGGATGCCGCACAGGAGGCACAAAATCTGAGCATGGATGGTGCGGGTGGTGCAGCGTTGGATGCCAGTGCCACGTTGGCTGCCTCGCCGGCGGGCATCTCCCGTCAGCAGCTAATCAATTCGCCGTGTCCGATTTGTGGGGACAAGATCAGTGGCTTCCACTATGGCATCTTCTCGTGCGAGTCGTGCAAGGGCTTCTTCAAGCGCACCGTCCAGAATCGCAAgaactatgtgtgtgtgcgcggcGGTCCCTGCCAGGTGAGCATCTCGACGCGCAAAAAGTGTCCCGCCTGCCGTTTCGAGAAGTGTCTGCAGAAGGGCATGAAATTGGAGGCGATACGCGAGGATCGCACCCGAGGCGGTCGCTCCACCTATCAATGCTCCTACACGCTACCCAATTCGATGCTCAGTCCGCTGCTCAGTCCGGATCAGGCggcagccgccgcagccgccgccgccgttgtcaatcagcagcagcagcatcagcaacaccaacagcagcgacttcaacagcatcagcagcagcaacaacagcagcaacagcagcagcagcaacacggTCCACTCAATGGCTTTGGTGGTGGCTCCAACTCGCTGCCAGCGAGTCCCAGTCTCGGCGGCGCATCCATCAAGACGGAGCAAGCGGAGCAGCTTAATCATCATACGTCATCATCAGCGCGAGCCTCAAGCATTCCAGCCCTGTTGCAGGAAATCATGGATGTTGAACATCTCTGGCAATATACCGATGCGGAATTGGCACGCATTAATCAGCCGCTGTCCTCATTTGCAACTGGTGGCTCGTCGTCGAGCGGCACAGGCGGTTCAAGTTCCGCCGGACAGCATACGGGCAATGCACAACAGATGACCAATCCACTGCTGGCCAGTGCTGGTCTCTCATCCAACGGCGAGAACGCCAATCCCGATCTGATCGCACACCTCTGCAACGTGGCCGATCATCGCCTCTACAAGATCGTCAAATGGTGCAAAAGTTTGCCGCTCTTCAAGAACATCTCGATTGACGATCAGATCTGCCTGCTCATCAACTCGTGGTGCGAACTGTTGCTCTTCTCCTGCTGTTTTCGTTCCGTCGATACGCCCGGCGAGATCAAGATGTCGCAGGGCAGAAAGATTACGCTGGCACAGGCTAAAACCAATGGCTTGCAGGCGTGCATTGAGCGCATGCTGAATCTGACGGATCATTTGCGTCGCCTGCGCGTTGATCGCTACGAATATGTTGCCATGAAGGTAATCGTGCTGCTGCAGTCCGACACAACGGAACTGCACGAGGCAGTCAAGGTGCGCGAGTGCCAGGAGAAGGCGCTGCAGGGTTTGCAGGCCTACACGCTGGCCCATTATCCCGATACGCCGTCCAAATTTGGTGAGCTGCTCCTGCGCATACCCGATCTGCAGCGCACGTGCcagCTGGGCAAGGAAATGCTGACGATCAAAACGCGCGATGGTgcagatttcaatttgctgatgGAACTGCTGCGCGGAGAACATTGA
Protein Sequence
MPNMSSIKTEQSVSPGASGSYQLPENMSTATVTPALQQHQQQRHNVSVTNIKCELDELATPTNGNLVPVIANYNNHNHNHNHNHSGSLRIPLGGNGDESDSDAELANIENLKVRRRAADKNGPRPMSWEGELSENETNGGAVGDEEELMETETVIKSEVSSSTSSSSSATTMASSQVNAMLQPIKTELEHIAGEMQQQQQQQQQQQQQQQQQQQQQQQQQQQQLQQQQLQLQQQQLLPLKQQSYAPNNKLKLAPTQSDPINLKYEPTTTTTSSLLCDRSKSNSGGHLPLLPANPSPDSAIHSVYTHSSPSQSPLTSRHAPYTPSLSRNNSDASHSSCYSYSSEFSPTHSPIQARHAPPAGVAALFAGNANGGALHHHSVLYRPLNVDAAQEAQNLSMDGAGGAALDASATLAASPAGISRQQLINSPCPICGDKISGFHYGIFSCESCKGFFKRTVQNRKNYVCVRGGPCQVSISTRKKCPACRFEKCLQKGMKLEAIREDRTRGGRSTYQCSYTLPNSMLSPLLSPDQAAAAAAAAAVVNQQQQHQQHQQQRLQQHQQQQQQQQQQQQQHGPLNGFGGGSNSLPASPSLGGASIKTEQAEQLNHHTSSSARASSIPALLQEIMDVEHLWQYTDAELARINQPLSSFATGGSSSSGTGGSSSAGQHTGNAQQMTNPLLASAGLSSNGENANPDLIAHLCNVADHRLYKIVKWCKSLPLFKNISIDDQICLLINSWCELLLFSCCFRSVDTPGEIKMSQGRKITLAQAKTNGLQACIERMLNLTDHLRRLRVDRYEYVAMKVIVLLQSDTTELHEAVKVRECQEKALQGLQAYTLAHYPDTPSKFGELLLRIPDLQRTCQLGKEMLTIKTRDGADFNLLMELLRGEH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00575636;
90% Identity
iTF_00595983;
80% Identity
iTF_00496647;