Basic Information

Insect: Drosophila birchii
Gene Symbol: ken1
Assembly: GCA_008042755.1
Location: VNKA01005462.1:508410-510564[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.001 0.083 13.5 2.0 2 23 194 215 193 215 0.97

2 12 0.0095 0.76 10.4 0.1 1 23 221 246 221 246 0.90

3 12 0.011 0.87 10.3 0.1 3 23 255 278 253 278 0.93

4 12 0.00091 0.073 13.6 0.4 2 23 291 312 290 312 0.96

5 12 8.9e-06 0.00072 20.0 0.6 1 23 319 341 319 341 0.98

6 12 0.0085 0.69 10.6 0.2 1 23 347 369 347 369 0.98

7 12 0.014 1.2 9.9 4.0 1 23 375 398 375 398 0.97

8 12 0.0095 0.77 10.4 4.0 1 23 404 426 404 426 0.96

9 12 0.00081 0.065 13.8 2.9 2 23 433 454 432 454 0.96

10 12 0.00026 0.021 15.3 1.1 3 23 543 564 541 564 0.95

11 12 0.01 0.82 10.3 0.7 1 19 570 588 570 592 0.95

12 12 9.3e-06 0.00075 19.9 1.2 1 23 598 620 598 620 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.001	0.083	13.5	2.0	2	23	194	215	193	215	0.97
2	12	0.0095	0.76	10.4	0.1	1	23	221	246	221	246	0.90
3	12	0.011	0.87	10.3	0.1	3	23	255	278	253	278	0.93
4	12	0.00091	0.073	13.6	0.4	2	23	291	312	290	312	0.96
5	12	8.9e-06	0.00072	20.0	0.6	1	23	319	341	319	341	0.98
6	12	0.0085	0.69	10.6	0.2	1	23	347	369	347	369	0.98
7	12	0.014	1.2	9.9	4.0	1	23	375	398	375	398	0.97
8	12	0.0095	0.77	10.4	4.0	1	23	404	426	404	426	0.96
9	12	0.00081	0.065	13.8	2.9	2	23	433	454	432	454	0.96
10	12	0.00026	0.021	15.3	1.1	3	23	543	564	541	564	0.95
11	12	0.01	0.82	10.3	0.7	1	19	570	588	570	592	0.95
12	12	9.3e-06	0.00075	19.9	1.2	1	23	598	620	598	620	0.98

Sequence Information

Coding Sequence: ATGGGCACCAAGGATCTCCAGTATTCCGTCCACGCACTGTGCCGCACCTGTCTGATGCACCTGGAGCAGGGGATAGGTCACGACCTGTTCCTGATCCCAGATCTGGCCAAGAAACTGACTGTTTGTACGTCAATAAAGGTGGACGCGCAGGATGGCTTTCCACGCCATATCTGCTACCAGTGCTTGGGGAAGTTGAACGAGCTTCACGATTTCCAGGAGCAGTGTGCGGGTTCCCAAAAGCGACTCAAGGAGATGGTGGCCAACAGCCAGGCGCTTCCAGTTGCACAGTTTGAGCCTGTGGCGGAGGAAACTGACACGCTGGGCAGGCAAGAGGAGCAGGCCAGTTATGATCCTCTCCTTAACCACAAACTGGAGATGATTGACAACGAAGAGGAGGTGTTTAAGATGCTGGAAACGGTGGACAGGGAACCGGAGGAGCATAACCAAGAGGATTCCTCAGGCGAAGAGCATGAACAGGATGGGCAGGAGGCGCAGAAGAGCTTCTCCAGCGACGACGAACAACCCTTGGCAACGCGGAGAAAAACATCCTGCGCCAAGCGTCGCTCGCATCACCTTATCACCTGTCCCATCTGCCAGCAGAAGTTCAAGAAGCCGTTGAAGTACGAGGAGCACATGAAGCACCACAACGACCTGCTGCCCTTTCAGTGCGCGGAAGACAGCTGCCGGAAAGGCTTCACCACGCCAGGTGCTCTCCGGCTGCACGTAGACTACGCGCACACCAATAAGACGGATGAGATTCCGTGTACAGTGGAGGGCTGCCGCTTGATGTTTCCTCGCCTCCGCCTGCTGACGATCCACCTGAAAAAGGTGCACAACCAGGCCAGGGTGAGTGCTCCGCGGGCGGAGCAGCCGTGTGGGGAGTGCGGCCTCGTCTTCCGCTGTCCGGTGGCCCTCAAGAAGCACATGTACAAGCACACTGGCGAGGAGCTGCCGTATCCCTGCAACATATGCGGCAAGGGCTTCCACATCAACAGCGCCCTGAAGAATCATCTCCTACGGCACGCGGGCATCAAGAACTACGTGTGTCCCTACTGCGGCGTGGGCAAGACCACAAGGCAGGAATGGAGCAAGCACCTCCTCACGCACACCCAGGAGAAGCAGTTCAAGTGCCACATCTGCGACCATGCCACCCACACGAAGCGCGCCTTGGACAGCCACGTAAAGATTGTGCACGAGAAGATCCGGAACTTTGCCTGCCAGTACTGTGGGAAGACCTTCGGCAAGTCCCATGCCTGCAAGATCCATGAGATGACGCACACTGGGGAGAAGCGGTGCGAGTGCAAGGTCTGCGGCAAGAAGTTCCTGTACACGGAGAGCCTGACAAAGCATCTCAAGATCCACGAAAAGAGCGTGGAGAGAGCTCTGGAAACGTATCGCCAAAGGCAGGGCGACTGTGAACCCGGAGAAGTACAAGTGGATGCGGATCAACTGCTAAAGGTGTGCGCCGAATCGGTGGCCACCATACCCAAAGACCCGCGTCGCGTGGAGCGAGTTGATCTGTCGCAACTGGCGGGCACAGTGGTGAATCCCATTCCCACTGTTCAACTGCCGCCCAGCGAGGCGTCGGTCCGCACGAAGTTCGTCCAGAAGGAGGGCATGCACCTTTGTCCCGGCTGCAGCCAGGGATTCAATAACCTCGGCAACATGAAGCGTCACTACAAGAGCGTCCACGAAAAGGTTAAGGACTTTGAGTGCCGCTTCTGCGCGCGCCGTTTCGCCAACTCACAGTCTCTGAAGCAACACGAGTGGATACATACCGGTGAGAAGCCGTACGAGTGCAAGGTGTGCAGTACCCACTTCCGCCAGGAGGCGGCTCTCATACGCCACCAGAAGGTCCATTACGAAAAGCCACCCAAGCCGCCGAAACCACCAAAGGAAATCACGGATAAGGCGCGACAAAAGGCGATGCAGAAGAATGAACGCCGGCAGAAGGTGGAGGCGATGCGACAGGAGATAGCCGCGGCTGCCAAGGAAGAGCTGAAGGATCTGGAGAAGCTACGGACCCTAGAGAAGCAACAGAACACCTATGAACAGTATCAGGCTGCAGCCAACCCGGAAACTGAGGAATCTTAA
Protein Sequence: MGTKDLQYSVHALCRTCLMHLEQGIGHDLFLIPDLAKKLTVCTSIKVDAQDGFPRHICYQCLGKLNELHDFQEQCAGSQKRLKEMVANSQALPVAQFEPVAEETDTLGRQEEQASYDPLLNHKLEMIDNEEEVFKMLETVDREPEEHNQEDSSGEEHEQDGQEAQKSFSSDDEQPLATRRKTSCAKRRSHHLITCPICQQKFKKPLKYEEHMKHHNDLLPFQCAEDSCRKGFTTPGALRLHVDYAHTNKTDEIPCTVEGCRLMFPRLRLLTIHLKKVHNQARVSAPRAEQPCGECGLVFRCPVALKKHMYKHTGEELPYPCNICGKGFHINSALKNHLLRHAGIKNYVCPYCGVGKTTRQEWSKHLLTHTQEKQFKCHICDHATHTKRALDSHVKIVHEKIRNFACQYCGKTFGKSHACKIHEMTHTGEKRCECKVCGKKFLYTESLTKHLKIHEKSVERALETYRQRQGDCEPGEVQVDADQLLKVCAESVATIPKDPRRVERVDLSQLAGTVVNPIPTVQLPPSEASVRTKFVQKEGMHLCPGCSQGFNNLGNMKRHYKSVHEKVKDFECRFCARRFANSQSLKQHEWIHTGEKPYECKVCSTHFRQEAALIRHQKVHYEKPPKPPKPPKEITDKARQKAMQKNERRQKVEAMRQEIAAAAKEELKDLEKLRTLEKQQNTYEQYQAAANPETEES

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00548237;
90% Identity: iTF_00524573;
80% Identity: -