Dbor015088.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila borealis
Gene Symbol
RREB1
Assembly
GCA_035045885.1
Location
JAWNOR010000297.1:330523-337549[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 13 0.0061 0.5 11.3 0.6 1 21 243 263 243 265 0.96
2 13 0.00035 0.028 15.2 0.2 1 23 275 297 275 297 0.98
3 13 8.4e-05 0.0069 17.1 7.3 1 23 303 325 303 325 0.98
4 13 0.07 5.7 7.9 1.8 2 20 552 570 552 572 0.93
5 13 0.0092 0.75 10.7 0.1 1 23 727 749 727 749 0.97
6 13 1.3e-05 0.001 19.7 0.7 1 23 759 781 759 781 0.99
7 13 0.00087 0.07 13.9 2.0 1 23 787 810 787 810 0.97
8 13 0.0031 0.25 12.2 2.0 1 23 1087 1110 1087 1110 0.95
9 13 9e-05 0.0073 17.0 0.3 2 23 1465 1486 1464 1486 0.97
10 13 0.15 12 6.9 6.3 1 23 1492 1515 1492 1515 0.97
11 13 9.8 8e+02 1.2 3.4 1 23 1650 1673 1650 1673 0.78
12 13 0.0088 0.72 10.8 0.5 3 23 1740 1760 1738 1760 0.96
13 13 0.0014 0.11 13.3 4.8 1 23 1766 1788 1766 1788 0.99

Sequence Information

Coding Sequence
atGCTGgccgcacagcagcagcagcagccacagcagcaacacacagcggcaacagcaacgggaGGCAGCACAGTAGCGCTCGAGGATGCGGGCTTGGAGCGGGCGCGCCGCGATTCGAGCACCTCGGAGTCCTCGCTGGAGCACCTGGACTTGAGCCGCACGCCAAAgaagctgagcagcagcagcggcgcgcCGCAGCCGACGTCGACGCCGCATGAGGCGACGTCGCGCAAGCGCAAGCtgcgccagctgcagcagccgcaacagttGCTCTCCGACGAGGacgagcaacagcagcagcagcagcagcagcagctgctggagcaGTCCGCGCAGCGACTGCGGCACAAGCAGCGACGCAGCGGAAAtgcagccgcagtcgctgccgctgccagcgCCAGCATCGTGGTCGACTACAGCGCCAGCGGCGATGCCAGTTCGCTGCGCAAAAAGTTTCGCCTGAAccgcagcagcgccagcagcatcAATGGCAACAACGGCGAGCTCTCCGAGTCCGGCTTTGTGGATGGCAGCGCGCACAGCGGTTATTTGCTCAGCGCCAGCAGCGCCGCGCAGTCAGCGtcggcagcgcagcagcagcagcaacaacagcagcagcagcagcagcaattggccTCAAGCAGCAGCTCCGGCGGCAGCTCGCCCCAGGGCCTTTACCACTCGAGCGCCGAGTCCGGCATCGGCGCCGGCGACGAGCACATGAAATATGTTTGCCCCATCTGCGAGGTCGTCTCGGCCACGCCCCACGAGTTCACCAATCACATACGCTGCCACAACTACGCCAACGGCGACACCGAGAACTTCACCTGCCGCATCTGCTCCAAGGTGCTGTCATCGGCCTCCTCGCTGGACAGGCACGTGCTGGTGCACACGGGCGAGCGTCCGTTCAACTGTCGCTATTGCCATTTGACATTCACCACGAACGGCAACATGCACCGGCACATGCGCACCCACAAGCAGCACCAGAcgacgcagcagcaacagcagcagcagcaacaacagacaccgcagcaacagcagacaccgcagcaacagcagacacCGCAGCAACATGCACCGCAGCAACatggacagcagcagcgacgccagcagcaTGGGGGCGCGGCAGCTGGGCGCGCGGAGAGCTACGAGAGCGATGCCAGCTGCTCGACGGATgtgtccagcagcagcagcagcagcgacagcagcaacagcagcaacaccaacaacaacaacaacaacaacaacaacaacagcgagcaaacgaacaagaacaacaacagcaacggagagcagcagcaactgttgctggcGTGCAAGCAGCGACGGCCGAAGAcgaacatcaacaacaacaatatcctCAGCGACGAGGAGCAGCCAAAGCAGCCAAAATCGGAGCCCGATGCAGAGCCGGAGCCAGAGCCGGAGCTGGACTCGGATGATGCGGAGAGCGTGGATGTGGCGCAGATGATCACGAGCACGCCGGATGTGGCCACATTGCTGGCAACTggcgacggcggcgacggcgacggcagcaCACGATCGAGCCCATCGCCGGGTCTGCAGAGCTGTCCGGCGTGCAATACGGGCGAGTTTGAGACATTGCCGGCGCTGTGCGCGCATCTGGATGCAGCGCATCCGGACATACCCGCCAAGTGTCGCGACTGCGATGTGATCTTTGCCAGCCATCGGCAGCTCCAGGCGCACAGCTGTCGCGgccagctgcagttgccgccgctgctcGGCGCCAGCAGCTCGCCGCTGCACAAGCTGGAGATGGTGGACCACGaccaggagcaggagcaggagcaacaGTATGCGAATGAGGAGGATGAGGAGGAGCTGGCGCACGGTGAGCAGCTGGCCAGCAGCGAGCAGCGGGATGAGTTCTTTCAGCAGCTCTATCTAAAGGGCAAAGCCGGCGGACTGCCGTCGCCCATCAAGCGGGAATTGTCCGAGCAGCGGCTGGAGCAGCGCCAGGATCGTCAGGATCTGGCCGATATACAGAGCATTTTGCATATGACCAGCTCCAGTTGCACGTCGAGTTTCCTGCGCAATTTCGAGCAGTCGGTGAACACGCCCTGCTCCAGCCAGTACAGCCTGGATGGTCGCGACGGCGAGGAGGAGGCCCAGGATGCGTTCACCAGCGAATTCCGACGCATGAAACTGCGCGGCGAATTCCCCTGCAAGCTATGCAGCGCCGTCTTTCCCAATTTGCGCGCCCTCAAGGGCCACAATCGGGTCCATCTGGCCGCCGTCGGCGCCGCCGGACCCTTTCGCTGCAACATGTGCCCCTATGCCGTCTGCGACAAGGCGGCGCTGGTGCGGCACATGCGCACCCACAACGGGGATCGGCCCTACGAGTGCGCTGTCTGCAATTACGCCTTCACCACGAAGGCCAATTGTGAGCGGCATCTGCGCAATCGGCACGGCAAGACGAGCCGCGAGGAGGTGAAGCGCGCCATTGTCTATCATCCGGCGGAGGATGCCAGCTGCGAGGAGGGCAACAAACGTCCAACAACGGGCCAGGACACGGACCTAGCCGAGCTCAGCTATCGTTCGCTCagtccgccgccgccgccggcccCGTTGCCCCCCTTGCCGACGGCATCGCATGAATCGCAGCTAAAGCACATGTTGCTGGCGGAACCGTGCGCCaagttgccgccgccgccgccgccaccgacgacgacggcgacgccgCTGAAGATACAGGTGAAGAGCTTGGATCAGCTGGTGGAGAAGCCGCTGGCGCCGCCAGCCATGGATCTTAGCATGGACGTGCTGGATCTGAGCAAGAAGCCCACACAGCAGCTGGAGCGCCAGCGCGAACGGGAGCGCGAACAGGAGCacgatctgctgctgctgcagcagcagcagcaacagttgcagcaacaGGTGCAACAGCAGGTGCAACAacaggtgcagcagcagcagctgtttaGCGCGGGAGATGCGACGACGCAGTatatgcagcagctgctgcgcaatCTCATGTTCCAGCAGACGCCGGGCTTCTCCTTCTTTGGCTACATGGCgccgccgacgacgacgacgacggcgacgtcggCGGAGAAATCAACGCAGCCGGGCACAAATCCAGGCCAGACGccggcaacagttgctgctggcaTGCCCATGGGCATGCCGGTGCCGGTGACCGTGCCGGTGCCAGCGGGCGGGCCCGTCAAGATGGTGATCAAGAACGGCGTCCTGATGCCCAAGCAGAAGCAGCGTCGCTACCGAACCGAGCGACCCTTCGCCTGCGAGCACTGCTCCGCCCGATTTACGCTGCGCTCCAACATGGAGCGTCACGTCAAGCAGCAGCATCCCCAGTACTATGCGCAGCGCCAGCGCAGCGGACACCATGTGATGCGCGGACGCGCCGCCAGCTCCAATgccgcggcagcagcggcggcagcagcagcagctgcggcggcagcagcagcagcagctgccatgTCGAAtctggcgcagcagcagcagcagcagcatgcgCATCCGCCCATTTCGGAGCAGGTGAAGTACGCGATATTGGCGCAGCAGCTGAAGGCGCGCAAGGACACGGATCTGCTGCACCAGGCGCTGGCGCACGGCTCCAGCAGTGCGCTGCTCCACttcaactacaacaacaacagcaacaacaacagcaacagcaacaacaacaataagcagcagcagccgccacaTCCCATCaatggagctgctgctgcggatgATGATGAGCCGCCCAAGCTGATCATAGACGAGGACGACgaggcggaggaggaggaggagtttGATGATACAGAGGAGGAgcacgaggaggaggaggagctcGAAATGGAAGAGGACGCGGATGAGGAGCAGCCGATCGCACAGCTGGATCAGCTCGAACTgcctgcggcggcggcggcgacgacggcgacgcaGCCACGCCCCGGCACGCCCATTGAGGCAGCCAAAAAGGTAGCGGAGAGCATACTGGAGCAGGTGATCAAGGCGCAGGCCAAGCCCGATCCGGAATCAGATGCCGTGGCCATGCCAACgcccacaacaacaagcacggccacgcccacaccggGACCGACCACAATGAAAACAATGATAGCCCAAGCAGAATCGGTGGCCAAATCCCTGAAAGATGTGGCCAGCTCACCGTTCAAGGACGAATCTCAGGATCTGGTGCCGGTGGCCAAGCTGGTGGACAACGCGACCAGCAATCAGGTCTCGTTCAACAGCTATTTCCGGCCCAGCGACGTGGCCAATCACATGGAGCAGAGCGACGAGGAGGGTCTAGTTGCCTCCGGCAGCGCCAGCGAGAGCAACAATTCCGGCACCGAGGAcgtcaccagcagcagctgcaacgaACCCAAAAAGAAGTCCGCCTACAGCCTGGCGCCGAATCGTGTCAGTTGCCCGTATTGCCAGCGCATGTTCCCCTGGAGCAGCTCGCTGCGTCGCCACATCCTGACCCATACGGGCCAGAAGCCGTTCAAGTGCTCGCACTGCCCGCTGCTGTTCACCACGAAGAGCAACTGCGACCGGCATCTGTTGCGCAAGCACGGCAATGTCGAGTCCGCGATGAGCGTCTATGTGCCCACCGAGGATGTCAGCGAACCGATACCCGTGCCCAAGTCCGTCGAGGAGATCGCCTTGGAGGAGCAGCGCCGACGCAAGGCCGCCGAAGCGGAGCGCGAACGCGAACgccagctggagctggagcggGAGCGCGAAAGGGAGCGCGACCGTAAAATCGAACGCGAacgagagcagcagcagcaacagcagctaatCCAGCAGCTGGCTGCGGCACAGCTACGCCAGCAACTGACCAacgccgcagccgccgccgccgccgctgccgccgccgcagctgcagccTCAGCAGCCGGTGCCGGAGTCGGAGGCGGAGCCGGCAACAGTCCAACAGCTGGCGGCGAGGGGAGCAACGGCAGCGAGCTGCCGTACAAATGTCATCTGTGCGAATTCTCGTTCGGGGAGCGGCTGCAGTGCCTCGAGCACATCAAGCAGCTGCATGGCCAGGAGTTTGccctgctgctggccaaaggCGCCATCGAAACGGAGACGCTCCAcgaccaccagcagcagcagcagcagcagccgtcgtCCAAtcccgcaacagcagcagcagcagctggctcCGAGGATGAATCGCTGGCGCCGTCGGGTCGCGGCAATGGCAAATATCCGGACTACAGCAACCGGAAGGTGATCTGTGCGTTTTGTGTGCGCCGCTTCTGGTCGACGGAGGATCTGCGCCGACATATGCGCACCCATTCCGGCGAACGGCCGTTCCAGTGCGAGATCTGTTTGCGCAAGTTCACGCTGAAGCACAGCATGCTCCGCCACATGAAGAAGCACAGCGGACGCAGTCACAATGGCGAGCAGGGCGCATCCGATTGTTCCGACGACGAGCAGATGGCCACGCCGCCCGGCACGCCCACACCAACGCCCATGGCCATGCCCAcgcccagcagcaacaacaacaacaacaacaacaacagcagcacttgccagaacaacaacaacaacaacagcaagcagAGCCTGCGTTTGGACAAGACGCCCGATTGGCGCCTGCAGAAGGACAAAATTGGcgatgccacgcccacagcgaCAGCAGCCGCCTTTGGCATGGCCAGCGGCGATCTGATTGGCAATCTGCTGGGCATCAGCGACCAGGGCATACTCAACAAGCTGCTCTCCTCCGCGGACGAGGCGGCCAAGCTGCTGGGCGTGGAAAAGTAA
Protein Sequence
MLAAQQQQQPQQQHTAATATGGSTVALEDAGLERARRDSSTSESSLEHLDLSRTPKKLSSSSGAPQPTSTPHEATSRKRKLRQLQQPQQLLSDEDEQQQQQQQQQLLEQSAQRLRHKQRRSGNAAAVAAAASASIVVDYSASGDASSLRKKFRLNRSSASSINGNNGELSESGFVDGSAHSGYLLSASSAAQSASAAQQQQQQQQQQQQQLASSSSSGGSSPQGLYHSSAESGIGAGDEHMKYVCPICEVVSATPHEFTNHIRCHNYANGDTENFTCRICSKVLSSASSLDRHVLVHTGERPFNCRYCHLTFTTNGNMHRHMRTHKQHQTTQQQQQQQQQQTPQQQQTPQQQQTPQQHAPQQHGQQQRRQQHGGAAAGRAESYESDASCSTDVSSSSSSSDSSNSSNTNNNNNNNNNNSEQTNKNNNSNGEQQQLLLACKQRRPKTNINNNNILSDEEQPKQPKSEPDAEPEPEPELDSDDAESVDVAQMITSTPDVATLLATGDGGDGDGSTRSSPSPGLQSCPACNTGEFETLPALCAHLDAAHPDIPAKCRDCDVIFASHRQLQAHSCRGQLQLPPLLGASSSPLHKLEMVDHDQEQEQEQQYANEEDEEELAHGEQLASSEQRDEFFQQLYLKGKAGGLPSPIKRELSEQRLEQRQDRQDLADIQSILHMTSSSCTSSFLRNFEQSVNTPCSSQYSLDGRDGEEEAQDAFTSEFRRMKLRGEFPCKLCSAVFPNLRALKGHNRVHLAAVGAAGPFRCNMCPYAVCDKAALVRHMRTHNGDRPYECAVCNYAFTTKANCERHLRNRHGKTSREEVKRAIVYHPAEDASCEEGNKRPTTGQDTDLAELSYRSLSPPPPPAPLPPLPTASHESQLKHMLLAEPCAKLPPPPPPPTTTATPLKIQVKSLDQLVEKPLAPPAMDLSMDVLDLSKKPTQQLERQREREREQEHDLLLLQQQQQQLQQQVQQQVQQQVQQQQLFSAGDATTQYMQQLLRNLMFQQTPGFSFFGYMAPPTTTTTATSAEKSTQPGTNPGQTPATVAAGMPMGMPVPVTVPVPAGGPVKMVIKNGVLMPKQKQRRYRTERPFACEHCSARFTLRSNMERHVKQQHPQYYAQRQRSGHHVMRGRAASSNAAAAAAAAAAAAAAAAAAAAMSNLAQQQQQQHAHPPISEQVKYAILAQQLKARKDTDLLHQALAHGSSSALLHFNYNNNSNNNSNSNNNNKQQQPPHPINGAAAADDDEPPKLIIDEDDEAEEEEEFDDTEEEHEEEEELEMEEDADEEQPIAQLDQLELPAAAAATTATQPRPGTPIEAAKKVAESILEQVIKAQAKPDPESDAVAMPTPTTTSTATPTPGPTTMKTMIAQAESVAKSLKDVASSPFKDESQDLVPVAKLVDNATSNQVSFNSYFRPSDVANHMEQSDEEGLVASGSASESNNSGTEDVTSSSCNEPKKKSAYSLAPNRVSCPYCQRMFPWSSSLRRHILTHTGQKPFKCSHCPLLFTTKSNCDRHLLRKHGNVESAMSVYVPTEDVSEPIPVPKSVEEIALEEQRRRKAAEAERERERQLELERERERERDRKIEREREQQQQQQLIQQLAAAQLRQQLTNAAAAAAAAAAAAAAASAAGAGVGGGAGNSPTAGGEGSNGSELPYKCHLCEFSFGERLQCLEHIKQLHGQEFALLLAKGAIETETLHDHQQQQQQQPSSNPATAAAAAGSEDESLAPSGRGNGKYPDYSNRKVICAFCVRRFWSTEDLRRHMRTHSGERPFQCEICLRKFTLKHSMLRHMKKHSGRSHNGEQGASDCSDDEQMATPPGTPTPTPMAMPTPSSNNNNNNNNSSTCQNNNNNNSKQSLRLDKTPDWRLQKDKIGDATPTATAAAFGMASGDLIGNLLGISDQGILNKLLSSADEAAKLLGVEK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00563368;
90% Identity
-
80% Identity
-