Dcar001482.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila carrolli
Gene Symbol
Slc7a11
Assembly
GCA_018152295.1
Location
JAECXJ010000159.1:3369791-3371728[+]

Transcription Factor Domain

TF Family
BTB
Domain
zf-C2H2|ZBTB
PFAM
PF00651
TF Group
Zinc-Coordinating Group
Description
The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 1 9.6e-11 2.5e-08 34.0 1.7 1 101 25 128 25 133 0.92

Sequence Information

Coding Sequence
ATGCTCCATTCTCAGGCGATGCAATCCGTACCCACTCTACACCAGCCGCTGCATTCCAAGGTGTCGAATTACCTGAACAATCAGCGGAGAACAGGACAGTTTTGTGACCTGCTCCTGGAACTGGATTCGGATGACTCCCTTAGCTTGAGTGTCCATTTCTGCGTGCTGGCCGCCCAGAGCCAGTTGATAAACACCAACCAAAAGCAGCAGCAGTTTTCCATCCACAATCCCCTGAAGATCACCATCCGGAATTTCAGCTGCACTCAGTGCCTGCACACAATTGTAGACTTCTTCTACGAAGACATAGTCTCCGTGTCCAAGGAGCACGAGCTCCACTTCCGAGAGTTGGCGCAAATCTTGGCTGTCACCGAACTGCTAAATCTCTACCAGTTGCAGCCTGTGGGAGAGGTGAAGGAAACTTTAGAGATTACGGCTCCTGGAGAGTTGGAACAAAACCTGGAGCCAGCAAGAAAAGTAGATGATTTGTTTGAAAATCGACAAAGTTACTTTAAACTAAAGAACCCAAGGGCCGTGAAATCCAGCAGTAAGGTGAACTACTGCATTGGCTGCGACTACAAATGCTACCAGGTGCAGAAGATGATCGAGCACATGGGAAGTTGTGAGCCCTCGCATCTGACCTGTTCCCTGTGCGAAGTGGGATTCCTGGACTGGCGGGAGTACGACACACATCTTCGCAGGCACTCAAATGACCTTCGCAAACCCTTCTTCTGCCTGCAATGCGGCATTCGCTTCACCACTAGAGCTGCCCTGCTCGTCCATCAACCCAAGCACTCCACGGAAACGCCACACATCTGTCCCCATTGCGGCAAAGGTTTCAAGTGGAAGCAGGGACTGAGCAACCACATCCTGGTGCACAATCCCGAGAAGCAGATGCTATGCGACGTCTGCGGATACAGCACCACCCACATGAAGGCCTTAAAATCCCACAAACTGCTCCACACCGGGGAATTCTTCGCTTGCACAGTTTCGGGCTGTAAGCATCGAGCCAATCGCAAGGAGAACCTCAAGCTACACATCGAAACCCACAAGCAGGGACGGGATTTCATCTGCGAGATCTGCGGCTGCAAGTTCAGCCAGAGCAAGAACCTCAAGCGACACGCCCTGAAGCACACGGAGAATGGTCCGAATCGATACAAGTGCCAGCTGTGTGGGTTTAGTAGCCATCGTTCCGACAAGATGAAAGAGCACGTGCAGCGAGTGCACACGGAAAAGGCGGTGCAATTGGAGCTCTCTGAGACGGTGGACAGTTCCTTTCCCGACGACTTTGATCTGCCTGTAATCGAGACTTTATTTTGGAAATTCCACTTTTCAAGAATAATTAAAATTAATCTTACTTTTGATTATGATCAAATCAATCTTGCGCTGCCCATTATCTTCATGGTGAGCTGCGTGACGTTGGTCCTGCTCCCGAATATGGAGGAGCCAGGTAATCTCTTGATTGGTATCGGTATCACCCTGGCCGGCATTCCATTTTACTATGGCTTCATCGCCTGGGAAAAAAAGCCCAAGTGCTACGGGCGATTGTCAAACTCCGTTGTAGAGATTTGTCGGGCCATCTTTAACACCACCGTAATCGAATCGAACGAAAAGATAAACTAG
Protein Sequence
MLHSQAMQSVPTLHQPLHSKVSNYLNNQRRTGQFCDLLLELDSDDSLSLSVHFCVLAAQSQLINTNQKQQQFSIHNPLKITIRNFSCTQCLHTIVDFFYEDIVSVSKEHELHFRELAQILAVTELLNLYQLQPVGEVKETLEITAPGELEQNLEPARKVDDLFENRQSYFKLKNPRAVKSSSKVNYCIGCDYKCYQVQKMIEHMGSCEPSHLTCSLCEVGFLDWREYDTHLRRHSNDLRKPFFCLQCGIRFTTRAALLVHQPKHSTETPHICPHCGKGFKWKQGLSNHILVHNPEKQMLCDVCGYSTTHMKALKSHKLLHTGEFFACTVSGCKHRANRKENLKLHIETHKQGRDFICEICGCKFSQSKNLKRHALKHTENGPNRYKCQLCGFSSHRSDKMKEHVQRVHTEKAVQLELSETVDSSFPDDFDLPVIETLFWKFHFSRIIKINLTFDYDQINLALPIIFMVSCVTLVLLPNMEEPGNLLIGIGITLAGIPFYYGFIAWEKKPKCYGRLSNSVVEICRAIFNTTVIESNEKIN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00512290; iTF_00473923; iTF_00588259; iTF_00604963; iTF_00575173; iTF_00494502; iTF_00578662; iTF_00507719; iTF_00484552; iTF_00578856; iTF_00605162; iTF_00504971; iTF_00515819; iTF_00581835; iTF_00481164; iTF_00484716; iTF_00529676; iTF_00548364; iTF_00591980; iTF_00505517; iTF_00471758; iTF_00480974; iTF_00539950; iTF_00536367; iTF_00494672; iTF_00536178; iTF_00588434; iTF_00529843; iTF_00537075; iTF_00580883; iTF_00486676; iTF_00505684; iTF_00602932; iTF_00581109; iTF_00605877; iTF_00487414; iTF_00512118; iTF_00548182; iTF_00494679; iTF_00539768; iTF_00581656; iTF_00602712; iTF_00487577; iTF_00507897; iTF_00517850; iTF_00536890; iTF_00515707; iTF_00504797; iTF_00471966; iTF_00486846; iTF_00591806; iTF_00605694; iTF_00518047; iTF_00608018; iTF_00619256; iTF_00619434; iTF_00565658; iTF_00565490; iTF_00477441; iTF_00504097; iTF_00488291; iTF_00539235; iTF_00615012; iTF_00476037; iTF_00504264; iTF_00477609; iTF_00615182; iTF_00481647; iTF_00476209; iTF_00550356; iTF_00580084; iTF_00546072; iTF_00566200; iTF_00580249; iTF_00481820; iTF_00615676; iTF_00566365; iTF_00615773; iTF_00488127; iTF_00539071; iTF_00550527; iTF_00546240; iTF_00541185; iTF_00492513; iTF_00609281; iTF_00488930; iTF_00533346; iTF_00594818; iTF_00569795; iTF_00569955; iTF_00613603; iTF_00524676; iTF_00617764; iTF_00491621; iTF_00613061; iTF_00478279; iTF_00485415; iTF_00488775; iTF_00490343; iTF_00617863; iTF_00489640; iTF_00606600; iTF_00485259; iTF_00524523; iTF_00606444; iTF_00478126; iTF_00490190; iTF_00590350; iTF_00483215; iTF_00489487; iTF_00561874; iTF_00590483; iTF_00483093; iTF_00594101; iTF_00609429; iTF_00531896; iTF_00533208; iTF_00480409; iTF_00525977; iTF_00562009; iTF_00480282; iTF_00492346; iTF_00526138; iTF_00613754; iTF_00531771; iTF_00541340; iTF_00593948; iTF_00612924; iTF_00491773; iTF_00594656; iTF_00572153; iTF_00572007; iTF_00594843; iTF_00594657; iTF_00474630; iTF_00474786; iTF_00611468; iTF_00474114; iTF_00574949; iTF_00611636; iTF_00603640; iTF_00603482;
90% Identity
iTF_00619256;
80% Identity
iTF_00494679;