Dbir003055.1
Basic Information
- Insect
- Drosophila birchii
- Gene Symbol
- -
- Assembly
- GCA_008042755.1
- Location
- VNKA01006430.1:330297-331483[-]
Transcription Factor Domain
- TF Family
- zf-LITAF-like
- Domain
- zf-LITAF-like domain
- PFAM
- PF10601
- TF Group
- Zinc-Coordinating Group
- Description
- Members of this family display a conserved zinc ribbon structure [3] with the motif C-XX-C- separated from the more C-terminal HX-C(P)X-C-X4-G-R motif by a variable region of usually 25-30 (hydrophobic) residues. Although it belongs to one of the zinc finger's fold groups (zinc ribbon), this particular domain was first identified in LPS-induced tumour necrosis alpha factor (LITAF) which is produced in mammalian cells after being challenged with lipopolysaccharide (LPS)[2]. The hydrophobic region probably inserts into the membrane rather than traversing it. Such an insertion brings together the N- and C-terminal C-XX-C motifs to form a compact Zn2+-binding structure [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 1 9.2e-27 9.1e-24 83.5 14.2 1 70 81 150 81 150 0.96
Sequence Information
- Coding Sequence
- ATGGAAAAAGTGTATCCGGCTGCACCTTTGGAGGCGCCCAAGGGCTCTGGAGATGTGGAGGCCACCTACGTCTCGCCGGAGCATCAGCAGCTGTTGACGACACCACCGGCACCGCCGAGCTATGACCAGGCCACAGCTACACCGGCAGAAACCACGGGACCCGGGCAAGGAGTTACTCCAGCAACCACCACTACAACCACCCACCACACAGTGGTGGTGGTACCCAGTTCGCCCTACGGCCCAGAGCCCATGGATATCCAGTGTCCGTATTGCCACAACCATGTCCGGACCCGGATCTCCTACAAGCCCAACTCTCGCACCCATCTGATAGCCTTGATTCTGTGCCTCTTCCAGTTGTACTGCTGCGTGTGCCTGCCGTACTGCATTTCCAGTTGCATGAACACGAATCACTACTGTGGCATGTGCGATCGTTACCTGGGCACATACAACCGCAAGTGA
- Protein Sequence
- MEKVYPAAPLEAPKGSGDVEATYVSPEHQQLLTTPPAPPSYDQATATPAETTGPGQGVTPATTTTTTHHTVVVVPSSPYGPEPMDIQCPYCHNHVRTRISYKPNSRTHLIALILCLFQLYCCVCLPYCISSCMNTNHYCGMCDRYLGTYNRK
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00504356;
- 90% Identity
- iTF_00541447; iTF_00478382; iTF_00594914; iTF_00491887; iTF_00562127; iTF_00490449; iTF_00492629; iTF_00485527; iTF_00570063; iTF_00526245; iTF_00489748; iTF_00613174; iTF_00527708; iTF_00524787; iTF_00594212; iTF_00618005; iTF_00533465;
- 80% Identity
- -