Dboq006073.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Drosophila bocqueti
Gene Symbol
kel
Assembly
GCA_018151655.1
Location
JAECXF010000002.1:15550920-15559404[+]

Transcription Factor Domain

TF Family
BTB
Domain
zf-C2H2|ZBTB
PFAM
PF00651
TF Group
Zinc-Coordinating Group
Description
The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 1 1.7e-36 5.3e-34 116.7 1.7 1 109 149 254 149 255 0.97

Sequence Information

Coding Sequence
ATGATAGCTCTGAGTGCGCTTTTAACNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNGCGGGCGGTGAGCTGTTTGTGGCTCCGCCGCCCGGCCTGGGCGTCGCTGTGGGCGTGGCAGCCATGCAACAGCGCAATCGGTTGCTGCAGCAACAACAGCACCACCAGCAGCAGCAGCAGCCACAGAATCCCGCCGCCGAGGGCAGTGGCCTGGACCGCGGCAGCTGTCTTTTGCGCTATGCCAGCCAGAATTCACTGGACGAGAGCAGCCAGAAGCACGTCCAGCGGCCGAATGGCAAGGAGCGCGGCACCGTGGGACAGTACAGCAATGAGCAGCACACGGCGCGATCCTTTGATGCCATGAACGAGATGCGCAAACAAAAACAACTCTGTGATGTGATATTAGTGGCCGACGATGTGGAAATCCATGCCCATCGCATGGTTCTGGCCTCCTGCAGTCCGTATTTCTATGCAATGTTCACCGGATTCGAGGAGTCGCGTCAGACGCGGATCACCCTACAAAGTGTCGATGCTCGGGCACTGGAACTGCTCATTGATTATGTGTACACAGCCACCGTGGAGGTAAACGAGGATAATGTGCAGGTCCTGCTGACGGCCGCCAATCTCCTGCAGCTCAACGATGTGCGCGATGCCTGCTGCGATTTCCTGCAGACCCAGCTGGATGCCAGTAATTGCCTGGGCATCCGGGAATTTGCCGATCTTCATGCCTGCGTGGAATTATTGAACTACGCGGAGACCTACATCGAACAGCATTTCAACGAGGTGATCCAGTTCGATGAGTTTCTGAATCTGTCGCACGAGCAGGTCATCAGCTTAATAGGCAACGACCGGATCTCGGTGCCGAACGAGGAGCGTGTGTACGAGTGTGTCATTGCCTGGCTCCGCTACGATGTCCCCATGCGCGAGCAGTTCACCTCCTCGCTCATGGAGCACGTCCGTCTGCCCTTCCTGTCCAAGGAGTACATCACACAGCGCGTGGACAAGGAGCTACTGCTCGAGGGCAACATCATCTGCAAGAATCTGATAATCGAGGCATTGACCTATCATCTGCTGCCCACGGAAACGAAATCGGCGAGAACTGTGCCCCGGAAACCGGTGGGAATGCCCAAAATCCTGCTCGTCATTGGCGGGCAGGCGCCCAAGGCCATTCGGTCGGTGGAATGGTATGATTTGAGGGAGGAGAAGTGGTATCAGGCCGCCGAAATGCCAAACAGGCGGTGTCGTTCCGGACTGAGTGTTCTGGGGGAGAAAGTCTATGCCGTTGGTGGCTTCAATGGCTCGCTGCGCGTTCGCACTGTGGATGTCTATGATCCGACCACGGATCAATGGGCCAACTGCTGCAACATGGAAGCACGGCGATCCACACTGGGCGTAGCTGTCCTAAACGGTTGCATCTACGCCGTGGGCGGATTCGATGGCACCACCGGGCTCTCCAGTGCCGAGATGTATGATCCCAAGACTGACATTTGGCGCTTCATCGCCTCCATGTCCACGCGTCGCAGCTCAGTGGGAGTGGGCGTGGTCCATGGTCTCCTCTATGCCGTTGGCGGCTACGATGGCTTCTCGCGCCAATGCCTGTCGTCGGTGGAACGCTACAATCCCGATACGGACACCTGGGTAGCGGTGGCCGAGATGAGTTCTAGGCGCAGTGGCGCCGGTGTCGGCGTTCTCAATAATATCCTGTATGCCGTGGGCGGACACGATGGCCCAATGGTGAGGAAATCCGTGGAGGCCTACGACTGTGAAACGAACTCATGGCGCTCGGTGGCGGATATGTCTTACTGCCGGCGCAATGCCGGCGTTGTCGCGCACGAAGGTCTGCTCTATGTGGTTGGAGGCGATGATGGCACCACAAATCTCGCCTCGGTTGAGGTCTATTGTCCCGATTCGGACAGCTGGAGGATGCTGCCGGCCCTGATGACCATCGGACGCAAGCAGGGTGCATTGGCACGTCAAGCGGCTTCGCTGGCCATCGCACTGCTGCAGGATGATGAGAATAGTCAGGCTGAGGGCACAATGGAGGGCGGCGCCATTGGTGGTGCTGCTGCTGCCATCTATGGCAATCTGGCGCCAGTTGGAGCAGCTGCTGCACCGCCAGCAGCAGCTCCTGCTCCTGCGCCAGCTGCTGCTGCCGCTTCAGCTGCTGCTCCACAGCCAAATCATCCGCACTACGAGAACATCTATGCACCAATTGGTCAGCCCAGCAATCAAGCGGCTGCTGCCAATGCCCCTGCAAATGCTGAAGAAGCTCAGCAACCACAACCACAACAACAACCAGCACCAACGGAAGCCAATGCCAGTAATAACAACAACAACAACCAGTCACCGCCAATAGCACAACCACAACAAGCACAGCCACAGCCACAACAGCCACAGCCACAACGAATACTGCCCATGAACAACTACAGAAATGACTTGTACGATCGATCTGGGGGAGGAATCTTAGGATCAAACGCTTCTGCCGCCTCCGCCGGCGCCTATGATGTGCCAAGAGCCGTGAGATCTGGCCTCGGTTATAGGCGTAACTTTCGCATCGATATGCAGAATGGCAATCGCTATGGCAATGGCCTTCGCTGCACTCCCCTCTACACCACCAACAGTCGCTCCAATTGCCAGCGACAGCGCAGCTTTGATGACACCGAGTCCACCGATGGCTACAATCTCCCCTATGCCGCCGGCGCTGGTGCCATGCGCTATGAGAACATTTACGAGCAGATACGAGATGAACCGCTTTATCGCACCTCCGCTGCCGCCGCCGCTAATCGTGTGCCGCTCTATACACGGCTCGATGTTCTGGGCCATGGCATTGGCAGGATTGAGAGACACTTGAGCTCGTCGTGTGGCAACATCGATCACTATAATCTGGGTGGTCACTATGCCGTGCTGGGACACTCGCATTTCGGTACAGTGGGTCACATACGTTTAAATGCTAATGGAACAGGCGGCGGCGGCGGAGGAGGAGCTGCTGTAACCAATGGAAGTACCACCTGCAATGTGCCAAATTGCCAGGCGTACATAGGGAATGCCGCCGGCTCATCGGCGCCCGTGGAGTATGCCAATGTCAAAGTTCCGGTAAAGAACAGCGCCTCTAGCTTCTTTAGCTGCCTGCATGGCGAGAATTCTCAGAGTATGACGAATATATACAAAACATCGGGTGCCACAGCACCCACTCACCACTCTCCCCTAACGCCCAATGTGTCCATGGAGCGAGCAGCTCGATCAGCATCCGCTGGAGCTGCAGGAGTCTCGGTTGTCCCAGTTGAGGAGCCACCTTTAGCGGATAATCAGCCAAGTTCATCGAATAGCACCACGAGTCGACCGCCAACGGGAGCTATACCCAAAGTAAAGATTGCCCCCACCAGCAAGGCACCCAAAGAAGCCACAACTGGAGGTGCATCATCATCAGGCACTGCTACCCCCTCCTCATCAGGTGCAACGGACAAGAGTTCATCGACGTCTGGTGCAGGAGCACCAGGCAAGGCGGCAGGAACTTTGGCCAAGAAAAGCTCAACGGGAGCAGCAGCAGCTTCGGCACGCACCACCACCAGTTCATCCGGCGATGGCGCCCTAAATCGCATCTCCAAGTCAAGTCTCCAGTGGCTGCTGGTGAACAAGTGGCTTCCTTTGTGGATTGGCCAAGGGCCAGATTGCAAGGTAATCGACTTTAACTTTATGTTTTCCCGCGATTGTGTCAGCTGCGACACCGCCTCGGTGGCCTCGCAGATGTCAAATCCGTATGGAACTCCACGTTTGGGTGTCGGTCTACCCCAGGATATGGTGCGCTTCCAGAGCTCCTGCGCAGGTGGAGCTTGCACGGCAGCAGCTGGAGGAGGTGGTGCTGCAACCATGCGAAGGGATGCCACAGGTCGACCCCTGCACAGCACCTTGAGTCGTCTGAGGATGAATGGAGGGGAGAGAAGGAACCAGAATGCAGTGGCGGCTGCCAACTATCGTTACGAAGATCCCTCGTACGAGAATGTCCATGTTCAGTGGCAGAATGGCTTCGAGTTTGGCAGATCCCGTGACTACGATCCGAATCCCATTTNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNCCATGCTCCAGAGAGCCAGATCGGAGAGTCCCACGTTCAGCAACCAGCAGAGGCGCCTCCAGCGTCAGGCCGCTCAGGCAGCCCAAGCTCAATTGAAGCCGCCGCCGCCAGGATCACCAGATCCCTTCAAGAATTACAAACTAAATGCGGAGAATAACAGCTTCAAGCCTAAGACAGCGGCGGCTGCTGAGGAGCTGGAAGGAGCTGTAGGAGGAGCTGCAGGAGGTGCTGTGGGAGGAGCTGCAGGAGGAGTTGTAGGAGGAGCTGCAGGAGGAGCTGCAGGAGGAGCTGTAGGGGGAGCTGCAGGAGGTGCTGCAGGAGGAGCTGCAGGAGGAGCTGTGGTGGAAATGCCTCCTCTGGAGCTGGAGGCCGAGTCCGTGGATCCTGTGAACTTGAGTGATAATGAGTCAGAGGCCATTGGTGGCCAAAGTAATACTTCGAACAGCACAAACAGCCATGCGAATGAGCAAAATGATTAA
Protein Sequence
MIALSALLTXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXAGGELFVAPPPGLGVAVGVAAMQQRNRLLQQQQHHQQQQQPQNPAAEGSGLDRGSCLLRYASQNSLDESSQKHVQRPNGKERGTVGQYSNEQHTARSFDAMNEMRKQKQLCDVILVADDVEIHAHRMVLASCSPYFYAMFTGFEESRQTRITLQSVDARALELLIDYVYTATVEVNEDNVQVLLTAANLLQLNDVRDACCDFLQTQLDASNCLGIREFADLHACVELLNYAETYIEQHFNEVIQFDEFLNLSHEQVISLIGNDRISVPNEERVYECVIAWLRYDVPMREQFTSSLMEHVRLPFLSKEYITQRVDKELLLEGNIICKNLIIEALTYHLLPTETKSARTVPRKPVGMPKILLVIGGQAPKAIRSVEWYDLREEKWYQAAEMPNRRCRSGLSVLGEKVYAVGGFNGSLRVRTVDVYDPTTDQWANCCNMEARRSTLGVAVLNGCIYAVGGFDGTTGLSSAEMYDPKTDIWRFIASMSTRRSSVGVGVVHGLLYAVGGYDGFSRQCLSSVERYNPDTDTWVAVAEMSSRRSGAGVGVLNNILYAVGGHDGPMVRKSVEAYDCETNSWRSVADMSYCRRNAGVVAHEGLLYVVGGDDGTTNLASVEVYCPDSDSWRMLPALMTIGRKQGALARQAASLAIALLQDDENSQAEGTMEGGAIGGAAAAIYGNLAPVGAAAAPPAAAPAPAPAAAAASAAAPQPNHPHYENIYAPIGQPSNQAAAANAPANAEEAQQPQPQQQPAPTEANASNNNNNNQSPPIAQPQQAQPQPQQPQPQRILPMNNYRNDLYDRSGGGILGSNASAASAGAYDVPRAVRSGLGYRRNFRIDMQNGNRYGNGLRCTPLYTTNSRSNCQRQRSFDDTESTDGYNLPYAAGAGAMRYENIYEQIRDEPLYRTSAAAAANRVPLYTRLDVLGHGIGRIERHLSSSCGNIDHYNLGGHYAVLGHSHFGTVGHIRLNANGTGGGGGGGAAVTNGSTTCNVPNCQAYIGNAAGSSAPVEYANVKVPVKNSASSFFSCLHGENSQSMTNIYKTSGATAPTHHSPLTPNVSMERAARSASAGAAGVSVVPVEEPPLADNQPSSSNSTTSRPPTGAIPKVKIAPTSKAPKEATTGGASSSGTATPSSSGATDKSSSTSGAGAPGKAAGTLAKKSSTGAAAASARTTTSSSGDGALNRISKSSLQWLLVNKWLPLWIGQGPDCKVIDFNFMFSRDCVSCDTASVASQMSNPYGTPRLGVGLPQDMVRFQSSCAGGACTAAAGGGGAATMRRDATGRPLHSTLSRLRMNGGERRNQNAVAAANYRYEDPSYENVHVQWQNGFEFGRSRDYDPNPIXXXXXXXXXXXXXMLQRARSESPTFSNQQRRLQRQAAQAAQAQLKPPPPGSPDPFKNYKLNAENNSFKPKTAAAAEELEGAVGGAAGGAVGGAAGGVVGGAAGGAAGGAVGGAAGGAAGGAAGGAVVEMPPLELEAESVDPVNLSDNESEAIGGQSNTSNSTNSHANEQND

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00480225; iTF_00531713; iTF_00492290; iTF_00612868; iTF_00541129; iTF_00617705; iTF_00571953; iTF_00489427; iTF_00590293; iTF_00483037; iTF_00533149; iTF_00527358; iTF_00613579; iTF_00488719; iTF_00524468;
90% Identity
iTF_00617705;
80% Identity
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