Dcol001581.1
Basic Information
- Insect
- Drosophila colorata
- Gene Symbol
- -
- Assembly
- GCA_035041545.1
- Location
- JAWNLD010000016.1:6509281-6509802[+]
Transcription Factor Domain
- TF Family
- zf-LITAF-like
- Domain
- zf-LITAF-like domain
- PFAM
- PF10601
- TF Group
- Zinc-Coordinating Group
- Description
- Members of this family display a conserved zinc ribbon structure [3] with the motif C-XX-C- separated from the more C-terminal HX-C(P)X-C-X4-G-R motif by a variable region of usually 25-30 (hydrophobic) residues. Although it belongs to one of the zinc finger's fold groups (zinc ribbon), this particular domain was first identified in LPS-induced tumour necrosis alpha factor (LITAF) which is produced in mammalian cells after being challenged with lipopolysaccharide (LPS)[2]. The hydrophobic region probably inserts into the membrane rather than traversing it. Such an insertion brings together the N- and C-terminal C-XX-C motifs to form a compact Zn2+-binding structure [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 1 1.5e-25 1.2e-22 79.8 17.2 2 70 62 130 61 130 0.96
Sequence Information
- Coding Sequence
- ATGGAGCAACCGAAATCGAATCTTTATCCGCAAACGCCCGACGCGCCACCGCAATATGGCGACTTGGGCGGGCCGTCGATGATACCAACGGAGACGCTTACGTCGTCGCCTCCCGCGGCCGTAATTACCGTGCAGCAACCCAATGTTTATATGCAAGGTGGGGCACAAAACCATTTGGGCCGAATGCCAACAATGGCCGTCTGTCCCTCGTGCCAGGCCCGTCTGCTGACAACGGTTAAGCATGAGCCCAGCACCAAGACGCATCTCCTGGCGCTGGCCATTTGCCTGGTGGGcggcatctgctgctgctgcgttccCTACTGCGTGGACTCCTGCCAGAGCGCCATCCACACCTGCTCCAACTGTGGCGCCTTCGTGGGCGCCTATCAGAACTAA
- Protein Sequence
- MEQPKSNLYPQTPDAPPQYGDLGGPSMIPTETLTSSPPAAVITVQQPNVYMQGGAQNHLGRMPTMAVCPSCQARLLTTVKHEPSTKTHLLALAICLVGGICCCCVPYCVDSCQSAIHTCSNCGAFVGAYQN
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00561412; iTF_00538630; iTF_00547730; iTF_00567924; iTF_00508763; iTF_00530619; iTF_00542108; iTF_01326061; iTF_00598549; iTF_00531354; iTF_00491182; iTF_00551250; iTF_00534980; iTF_00563564; iTF_00617294; iTF_00506525; iTF_00475616; iTF_00526976;
- 90% Identity
- iTF_00530619;
- 80% Identity
- -