Basic Information

Insect: Drosophila burlai
Gene Symbol: Hr39
Assembly: GCA_008042655.1
Location: VNJT01010638.1:540077-542963[-]

Transcription Factor Domain

TF Family: SF-like
Domain: zf-C4|SF-like
PFAM: AnimalTFDB
TF Group: Zinc-Coordinating Group
Description: The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 3 0.11 1e+03 -1.1 6.8 43 159 190 313 168 393 0.51

2 3 2.7e-10 2.5e-06 27.2 0.0 1 31 478 508 478 520 0.87

3 3 7.6e-84 7.2e-80 269.5 0.4 182 408 519 736 514 736 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	3	0.11	1e+03	-1.1	6.8	43	159	190	313	168	393	0.51
2	3	2.7e-10	2.5e-06	27.2	0.0	1	31	478	508	478	520	0.87
3	3	7.6e-84	7.2e-80	269.5	0.4	182	408	519	736	514	736	0.96

Sequence Information

Coding Sequence: ATGCCGAACATGTCCAGCATCAAGACGGAGCAGCAGAGCGCTTCTCTCGGAGTAACTGGCGGTGGCTATCAGCTGCCGGTCAATATGTGCACCACCACCGCGtccacgacgacgacaacgctgggaggaggaggtggaggaggagtaaGTGGCGGAACCACTGGATCGAGGCACAATGTGTCCGTGACTAACATCAAGTGCGAGTTGGACGAGCTGCCCACGCCCAACGGCAACCTGGTGCCGGTGATTGCCAACTATGGTCACGGCAGCCTGCGCATACCGCTGAGCGGCGGTCCGCCACCCAACCACGAGGAGGAGTCCGATTCGGAGGCCGAGCTGGCGAACATCGAGAACCTGAAGGTGCGCCGGCGGGCGGCGGACAAGAACGGGCCGAGGCCCATGTCATGGGAGGGCGAGCTGAGCGAACCGGAGGCCAATGGCGGCGACGAGGAGCTGATGGAGACGGAGCCGACGATTAAAAGCGAGTTACTGACCAACGCCGGAGCAGCCCTGCAGCCCGCTTGTGCTCTGCAGCCGATCAAGACCGAGCTGGAGAACATCGCAGGCgaacttcagcagcagcagcagcagcaactgcaactgcaactgcagcagggAAAGGCCTTCCCCCtgaccagcagcaccaccaccacctcccaATCGCTCTCGACGAACCCCAAACTTAAGCTGGCGCCCACGCAAAGTGATCCCATTAATCTCAAGTTTGAACCGCCGCTGGGTGACAACTCGCCGCTGCTGGCCGCCCGCAGCAAGTCGAGCAGCGGTGGACACCTGCCGCTGCCCGCGAATCCCAGTCCCGACTCCGCCATACATTCCGTCTACACGCACAGTTCGCCATCGCAGTCGCCGCTGACCTCGCGCCACGCCCCCTACACGCCCTCGCTGAGTCGGAACAACAGCGACGCCTCGCACAGCAGctgctacagctacagctccGAGTTCAGCCCCACCCACTCACCCATCCAGGCGCGACATGCCCCCCCAGCGGGCTCGCTATACGGCAACGGCGGCGTGCATCATCACAGTGTGTTGTATCGCCCGCTGAAGGTTGAGGCCTCGTCCACGGGGCCACCGTCCGGCAGCCAGGAGGCGCAAAATTTGAGCATGGACTCCATTTCCAATGGTTTGGATGCAACGGGTTCGGGTTCATCGCTGCCCGCCTCGCCGGCCGGCATTTCGCGCCAGCAGCTCATCAACTCACCGTGTCCCATTTGCGGCGACAAGATCAGCGGCTTCCACTACGGCATCTTCTCCTGCGAGTCCTGCAAGGGGTTCTTCAAGCGCACCGTGCAAAACCGCAAGAACTATGTGTGCGTGCGCGGCGGGCCCTGCCAGGTGAGCATCTCCACGCGCAAGAAGTGCCCGGCCTGCCGGTTCGAGAAGTGCCTGCAAAAGGGCATGAAACTGGAGGCCATCCGCGAGGACAGGACGCGCGGCGGTCGCTCCACCTACCAGTGTTCGTACACGCTTCCCAACTCGATGCTCAGCCCGCTGCTAACCACTTCATCAGGCGCCAACCagggacagcagcagccgcagccgcagctgaCCAACCCACTGCTGGCCAGTGCCGGTCTCTCGTCCAACGGCGAGAACGCCAATCCCGACCTGATTGCCGATCTCTGCAACGTGGCCGACCATCGCCTCTACAAGATTGTCAAATGGTGCAAGAGTTTGCCGCTTTTTAAGAACATTTCGATCGATGATCAGATCTGCCTGCTCATCAATTCGTGGTGCGAACTGTTGCTCTTCTCCTGCTGTTTCCGATCGATCGACACTCCCGGCGAGATAAAGATGTCGCAAGGCAGAAAGATAACGCTGTTGCAGGCCAAATCAAATGGCTTGCAGACCTGCATTGAACGGATGCTCAATCTGACAGATCACCTACGGCGATTACGCGTTGACCGCTACGAATATGTTGCCATGAAGGTGATTGTCCTGTTGCAGTCAGACACCACGGAGCTTCAGGAGGCAGTAAAGGTTCGGGAGTGCCAGGAGAAAGCGTTGCAGAGCTTGCAGGCGTACACCTTGGCCCACTATCCCGACACGCCGTCAAAGTTCGGGGAGCTGCTGTTGCGCATTCCTGATCTGCAGCGTACGTGCCAGTTGGGCAAGGAGATGCTGACGATCAAGACTCGCGATGGCGCCGATTTCAACTTGCTGATGGAGCTCTTGCGCGGAGAACATTGA
Protein Sequence: MPNMSSIKTEQQSASLGVTGGGYQLPVNMCTTTASTTTTTLGGGGGGGVSGGTTGSRHNVSVTNIKCELDELPTPNGNLVPVIANYGHGSLRIPLSGGPPPNHEEESDSEAELANIENLKVRRRAADKNGPRPMSWEGELSEPEANGGDEELMETEPTIKSELLTNAGAALQPACALQPIKTELENIAGELQQQQQQQLQLQLQQGKAFPLTSSTTTTSQSLSTNPKLKLAPTQSDPINLKFEPPLGDNSPLLAARSKSSSGGHLPLPANPSPDSAIHSVYTHSSPSQSPLTSRHAPYTPSLSRNNSDASHSSCYSYSSEFSPTHSPIQARHAPPAGSLYGNGGVHHHSVLYRPLKVEASSTGPPSGSQEAQNLSMDSISNGLDATGSGSSLPASPAGISRQQLINSPCPICGDKISGFHYGIFSCESCKGFFKRTVQNRKNYVCVRGGPCQVSISTRKKCPACRFEKCLQKGMKLEAIREDRTRGGRSTYQCSYTLPNSMLSPLLTTSSGANQGQQQPQPQLTNPLLASAGLSSNGENANPDLIADLCNVADHRLYKIVKWCKSLPLFKNISIDDQICLLINSWCELLLFSCCFRSIDTPGEIKMSQGRKITLLQAKSNGLQTCIERMLNLTDHLRRLRVDRYEYVAMKVIVLLQSDTTELQEAVKVRECQEKALQSLQAYTLAHYPDTPSKFGELLLRIPDLQRTCQLGKEMLTIKTRDGADFNLLMELLRGEH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00492281;
90% Identity: iTF_00492281;
80% Identity: iTF_00492281;