Dboq003168.1
Basic Information
- Insect
- Drosophila bocqueti
- Gene Symbol
- LITAF
- Assembly
- GCA_018151655.1
- Location
- JAECXF010000057.1:18148226-18149966[+]
Transcription Factor Domain
- TF Family
- zf-LITAF-like
- Domain
- zf-LITAF-like domain
- PFAM
- PF10601
- TF Group
- Zinc-Coordinating Group
- Description
- Members of this family display a conserved zinc ribbon structure [3] with the motif C-XX-C- separated from the more C-terminal HX-C(P)X-C-X4-G-R motif by a variable region of usually 25-30 (hydrophobic) residues. Although it belongs to one of the zinc finger's fold groups (zinc ribbon), this particular domain was first identified in LPS-induced tumour necrosis alpha factor (LITAF) which is produced in mammalian cells after being challenged with lipopolysaccharide (LPS)[2]. The hydrophobic region probably inserts into the membrane rather than traversing it. Such an insertion brings together the N- and C-terminal C-XX-C motifs to form a compact Zn2+-binding structure [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 2 1.9 2.1e+03 -1.1 0.1 46 56 2 12 1 22 0.75 2 2 2.6e-22 2.8e-19 69.0 18.2 3 69 72 138 70 139 0.96
Sequence Information
- Coding Sequence
- ATGCCATATTTCAACGAAAACTGTAAAACTGTGGCCGCCGATTTTAGTGCCTGTCCCGCCGCAAACATGAACACCACATGGGTGGGCACTGCTCCGCATACGGACACGGAAACGTCGCCGCCGCCGAACTACGGCGTGGTGGTGACCCAGATACCTGTTTACACCCTGAACGGAGTGGGGACGGGGGCAATACCCTTGACAGTTGGCTGGAAGAAAATGCGGGTGCGGTGTCCGTCCTGCAAGGGGGAGGTGGACACTAATCTGCAGACCTCGCCCACCCGGAAGACCCACCTGTGCGCCCTGACCTTGTATATCTGCTGTTGCTGGCCTTTTGTATGTTTGCCGTACCTCTTCAATTACTGCAAGAATGTCCAGCACTATTGTCCCAATTGTGGGTGCCATATAGGAACTTACACCATTTGA
- Protein Sequence
- MPYFNENCKTVAADFSACPAANMNTTWVGTAPHTDTETSPPPNYGVVVTQIPVYTLNGVGTGAIPLTVGWKKMRVRCPSCKGEVDTNLQTSPTRKTHLCALTLYICCCWPFVCLPYLFNYCKNVQHYCPNCGCHIGTYTI
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00613860;
- 90% Identity
- -
- 80% Identity
- -