Dbuz011870.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila buzzatii
Gene Symbol
-
Assembly
GCA_035045845.1
Location
JAWNOS010000488.1:258378-263011[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 26 0.001 0.08 13.7 1.7 1 23 220 242 220 242 0.97
2 26 0.021 1.6 9.5 2.9 1 23 248 270 248 270 0.97
3 26 0.08 6.3 7.7 1.1 2 20 302 320 302 323 0.94
4 26 0.00043 0.033 14.8 3.7 1 23 398 421 398 421 0.94
5 26 1.5 1.2e+02 3.6 0.9 2 22 432 452 431 452 0.95
6 26 1.8 1.4e+02 3.5 0.2 1 20 461 480 461 482 0.89
7 26 0.44 35 5.4 1.3 2 23 496 517 495 517 0.97
8 26 1.7 1.4e+02 3.5 4.5 1 23 597 620 597 620 0.94
9 26 0.00073 0.057 14.1 0.1 1 22 629 650 629 650 0.96
10 26 0.21 16 6.4 3.1 1 23 659 682 659 682 0.96
11 26 0.0011 0.085 13.6 0.2 2 23 713 734 712 734 0.97
12 26 1.4e-05 0.0011 19.5 5.7 1 23 742 764 742 764 0.99
13 26 0.023 1.8 9.4 1.2 1 23 912 935 912 935 0.92
14 26 0.0096 0.75 10.6 0.2 2 22 943 963 943 963 0.95
15 26 0.28 22 6.0 0.6 1 23 972 995 972 995 0.93
16 26 1.1e-05 0.00087 19.8 1.9 1 23 1020 1042 1020 1042 0.97
17 26 0.00014 0.011 16.4 0.9 1 23 1049 1071 1049 1071 0.98
18 26 0.013 0.98 10.2 0.0 2 21 1098 1117 1097 1118 0.94
19 26 0.013 1 10.1 4.3 1 23 1163 1186 1163 1186 0.96
20 26 0.0073 0.57 11.0 0.9 1 23 1223 1246 1223 1246 0.95
21 26 0.0045 0.35 11.6 3.2 1 23 1274 1297 1274 1297 0.98
22 26 1.4e-05 0.0011 19.5 0.1 2 23 1325 1346 1324 1346 0.95
23 26 4.7e-05 0.0037 17.8 2.9 1 23 1352 1374 1352 1374 0.99
24 26 2.5e-06 0.0002 21.8 2.3 1 23 1380 1402 1380 1402 0.98
25 26 5.9e-08 4.6e-06 27.0 2.4 1 23 1408 1430 1408 1430 0.99
26 26 0.00071 0.056 14.1 0.3 1 21 1436 1456 1436 1460 0.91

Sequence Information

Coding Sequence
ATGTTGCCAACAGATATTTGCCGTACATGCACACTGCATGATGACAGTTTGTTTCCGCTTGCGACCCGTGCTGATAAGTATGCGAATAAAAGTTTAAATGACATGTTACTCGAATTGACCCAAATTGATCCCCTGCAGGAGCATACGGATGATAGTTTGCCACAGAACTTGTGTATGTGCTGCTTACACAAATTGGAGGCTGCCTATGCGTTTGTATTGCAGGCGCGCCAAGCTCAAGAGCAATTTTTGCAACAGCTGCACAAAGGCTTGCAGACACAATGCTTGGATGAGATGCCCATAGACATTAACTTACAGCATATAAAAACCGAAACGGTCGTTGACATGCAATTAACTAGCAAAACCAAAAGTGAGGAGGATGAGGTGGAGGGTAAAGAGAGGGAGCAAGAGGTGGCAGCAGTATCTATTCCAGTTCTGAAGTGGCAGCCGGACAGCGACAGTGAGAGCAATCAGACTGATGTTGATGACGAGGACGAGGATTTTAAGCCCAAACAGTTACGACGCAGCGCACGAAAAGCCAAAGCCTGTACAGATAGCGAAAATGAATCAACATCTGGCCCTGCTTCCTTGCCTATTAAACGGCGACGTGGTCGCCCAGCACGTCTActcaaaaagaaaactatCAACGAAGAAGGACGGCATGTGTGTGAGGTTTGTGGAAAGAGCTTCTCGTGGTATCGTGATATGCAACGCCACTCGCGCATGCACTTCGAACAAGCAACGTTCTCGTGTGACACTTGTGGAAAGAGCTTCTTACGCAAAGATAAATTCATGTTTCATCTGCGTTCGCACGAAAAGCTTGCAGCCAAATCTCAGGCCATGCAATTCAGCAGCGAATGGCGCTTCGCTGAACGCCTCTACAGCTCCGGGCGGCTCAAACGTGCAGAGTGCAAGCTGTGTGGCTTAAAATACCAGCGTATAGGACAGCTGCGAGAGCATATGGCATGCCATAAAAGCATTGAGACTTTGTCTAAACTAGGACTGGAAAGTGATGTTGTCATAGAACAGTTTgccaaagagcagcagcaatccgACTTGGCGCTGATCAAGCAACAAGTGTGTACAGATATTGCCAAAGGACGTGGTCACCTGGACAAATACTGCTCTGTGGTCAACTCGTACGGCTATGAGCTCGGTCTTAGCGACTCAGACGAAGATTCAGCTGAGCCTAAATACCAGTGTCACATGTGTAAAATAAACTTCACGCGCAAATATCGCCTAATGCGGCACACACTGGAGGAACACACACAGGCGGACACGGCAGTATCTTGGCAACGCTGTGATGTTTGTCAAATTGGTTTTGTCTGCACCAAAATGTTGGAGCAACATCAACGGACACAATGCCTCAATAAACTGAAGCGTTACAGCTGCCCCAACTGCCCAGGTAAATTTATTTGGTTGCAGAACCTGGAGCAGCATGCGTGCTCGCAATATATAAAGCAGCACGACgggcaacgacaacaaaaacagtgTTGTCTCTGTGATACCCAAGTCGACAGCATGTTCGAATTACGTGCCCATTTGCTTAGCCATCAAGATGGACGTACTGGCATACATCCAGAGCATCAGGCTACCTTCTTTCGCACCTACTATCCCAATGGCCTTGACTGCAGTTTATCTGAGCTGAGTGCACGAATAGCTGCCGATTTCCAGGCAGAAGACTATGGGCGATACTTTAATGCCGGAACGAATAAGGGCGAGGAGCTCGATTTCTTTGCATCGGACACTGATTTGAGTGAAGCGGAACATCTGAGTTCTGATGGTACGCTACACATATGTTGCCTGTGTGGCGAGACAAAAACGCGCCTGAGTCAATTGCTGGAGCATCAGCATATCCAGCATAGTGAGGGAATAGAGAGGTTACCATACGTCTGTGAGGACTGCAATTTGAGTTTTGTAGCTAACGCGCTGCTCCAACAGCATCGCCGACGTGTCTGTGCCAAGCAGCATGCCAAGTACAACTGCCAGCAATGCAGTCAGCGCTTTTACTGGCATTCCAATTACGAGTTGCATATACGTCTGCAACACGAGACTCAGGCCGAACTGCAGGCTGATGTTAATGGACAAGACCGGCAGTCAAGCATGCGGAGCAAGCGTCAGTCGAAAGGTGCCAAGTTGCAGTGCGGCGAATGCGAAAAGGTGTTCATCTGGCCCAAGGATTTGACACGTCACAAGCGCCTACACCAGCCACAGGCTTTGGCACAATACCAATGCCTGCACTGTGATCGCAAGTTCCATCGCAAGGATGGGCTTAAGTCCCATATGCGAGTGCATGGCGAACAGAAGGTTTTTGCATCGGTTGCTAGTGAACAAGTTCCTTCCACGCTGCAGCGCATGCCAATGTTGCTGACTCAACTGTGTCGACCTCATGGCTGCAAGCAAATTCAATGCATGATATGTCTCTCGCATCATACCAAGATATCTGATCTACGTACGCATTTGCTTAATCATCAGTATTTGGTCAAGTTTGAAGAGGAGCGAAGCCAATCGGAAAGTATAGCGAGCATATCACGTTCTCTATATCCAGAGCTGGCCACACCTTTggaacagcagcaattaaTCGAACGCATTCAAAGTGATGTGGCAAAAGGCGAGGAGCTCGAAAGATTCATATCCATTACCAACGAGGCGGGTATTGAGCTCAGTCTGGATACCAGCGAAACGGAAACCGATTCGGACTCTGCTGAGACAGTTAGAAGCAACAGTGGACAAGTCTATAGCTGTGAGCTGTGCCAGCTGAAGGTATCTCGCAAGCATCAGCTCTACGCCCATGAGCTGGAGCAGCATTCGTGGCAGCAGGCAACCCGTGTTTGTGGCTATTGTCAGGCGAGATTCGTAAATGAGCAGTTACTAGAGCATCACTATCGGACGCTATGTCGCAACGTGCAACGGCGTTTCTTTTGCCGTAAATGTCCGCTACGCTTCCGCTGGCGCGAGAATATGAAGCTGCATTTGGATGTGGCGCACAACGAAGGCAGAGGTGATCAATCGAACTCGGACATCAAGTTAAACGGGACGCGCCTCTTACCCAGTGTTAGTTACGACTGCACTGAATGCAATCGTagctttaaaatgcaaaaggaTCTCACCAGACACACTCTCATGCATGCCCAGGAAACGAGTATTTATCGTTGTCGCTGGTGTGCACGACGGTTCTATCGCCAGGCCAATCTGCTGCAGCATATTGAGCGGCACGGCATTAGCGCCGAACAGCTGCCCTATGCTGAGGCTCTGCTCAATGCCAGTCGTCATCCGCACGGTCAGAAGTGTATCCAGTGCAAGGTGTGTAACGTGACCTACCCCACCATTGCTGCGTTGCGCGCCCATATACAATCAGCTCCAGCAGGCACACATCATGAGTATGGATCGTTGCTCAATTATTCCATAACCAATCAGCTGGGATATGAGCTGCATCTAGAAGACTCGGAAACGGATGAGGAAGCTAAGCCCCCAGGCACGCCCATGCATTACACCTGCAGCATATGTCAACTGCGCTGTGTGCGCAAGTTCGAgctgcatcagcatcagcaagCAATGCATCGTTTGGAACGCATAACCGAAGGTTGCGATGACTGCATCTTTAAGAGTGTTTCCGCAGATCTCATCGCCTATCATCGACGCGTCTTGTGCAATAATACGGagaaaaatttcaaatgctcCAAGTGTGGCTACAAGTTTATGTGGGAAACGAATTTGTTGCAGCATATGGAGTTGCAGCACCTCAACAGCGAAAGTAGCGAATCGCACCAGAATGCAAACACTTTGCGTGTTCCGGAGGTACCCAATGCAGAGTGCCAGATTTTTCAGTGCGGTCAGTGCCCTAGTAAATATAATCGCAAGGATCGCCTTACTGCACATATAAAGAAATGTCACGCAAAGGGAACAAGTGGCCCCACGGATGCGGCAGCTAAGCTAATGAAGAATTCAAACAGTACCAAGCAGCAGAAAAGCTTTCTTTGTGCATTCTGCGGCAAGGCGGTTAGCTCCTCATCAAATCTGATTATACATATACGTCGCCATACTGGCGAGAAGCCATTTAAATGTGACTACTGCGACATGGCATTTCCACGATCCTCTGATCTGCAGTGCCATCGACGCACCCACACAGGCGAGCGGCCGCACGTTTGCACCGTTTGCAAGAAAGGCTTTGCCCGATCCTACAAGCTACAGCAACACATGCGCATCCACAATGGCGAACGACCATACAAGTGCACATATTGCGATAAGAGTTTTACTCAGTCAAATGATCTGACGCTTCACATTCGACGGCACACCGGGGAGCGGCCCTATCAGTGCAATACTTGCGGCGAACGATTCATACAAGGCACAGCCCTGAAGAATCATCGCCTACAACAGGGACACCACGACACGGAAGTGGACCAGGTCAAAGATAACTAA
Protein Sequence
MLPTDICRTCTLHDDSLFPLATRADKYANKSLNDMLLELTQIDPLQEHTDDSLPQNLCMCCLHKLEAAYAFVLQARQAQEQFLQQLHKGLQTQCLDEMPIDINLQHIKTETVVDMQLTSKTKSEEDEVEGKEREQEVAAVSIPVLKWQPDSDSESNQTDVDDEDEDFKPKQLRRSARKAKACTDSENESTSGPASLPIKRRRGRPARLLKKKTINEEGRHVCEVCGKSFSWYRDMQRHSRMHFEQATFSCDTCGKSFLRKDKFMFHLRSHEKLAAKSQAMQFSSEWRFAERLYSSGRLKRAECKLCGLKYQRIGQLREHMACHKSIETLSKLGLESDVVIEQFAKEQQQSDLALIKQQVCTDIAKGRGHLDKYCSVVNSYGYELGLSDSDEDSAEPKYQCHMCKINFTRKYRLMRHTLEEHTQADTAVSWQRCDVCQIGFVCTKMLEQHQRTQCLNKLKRYSCPNCPGKFIWLQNLEQHACSQYIKQHDGQRQQKQCCLCDTQVDSMFELRAHLLSHQDGRTGIHPEHQATFFRTYYPNGLDCSLSELSARIAADFQAEDYGRYFNAGTNKGEELDFFASDTDLSEAEHLSSDGTLHICCLCGETKTRLSQLLEHQHIQHSEGIERLPYVCEDCNLSFVANALLQQHRRRVCAKQHAKYNCQQCSQRFYWHSNYELHIRLQHETQAELQADVNGQDRQSSMRSKRQSKGAKLQCGECEKVFIWPKDLTRHKRLHQPQALAQYQCLHCDRKFHRKDGLKSHMRVHGEQKVFASVASEQVPSTLQRMPMLLTQLCRPHGCKQIQCMICLSHHTKISDLRTHLLNHQYLVKFEEERSQSESIASISRSLYPELATPLEQQQLIERIQSDVAKGEELERFISITNEAGIELSLDTSETETDSDSAETVRSNSGQVYSCELCQLKVSRKHQLYAHELEQHSWQQATRVCGYCQARFVNEQLLEHHYRTLCRNVQRRFFCRKCPLRFRWRENMKLHLDVAHNEGRGDQSNSDIKLNGTRLLPSVSYDCTECNRSFKMQKDLTRHTLMHAQETSIYRCRWCARRFYRQANLLQHIERHGISAEQLPYAEALLNASRHPHGQKCIQCKVCNVTYPTIAALRAHIQSAPAGTHHEYGSLLNYSITNQLGYELHLEDSETDEEAKPPGTPMHYTCSICQLRCVRKFELHQHQQAMHRLERITEGCDDCIFKSVSADLIAYHRRVLCNNTEKNFKCSKCGYKFMWETNLLQHMELQHLNSESSESHQNANTLRVPEVPNAECQIFQCGQCPSKYNRKDRLTAHIKKCHAKGTSGPTDAAAKLMKNSNSTKQQKSFLCAFCGKAVSSSSNLIIHIRRHTGEKPFKCDYCDMAFPRSSDLQCHRRTHTGERPHVCTVCKKGFARSYKLQQHMRIHNGERPYKCTYCDKSFTQSNDLTLHIRRHTGERPYQCNTCGERFIQGTALKNHRLQQGHHDTEVDQVKDN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00509945;
90% Identity
iTF_00599720;
80% Identity
-