Basic Information

Insect: Drosophila cognata
Gene Symbol: prg
Assembly: GCA_035041535.1
Location: JAWNLC010000235.1:1951853-1953649[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.24 15 6.3 1.1 1 19 203 221 203 226 0.85

2 9 0.00023 0.015 15.8 0.1 1 23 232 255 232 255 0.97

3 9 7.6e-06 0.00049 20.4 0.4 1 23 261 283 261 283 0.97

4 9 1.1e-07 7.1e-06 26.2 4.3 1 23 289 311 289 311 0.98

5 9 6.1e-05 0.0039 17.6 0.8 1 23 317 339 317 339 0.98

6 9 5.9e-05 0.0038 17.6 0.3 1 23 345 367 345 367 0.98

7 9 3.3e-05 0.0021 18.4 0.5 1 23 441 463 441 463 0.96

8 9 2.1e-05 0.0013 19.1 0.2 1 23 468 491 468 491 0.91

9 9 0.044 2.8 8.6 0.6 1 23 495 517 495 517 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.24	15	6.3	1.1	1	19	203	221	203	226	0.85
2	9	0.00023	0.015	15.8	0.1	1	23	232	255	232	255	0.97
3	9	7.6e-06	0.00049	20.4	0.4	1	23	261	283	261	283	0.97
4	9	1.1e-07	7.1e-06	26.2	4.3	1	23	289	311	289	311	0.98
5	9	6.1e-05	0.0039	17.6	0.8	1	23	317	339	317	339	0.98
6	9	5.9e-05	0.0038	17.6	0.3	1	23	345	367	345	367	0.98
7	9	3.3e-05	0.0021	18.4	0.5	1	23	441	463	441	463	0.96
8	9	2.1e-05	0.0013	19.1	0.2	1	23	468	491	468	491	0.91
9	9	0.044	2.8	8.6	0.6	1	23	495	517	495	517	0.98

Sequence Information

Coding Sequence: ATGTCCGCAAGATCTGATCAAAATTTAACATCAGAATCAATGCGATGTCGCTTGTGCCACTCACGGATAAAATCGAACACAGATTCGCCGAATATTTACGAGGCGTCTGTTTACTTTGACAGAAgaacagaagaaaaaatcataattgcCGATGTTTGCCAGAGTGTTTATGGTGTGAAATATGAGCGCCATGAGTTACTGCCGGAGTTCATCTGTATGCTCTGCCTGGAGATATTGAGGGACTTCTACGAGGAACGTCAGTTCATTCAGCAGCATGAAttggagctgcagcagaacctaaagaaaataattgctGTGGATGCCAAGTATCGACCTGGCCTCAACGGCAATCCCGGCGAGTTTGAATTAGCGGAAGGCGAAGAACTTGTCGATGTGGATCCCGAGCAACTGTGCGAGACGAGTGATGACGAATTCCCCGGCTCCGAAGGTGAAGCTGAACTCGATGACGAGGTTGAGGAGGGAGGACCTGCACAAAATGAAGAAACCGAGATGCCCCTCGGCATGGATGCCGCCCAAATGGCGATGATGCGAGTGCATGAAACGGTCGACACCACCGTCCAATTCAATGCGCATCCAAAGAGCGCCTTCCTCTGCCAGTACTGCGATCTGGCCTTCACCCTACAGTCGGACTGCCAGCAACATGAGGTGGGCTCCCACGACTCTACGGCGCCGTACACTTGCAACTACTGTCAGGTGAGATTGACGACGCGTCCGGCTTTGATTGCGCACATCAGGGAGCTGCATGACGCCGAGCGTCCCTATGTGTGCGCACTGTGCAGGAAGGGATTCGTGAGACGTTCGGACTTAAAGAAGCACACAATTGTGCATACGGGCGTGCGTCCGTTCTCGTGCCACGTTTGCTCCAAGAGCTTCTCGCGCAACACCAATCTGACCAAGCATCTGCGCATCCACAGCAGCGTGAAGCCGTTCGTCTGCCAGCAGTGTCCGCGCTCTTTCCAGACATCGCTGGAGGTGCTGAAGCACATGCGCTCCCATGCCGAAGTGAAATTGTTTCGGTGCGGACGCTGTCCCGCCTCGTTCGCCCGCAAGGATAAGCTATTGATGCATCAGCAGGTTCATTTCAAGCGCGATATcgagcaaaagcaaactcaaAATCTGCGCATCAATATGATGAAGCCGGCAGAGCAGATGCAagtgcagctgccacagcaccCGTACGTGGAGGCAGATGCACCGGCCCAGCAGGCCTTACCAGCTATAACAACATATTCCAATCAGCAACAAACGCCTCCCGCGATGCAGCCAAAGGTGAAAGCAACGCCGAAGGTAACGCGCAATTTCCGCTGCGATGTATGCGATCGGGGCTTCCAACGAGAGCGGGATCTGCAGCGCCATCGGGCCCTGCACATGGACACACTATTCGCCTGCAAACTGTGCGGCCAGGGCTTTAATCGGCGCGAGCAACTGCAGCGCCACGAGCTGGAGGCTCATGGACCCAGCTATACATGTGCTATTTGCTGCATCACTTTCCTACAGCAAGCGGAGCTGGAGACGCATCTGAAAGTGCACGAGCTGCAGCACAGTGTGGCCAAAAGCAACCAGGAGGCGTTAATAGCTGCCGCCGCTGTAGTACCGCTAGCTCATTCCATGGGCGAGCACACCGGTGTCCCAGTGCCAGCCATCGTTCCGGAGCCCGTCCAGCTACCTAATGTTAGGCCTTCCGCAGCTGAAATGTCCTTCTATAGCATCATGATACCTACCATGAATCTAGGCTTCTACAGCGAGACGCGTCCCGAAGAGCGCAACGGAGTTTAA
Protein Sequence: MSARSDQNLTSESMRCRLCHSRIKSNTDSPNIYEASVYFDRRTEEKIIIADVCQSVYGVKYERHELLPEFICMLCLEILRDFYEERQFIQQHELELQQNLKKIIAVDAKYRPGLNGNPGEFELAEGEELVDVDPEQLCETSDDEFPGSEGEAELDDEVEEGGPAQNEETEMPLGMDAAQMAMMRVHETVDTTVQFNAHPKSAFLCQYCDLAFTLQSDCQQHEVGSHDSTAPYTCNYCQVRLTTRPALIAHIRELHDAERPYVCALCRKGFVRRSDLKKHTIVHTGVRPFSCHVCSKSFSRNTNLTKHLRIHSSVKPFVCQQCPRSFQTSLEVLKHMRSHAEVKLFRCGRCPASFARKDKLLMHQQVHFKRDIEQKQTQNLRINMMKPAEQMQVQLPQHPYVEADAPAQQALPAITTYSNQQQTPPAMQPKVKATPKVTRNFRCDVCDRGFQRERDLQRHRALHMDTLFACKLCGQGFNRREQLQRHELEAHGPSYTCAICCITFLQQAELETHLKVHELQHSVAKSNQEALIAAAAVVPLAHSMGEHTGVPVPAIVPEPVQLPNVRPSAAEMSFYSIMIPTMNLGFYSETRPEERNGV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00511438;
90% Identity: iTF_00610063;
80% Identity: -