Basic Information

Insect: Drosophila borealis
Gene Symbol: -
Assembly: GCA_035045885.1
Location: JAWNOR010000299.1:1270165-1273997[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 13 4.6 3.7e+02 2.2 1.1 1 23 174 200 174 200 0.76

2 13 0.00059 0.048 14.4 0.4 1 23 206 229 206 229 0.96

3 13 0.00041 0.033 14.9 4.6 1 23 234 257 234 257 0.96

4 13 0.00033 0.027 15.3 4.6 1 23 262 284 262 284 0.98

5 13 5.6 4.6e+02 1.9 5.7 2 23 291 314 290 314 0.90

6 13 0.00049 0.04 14.7 1.0 3 23 324 345 323 345 0.95

7 13 0.027 2.2 9.2 0.3 1 23 351 374 351 374 0.95

8 13 0.34 27 5.8 0.2 5 23 390 409 385 409 0.87

9 13 3.1e-05 0.0025 18.5 0.4 1 23 438 460 438 460 0.98

10 13 2.9e-06 0.00023 21.7 4.2 1 23 466 488 466 488 0.97

11 13 9.1e-06 0.00074 20.2 0.1 2 23 495 516 495 516 0.97

12 13 0.0012 0.1 13.4 0.9 1 23 523 545 523 545 0.99

13 13 0.0008 0.065 14.0 5.0 1 23 551 574 551 574 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	13	4.6	3.7e+02	2.2	1.1	1	23	174	200	174	200	0.76
2	13	0.00059	0.048	14.4	0.4	1	23	206	229	206	229	0.96
3	13	0.00041	0.033	14.9	4.6	1	23	234	257	234	257	0.96
4	13	0.00033	0.027	15.3	4.6	1	23	262	284	262	284	0.98
5	13	5.6	4.6e+02	1.9	5.7	2	23	291	314	290	314	0.90
6	13	0.00049	0.04	14.7	1.0	3	23	324	345	323	345	0.95
7	13	0.027	2.2	9.2	0.3	1	23	351	374	351	374	0.95
8	13	0.34	27	5.8	0.2	5	23	390	409	385	409	0.87
9	13	3.1e-05	0.0025	18.5	0.4	1	23	438	460	438	460	0.98
10	13	2.9e-06	0.00023	21.7	4.2	1	23	466	488	466	488	0.97
11	13	9.1e-06	0.00074	20.2	0.1	2	23	495	516	495	516	0.97
12	13	0.0012	0.1	13.4	0.9	1	23	523	545	523	545	0.99
13	13	0.0008	0.065	14.0	5.0	1	23	551	574	551	574	0.98

Sequence Information

Coding Sequence: ATGGAAACGTGTCGCACTTGTGCAAGGTGCGATTTCGAAAATGGCAACAACTATTGGCTGGACATGTTCCATCCAACGCGTTGGCAGAGCGAGATGGCGCAAATACGCCTGGAGTTTGTCAACTGGAAGTTACAGATCTCACCAAACGATGGACTGCCCCAAAAAATTTGCAGCGATTGCTTTACAAAATTCTGCTCCATATACACATTTCGCATGGCCTGCCAGGACGCACAGTTAAAGTTGTcgaatatttttgataaaatcGATGCGAATTCGCTCTATGATAAAAACGACGAGGACAATATTGAGGAGGCTGTGGATGAAATAGAAGCGGCGACCGAaatagaaacagaaacagaaacaacgacaacaacacaaaatacTGCCATTATTGAGGCCAACACGCAAACAACACCCATAGAAATCTTTGTGGAAACGATTAGCATCAACGAATCTGAATCCCTACAACCAGATGAGAAAACCGATTTAGCTTCAGATTACAGCACATTAAACATAAGCTATGCTTGTAAATTTTGTCATAAACCGCAGGAAAGCTATGAGCTGCAGCACCTATTACTAGAGCACATCAGTAACGCACACGATCCGGATCAGCCCTACAACTGTCCGGAGTGCACAGAGTGCTTCCAAGATGCCGCATCACGTACCGTGCACATGAAGGGCGTGCATGTGGTAAAGCATCACACCTGTGAGGTGTGCGGCAAAAAGTACGGAGATCGTCATAATCTCGACCatcatattgaaaaatatcatTCGGAAACGGATTTCGAGTGCAGCATGTGCGAGAAACGTTTCTTTACGCGCAAAAGCCTGCACTATCACATGAACTGGCACAATCCGGAGCGGCAGCTCCGATGTCGCCACAGCGGCTGCGACAGGCTGTTTATCAACCAAAGACATCTCAAGTGTCACGAGGCAACGCACTCAACGGGCTCCCGTAAGAGCGAATACTGCGGCTTCTGTGGTAAAGCTTTCATACACGTTAAAACTCTACGTTGGCATATCTATCGACAGCACGGCGGGGAGAAGCCTTTCAAATGCGCCAACTGCTCTGAGGTTTTTGGCTCCTATGCGGAGAAGCGCTTACACATGCTCGAGCAGCACAGGGCGAATCTGACGCATCAGGAGCGCAGCGAATGCATGTTTCAGTCCTGTCGCCAGGAGTTCGACACCGAACAGGAGCTCATCCAGCACATGAGCGCCGAACATGTGCAGCGCGAACCCTCCACACCGATAATTGCGAACAATAAACGCGTGCTCCAGTGCAAACGGGAGCGTCAGTATACGGGACTCTTCCAGTGCGGCAGCTGTACGCAACGTTTCAACATGAAGTCCGCCCTGGAGCGGCACATGGCTGTCCATTCCGCTGACCGGCTGCACGCCTGCCCGCACTGCTCCAAGCGGTATAAGCGCGCCCAGGACCTGAAGTGGCACATGAAGACGCATGCCAATGAGAAGCCCAATGTCTGCGATGTCTGCGGCAAGGCGTTTGCTTTGAAATATGTGCTCACCCAGCATATGCGCAGTCATGAGGTTCTGGAGAAGAACTTCAAATGCGAGACCTGCGGACGGGCCTATCTGTTTGAGAAGTCTCTGCGTCTGCATCAACGCGTTCACACGGGGAACACCTACTACAAGTGCGATCTGTGCCAGGAGCGCTTTGTCACTCAcatcaaatttaaaaCTCATATGAAAAAGACACATGATAGCAATCAGTCGCATGCCAAAGATACGCTGGATGATTTGATCAACATTGTGATTTCCTGA
Protein Sequence: METCRTCARCDFENGNNYWLDMFHPTRWQSEMAQIRLEFVNWKLQISPNDGLPQKICSDCFTKFCSIYTFRMACQDAQLKLSNIFDKIDANSLYDKNDEDNIEEAVDEIEAATEIETETETTTTTQNTAIIEANTQTTPIEIFVETISINESESLQPDEKTDLASDYSTLNISYACKFCHKPQESYELQHLLLEHISNAHDPDQPYNCPECTECFQDAASRTVHMKGVHVVKHHTCEVCGKKYGDRHNLDHHIEKYHSETDFECSMCEKRFFTRKSLHYHMNWHNPERQLRCRHSGCDRLFINQRHLKCHEATHSTGSRKSEYCGFCGKAFIHVKTLRWHIYRQHGGEKPFKCANCSEVFGSYAEKRLHMLEQHRANLTHQERSECMFQSCRQEFDTEQELIQHMSAEHVQREPSTPIIANNKRVLQCKRERQYTGLFQCGSCTQRFNMKSALERHMAVHSADRLHACPHCSKRYKRAQDLKWHMKTHANEKPNVCDVCGKAFALKYVLTQHMRSHEVLEKNFKCETCGRAYLFEKSLRLHQRVHTGNTYYKCDLCQERFVTHIKFKTHMKKTHDSNQSHAKDTLDDLINIVIS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00502704;
90% Identity: iTF_00531129;
80% Identity: -