Basic Information

Insect: Drosophila anomelani
Gene Symbol: ZNF296
Assembly: GCA_035045905.1
Location: JAWNOO010000007.1:26091099-26095526[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 24 0.0015 0.14 13.0 1.2 1 23 209 231 209 231 0.96

2 24 2.4 2.2e+02 2.9 3.8 1 21 238 258 238 260 0.84

3 24 0.0053 0.47 11.3 1.0 2 23 292 313 291 313 0.95

4 24 0.00081 0.072 13.9 0.5 1 23 386 409 386 409 0.94

5 24 0.0054 0.48 11.3 0.0 2 23 484 505 483 505 0.96

6 24 0.001 0.092 13.5 1.2 1 23 586 609 586 609 0.96

7 24 0.0024 0.21 12.4 0.5 2 22 620 640 619 640 0.93

8 24 0.19 17 6.4 4.6 1 23 649 671 649 672 0.94

9 24 0.00073 0.065 14.0 1.5 2 23 691 712 690 712 0.97

10 24 4.8e-06 0.00043 20.9 4.3 1 23 719 741 719 741 0.98

11 24 0.0015 0.13 13.0 0.7 1 23 876 899 876 899 0.96

12 24 0.0058 0.52 11.2 0.8 2 22 907 927 906 927 0.95

13 24 0.029 2.6 9.0 3.3 1 23 936 959 936 959 0.93

14 24 3.8e-05 0.0033 18.1 1.4 2 23 978 999 977 999 0.97

15 24 9e-05 0.008 16.9 0.4 1 23 1006 1028 1006 1028 0.98

16 24 0.085 7.6 7.5 0.0 2 21 1055 1074 1054 1075 0.92

17 24 0.036 3.2 8.7 4.0 1 23 1121 1144 1121 1144 0.96

18 24 0.016 1.4 9.8 1.2 1 23 1181 1204 1181 1204 0.96

19 24 0.00036 0.032 15.0 1.7 1 23 1230 1253 1230 1253 0.97

20 24 5.3e-06 0.00047 20.7 0.2 2 23 1280 1301 1279 1301 0.95

21 24 0.0027 0.24 12.2 2.6 1 23 1307 1329 1307 1329 0.99

22 24 2.1e-06 0.00018 22.0 2.0 1 23 1335 1357 1335 1357 0.97

23 24 1.8e-07 1.6e-05 25.3 2.4 1 23 1363 1385 1363 1385 0.99

24 24 0.00068 0.061 14.1 0.1 1 21 1391 1411 1391 1415 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	24	0.0015	0.14	13.0	1.2	1	23	209	231	209	231	0.96
2	24	2.4	2.2e+02	2.9	3.8	1	21	238	258	238	260	0.84
3	24	0.0053	0.47	11.3	1.0	2	23	292	313	291	313	0.95
4	24	0.00081	0.072	13.9	0.5	1	23	386	409	386	409	0.94
5	24	0.0054	0.48	11.3	0.0	2	23	484	505	483	505	0.96
6	24	0.001	0.092	13.5	1.2	1	23	586	609	586	609	0.96
7	24	0.0024	0.21	12.4	0.5	2	22	620	640	619	640	0.93
8	24	0.19	17	6.4	4.6	1	23	649	671	649	672	0.94
9	24	0.00073	0.065	14.0	1.5	2	23	691	712	690	712	0.97
10	24	4.8e-06	0.00043	20.9	4.3	1	23	719	741	719	741	0.98
11	24	0.0015	0.13	13.0	0.7	1	23	876	899	876	899	0.96
12	24	0.0058	0.52	11.2	0.8	2	22	907	927	906	927	0.95
13	24	0.029	2.6	9.0	3.3	1	23	936	959	936	959	0.93
14	24	3.8e-05	0.0033	18.1	1.4	2	23	978	999	977	999	0.97
15	24	9e-05	0.008	16.9	0.4	1	23	1006	1028	1006	1028	0.98
16	24	0.085	7.6	7.5	0.0	2	21	1055	1074	1054	1075	0.92
17	24	0.036	3.2	8.7	4.0	1	23	1121	1144	1121	1144	0.96
18	24	0.016	1.4	9.8	1.2	1	23	1181	1204	1181	1204	0.96
19	24	0.00036	0.032	15.0	1.7	1	23	1230	1253	1230	1253	0.97
20	24	5.3e-06	0.00047	20.7	0.2	2	23	1280	1301	1279	1301	0.95
21	24	0.0027	0.24	12.2	2.6	1	23	1307	1329	1307	1329	0.99
22	24	2.1e-06	0.00018	22.0	2.0	1	23	1335	1357	1335	1357	0.97
23	24	1.8e-07	1.6e-05	25.3	2.4	1	23	1363	1385	1363	1385	0.99
24	24	0.00068	0.061	14.1	0.1	1	21	1391	1411	1391	1415	0.91

Sequence Information

Coding Sequence: ATGCTTCCCTTAAATATTTGCCGCACTTGTGCGGTCCAGAACACGGATTTGCGGCCATTGTCCACCTGTCTGGCCAACGACGCCTCAAAAAGTTTCTATGAAGCGCTCCAGGAGCTAACGCAAATCGATCCCCTGATTGAGAGCTCGAGTGACAGTCTGCCGCAGCATCTGTGCTACGAATGCCTGAGGAGATTGGAATCTGCTTACGCCTTTGTGGAACAGGCCAGGAAAGTCAATGGCGAGCTGTTGGTTCGCCTGCGGGAATGCCTCGACGAAATGCCCATTGACATTCCCCAGGAGCAGCACATTAAAACCGAAGTAGATATCGATGAGGCGACTCCCAAGTGTATTGTGGATGTAGATTCCACCGGTGTATCTCCTGGGAAGTTCAAATGGCAACCGGAAAGCGATAACGATAGAGAATCTGCTGGAGCAGCATCCAGTGAAGAGAATGAGGTCGAGAAGAAGCCCTATACTCTAAGACGCAGTGCGCGGAAAATCAAGCAGCCTGTAGAGACTGATAATGAGGAAACAGAGTTACCCACAGAACCATCGCCCAGCAAACGCCGCCGTGGCCGTCCGCCCGGCCCGGCCAAGCGCCAGTCAATGACCTCCGATGGACGCCATGCCTGCAATGTGTGTGGCAAGACCTTCTCGTGGTTCCGGGATATGCAGCGCCATGCCCGCATCCATTTCGAGAAATCCAACGCTTTCGTTTGTGACACTTGCGGCAAGGGATTCCTGCGCAAAGACAAGTACACATTCCACCTGCGCTGCCACGAAAAGCGCGAAGCGAAATGCAAGGCTCTGCAGCTGGGAAACGAGTGGCTTTTCGCCGAACGGCTCTACAGTTCCGGCAGGCTAAAGAGGATCGAGTGCAAGCTGTGTGGCCTGAGGTGTTCGCGAATTCAGGAGCTGAGAAATCACTTGGTCAGCCATCAAAGCGAGGAGAGCCTGCTCCAGTTGAGGGAGGATAGCGATGTTATTAAGAAGCACTATGCCGACCAGCCTGGCGACTTGGACGGCGTCAAGCAGCAAATTATCAAGGACATAGCGGCGGGGCACTTGGAGAAGTTCGCTTCCATAGTGAATTTCCATGGCTACGAGTTGGGATTGTGTGACTCGGACGAAGAATCTGCCAGCGAAGAGTCTAAATATGAATGCACTGTCTGCAATCTTCCCTTTGCACGGAAACATCAAGTGGTGAGGCATACGCTGGAGGAGCACGGCCAATCCTCTTCTTCAGAGTTGCCCTGGCAACGTTGCGGCTCCTGTAAAGTCGGCTTCCTCTGCTCCAGACTGTACAATTGCCATGTAAACACCCACTGTGACAGCAAACTAAAGCGGTATCAATGTGCAAAGTGTCCGGGGAAGTTTATGTGGCCGGAGAATCAGCACAGGCACGCCTGCTCCCACCTTCACGAGGAAGCGCCGTCTACTCGCCAGATTTCCTGCTCCTTGTGCGATGAATCGTTGCCCACATTGGCCCAGTTGCGCATACATCTGGTTACTCACCAGAGTAACATGAGTGGCATCGATCCGAAGCACAGTTCCACATTCTTTCGTTCGTTTTATCCCAACGGACTGGACTGCTCTCCGGAGGAGCTGGGTGTTCGCATAGCCGAAGACTTTGAGGTGCAGGACTTTGATCGCTACTACAACGCCTGCACGGGCAGTGGCCAAGAGCTGGATCTCTTCGATTCCGAGACGGAGCAGAGCGGCGACGAACGGGAGGAGGACGAAAAGCCGACCTCTCACACCTGTTTGCTGTGTGGAAAGGTGACCAACAGACTTACAACCCTGCTGCAGCACCAAAACAGCGCCCATTCAAGGGCGACGACAAAAGATCTGCCTTGTTCCTGCCAGGATTGTGGTGCTAGCTTCATAAGCGACGCCCTGCTGCAACAGCACCGCCGGCGTATCTGCGGCAAGAAACATTTCCGCCATCACTGCCCCAGCTGCAATCTCCGGTTCATCTGGCCGAGCAACTACGATCTCCATATGAAGACCCATCATAGCAACGGAGAGGAGGATCAACTAGAAGAGGGGGAGCAACGGGACGCCAAACTGCAGTGCGATGAGTGCGACAAGGTCTTCATCTGGCACAAGGATCTCACGCGTCACAAGCGCTTGCACCTGCCGCAGTCGGCGCAGTTCGAGTGTCCGCATTGCGATCGAAAGTTTCACCGAAAGGATGGCCTCAAGTCCCACCTGCGGGTCCACACGGAAGAGCAGCTGGTTGAGCAGGCTCTCAAATCCGACAGCAGTCAGGTCCTTGCCCTGCTTTCCCGTCCCAATGGCTGTAAGCAGATCCAATGCATGATCTGTCTTTCCCGCCACTCCAAGATCTCTGATCTGCGAACCCACTTGTCCGCCCATCAATGCGGATTAAGCTTCTCCGCAGAGACTGATATTTCAAGTATTCTAAAGTCCCTTTACCCAGAACTGGGCACAGCCTTGGACAGAGATGAACTGGCGGAGAGGATTATGGCAGATATCGACACGGGAATGGAGCTGGAACGATTTATTTCCATCACCAATGAGACTGGTTTGGAGCTCAACTTGGATAGCAGCGAAACGGACACTGAATTCGAAGAAGAGGAGGAGCACCAGGCCAGCCAGAGCTACGCCTGCAATCTCTGTCCCATGGCGGTGAAGAGAAAGCATCAGCTGTACGCCCACCAAGCTAAGAGTCATCAGTGGGAGGAGGCAGCGCTCGTTTGTTCGCACTGCCAGGCTAGGTTTGTCAGCGAATCCCTGCTGGATCATCACTACAGGACCTTCTGCGGCAATACCCAGAAGCGCTTTCAGTGCCGCAAATGTCCGCTCCGCTTCCGCTGGCGTGAGAACCTGAAGCACCATCTTTATTTGTCCCATCAGCAGGCCGAGATTCAAGCAGCAGAAGATTCCCCTCGAACAGATGCCGAACTGCAATGTGGCGAGTGCCAGCGAACTTTCAAGATGCAAAAGGATCTCACACGGCACACCTTGATGCACGCCCGGGAGGCGACGATCTATCGGTGCCGCTGGTGCGCTCGTCGTTTCTACCGCTGGGCCAATCTCCTGCAACACATCGCTCGCCACGGCATACGGGCTAGTGAGTTGCATTATGCCGAGGCCCTCCTAGACTCCTATGGACATCCAGGCGGTCAGAAGACCGTGGAGTGCCGGGTGTGCAATGTCAGCTTCGCCAGTATCGCCGCCCTGCGCCTGCACCTGGAAACCATGCCGGCCGGGAGCCACCACGAGATCTCCTCGTTGAAGAACTACTCAATCACCAACCAAATGGGCTTCGAGCTGGAGCTGCAGGACTCTGAAACGGATGAGGAGCAGTCAAAGCCACCCGGAGTGCCTGCCTACTACACTTGCGGCATGTGCCAGCTGAGGTGCGTGCGAAAGTTCGAACTGCACCAACACCAGCAGGCGATGCATCGCTTGGAGAAGATTCCCGACGGCTGTGACCAGTGCATCTTCAAGAGCGTCTGTCCCGACATCATTGCCCACCACAAGAGGACGCAGTGCGGAAACGGAGAGAAGCAGTTCACGTGCTTCCGCTGCGGCTACAAATTTATGTGGGAGTCGAACCTGCTTACGCACATGCAGTTGCAGCACGGAAAACCGGACAatccagaggaggaggaggacaagGAGACTCCGGCAGAGGAGCCTAAGGCCGGAAGCGCGGTCTTCCAGTGTGCCCAATGCCCCAGGAAATACAACCGAAAGGATCGCCTTACAGCGCACGTGAAAAAGTTCCATGGGCCCGATGGCCGGGGCCCCGAAGTCGTCAAGGTTCCGCCTACTAGAGCCGCCTCTCCCAAGGAACCGAAGCGCTTCCTCTGCGCCTTCTGCGGCAAGGCGGTCAGCTCGTCCTCCAACCTGATCATCCACATGCGCCGTCACACCGGCGAAAAGCCTTTCAAGTGTGAGTTCTGCGCGATGGCCTTTCCACGATCGTCGGACCTCCAGTGCCACCGGCGGACGCACACCGGAGAGCGGCCGCACGTGTGTACCGTGTGCCAGAAGGGATTCGCCCGCTCCTAcaagctgcagcagcacaTGCGCATCCACAGTGGCGAGCGACCGTACAAGTGCACCTACTGCGAGAAGAGCTTCACCCAGTCCAACGACCTGACACTCCACATCCGTCGGCACACGGGAGAGCGGCCCTACCAGTGCGGCATCTGCGGGGAACGTTTCATCCAGGGAACGGCGCTGAAAAATCATCGCCTGCAGCAGGGCCACTACGAGGAGGGTCAGAATTCTGGGGAGCCGGCAAGGCGCACGGTTTTGGAACAGTTTGCTGTATGA
Protein Sequence: MLPLNICRTCAVQNTDLRPLSTCLANDASKSFYEALQELTQIDPLIESSSDSLPQHLCYECLRRLESAYAFVEQARKVNGELLVRLRECLDEMPIDIPQEQHIKTEVDIDEATPKCIVDVDSTGVSPGKFKWQPESDNDRESAGAASSEENEVEKKPYTLRRSARKIKQPVETDNEETELPTEPSPSKRRRGRPPGPAKRQSMTSDGRHACNVCGKTFSWFRDMQRHARIHFEKSNAFVCDTCGKGFLRKDKYTFHLRCHEKREAKCKALQLGNEWLFAERLYSSGRLKRIECKLCGLRCSRIQELRNHLVSHQSEESLLQLREDSDVIKKHYADQPGDLDGVKQQIIKDIAAGHLEKFASIVNFHGYELGLCDSDEESASEESKYECTVCNLPFARKHQVVRHTLEEHGQSSSSELPWQRCGSCKVGFLCSRLYNCHVNTHCDSKLKRYQCAKCPGKFMWPENQHRHACSHLHEEAPSTRQISCSLCDESLPTLAQLRIHLVTHQSNMSGIDPKHSSTFFRSFYPNGLDCSPEELGVRIAEDFEVQDFDRYYNACTGSGQELDLFDSETEQSGDEREEDEKPTSHTCLLCGKVTNRLTTLLQHQNSAHSRATTKDLPCSCQDCGASFISDALLQQHRRRICGKKHFRHHCPSCNLRFIWPSNYDLHMKTHHSNGEEDQLEEGEQRDAKLQCDECDKVFIWHKDLTRHKRLHLPQSAQFECPHCDRKFHRKDGLKSHLRVHTEEQLVEQALKSDSSQVLALLSRPNGCKQIQCMICLSRHSKISDLRTHLSAHQCGLSFSAETDISSILKSLYPELGTALDRDELAERIMADIDTGMELERFISITNETGLELNLDSSETDTEFEEEEEHQASQSYACNLCPMAVKRKHQLYAHQAKSHQWEEAALVCSHCQARFVSESLLDHHYRTFCGNTQKRFQCRKCPLRFRWRENLKHHLYLSHQQAEIQAAEDSPRTDAELQCGECQRTFKMQKDLTRHTLMHAREATIYRCRWCARRFYRWANLLQHIARHGIRASELHYAEALLDSYGHPGGQKTVECRVCNVSFASIAALRLHLETMPAGSHHEISSLKNYSITNQMGFELELQDSETDEEQSKPPGVPAYYTCGMCQLRCVRKFELHQHQQAMHRLEKIPDGCDQCIFKSVCPDIIAHHKRTQCGNGEKQFTCFRCGYKFMWESNLLTHMQLQHGKPDNPEEEEDKETPAEEPKAGSAVFQCAQCPRKYNRKDRLTAHVKKFHGPDGRGPEVVKVPPTRAASPKEPKRFLCAFCGKAVSSSSNLIIHMRRHTGEKPFKCEFCAMAFPRSSDLQCHRRTHTGERPHVCTVCQKGFARSYKLQQHMRIHSGERPYKCTYCEKSFTQSNDLTLHIRRHTGERPYQCGICGERFIQGTALKNHRLQQGHYEEGQNSGEPARRTVLEQFAV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00491633;
90% Identity: iTF_00488787; iTF_00541196;
80% Identity: -