Dcog000049.1
Basic Information
- Insect
- Drosophila cognata
- Gene Symbol
- Hr39
- Assembly
- GCA_035041535.1
- Location
- JAWNLC010000013.1:478599-481649[-]
Transcription Factor Domain
- TF Family
- SF-like
- Domain
- zf-C4|SF-like
- PFAM
- AnimalTFDB
- TF Group
- Zinc-Coordinating Group
- Description
- The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 3 0.24 2.1e+03 -2.2 13.8 21 205 39 217 24 222 0.45 2 3 2 1.8e+04 -10.4 26.9 27 150 210 335 196 372 0.30 3 3 4.1e-100 3.7e-96 323.0 12.2 1 408 505 896 505 896 0.85
Sequence Information
- Coding Sequence
- ATGCCAAATATGTCGAGCATTAAGACGGAGCAGAGTGTTTCACCCGGTGCCAGTGGCAGCTATCAGCTGCCCGAAAACATGTCGACGGCGACAGTGACGCCagcgttgcagcagcagcagcagcatcatcagcagcagcagcgtcacaATGTCTCCGTGACGAATATCAAATGTGAACTGGACGAGCTGGCGACGCCAACGAATGGCAACCTGGTGCCGGTCATAGCCAactataataatcataatcacaatcacaatcacaatcacaatcataGCGGCAGCTTGCGCATTCCCCTCGGTGGCAATGGGGATGAGTCCGATTCGGATGCGGAGCTGGCGACCATTGAGAATCTGAAGGTGCGACGACGTGCGGCAGACAAGAATGGTCCGCGTCCCATGTCTTGGGAGGGTGAGCTGAGCGAGAACGAAACGAATGGCGGCGCCGTCGGTGACGAGGAGGAGCTCATGGAAACGGAAACGGTGATCAAGAGCGAggtgagcagcagcaccagcagcagcagcagtgccacaACGATGGCCAGCAGTCAAGTGAACGCCATGTTGCAGCCCATCAAAACCGAACTGGAGCACATAGCCGGGgagatgcaacaacagcaacagcagcagcaacaacagcaacaacaacagcagcagcaacaacagcagcaacaacagcagcagcagcagcagcaactgcaacagcaacaacttcagctgcaacaacaacaattgctgccaCTGAAGCAACAGAGCTATGCACCGAACAACAAGCTAAAACTTGCGCCAACGCAAAGTGATCccatcaatttgaaatatgagccaacgacaacgacaacatcgtCGCTGCTCTGCGACAGGAGCAAGTCGAATAGTGGCGGCcatttgccactgctgcccGCCAATCCCAGTCCCGATTCTGCCATACATTCCGTCTATACGCACAGCAGCCCCTCCCAATCGCCGCTGACGTCCCGCCACGCCCCCTACACGCCCTCGCTGAGCAGAAACAACAGCGATGCGTCGCACAGCAGctgctacagctacagctccGAATTCAGTCCCACCCACTCACCGATACAGGCGCGTCATGCGCCACCCGCTGGCGTTGCTGCCTTGTTTGCCGGCAATGCAAATGGCGGTGCACTGCATCATCATAGTGTGCTCTATCGGCCACTCAATGTGGATGCCGCACAGGAGGCACAAAATCTGAGCATGGATGGTGCGGGCGGTGCATCGCTGGATGCCAGTGCCACGTTGGCTGCCTCGCCGGCGGGCATCTCGCGTCAGCAGCTAATCAATTCGCCGTGTCCGATTTGTGGGGACAAGATCAGTGGCTTCCACTATGGCATCTTCTCGTGCGAGTCGTGCAAGGGCTTCTTCAAGCGCACCGTCCAGAATCGCAAgaactatgtgtgtgtgcgcggcGGTCCCTGCCAGGTGAGCATCTCGACGCGCAAAAAGTGTCCCGCCTGCCGTTTCGAGAAGTGTCTGCAGAAGGGCATGAAATTGGAGGCGATACGCGAGGATCGCACCCGAGGCGGTCGCTCCACTTATCAATGCTCCTACACGCTGCCCAATTCGATGCTCAGTCCGCTGCTCAGTCCGGATCAGGCGgcagccgctgcagccgccgccgccgttgtcaatcagcagcagcaacatcagcaacaccaacagcagcgacttcaacagcatcagcagcagcaacaacagcagcaacagcagcagcagcaacacggTCCACTCAATGGctttggtggtggtggtggctccAACTCGCTGCCAGCGAGTCCCAGTCTCGGCGGGGCATCCATCAAGACGGAGCAAGCGGAGCAGCTTAATCATCATTCGTCATCATCAGCGCGAGCCTCAAGCATTCCAGCCCTGTTGCAGGAAATCATGGATGTTGAACATCTCTGGCAATATACCGATGCGGAATTGGCACGCATTAATCAGCCGCTGTCCTCATTTGCAACTGGTGGCTCAGCGTCGAGCGGCACAGGCGGTTCTAGTTCCGCCGGACAGCATACGGGCAATGCACAACAGATGACCAATCCACTGCTGGCCAGTGCTGGTCTCTCATCCAACGGCGAGAACGCCAATCCCGATCTGATCGCACACCTCTGCAACGTGGCCGATCATCGCCTCTACAAGATCGTCAAATGGTGCAAGAGTTTGCCGCTCTTCAAGAATATCTCGATTGACGATCAGATCTGCCTGCTCATCAACTCGTGGTGCGAACTGTTGCTCTTCTCCTGCTGTTTTCGTTCCGTCGATACGCCCGGCGAGATCAAGATGTCACAGGGCAGAAAGATAACGCTGGCACAGGCTAAAACCAATGGCTTGCAGGCGTGCATTGAGCGCATGCTGAATCTGACGGATCATTTGCGTCGCCTGCGCGTTGATCGCTACGAATATGTTGCCATGAAGGTAATCGTGCTGCTGCAGTCCGACACAACGGAACTGCACGAGGCAGTCAAGGTGCGCGAGTGCCAGGAGAAGGCGCTGCAGGGCTTGCAGGCCTACACGCTGGCCCATTATCCCGATACGCCGTCCAAGTTTGGTGAGCTGCTCCTGCGCATACCCGATCTGCAGCGCACGTGTcagCTGGGCAAGGAAATGCTGACGATCAAAACGCGCGATGGTGcagattttaatttgctgaTGGAACTGCTGCGCGGAGAACATTGA
- Protein Sequence
- MPNMSSIKTEQSVSPGASGSYQLPENMSTATVTPALQQQQQHHQQQQRHNVSVTNIKCELDELATPTNGNLVPVIANYNNHNHNHNHNHNHSGSLRIPLGGNGDESDSDAELATIENLKVRRRAADKNGPRPMSWEGELSENETNGGAVGDEEELMETETVIKSEVSSSTSSSSSATTMASSQVNAMLQPIKTELEHIAGEMQQQQQQQQQQQQQQQQQQQQQQQQQQQQQLQQQQLQLQQQQLLPLKQQSYAPNNKLKLAPTQSDPINLKYEPTTTTTSSLLCDRSKSNSGGHLPLLPANPSPDSAIHSVYTHSSPSQSPLTSRHAPYTPSLSRNNSDASHSSCYSYSSEFSPTHSPIQARHAPPAGVAALFAGNANGGALHHHSVLYRPLNVDAAQEAQNLSMDGAGGASLDASATLAASPAGISRQQLINSPCPICGDKISGFHYGIFSCESCKGFFKRTVQNRKNYVCVRGGPCQVSISTRKKCPACRFEKCLQKGMKLEAIREDRTRGGRSTYQCSYTLPNSMLSPLLSPDQAAAAAAAAAVVNQQQQHQQHQQQRLQQHQQQQQQQQQQQQQHGPLNGFGGGGGSNSLPASPSLGGASIKTEQAEQLNHHSSSSARASSIPALLQEIMDVEHLWQYTDAELARINQPLSSFATGGSASSGTGGSSSAGQHTGNAQQMTNPLLASAGLSSNGENANPDLIAHLCNVADHRLYKIVKWCKSLPLFKNISIDDQICLLINSWCELLLFSCCFRSVDTPGEIKMSQGRKITLAQAKTNGLQACIERMLNLTDHLRRLRVDRYEYVAMKVIVLLQSDTTELHEAVKVRECQEKALQGLQAYTLAHYPDTPSKFGELLLRIPDLQRTCQLGKEMLTIKTRDGADFNLLMELLRGEH
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00575636;
- 90% Identity
- iTF_00595983;
- 80% Identity
- iTF_00495159;