Basic Information

Insect: Drosophila birchii
Gene Symbol: ZNF296
Assembly: GCA_008042755.1
Location: VNKA01005982.1:34647-39082[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 24 0.0015 0.12 13.0 1.2 1 23 209 231 209 231 0.96

2 24 2.3 1.9e+02 2.9 3.8 1 21 238 258 238 260 0.84

3 24 0.97 79 4.1 0.9 2 23 292 313 291 313 0.93

4 24 0.001 0.085 13.4 1.0 1 23 386 409 386 409 0.94

5 24 0.00098 0.079 13.5 0.1 2 23 484 505 483 505 0.96

6 24 0.00023 0.018 15.5 1.1 1 23 586 609 586 609 0.96

7 24 0.003 0.24 12.0 0.9 2 22 620 640 619 640 0.93

8 24 0.063 5.1 7.8 4.8 1 23 649 671 649 672 0.94

9 24 0.0024 0.2 12.3 1.5 2 23 693 714 692 714 0.97

10 24 3.6e-06 0.00029 21.2 5.2 1 23 721 743 721 743 0.99

11 24 0.0027 0.22 12.1 0.7 1 23 878 901 878 901 0.95

12 24 0.02 1.6 9.4 1.3 2 22 909 929 908 929 0.95

13 24 0.066 5.3 7.8 5.0 1 23 938 961 938 961 0.94

14 24 3.6e-05 0.0029 18.1 1.4 2 23 980 1001 979 1001 0.97

15 24 8.6e-05 0.0069 16.9 0.4 1 23 1008 1030 1008 1030 0.98

16 24 0.081 6.5 7.5 0.0 2 21 1057 1076 1056 1077 0.92

17 24 0.035 2.8 8.7 4.0 1 23 1123 1146 1123 1146 0.96

18 24 0.0045 0.37 11.4 0.9 1 23 1183 1206 1183 1206 0.96

19 24 0.00039 0.031 14.8 1.4 1 23 1233 1256 1233 1256 0.97

20 24 5e-06 0.00041 20.7 0.2 2 23 1283 1304 1282 1304 0.95

21 24 0.0026 0.21 12.2 2.6 1 23 1310 1332 1310 1332 0.99

22 24 2e-06 0.00016 22.0 2.0 1 23 1338 1360 1338 1360 0.97

23 24 1.7e-07 1.4e-05 25.3 2.4 1 23 1366 1388 1366 1388 0.99

24 24 0.00065 0.053 14.1 0.1 1 21 1394 1414 1394 1418 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	24	0.0015	0.12	13.0	1.2	1	23	209	231	209	231	0.96
2	24	2.3	1.9e+02	2.9	3.8	1	21	238	258	238	260	0.84
3	24	0.97	79	4.1	0.9	2	23	292	313	291	313	0.93
4	24	0.001	0.085	13.4	1.0	1	23	386	409	386	409	0.94
5	24	0.00098	0.079	13.5	0.1	2	23	484	505	483	505	0.96
6	24	0.00023	0.018	15.5	1.1	1	23	586	609	586	609	0.96
7	24	0.003	0.24	12.0	0.9	2	22	620	640	619	640	0.93
8	24	0.063	5.1	7.8	4.8	1	23	649	671	649	672	0.94
9	24	0.0024	0.2	12.3	1.5	2	23	693	714	692	714	0.97
10	24	3.6e-06	0.00029	21.2	5.2	1	23	721	743	721	743	0.99
11	24	0.0027	0.22	12.1	0.7	1	23	878	901	878	901	0.95
12	24	0.02	1.6	9.4	1.3	2	22	909	929	908	929	0.95
13	24	0.066	5.3	7.8	5.0	1	23	938	961	938	961	0.94
14	24	3.6e-05	0.0029	18.1	1.4	2	23	980	1001	979	1001	0.97
15	24	8.6e-05	0.0069	16.9	0.4	1	23	1008	1030	1008	1030	0.98
16	24	0.081	6.5	7.5	0.0	2	21	1057	1076	1056	1077	0.92
17	24	0.035	2.8	8.7	4.0	1	23	1123	1146	1123	1146	0.96
18	24	0.0045	0.37	11.4	0.9	1	23	1183	1206	1183	1206	0.96
19	24	0.00039	0.031	14.8	1.4	1	23	1233	1256	1233	1256	0.97
20	24	5e-06	0.00041	20.7	0.2	2	23	1283	1304	1282	1304	0.95
21	24	0.0026	0.21	12.2	2.6	1	23	1310	1332	1310	1332	0.99
22	24	2e-06	0.00016	22.0	2.0	1	23	1338	1360	1338	1360	0.97
23	24	1.7e-07	1.4e-05	25.3	2.4	1	23	1366	1388	1366	1388	0.99
24	24	0.00065	0.053	14.1	0.1	1	21	1394	1414	1394	1418	0.91

Sequence Information

Coding Sequence: ATGCTTCCCTCAAATATTTGCCGCACTTGTGCGGTCCAGAACACGGATTTGCGGCCATTGTCCACCTGTCTGGCCAGCGATGCCTCAAAAAGTTTCTATGATGCCCTTCAGGAGCTAACGCAAATCGATCCCCTGATTGAGAGCTCGAGCGACAGTCTGCCGCAGCATCTGTGCGGCGAATGCCTGAGGAGATTGGAAAGTGCTTACGCCTTTGTGGAACAGGCCAGAAAAGTGAATGGCGAGCTGTTGGTTCGGCTGCGGGAATGCCTTGACGAAATGCCCATTGACATTCCTCAAGAGCAGCCCATCAAAACCGAAGTAGATATCGATGAGGCGCCTCCCAAGTGTGTTGTGAATGTAGATTCTGCTGGAATATCTCCTGGGGAGTTCAAATGGCAGCCGGAAAGCGATAGCGATGGAGAATCTGCTGGAGCAGCATCCAGTGATGAGAATGAGGTCGAGAAGAAGCCCTACACTCTAAGACGCAGTGCGCGGAAAATTAAGCAGCCTGTTGAGAGTGATAATGAGGAGCCTGAGTTACCAACAGAACCATCGCCCAGCAAACGCCGCCGCGGCCGTCCGCCCGGCCCGGCCAAGCGCCAGTCGATGACCTCCGATGGACGCCATGCCTGCAATGTGTGCGGCAAGACCTTCTCCTGGTTCCGTGATATGCAGCGACATGCCCGCATTCATTTCGAGAAATCCAACGCTTTCGTTTGCGACACTTGCGGCAAGGGATTCCTGCGCAAGGACAAGTACACATTCCACCTGCGCTGCCACGAAAAACGCGATGCCAAATCCAAGGCTTTGCAGCTGGGGAACGAGTGGCTCTTCGCCGAACGGCTCTACAGTTCCGGCAGGCTGAAGAGAATCGAGTGCAAGCTGTGTGGCCTGAAGTGTTTGCGAATTCAGGAGCTCAGAAATCACTTGGTCAGCCATCAGGACGAGGAGAGCCTGCTCCAGTTGAGGGAGGATAGCGATGTTATCAAGGAGCATTATGCCGACCAGCTAGGCGACTTTGACGGCGTCAAGCAGCAAATTATCATGGACATAGCGGCGGGGCACTTGGAAAAGTTCGCTTCCATAGTCAATTTTCATGGCTACGAGTTAGGATTGTATGACTCGGACGAAGAATCTGCCAGCGAGGAGTCTAAATATGAATGCACGGTGTGCAATCTTCCCTTTGCGCGGAAACATCAAGTGGTGAGGCATACCCTGGAGAAGCACGCCCAATCCGCTTCTTCAGAGTTGCCCTGGCAACGTTGCGGCTCCTGTAAAGTCGGATTTCTCTGCTCCAGACTCTACAATTGCCATGTGAACACCCACTGTGACAGCAAACTAAAGCGGCATCAGTGTGCAAAGTGTCCGGGGAAGTTTATGTGGCCAGAGAATCAGCACAGGCACGCCTGCTCCCATCGTGACGAGGAAGCGCCGTCTACCCGCCAGATTTCCTGCTCCTTGTGCGATAAATCGCTGCCCACTTTGGCACAGTTGCGCATACATTTGGTTACCCATCAGAGTAACATGAGTGGCATCGATCCGAAGCACAGTTCCGCATTCTTTCGTTCGTTTTATCCCAACGGACTGAACTGCACTCCGGAGGAGCTGGGTGTTCGCATAGCCGAAGACTTCGAGGTGCAGGACTTTGATCGCTACTACAACGCCTGCACGGGCAGTGGCCAAGAGCTGGATCTCTTTGATTCCGAGACGGAGCAGAGCGGCGACGATCGGGAGGAGGGCGAGAAGCCGACCTCCCACACCTGTTTGCTGTGTGGAAAGGTGACAAACAGACTCACGAACCTGCTGCAGCACCAGAACAGCGCCCATTCAAGGGCGACGACGACAGATCTGCCTTGTTCCTGCCAGGATTGTGGTGCTAGCTTCATAAGCGACACCCTGCTGCAACAGCACCGTCGGCGTATCTGTGGCAAGAAACATTTCCGCCATCACTGTCCCAGCTGCAATCTTCGGTTCATCTGGCCGAGCAACTACGAGCAGCATTTGAAGACCCACCATAgcaacgaggaggaggaggaggatcaaCTCAAAGACGGGGAGCAACGGGACGCCAAACTGCAGTGCGATGAGTGCGAAAAGGTATTCATCTGGCACAAGGATCTCACGCGTCACAAGCGCTTGCATCTGCCGCAGTCGGCGCAGTTCGAGTGTCCGCACTGCGATCGAAAGTTCCACCGCAAAGATGGCCTCAAGTCCCACCTGCGGACCCACACGGAAGAGCAGCTGGTGGAGCAGGCTCTCAAATCCGACAGCAGTCAGGTTCTTGGCCTGCTTTCCCGTCCAAATGGCTGTAAGCAGATCCAATGCATGATCTGTCTTTCCCGCCACTCCAAGATCTCTGATCTGCGAACCCACTTGGCCGCCCATCAATACGGTTTAAGCTTCTCTGCAGAAACTGATATTTCTAGTATCACAAAGTCCCTGTATCCAGAACTGGGAACAGCTTTGGACAGAGATGAACTGGCGGAGAGAATTATGGCAGATATCGGCATGGAAATGGAGCTGGAACGATTTATTTCCATCACCAATGAAGCTGGCTTGGAGCTCAACTTGGATAGCAGCGAGACGGAAACTGAATtcgaggaagaggaggaaaaCCAGTCCAGCCAGAACTACGCCTGCAATCTCTGTCCCATGGCGGTGAAGAGAAAGCATCAGCTGTACGCCCATCAAGTAAAGAGTCATCAGTGGGAGGAGGCACCGCTCGTTTGTTCGCACTGCCAGAGTAGGTTTGTCAGCGAATCCCTGCTGGATCATCACTACAGGACCTTCTGCGGCAATACCCAAAAGCGCTTCCAGTGCCGCAAATGTCCACTCCGCTTCCGCTGGCGTGAGAACCTGAAGCACCATTTACATTTGTCCCATCAGCAGGCTGAGATGCTAGCAGCAGATGATTCCCCCCGGACAGATGCCGAACTGCAATGTGGCGAGTGCCAGCGAACGTTTAAGATGCAGAAAGATCTCACACGGCACACCTTAATGCACGCCCGGGAGGCAACGATCTATCGGTGCCGCTGGTGTGCTCGTCGATTCTACCGCTGGGCCAATCTCCTGCAACACATCGCTCGCCACGGTATCCGGGCTAGCGAGTTGCATTATGCCGAGGCTCTCCTAGACTCCTATGGACATCCAGGCGGTCAGAAAACCGTGGAGTGCCGGGTGTGCAATGTCAGCTTCGCCAGTATTGCCGCCCTGCGTCTTCATCTGGAAACAATGCCGGCCGGAAGCCACCACGAGATCTCCTCGCTGAAGAACTACTCAATCACCAACCAAATGGGCTTCGAGCTGGAGCTGCGGGACTCTGAAACGGATGAGGAGCAGTCGAAGGCACCCGGAGTGCCTGCCTACTACACTTGCGGCATGTGCCAGCTGAGGTGTGTGCGGAAGTTCGAACTGCATCAGCACCAGCAGGCCATGCACCGGCTAGAGAAGATTCCCGACGGCTGTGACCAGTGCATCTTCAAGAGCGTCTCTCCCGACATCATTGCCCATCACAAGAGGACGCAGTGCGGGAACCAAGAGAAGCAGTTCACGTGCTCCCGCTGCGGCTACAAATTTATGTGGGAGTCGAACCTGCTTACGCACATGCAGCTGCAGCACGGAAAGCCGGACAatccggaggaggaggagggggacAAGGAGACTCCGGCAGAAGAGCCTAAGGCCGGAAGTGCGGTCTTCCAGTGTGCCCTATGCCCCAGGAAATATAACCGAAAGGATCGGCTTACAGCACACGTAAAAAAGTTCCATGGGCCCGATGGCAGGGGCAACGATGTCGTCAAGGTTCCGCCTGCGAGAGCTGCCTCTCCCAAGGAACCAAAGCGCTTCCTGTGCGCCTTCTGCGGCAAGGCGGtcagctcctcctccaacCTGATCATCCACATGCGCCGTCACACCGGCGAAAAGCCTTTCAAGTGCGAGTTCTGCGCGATGGCCTTTCCACGATCGTCGGACCTCCAGTGCCACCGGCGGACGCATACCGGAGAGCGGCCGCACGTGTGTACCGTGTGCCAGAAGGGATTCGCCCGCTCCtacaagctgcagcagcacatGCGCATCCACAGCGGCGAGCGGCCGTACAAGTGCACCTACTGCGAGAAGAGCTTCACCCAGTCCAACGACCTGACACTCCACATCCGCCGGCATACGGGAGAGCGGCCCTATCAGTGCGGCATCTGCGGGGAACGTTTCATCCAGGGAACGGCACTGAAAAATCATCGCCTGCAGCAGGGCCACTACGAGGAGGGTCAGAATTCTGGGGAGCCGACAAGGCGCACGGTTTTGGAACAGTTTGCTGTATGA
Protein Sequence: MLPSNICRTCAVQNTDLRPLSTCLASDASKSFYDALQELTQIDPLIESSSDSLPQHLCGECLRRLESAYAFVEQARKVNGELLVRLRECLDEMPIDIPQEQPIKTEVDIDEAPPKCVVNVDSAGISPGEFKWQPESDSDGESAGAASSDENEVEKKPYTLRRSARKIKQPVESDNEEPELPTEPSPSKRRRGRPPGPAKRQSMTSDGRHACNVCGKTFSWFRDMQRHARIHFEKSNAFVCDTCGKGFLRKDKYTFHLRCHEKRDAKSKALQLGNEWLFAERLYSSGRLKRIECKLCGLKCLRIQELRNHLVSHQDEESLLQLREDSDVIKEHYADQLGDFDGVKQQIIMDIAAGHLEKFASIVNFHGYELGLYDSDEESASEESKYECTVCNLPFARKHQVVRHTLEKHAQSASSELPWQRCGSCKVGFLCSRLYNCHVNTHCDSKLKRHQCAKCPGKFMWPENQHRHACSHRDEEAPSTRQISCSLCDKSLPTLAQLRIHLVTHQSNMSGIDPKHSSAFFRSFYPNGLNCTPEELGVRIAEDFEVQDFDRYYNACTGSGQELDLFDSETEQSGDDREEGEKPTSHTCLLCGKVTNRLTNLLQHQNSAHSRATTTDLPCSCQDCGASFISDTLLQQHRRRICGKKHFRHHCPSCNLRFIWPSNYEQHLKTHHSNEEEEEDQLKDGEQRDAKLQCDECEKVFIWHKDLTRHKRLHLPQSAQFECPHCDRKFHRKDGLKSHLRTHTEEQLVEQALKSDSSQVLGLLSRPNGCKQIQCMICLSRHSKISDLRTHLAAHQYGLSFSAETDISSITKSLYPELGTALDRDELAERIMADIGMEMELERFISITNEAGLELNLDSSETETEFEEEEENQSSQNYACNLCPMAVKRKHQLYAHQVKSHQWEEAPLVCSHCQSRFVSESLLDHHYRTFCGNTQKRFQCRKCPLRFRWRENLKHHLHLSHQQAEMLAADDSPRTDAELQCGECQRTFKMQKDLTRHTLMHAREATIYRCRWCARRFYRWANLLQHIARHGIRASELHYAEALLDSYGHPGGQKTVECRVCNVSFASIAALRLHLETMPAGSHHEISSLKNYSITNQMGFELELRDSETDEEQSKAPGVPAYYTCGMCQLRCVRKFELHQHQQAMHRLEKIPDGCDQCIFKSVSPDIIAHHKRTQCGNQEKQFTCSRCGYKFMWESNLLTHMQLQHGKPDNPEEEEGDKETPAEEPKAGSAVFQCALCPRKYNRKDRLTAHVKKFHGPDGRGNDVVKVPPARAASPKEPKRFLCAFCGKAVSSSSNLIIHMRRHTGEKPFKCEFCAMAFPRSSDLQCHRRTHTGERPHVCTVCQKGFARSYKLQQHMRIHSGERPYKCTYCEKSFTQSNDLTLHIRRHTGERPYQCGICGERFIQGTALKNHRLQQGHYEEGQNSGEPTRRTVLEQFAV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00491633;
90% Identity: iTF_00478137;
80% Identity: -