Dbus003653.1
Basic Information
- Insect
- Drosophila busckii
- Gene Symbol
- PBRM1_1
- Assembly
- GCA_011750605.1
- Location
- NC:8705445-8710655[+]
Transcription Factor Domain
- TF Family
- HMG
- Domain
- HMG_box domain
- PFAM
- PF00505
- TF Group
- Other Alpha-Helix Group
- Description
- High mobility group (HMG) box domains are involved in binding DNA, and may be involved in protein-protein interactions as well. The structure of the HMG-box domain consists of three helices in an irregular array. HMG-box domains are found in one or more copies in HMG-box proteins, which form a large, diverse family involved in the regulation of DNA-dependent processes such as transcription, replication, and strand repair, all of which require the bending and unwinding of chromatin. Many of these proteins are regulators of gene expression. HMG-box proteins are found in a variety of eukaryotic organisms, and can be broadly divided into two groups, based on sequence-dependent and sequence-independent DNA recognition; the former usually contain one HMG-box motif, while the latter can contain multiple HMG-box motifs. HMG-box domains can be found in single or multiple copies in the following protein classes: HMG1 and HMG2 non-histone components of chromatin; SRY (sex determining region Y protein) involved in differential gonadogenesis; the SOX family of transcription factors [1]; sequence-specific LEF1 (lymphoid enhancer binding factor 1) and TCF-1 (T-cell factor 1) involved in regulation of organogenesis and thymocyte differentiation [2]; structure-specific recognition protein SSRP involved in transcription and replication; MTF1 mitochondrial transcription factor; nucleolar transcription factors UBF 1/2 (upstream binding factor) involved in transcription by RNA polymerase I; Abf2 yeast ARS-binding factor [3]; yeast transcription factors lxr1, Rox1, Nhp6b and Spp41; mating type proteins (MAT) involved in the sexual reproduction of fungi [4]; and the YABBY plant-specific transcription factors.
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 1 1.1e-15 5.2e-13 48.7 0.0 2 66 1304 1368 1303 1371 0.94
Sequence Information
- Coding Sequence
- ATGCTAAGTCGCAAGCGTCGCGCCAGCTCTATATCGAGCCGGCAAGACGAGGATCCGCTGTTACTCGACGACTCAACACCCGAACAGTCGCCGGTGCAGCAGACGACACAATCGGCGCGAAAAAAGAGACGCTTGGACCCTGCAGAATTATGTCAACAGCTGTACGACTCGATAAGGAACATCAAGAAAGACGATGGGTCCATGCTATGCGATACGTTTATAAGAGCGCCAAAGCGCCGGCAGGAACCGAGCTACTATGACGTGGTTGTCAATCCCATAGACTTGCTTAAGGTGCAGCAGAAACTAAAAACAGACTCCTATGACGATTTGTATGACATGATGAACGACCTGGAACTGCTAATAAGCAACGCCAAGGCTTTCTACAAGCCAGACTCAGCGGAATACAGGGATGCATTGACATTCTGGCAACATATACAGGCGCAGCGTCACCGCATAATGGAAGCCAATGGCTTTGCAGAGGAGGAGCCACGTGCTAAGCGTGCACCGCGCAATACACGCCGGTTGACAACCAGCACAGAGCCAGGTGCTGGAGATCTTGACGATGATTGCAATCAGTATGAAGAGTTATTTGCAGCGGTCATGACAGCAACAGATCCAATGGGCGATAGGTCCATGCATCGCATGTTCCAACTGCTGCCGTCCAAGAAAATATATCCGGACTATTACGATGTTATAGAGCATCCCATTGACCTGCGTCTGATTGCCactaaaatacaaatgaatgcATACTCCTCGTTGGTGGAAATGGAACGCGACTTGTTGCAGATGACAAAGAACGCGTGTTTGTTTAATGAGCCGGGCTCGCAGATCTATAAAGATGCCAAATCGCTGAAGCGTGTTTTTACGCAGCGACGCATTGAGCTGGAGACAGGCAAAGGCAAGCCGGCTAGACGCATCAAGAGCTTGTCCAGTGCGGCTATAGCAGCTCTCAAAGAGGAAGTCGACAGCTCTGACGATGAGGACACCAGCAAAGAAGGCGAGGGACCCATGTGGGCGCTATTCGATCGGCTATACAATGCGCCTGGACATTCAGACCATCCAGGTGTAACTGGCCCTCCACTAGGCAACTCTCTATGGAAGCTGCCTGTGCGACGTTTTCATCCAGAGTACTTTGAGCTCATTAAGCGTCCCATTTCCATGAGtcaaatacacaaaaaattaaagaaaggCGAATATGCTAATATAAGTGACTTCACTGCTGACCTCTACCTAATGCTGGACAATGCCAAGAAAGCTTTTCCGGCCACGCATCGCACGCACAAggatgcaataaaaatgctaaagctTATGAATGCCAAGCTGGTTGAGGAATCATTTGAAGAAACAAGCGAAGTagaggatgatgatgatgaaacTTTTACGACCAGCACACAACCGGAACGTCGCAAGCCAGGCAGGCCGCGTGTGAACTCCAATACAAGCGCAGCACATACAACGCccaacaattcaaattcacCCAAGTCCAGCCGCATTCCCATCAATGCGGTTATTAAGAAGAAAATACTCACCATACAAAAGTATTTGGTAGATTATACTGTAAGCAATCGTCGtctaattgaaatgtttatgGAGAAGCCACCGCGCAAAGTCTATCCGGACTACTATGAGATCATACAAAACCCCATAGACATGAATACCATAGAGCATAATATACGCGCGGATCGCTATGCCACAGTCGAGGATGTGGTGGCCGATTATCGTCTGATGTTTAACAATTGCCGGCAGTACAATGAGGAGGGTTCCTATATCTATGAGGATGCAAACACGCTGGAGCGCGCTTTGAATGAAAAGTTAAAGGAATTCCCAGGACTGGTGGAAGTCAAGCGTCCACAGCAAAAGTACAATAGGCTGGGACGCAAATCCAAAGTGGCGGATCGCGAGCGTCTTTGGCAGTTTTATGAAACGCTGCGCGACTATCAAGAGCCCAAGGGCAAGCGTCAGTTGTCcttaatatttacaaagctGCCCAGCAAGAGCGACTATCCGGAGTACTATGACATTATCAAGCAGCCCATGGATATGGAGCGCATTTcgcaaaagcttaagcaaggCGCCTATGATAGCGTGGATGAGCTGGCGGCAGATGTACTGCTCATGCTGGAAAACGCTTGCAAATACAATGAGCCCGACTCGCAGATCTACAAGGACGCATTGGTGTTGCAACAGCTTACGttgcagctaaagcagcagctgcgcactGAACGCGATGCTTTGCCAGATGTGCCGTTGGCTGTGCAGGAGTTGTTCGTTAGTATATTTACCTCGCTTTACAATCATCAGGATGAGGAAGGTCGCTGTTACTCAGACTCTTTGGCTGAGCTGCCGGAATACGACGAGTTAAGCAAGGACGATGGCAGCAAAGTGCGCGGCATTTCGCTAGACTTGGTCAAGCGTAGATTGGACAAAGGCGCCTACAAGCGCTTGGATGTATTCCAAGAGGACATCTTCGCCTGCATGCAGCGGGCGCGCAAATTATCGCGCACGGACTCTGACATTTTCCAAGATGCCATCGAGCTGCAAACATATTTCATACGCAAGCGTGACGAGCTCTGCAAGGATACGCTCAGCTCACCAGCGCTTAACTTCAGTCTGGAGCAACTGCTGGTGGAAGTGGAGCTCATGCGCACGCAGAAAGCAGCGCAGGAGGTGCAGGAGCAAGAGCAGGAAAAGGAAAAGCACGAGTTTCAGGGCGAGAGCATGACCATCAACCAACAGGTCTACTCTCCAGGCGATTATGTCTATGTGCAGATCCCGGATAACAAAATACCCAGCATAGCCTGCATTGAGCGTCTCTGGACAACGCCGGGCAATGAAAAGTTAATGCAGGCGGGTATCTTTCTACGTCCACATGAGACGTACCATGTGACCACACGCAAGTTTTTGGAAAAGGAAGTCTTCAAGAGCAGCATTTCGCAAACCATTTCGATGGACAAGGTGCTGGGTATGTGCCATGTCATGCCCATAAGAGATTACATCAAGCTGCGGCCGGAGGGCTTGCCGGAGAAGGATGTGTTTGTCTGCGAATCGCGCTACAACCTGCCAGGACGCTGTTTCAAGAAACTCAAAAGCTGGTCCAGCAACAATAGTTCCATAAAGTATGTGCCGCGTGAATCTCCACTGGAGCTGAAGCGCGTTATGTCGGTGTTCAAGGAGCGCATAGAGAAGCACAAGGGTGAGCTGGAGGAGCTCAAACTGCAGGAGGCAATGGTTGAAAAGGAGAAGCCTAATGTTAGCTGCGATGCGCCACCGCAGGCAGATGATAATAGCGTCTATTATCAGCAGTATAATACGATCTGCAGTGGGGTCATCAAGACGGGTGACTTTGTCTACGTTGCCACGCAAACTGGCAAACAATCTGTGGCGCAGGTGCAGCAAATATGGGAGCTCAATGGCAAGTCCTACTTCAAGGGTCCGTGGCTGTTGTCGCCCAGCGAGACTACGCCCAcgataagcaaacaattctatcgccaggagctgctgctcagcccCGTCGAGGAGGTCAGTCCAGTCATTGGCATTGTGGGTCGCTGCGCTGTGCTGGAGTATGCCGAGTTTATAAGCTCGCGGCCCACTGAGATAGCTGAGAGTGATGTCTACATATGTGAGTCAGTCTATGATGAAGTCAAGAAGGCGCTACGTAATCTGGTCGTAGGCAATCTACGCAAGTTCCAGCACAGTGCTGAGGTTACGGAGGATGAAGTTTTCTACTTCAAAACGCCCATCAAACCTGCCAAAGATGTAAAGAGCGAGATCAACGAACTCGCCATGCTGGAGGATTCCATGGATGGTGATACACCTTCGCTTAGCTCGGACATAGTTACAATTTCATCACCAGCGCCTTCTGTTAACTCAACGCCACTTACCTCCAAGTCCAAAGTCAAGGCAAACAAGAAAAGCCTCACGGGCTACATACTCTACTCCAGCGATGTGCGCAAGGGCATAAGTCAGAGTAATCCGGAAGCATCGTTTGGCGACATCTCCCGCCTGGTAGGCAATGAATGGAAGAATCTGCCTGCTAGTGTTAAACAAAGCTGGGAGGATCGTGCCAATAAGCTAAACGAAGAAGCCGCCGCTATGCGACGTGAGCTGGATGAGACTCAGCAGTGCGGCAGTCCAATGCCTCAAACGCTTGTTGCCACCAGCATACCGGACCAGCCCACTGGTCCTGCGCTCACCTATGAATGTCTTTGGGACAAGTGCGACTTTCAATTTGAGGAAATGGCCGATTGTACGGAGCATTGTCTGGCGGATGCTACGGGGCATATACAGCGTCATCCTCAAGCTGGCGTCGATGTCGAGTATGTTTGCTTGTGGCGCAATTGTCCGCGCATACGCAAATCCACGCAAGCTTTTCCCAATGTGCTGCGTCTCATCAAGCATGTGCGCGAAGTGCACTTGAGCAAGTGCGGCAAACCGCTGACTCTGATGGATCGCAGCAAGAACTTTGTGTCGCGCAAGCAGAAGCTGGCGGCACAGCATGGCGGCGTCACAGTGCCGCTGCCCGTAACCAATGCACTCTCGCCACGTGGCTCCATCACGGCTAATgcattggagcagcagcatgtgcagctgcaacagcagcatcataCACTGCAGACGCTCATTGCTGGTCCGCCAGCTGAGCCAATGTTTGTAAGTGTGCCGCCACGTGCTAATCGCGTCATCCATTCGGAGGCCTACATCAAGTACATTGAAAGCCTGCAAACGGGCGCCCATCTCAATGTGGCCAACTGCAATCACAACTGGCGTCGTCAAATCACGCATGTGACGCCTGCCCAGGTTAGCAAGCCTCAATTGCCGGAGCACTGGCTGGGACCCAATGTGCGCGATCGTGAGAATGTGGTCCAGGCTCTCTGCCACCTGCGCAACTTTATGCTGGACGATGTGCTGCACATACAGCGCAGCTGCAACTAG
- Protein Sequence
- MLSRKRRASSISSRQDEDPLLLDDSTPEQSPVQQTTQSARKKRRLDPAELCQQLYDSIRNIKKDDGSMLCDTFIRAPKRRQEPSYYDVVVNPIDLLKVQQKLKTDSYDDLYDMMNDLELLISNAKAFYKPDSAEYRDALTFWQHIQAQRHRIMEANGFAEEEPRAKRAPRNTRRLTTSTEPGAGDLDDDCNQYEELFAAVMTATDPMGDRSMHRMFQLLPSKKIYPDYYDVIEHPIDLRLIATKIQMNAYSSLVEMERDLLQMTKNACLFNEPGSQIYKDAKSLKRVFTQRRIELETGKGKPARRIKSLSSAAIAALKEEVDSSDDEDTSKEGEGPMWALFDRLYNAPGHSDHPGVTGPPLGNSLWKLPVRRFHPEYFELIKRPISMSQIHKKLKKGEYANISDFTADLYLMLDNAKKAFPATHRTHKDAIKMLKLMNAKLVEESFEETSEVEDDDDETFTTSTQPERRKPGRPRVNSNTSAAHTTPNNSNSPKSSRIPINAVIKKKILTIQKYLVDYTVSNRRLIEMFMEKPPRKVYPDYYEIIQNPIDMNTIEHNIRADRYATVEDVVADYRLMFNNCRQYNEEGSYIYEDANTLERALNEKLKEFPGLVEVKRPQQKYNRLGRKSKVADRERLWQFYETLRDYQEPKGKRQLSLIFTKLPSKSDYPEYYDIIKQPMDMERISQKLKQGAYDSVDELAADVLLMLENACKYNEPDSQIYKDALVLQQLTLQLKQQLRTERDALPDVPLAVQELFVSIFTSLYNHQDEEGRCYSDSLAELPEYDELSKDDGSKVRGISLDLVKRRLDKGAYKRLDVFQEDIFACMQRARKLSRTDSDIFQDAIELQTYFIRKRDELCKDTLSSPALNFSLEQLLVEVELMRTQKAAQEVQEQEQEKEKHEFQGESMTINQQVYSPGDYVYVQIPDNKIPSIACIERLWTTPGNEKLMQAGIFLRPHETYHVTTRKFLEKEVFKSSISQTISMDKVLGMCHVMPIRDYIKLRPEGLPEKDVFVCESRYNLPGRCFKKLKSWSSNNSSIKYVPRESPLELKRVMSVFKERIEKHKGELEELKLQEAMVEKEKPNVSCDAPPQADDNSVYYQQYNTICSGVIKTGDFVYVATQTGKQSVAQVQQIWELNGKSYFKGPWLLSPSETTPTISKQFYRQELLLSPVEEVSPVIGIVGRCAVLEYAEFISSRPTEIAESDVYICESVYDEVKKALRNLVVGNLRKFQHSAEVTEDEVFYFKTPIKPAKDVKSEINELAMLEDSMDGDTPSLSSDIVTISSPAPSVNSTPLTSKSKVKANKKSLTGYILYSSDVRKGISQSNPEASFGDISRLVGNEWKNLPASVKQSWEDRANKLNEEAAAMRRELDETQQCGSPMPQTLVATSIPDQPTGPALTYECLWDKCDFQFEEMADCTEHCLADATGHIQRHPQAGVDVEYVCLWRNCPRIRKSTQAFPNVLRLIKHVREVHLSKCGKPLTLMDRSKNFVSRKQKLAAQHGGVTVPLPVTNALSPRGSITANALEQQHVQLQQQHHTLQTLIAGPPAEPMFVSVPPRANRVIHSEAYIKYIESLQTGAHLNVANCNHNWRRQITHVTPAQVSKPQLPEHWLGPNVRDRENVVQALCHLRNFMLDDVLHIQRSCN
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00479458; iTF_00549525; iTF_00496578; iTF_00482211; iTF_00609862; iTF_00574028; iTF_00560241; iTF_00558642; iTF_00566770; iTF_00497364; iTF_00521332; iTF_00593081; iTF_00528026; iTF_00597341; iTF_00557185; iTF_00576322; iTF_00498851; iTF_00543720; iTF_00511253; iTF_00535289; iTF_00500286; iTF_00522149; iTF_00570373; iTF_00607045; iTF_00516968; iTF_00499563; iTF_00514155; iTF_00619819; iTF_00485837; iTF_00548781; iTF_00598861; iTF_00542415; iTF_00616175; iTF_00498128; iTF_00525105; iTF_00577041; iTF_00495091; iTF_00595923; iTF_00518418; iTF_00564628; iTF_00501781; iTF_00553014; iTF_00582936; iTF_00552281; iTF_00513436; iTF_01570211; iTF_00574788; iTF_00484418; iTF_00471589; iTF_00480837; iTF_00487271; iTF_00601031; iTF_00563880; iTF_00474478; iTF_00514865; iTF_00536020; iTF_00517686; iTF_00603321; iTF_00473756; iTF_00580702; iTF_00611327; iTF_01319012; iTF_00547333; iTF_00568231; iTF_00586655; iTF_00567513; iTF_00541739; iTF_00561013; iTF_00590949; iTF_00483668; iTF_00577759; iTF_00612052; iTF_00618376; iTF_00503246; iTF_00501023; iTF_00604069; iTF_00600294; iTF_00571117; iTF_00555826; iTF_00555062; iTF_00523672; iTF_00505382; iTF_00507590; iTF_00802822; iTF_00565353; iTF_00832137; iTF_00551563; iTF_00546630; iTF_00606283; iTF_00478700; iTF_00568954; iTF_00480140; iTF_00590214; iTF_00531630; iTF_00491490; iTF_00571874; iTF_00477994; iTF_00482955; iTF_00489352; iTF_00527284; iTF_00533080; iTF_00609144; iTF_01321899; iTF_01326372; iTF_01325641; iTF_01327145; iTF_01321168; iTF_01324089; iTF_01323354; iTF_01327867; iTF_01322623; iTF_01320448; iTF_00612790; iTF_00485111; iTF_00490053; iTF_00561733; iTF_00524394; iTF_00617622; iTF_00593815; iTF_00541049; iTF_00594524; iTF_00488640; iTF_00473037; iTF_01549550; iTF_00520609; iTF_00509794; iTF_00530242; iTF_00608418; iTF_00557890; iTF_00583655; iTF_01556100; iTF_00599558; iTF_00572576; iTF_00506087; iTF_00575559; iTF_00601767; iTF_00528781; iTF_00587373; iTF_00553711; iTF_00472341; iTF_00556504; iTF_00588815; iTF_00598127; iTF_00573296; iTF_00559466; iTF_00562449; iTF_00563153; iTF_00490756; iTF_00616878; iTF_00530930; iTF_00526554; iTF_00475195; iTF_00534557; iTF_00533778; iTF_00584402; iTF_00537491; iTF_00589524; iTF_00510517; iTF_00493622; iTF_00506839; iTF_00522935; iTF_00805943; iTF_00585944; iTF_00595224; iTF_00550873; iTF_00582233; iTF_00476602; iTF_00519898; iTF_00502501; iTF_00495835; iTF_00579260; iTF_00519136; iTF_00605551; iTF_00581512; iTF_00536745; iTF_00548043; iTF_00578517; iTF_00602563; iTF_00486545; iTF_00804367; iTF_01356111; iTF_00901478; iTF_00492209; iTF_00508305; iTF_00538206; iTF_00511985; iTF_00529544; iTF_00588123; iTF_00515574; iTF_00494365; iTF_00615537; iTF_01552433; iTF_01550977; iTF_01548834; iTF_01550256; iTF_01553943; iTF_01559737; iTF_01551710; iTF_01555391; iTF_01558271; iTF_01557540; iTF_01556812; iTF_01553204; iTF_01554677; iTF_01559011; iTF_00592371; iTF_00539638; iTF_00596635; iTF_00544468; iTF_00550229; iTF_00614882; iTF_00481518; iTF_00566062; iTF_00545942; iTF_00579958; iTF_00487991; iTF_00503966; iTF_00477315; iTF_00585174; iTF_00509079; iTF_00614163; iTF_00919031; iTF_00915309; iTF_00914481; iTF_00916213; iTF_00918069; iTF_00919799; iTF_00917185; iTF_00540344; iTF_00803576; iTF_00805160; iTF_00512697; iTF_00554361; iTF_00516236; iTF_01319737; iTF_00338314; iTF_00337500; iTF_00336709; iTF_00339126; iTF_00335863; iTF_00504666; iTF_00619130; iTF_00591677; iTF_00607773; iTF_00904730; iTF_00532348; iTF_00538941; iTF_00470846; iTF_00610627; iTF_00569662; iTF_00525858; iTF_00545215;
- 90% Identity
- -
- 80% Identity
- -