Dbun010193.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila bunnanda
Gene Symbol
ftz-f1
Assembly
GCA_008042815.1
Location
VNKE01004325.1:160524-174617[+]

Transcription Factor Domain

TF Family
SF-like
Domain
zf-C4|SF-like
PFAM
AnimalTFDB
TF Group
Zinc-Coordinating Group
Description
The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 2 2e-19 1.7e-15 57.3 0.4 1 76 202 277 202 309 0.74
2 2 7.1e-71 5.9e-67 226.7 2.0 157 408 423 667 406 669 0.92

Sequence Information

Coding Sequence
ATGTTATTAGAAATGGATCAGCAACAGGCGACCTATATATTCCCGACAGGCTATCAGGACACCACCTCCTCGCATTCCCAACAAAGTGCTGGCGGCGGGGGcggaggtggcggcggcggcaatggcGGCAACCTCCTGAACGGCAGCTCCGGCGGCTCATCCGTCGGCGGTGGCTATATGCTCCTCCCACAGGCGGCCAGCTCCAgtggcaataataataataacactgGCGGTCACATGTCCTCCGGTTCGGTGggcaatggcggcggcggtaatGGTGGTAATGGTGGAGCTGGTGGCAACTCTGGCGGTCCGGGCAACTCGATGGGCGGCACCAGTGCCACGCCAGGACATGGCGGCGAGGTGATCGACTTTAAGCATTTGTTCGAGGAGCTGTGCCCCGTTTGCGGCGACAAGGTCAGTGGCTATCACTATGGCCTGCTCACCTGCGAGTCCTGCAAGGGTTTCTTCAAGCGGACCGTGCAGAACAAGAAGGTGTACACCTGTGTGGCGGAACGATCCTGCCACATTGACAAGACGCAGCGCAAGCGGTGTCCCTACTGCAGATTCCAGAAGTGCCTCGAAGTTGGCATGAAGTTGGAGGCTGTGCGAGCGGATCGGATGCGGGGTGGAAGGAACAAATTTGGACCGATGTACAAACGAGATCGGGCGCGGAAGCTGCAAGTCATGAGGCAACGGCAGTTGGCACTGCAGGCGCTTCGCAACTCCATGGGCCCGGACATAAAGCCAACGCCGATCTCGCCGGGCTACCAGCAAGCATATCCAAATATGAACATTAAGCAGGAAATTCAAATACCTCAGGTATCCTCACTCACCCAATCGCCGGACTCATCGCCCAGCCCCATTGCCATTGCGCTGGGACAGGTTAATGCCAGCACGGGCGGTGTGATAACCACGCCCATGAATGCCGGCAACGgtggcagtggcggcggcggcggcggcaatggtGGGGGTCTCAACGGTCCCAGTTCCGTGGGCAATGGCAatagcagcaacggcagcagcagcagtaccggcggcggcaataacaacggcagcagcacgGGCAATGGAGcgtccggcggcggcggcggcggtggaggcggaggaggaggtggtggtggcaacaatgcgggcggcggaggaggcggcagTGGCAATAACTCCGGTGATGGCCTGCATCGTAACAGTGGCCACGAGGCTGGAATAGGATCTCTGCAGAACACGGCCGACTCGAAATTGTGCTTTGATTCCGGCACACATCCATCGAGCACAGCCGATGCGCTAATCGAGCCATTAAGGGTCTCACCAATGATTCGTGAATTTGTGCAATCAATCGACGATCGGGAATGGCAGACGCAACTGTTTGCTTTGCTGCAAAAGCAGACCTACAACCAGGTGGAAGTGGATCTCTTCGAGCTAATGTGCAAAGTGCTCGACCAGAACTTGTTCTCGCAAGTGGACTGGGCACGGAACACGGTCTTCTTCAAGGACCTCAAGGTCGATGATCAAATGAAGCTACTGCAGCATTCGTGGTCAGACATGTTGGTCCTTGATCACCTGCACCATCGCATCCACAACGGCCTGCCCGATGAGACGCAGCTGAACAATGGCCAGGTCTTCAATCTGCTCAGTCTGGGCTTGTTGGGTGTACCACAGTTGGGTGACTATTTCAACGAGCTGCAGAACAAGCTGCAAGATTTGAAATTCGATATGGGCGACTATGTCTGCATGAAATTCCTAATCCTCTTGAATCCAAATGTGCGGGGTATTGTCAACCGGAAGACCGTTTCCGAGGGGCATGATAATGTGCAAGCCGCTTTGCTGGACTACACCCTCACCTGTTATCCGTCAGTTAATGACAAATTCAGTAGGCTAGTGAACATCTTACCGGAAATCCATGCCATGGCCGCACGCGGCGAGGAGCATCTGTACTCCAAGCATTGTGCCGGCAGTGCACCAACCCAAACGCTGCTCATGGAGATGCTCCATGCCAAGCGGAAGGTGTAG
Protein Sequence
MLLEMDQQQATYIFPTGYQDTTSSHSQQSAGGGGGGGGGGNGGNLLNGSSGGSSVGGGYMLLPQAASSSGNNNNNTGGHMSSGSVGNGGGGNGGNGGAGGNSGGPGNSMGGTSATPGHGGEVIDFKHLFEELCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNKKVYTCVAERSCHIDKTQRKRCPYCRFQKCLEVGMKLEAVRADRMRGGRNKFGPMYKRDRARKLQVMRQRQLALQALRNSMGPDIKPTPISPGYQQAYPNMNIKQEIQIPQVSSLTQSPDSSPSPIAIALGQVNASTGGVITTPMNAGNGGSGGGGGGNGGGLNGPSSVGNGNSSNGSSSSTGGGNNNGSSTGNGASGGGGGGGGGGGGGGGNNAGGGGGGSGNNSGDGLHRNSGHEAGIGSLQNTADSKLCFDSGTHPSSTADALIEPLRVSPMIREFVQSIDDREWQTQLFALLQKQTYNQVEVDLFELMCKVLDQNLFSQVDWARNTVFFKDLKVDDQMKLLQHSWSDMLVLDHLHHRIHNGLPDETQLNNGQVFNLLSLGLLGVPQLGDYFNELQNKLQDLKFDMGDYVCMKFLILLNPNVRGIVNRKTVSEGHDNVQAALLDYTLTCYPSVNDKFSRLVNILPEIHAMAARGEEHLYSKHCAGSAPTQTLLMEMLHAKRKV