Basic Information

Insect: Drosophila burlai
Gene Symbol: -
Assembly: GCA_008042655.1
Location: VNJT01005983.1:3134-5275[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 0.036 2.8 8.7 0.7 1 23 325 348 325 348 0.96

2 10 1.4 1.1e+02 3.7 0.5 6 23 358 375 358 375 0.96

3 10 1.8e-06 0.00014 22.2 0.7 1 23 381 403 381 403 0.98

4 10 0.00026 0.02 15.4 4.2 1 23 411 434 411 434 0.97

5 10 0.00057 0.044 14.3 0.8 1 23 442 465 442 465 0.97

6 10 8.3e-05 0.0063 17.0 0.6 3 23 473 494 471 494 0.92

7 10 0.0011 0.086 13.4 0.0 2 23 506 528 505 528 0.97

8 10 1.3e-05 0.001 19.5 4.2 1 23 535 558 535 558 0.96

9 10 5.7e-06 0.00044 20.6 0.6 1 23 564 586 564 586 0.98

10 10 7.1e-05 0.0055 17.2 1.3 1 23 592 615 592 615 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	0.036	2.8	8.7	0.7	1	23	325	348	325	348	0.96
2	10	1.4	1.1e+02	3.7	0.5	6	23	358	375	358	375	0.96
3	10	1.8e-06	0.00014	22.2	0.7	1	23	381	403	381	403	0.98
4	10	0.00026	0.02	15.4	4.2	1	23	411	434	411	434	0.97
5	10	0.00057	0.044	14.3	0.8	1	23	442	465	442	465	0.97
6	10	8.3e-05	0.0063	17.0	0.6	3	23	473	494	471	494	0.92
7	10	0.0011	0.086	13.4	0.0	2	23	506	528	505	528	0.97
8	10	1.3e-05	0.001	19.5	4.2	1	23	535	558	535	558	0.96
9	10	5.7e-06	0.00044	20.6	0.6	1	23	564	586	564	586	0.98
10	10	7.1e-05	0.0055	17.2	1.3	1	23	592	615	592	615	0.97

Sequence Information

Coding Sequence: ATGCTCGCCTGCGTGCTGTGCTTAGTTTGCTCCGATGGCGGCTACCCGCTGCTGTCCGCCGAGGGCGTCCGGCTAAACATTAAGGAGACCATCAACAAACACTTTTCGTTTTTCGAGGTGCTCACTGCTGACGGTGATGCCGCGGTCTGCCGGGAGTGCTGGCAGTGCATCAGCAGCTTCGATGAGTTCCACCAACGGGTCTCCAGGCTTCACCAACAGCCGGGCAGAGACGACTCAAAAAGCGTGGCTATTGAGTTCTGTGCCGAAACGGAGGAGGCCATCAATCCTCTCTTTGCCGTTGAACTGGATGCCTTGGCAGAGGACTTCTTCGCCCCTAACGAAGTGAAGGTGGAGGTTAACGAGCTGGAACCTCTGCCCAAGGTGGAGCTACTCAAGGACCCAGTCAAtacgaaaaggaaaacaggcGCCACCAAGCGTCGGGGTTCCCAAGCCGCAGGTCTATCCCAGCCCAAGCGTcgcattaaaaatgaaaaaattgtGGATAGTGATTCGGATGTGCCTCTGGCGAAGTTAGTGGGCGCAGAGAAAAAAACCGGGACCAACGGACAGGCAGGGATCAACGAACAGAGCAAGGGACAGCCGCTGCAGAGGAGCACGAGACGTGGTAGGCCACCAAAGGCCAAGCCAGTGACTCCTGCGTCTCCCAAAAAAGAACTTGAGTCGGATAAAGAAGACCACGACGTAAATTTCCTGGATTTCCTGACCGCAGATCCCGTTTCGGGCACTGACGACAGCTCCAGTTCCTCCAGCGAAAGCAGTGACGATGACTCAGACAACGAGCCGGAGGAACGGTATGCCAAGATCCCTAGGCGCGTCGTTGTGAAGCccaaaaaatatcgcaaacgCGAGAAACCCTTGGTCCCACCCAACAAGATGAGTCGTGAGGAGATCGAGCAACgaaaacagcagcaggaagtcTACGATAAGATTATCCTGCAGTTCTTTAAGAAGTTCTCCTGCCACATTTGCAACCTCCTCGTTCAGAACCTTTCGGACATGCGACTCCATCAGCGGGATGCCCACAACATAAAATCGGGCTTCATCCAGTGCTGCGGGAAAAAATTCCACAGACGCAAGATTTTGGCGGAGCATGTGTTGGTCCACAAAAATCCGGAGCACTTTATGTGCTCTCATTGCGGCCGGGTGTTCCCAGATTCTCGCTCTCTGGAGGTCCACGAGCAGACGCACGTTAACCCGGAGAAGCCGATGTTCCATTGCGAAAAGTGCCCCAGGAGCTTTACCAGCAAGATGTCCCTTGAGTATCACTTTATGACCAAGCACGTACCCAAGTCCGAGTTCAAATACAACTGTCCAGAGTGTGACAAGAAGATTCCCACGATGCGCAAGCTGAAAGAGCATCTTCGCTACAGGCACAACCCGGAAACGGCCATAATCTGCGACAAGTGCGGCAAAACATTGCCTCCCAAATCGAATCTCAAGAAGCACCACGAACTGGAACATTCCGAGGAGCCACTTCCGAAGCCCGATCCCGTGCAGTGCGAGATCTGCGGAGCCTGGCTGAAAAATCCGTCCGGGCTGAAGAAGCACATGACCACTGTGCACGAGCCGAAGGACAAGGAGCACCGCTGTCCCATATGCAACAAGACGTCCGTCAATTCCACATCCCTCAAGCGTCACATCAGACACAACCACCAGTGCGAGCGGAAGTTCAAGTGCGGACTGTGCGAGAAGGCCTTTAAACGGCCGATGGATCTCAGGGAACATACGTCCACGCACACCGGCGAGGTGCTCTACACCTGCCCCAACTGTCCCATGACGTTCTTCTCCAACGCCAACATGTACAAGCATCGCCAGCGACTCCATCGCGCCGAATGGGAGGCGGACCGGAAGAAGCCGCTGCCGCCGAACATCATGAAGTTATCGCAGGGCCCCACCACAGTCGGACCAGACGGAATAACATTAACTTTTTCATATTTACCACAGCTATAG
Protein Sequence: MLACVLCLVCSDGGYPLLSAEGVRLNIKETINKHFSFFEVLTADGDAAVCRECWQCISSFDEFHQRVSRLHQQPGRDDSKSVAIEFCAETEEAINPLFAVELDALAEDFFAPNEVKVEVNELEPLPKVELLKDPVNTKRKTGATKRRGSQAAGLSQPKRRIKNEKIVDSDSDVPLAKLVGAEKKTGTNGQAGINEQSKGQPLQRSTRRGRPPKAKPVTPASPKKELESDKEDHDVNFLDFLTADPVSGTDDSSSSSSESSDDDSDNEPEERYAKIPRRVVVKPKKYRKREKPLVPPNKMSREEIEQRKQQQEVYDKIILQFFKKFSCHICNLLVQNLSDMRLHQRDAHNIKSGFIQCCGKKFHRRKILAEHVLVHKNPEHFMCSHCGRVFPDSRSLEVHEQTHVNPEKPMFHCEKCPRSFTSKMSLEYHFMTKHVPKSEFKYNCPECDKKIPTMRKLKEHLRYRHNPETAIICDKCGKTLPPKSNLKKHHELEHSEEPLPKPDPVQCEICGAWLKNPSGLKKHMTTVHEPKDKEHRCPICNKTSVNSTSLKRHIRHNHQCERKFKCGLCEKAFKRPMDLREHTSTHTGEVLYTCPNCPMTFFSNANMYKHRQRLHRAEWEADRKKPLPPNIMKLSQGPTTVGPDGITLTFSYLPQL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00490241;
90% Identity: iTF_00490241;
80% Identity: -